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The map label for this gene is nuoD [H]

Identifier: 91789113

GI number: 91789113

Start: 3444225

End: 3445478

Strand: Reverse

Name: nuoD [H]

Synonym: Bpro_3253

Alternate gene names: 91789113

Gene position: 3445478-3444225 (Counterclockwise)

Preceding gene: 91789114

Following gene: 91789112

Centisome position: 66.26

GC content: 60.05

Gene sequence:

>1254_bases
ATGGCTGAAATCAAAAACTACACGCTCAATTTTGGACCGCAGCATCCGGCGGCACATGGCGTTTTGCGCCTGGTGCTGGA
GCTTGACGGCGAGGTGATCCAGCGCGCCGACCCGCACATCGGTCTGCTGCACCGCGCGACTGAAAAACTGGCCGAAAGCA
AAACCTACATCCAGTCACTGCCCTACATGGACAGGCTCGACTATGTGTCGATGATGTCCAATGAGCAGGCCTATTGCCTG
GCCATCGAGAAATTGCTGGGCGTGGATGTGCCCATACGTGCGCAATACATCCGGGTGATGTACGCGGAAATCACGCGCCT
GCTCAACCACCTGCTGTGGTTGGGCGCGCACGGTTTCGACTGCGGCGCGATGAACATCCTGATTTACTGCTTTCGCGAAC
GCGAGGCGCTGTTTGACATGTACGAGGCCGTTTCGGGTGCGCGCATGCATGCGGCCTACTTCCGGCCGGGGGGCGTTTAC
CGCGACCTGCCCGATACCATGCCGCAGTACCGCGTCAGCAAGATCAAGAACGCCAAGGCCATTGCCGCGCTGAACGAAAA
CCGCCAGGGGTCCCTGCTCGATTTCATCGATGACTTCGTGGCCAAGTTCCCGCGGCTGGTGGACGAGTACGAAACGCTGC
TGACCGACAACCGCATCTGGAAGCAGCGCACGGTGGGCGTCGGGGTCGTGTCGCCCGAGCGCGCGCTCAACCTCGGTTTC
ACCGGCCCTATGCTCCGGGGCTCCGGCTTCGCCTGGGACCTGCGCAAGCAGCAGCCCTACGATGTCTACGACCGTATGGA
TTTCGACATTCCCGTTGGAAAGACCGGCGATTGCTACGACCGCTACCTGGTTCGCATCGAAGAGATGCGCCAGTCCAACC
GCATCATCAAGCAGTGCATCGACTGGCTGCGCGTCAACCCTGGCCCGGTGATCACCAGCAACCACAAGGTCGCGGCGCCT
GACCGTGAATCCATGAAGACCAACATGGAAGAGCTGATTCACCACTTCAAGCTTTTCACTGAAGGTTTTCACGTGCCCGA
AGGCGAGGCCTATGCCGCGGTCGAGCATCCCAAGGGCGAGTTCGGCATCTACATCGTCAGCGATGGTGCCAACAAGCCAT
ACCGCCTGAAAATCCGCCCGCCCGGCTTTCCGCACCTGGCGGCCATGGACGAAATGTCGCGCGGCCACATGATTGCCGAC
GCCGTCGCCGTGATCGGCACCATGGACATTGTGTTCGGTGAAATTGATCGCTAA

Upstream 100 bases:

>100_bases
CCTGCGGCAGTTCGCTGCCCCTTGCACTAAAGAGTGGGGCGCTGCCTTGCTTGGGGCGGCCCGGCGCGGCAGCATTAGCA
CTGCAAAAATTTGGTAGACC

Downstream 100 bases:

>100_bases
AACTGATGATTTCAACCATGATTTCTGAACAAACCAAAGCCCGTTTTGACCGCGAGGTTGCCAAGTACCCGGCGGACCAG
AAGCAGTCGGCCGTGATGGC

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTYIQSLPYMDRLDYVSMMSNEQAYCL
AIEKLLGVDVPIRAQYIRVMYAEITRLLNHLLWLGAHGFDCGAMNILIYCFREREALFDMYEAVSGARMHAAYFRPGGVY
RDLPDTMPQYRVSKIKNAKAIAALNENRQGSLLDFIDDFVAKFPRLVDEYETLLTDNRIWKQRTVGVGVVSPERALNLGF
TGPMLRGSGFAWDLRKQQPYDVYDRMDFDIPVGKTGDCYDRYLVRIEEMRQSNRIIKQCIDWLRVNPGPVITSNHKVAAP
DRESMKTNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYIVSDGANKPYRLKIRPPGFPHLAAMDEMSRGHMIAD
AVAVIGTMDIVFGEIDR

Sequences:

>Translated_417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTYIQSLPYMDRLDYVSMMSNEQAYCL
AIEKLLGVDVPIRAQYIRVMYAEITRLLNHLLWLGAHGFDCGAMNILIYCFREREALFDMYEAVSGARMHAAYFRPGGVY
RDLPDTMPQYRVSKIKNAKAIAALNENRQGSLLDFIDDFVAKFPRLVDEYETLLTDNRIWKQRTVGVGVVSPERALNLGF
TGPMLRGSGFAWDLRKQQPYDVYDRMDFDIPVGKTGDCYDRYLVRIEEMRQSNRIIKQCIDWLRVNPGPVITSNHKVAAP
DRESMKTNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYIVSDGANKPYRLKIRPPGFPHLAAMDEMSRGHMIAD
AVAVIGTMDIVFGEIDR
>Mature_416_residues
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTYIQSLPYMDRLDYVSMMSNEQAYCLA
IEKLLGVDVPIRAQYIRVMYAEITRLLNHLLWLGAHGFDCGAMNILIYCFREREALFDMYEAVSGARMHAAYFRPGGVYR
DLPDTMPQYRVSKIKNAKAIAALNENRQGSLLDFIDDFVAKFPRLVDEYETLLTDNRIWKQRTVGVGVVSPERALNLGFT
GPMLRGSGFAWDLRKQQPYDVYDRMDFDIPVGKTGDCYDRYLVRIEEMRQSNRIIKQCIDWLRVNPGPVITSNHKVAAPD
RESMKTNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYIVSDGANKPYRLKIRPPGFPHLAAMDEMSRGHMIADA
VAVIGTMDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=414, Percent_Identity=60.3864734299517, Blast_Score=516, Evalue=1e-146,
Organism=Homo sapiens, GI260898743, Length=408, Percent_Identity=59.8039215686275, Blast_Score=501, Evalue=1e-142,
Organism=Escherichia coli, GI145693162, Length=410, Percent_Identity=36.5853658536585, Blast_Score=287, Evalue=9e-79,
Organism=Escherichia coli, GI1789076, Length=424, Percent_Identity=28.3018867924528, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788832, Length=412, Percent_Identity=27.1844660194175, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17555284, Length=414, Percent_Identity=58.2125603864734, Blast_Score=492, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17568379, Length=414, Percent_Identity=57.7294685990338, Blast_Score=490, Evalue=1e-139,
Organism=Drosophila melanogaster, GI24638644, Length=414, Percent_Identity=59.4202898550725, Blast_Score=525, Evalue=1e-149,
Organism=Drosophila melanogaster, GI221459469, Length=412, Percent_Identity=56.0679611650485, Blast_Score=481, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 47534; Mature: 47403

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTYIQSL
CCCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PYMDRLDYVSMMSNEQAYCLAIEKLLGVDVPIRAQYIRVMYAEITRLLNHLLWLGAHGFD
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
CGAMNILIYCFREREALFDMYEAVSGARMHAAYFRPGGVYRDLPDTMPQYRVSKIKNAKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHH
IAALNENRQGSLLDFIDDFVAKFPRLVDEYETLLTDNRIWKQRTVGVGVVSPERALNLGF
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECHHHHEECCC
TGPMLRGSGFAWDLRKQQPYDVYDRMDFDIPVGKTGDCYDRYLVRIEEMRQSNRIIKQCI
CCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DWLRVNPGPVITSNHKVAAPDRESMKTNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYIVSDGANKPYRLKIRPPGFPHLAAMDEMSRGHMIADAVAVIGTMDIVFGEIDR
EEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAESKTYIQSL
CCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PYMDRLDYVSMMSNEQAYCLAIEKLLGVDVPIRAQYIRVMYAEITRLLNHLLWLGAHGFD
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
CGAMNILIYCFREREALFDMYEAVSGARMHAAYFRPGGVYRDLPDTMPQYRVSKIKNAKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCHH
IAALNENRQGSLLDFIDDFVAKFPRLVDEYETLLTDNRIWKQRTVGVGVVSPERALNLGF
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECHHHHEECCC
TGPMLRGSGFAWDLRKQQPYDVYDRMDFDIPVGKTGDCYDRYLVRIEEMRQSNRIIKQCI
CCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DWLRVNPGPVITSNHKVAAPDRESMKTNMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYIVSDGANKPYRLKIRPPGFPHLAAMDEMSRGHMIADAVAVIGTMDIVFGEIDR
EEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA