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The map label for this gene is dsbD [H]

Identifier: 91789360

GI number: 91789360

Start: 3704086

End: 3706014

Strand: Direct

Name: dsbD [H]

Synonym: Bpro_3506

Alternate gene names: 91789360

Gene position: 3704086-3706014 (Clockwise)

Preceding gene: 91789359

Following gene: 91789361

Centisome position: 71.23

GC content: 66.51

Gene sequence:

>1929_bases
ATGACCTCACGATCATTGCGCTGCACCTCGGCTCGCGTCGCACGCTGCCTTCCTGGACTGCTGCTTGCCGCGTCTGCTGC
GGCCTATGCCCAATCCGATGCATCCGCGCCCCCTGTGTCGCCGCCGCCCGGATTCTCGGCCGCAGCGTCGGGGCCGATTG
ACTCGATCCGGAAGTGGTTGAATGTTCCCAGCTCGGAGCCCGAGTTGCTGCCACCGGAACAGGCGTTCCAGATTGCGGTG
CGGGCGAGCGATGCGAACAGGCTGGTCGCCGAATTGACGCCGGCGCCGAACTACTACCTCTACCGCGACCGTATCAGCTT
CAGCGTTGTCCAACCACCGACGGTCGCCATCGCCAAGGTGACGCTGCCCAAGGGGGAGCCCAAGACCGATCCCACGTTCG
GGACGGTGGAAGTGTTCCGCCGCCCGGTCGAGGCAATCATTGACTTGAAGCGGCCGGATGGGCAAGAGAGCCCGATCCAG
CTGCGCACCACGTACCAGGGCTGCAATGAACCGCTGGGCGTTTGCTACCCGCCGATCGAGAAAACGTTCACCGTAGCGCT
ACTTGGCATCGCCTCGCCCGCTGAACCTTCGCCGGTGCCTGTGGCCGATGCATCGGGCTTGCCGACCGGCGGTCCGTCGG
ACGACGGGCATATTCGCCAGCTGTTCATGCGCGGCAGTGTCTGGGCGCTGGTCGCAGCCTTCTTCGGCTTCGGTCTGTTG
CTGGCGTTCACGCCCTGCATGCTGCCGATGATCCCCATCCTGTCCGGCATCATCGCCGGACAGGAACCGCACATGACGCG
GCGCCACGCCCTCGGCCTGTCGTTGGTTTACGTTCTGGGGATGGCGATCACCTACGCGCTGGCCGGCGTGGCGGCGGGGC
TCGCGGGCACGCTGCTGTCCGCGTACCTGCAAAACCCCTGGGTGCTGGGCGGCTTCGCCGCGATCTTCGTGCTGCTGGCG
CTGTCGATGTTCGGCCTGTTCGAACTGCAGTTGCCCGCATCCCTGCAAAGTCGGCTGGCCCGTGCGGGCAGCCGGCTCAA
GGGAGGCAGGGTGGCCGGCGTGTTTCTGATGGGGGTACTGTCGGCGGTGATCGTCGGGCCCTGCGTCGCCGCCCCGCTAG
CGGGCGCGTTGCTGTACATCGGTCAGACGCGCGACATCGCCCTGGGCGGCGTGGCTTTGTTCTCGCTGGCCATCGGCATG
GGTGCTCCGCTGCTCGTGGTCGGCGCCACGGCCGGCACTTTGCTGCTGAAGGCCGGCGCCTGGATGGAGTCGGTCAAGCG
GCTCTTCGGCGTGGTGATGCTGGCGGTGGCGATTTATCTCGTCTCACCAGTGATTCCGGTCGTCGTGCAGCAACTGCTGT
GGGCGGCTCTGCTGGTGGTGTCGGCCATCTACTTGCACGCCCTCGACCCGTTGCCGACCGACGCGCCGGGCTATAGGCGC
CTTTTCAAGGGTGTGGGCGTGCTGGCGCTGCTGACGGGTGCGGCCCTGATGGTAGGCGTGCTTTCGGGCCATCGCGAGAT
CCTGCGGCCGCTGGCTGGCATCCGTGGCACCGCCAACATCGAGCGACGGGAACTCACTTTCCAGCCCGTGAACAGCGTGT
CCGAACTGGAGAGCCGGCTGGGGGCGGCCCGGGGCCAGGTCGTGATGCTGGATTTCTGGGCCGAGTGGTGCGTGTCGTGC
AAGGAAATGGACCGCTTTACCTTCAGCGATCCGCGGGTTCAGACCCGCTTGAAGGATGCGGTACTGCTGCGTGCCGACGT
CACCGCCAACACCCCGGATCACCACGCGCTGCTGCAGCGGTTCTCGTTGTTCGGACCACCGGGCATCGTGTTCTTCGACA
AGCAGGGCCGGGAGGTGGCCTTCCGCGTGATCGGGTACCAGGCTCCGGAGCAGTTCATGGCATCGCTGGACCGGGCGCTG
GCGCCGTGA

Upstream 100 bases:

>100_bases
TCACCGGCACCCCGACGACAATACTCGCGGATGGGCGCCGATTGGTCGGCGCCGTCCCTCGCGCCGAGCTGGAAGCGCAG
CTGCAGAAAGCGGCAAAACG

Downstream 100 bases:

>100_bases
ACTTGCGAGCCCTACAGAACCCACGTGCCCAAGCGGCCTCATCTGCCGAGTGCTCGACGCTGCACGGCCACGCTGCTGAC
AGAGCCCAACGATCGCGATG

Product: protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MTSRSLRCTSARVARCLPGLLLAASAAAYAQSDASAPPVSPPPGFSAAASGPIDSIRKWLNVPSSEPELLPPEQAFQIAV
RASDANRLVAELTPAPNYYLYRDRISFSVVQPPTVAIAKVTLPKGEPKTDPTFGTVEVFRRPVEAIIDLKRPDGQESPIQ
LRTTYQGCNEPLGVCYPPIEKTFTVALLGIASPAEPSPVPVADASGLPTGGPSDDGHIRQLFMRGSVWALVAAFFGFGLL
LAFTPCMLPMIPILSGIIAGQEPHMTRRHALGLSLVYVLGMAITYALAGVAAGLAGTLLSAYLQNPWVLGGFAAIFVLLA
LSMFGLFELQLPASLQSRLARAGSRLKGGRVAGVFLMGVLSAVIVGPCVAAPLAGALLYIGQTRDIALGGVALFSLAIGM
GAPLLVVGATAGTLLLKAGAWMESVKRLFGVVMLAVAIYLVSPVIPVVVQQLLWAALLVVSAIYLHALDPLPTDAPGYRR
LFKGVGVLALLTGAALMVGVLSGHREILRPLAGIRGTANIERRELTFQPVNSVSELESRLGAARGQVVMLDFWAEWCVSC
KEMDRFTFSDPRVQTRLKDAVLLRADVTANTPDHHALLQRFSLFGPPGIVFFDKQGREVAFRVIGYQAPEQFMASLDRAL
AP

Sequences:

>Translated_642_residues
MTSRSLRCTSARVARCLPGLLLAASAAAYAQSDASAPPVSPPPGFSAAASGPIDSIRKWLNVPSSEPELLPPEQAFQIAV
RASDANRLVAELTPAPNYYLYRDRISFSVVQPPTVAIAKVTLPKGEPKTDPTFGTVEVFRRPVEAIIDLKRPDGQESPIQ
LRTTYQGCNEPLGVCYPPIEKTFTVALLGIASPAEPSPVPVADASGLPTGGPSDDGHIRQLFMRGSVWALVAAFFGFGLL
LAFTPCMLPMIPILSGIIAGQEPHMTRRHALGLSLVYVLGMAITYALAGVAAGLAGTLLSAYLQNPWVLGGFAAIFVLLA
LSMFGLFELQLPASLQSRLARAGSRLKGGRVAGVFLMGVLSAVIVGPCVAAPLAGALLYIGQTRDIALGGVALFSLAIGM
GAPLLVVGATAGTLLLKAGAWMESVKRLFGVVMLAVAIYLVSPVIPVVVQQLLWAALLVVSAIYLHALDPLPTDAPGYRR
LFKGVGVLALLTGAALMVGVLSGHREILRPLAGIRGTANIERRELTFQPVNSVSELESRLGAARGQVVMLDFWAEWCVSC
KEMDRFTFSDPRVQTRLKDAVLLRADVTANTPDHHALLQRFSLFGPPGIVFFDKQGREVAFRVIGYQAPEQFMASLDRAL
AP
>Mature_641_residues
TSRSLRCTSARVARCLPGLLLAASAAAYAQSDASAPPVSPPPGFSAAASGPIDSIRKWLNVPSSEPELLPPEQAFQIAVR
ASDANRLVAELTPAPNYYLYRDRISFSVVQPPTVAIAKVTLPKGEPKTDPTFGTVEVFRRPVEAIIDLKRPDGQESPIQL
RTTYQGCNEPLGVCYPPIEKTFTVALLGIASPAEPSPVPVADASGLPTGGPSDDGHIRQLFMRGSVWALVAAFFGFGLLL
AFTPCMLPMIPILSGIIAGQEPHMTRRHALGLSLVYVLGMAITYALAGVAAGLAGTLLSAYLQNPWVLGGFAAIFVLLAL
SMFGLFELQLPASLQSRLARAGSRLKGGRVAGVFLMGVLSAVIVGPCVAAPLAGALLYIGQTRDIALGGVALFSLAIGMG
APLLVVGATAGTLLLKAGAWMESVKRLFGVVMLAVAIYLVSPVIPVVVQQLLWAALLVVSAIYLHALDPLPTDAPGYRRL
FKGVGVLALLTGAALMVGVLSGHREILRPLAGIRGTANIERRELTFQPVNSVSELESRLGAARGQVVMLDFWAEWCVSCK
EMDRFTFSDPRVQTRLKDAVLLRADVTANTPDHHALLQRFSLFGPPGIVFFDKQGREVAFRVIGYQAPEQFMASLDRALA
P

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=577, Percent_Identity=38.9948006932409, Blast_Score=344, Evalue=9e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 68153; Mature: 68022

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRSLRCTSARVARCLPGLLLAASAAAYAQSDASAPPVSPPPGFSAAASGPIDSIRKWL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NVPSSEPELLPPEQAFQIAVRASDANRLVAELTPAPNYYLYRDRISFSVVQPPTVAIAKV
CCCCCCCCCCCCHHHHEEEEEECCCHHHHHCCCCCCCEEEEECCCEEEEECCCCEEEEEE
TLPKGEPKTDPTFGTVEVFRRPVEAIIDLKRPDGQESPIQLRTTYQGCNEPLGVCYPPIE
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCH
KTFTVALLGIASPAEPSPVPVADASGLPTGGPSDDGHIRQLFMRGSVWALVAAFFGFGLL
HHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
LAFTPCMLPMIPILSGIIAGQEPHMTRRHALGLSLVYVLGMAITYALAGVAAGLAGTLLS
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLQNPWVLGGFAAIFVLLALSMFGLFELQLPASLQSRLARAGSRLKGGRVAGVFLMGVL
HHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SAVIVGPCVAAPLAGALLYIGQTRDIALGGVALFSLAIGMGAPLLVVGATAGTLLLKAGA
HHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
WMESVKRLFGVVMLAVAIYLVSPVIPVVVQQLLWAALLVVSAIYLHALDPLPTDAPGYRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LFKGVGVLALLTGAALMVGVLSGHREILRPLAGIRGTANIERRELTFQPVNSVSELESRL
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHEEECCCCCHHHHHHHHH
GAARGQVVMLDFWAEWCVSCKEMDRFTFSDPRVQTRLKDAVLLRADVTANTPDHHALLQR
HHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCCCHHHHHHHH
FSLFGPPGIVFFDKQGREVAFRVIGYQAPEQFMASLDRALAP
HHHCCCCCEEEECCCCCEEEEHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSRSLRCTSARVARCLPGLLLAASAAAYAQSDASAPPVSPPPGFSAAASGPIDSIRKWL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NVPSSEPELLPPEQAFQIAVRASDANRLVAELTPAPNYYLYRDRISFSVVQPPTVAIAKV
CCCCCCCCCCCCHHHHEEEEEECCCHHHHHCCCCCCCEEEEECCCEEEEECCCCEEEEEE
TLPKGEPKTDPTFGTVEVFRRPVEAIIDLKRPDGQESPIQLRTTYQGCNEPLGVCYPPIE
ECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCH
KTFTVALLGIASPAEPSPVPVADASGLPTGGPSDDGHIRQLFMRGSVWALVAAFFGFGLL
HHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
LAFTPCMLPMIPILSGIIAGQEPHMTRRHALGLSLVYVLGMAITYALAGVAAGLAGTLLS
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLQNPWVLGGFAAIFVLLALSMFGLFELQLPASLQSRLARAGSRLKGGRVAGVFLMGVL
HHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SAVIVGPCVAAPLAGALLYIGQTRDIALGGVALFSLAIGMGAPLLVVGATAGTLLLKAGA
HHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
WMESVKRLFGVVMLAVAIYLVSPVIPVVVQQLLWAALLVVSAIYLHALDPLPTDAPGYRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LFKGVGVLALLTGAALMVGVLSGHREILRPLAGIRGTANIERRELTFQPVNSVSELESRL
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHEEECCCCCHHHHHHHHH
GAARGQVVMLDFWAEWCVSCKEMDRFTFSDPRVQTRLKDAVLLRADVTANTPDHHALLQR
HHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEECCCCCCCHHHHHHHH
FSLFGPPGIVFFDKQGREVAFRVIGYQAPEQFMASLDRALAP
HHHCCCCCEEEECCCCCEEEEHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]