Click here to switch to the map view.

The map label for this gene is nqo2 [H]

Identifier: 91789112

GI number: 91789112

Start: 3443719

End: 3444219

Strand: Reverse

Name: nqo2 [H]

Synonym: Bpro_3252

Alternate gene names: 91789112

Gene position: 3444219-3443719 (Counterclockwise)

Preceding gene: 91789113

Following gene: 91789111

Centisome position: 66.23

GC content: 59.08

Gene sequence:

>501_bases
ATGATTTCAACCATGATTTCTGAACAAACCAAAGCCCGTTTTGACCGCGAGGTTGCCAAGTACCCGGCGGACCAGAAGCA
GTCGGCCGTGATGGCCTGCCTCACGATCGTGCAGGAAGAGCAGGGCTTTGTCAGCGCCGAGAGCGAGAAGCTGGTGGCCG
AGTACCTGGGCATGACGCCGATTGCCGTGCACGAAGTCACCACCTTCTACAACATGTACAACCAGCAGCCGGTGGGCAAG
TACAAGCTCAATGTCTGCACCAACCTGCCGTGCCAGTTGCGCGATGGCGCCAGGGCGCTCAAGCATCTGGAGCACAAGCT
GGGCATTTCCATGGGCCAGACAACGGCCGACGGCCTGTTCACGCTGCAGCAGTCCGAATGCCTGGGGGCCTGCGCGGACT
CCCCGGTGATGCTGGTCAACGACCTCACGATGTGCAGCTTCATGAGCGATGAGAAACTGGACCAACTCATCGATGGTCTC
AAATCCGCCGAGGCGAAGTAA

Upstream 100 bases:

>100_bases
CGGCCATGGACGAAATGTCGCGCGGCCACATGATTGCCGACGCCGTCGCCGTGATCGGCACCATGGACATTGTGTTCGGT
GAAATTGATCGCTAAAACTG

Downstream 100 bases:

>100_bases
GCATGACGCTTTCAAGCAATACCCCTGACACTGCGGCGCAAAACGTGCTGGCGCAATTTGCGGCCACGGGCGTGCAGACC
TGTTTTCATGGCCGGCATAT

Product: NADH-quinone oxidoreductase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I chain 2; NDH-1 subunit 2 [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MISTMISEQTKARFDREVAKYPADQKQSAVMACLTIVQEEQGFVSAESEKLVAEYLGMTPIAVHEVTTFYNMYNQQPVGK
YKLNVCTNLPCQLRDGARALKHLEHKLGISMGQTTADGLFTLQQSECLGACADSPVMLVNDLTMCSFMSDEKLDQLIDGL
KSAEAK

Sequences:

>Translated_166_residues
MISTMISEQTKARFDREVAKYPADQKQSAVMACLTIVQEEQGFVSAESEKLVAEYLGMTPIAVHEVTTFYNMYNQQPVGK
YKLNVCTNLPCQLRDGARALKHLEHKLGISMGQTTADGLFTLQQSECLGACADSPVMLVNDLTMCSFMSDEKLDQLIDGL
KSAEAK
>Mature_166_residues
MISTMISEQTKARFDREVAKYPADQKQSAVMACLTIVQEEQGFVSAESEKLVAEYLGMTPIAVHEVTTFYNMYNQQPVGK
YKLNVCTNLPCQLRDGARALKHLEHKLGISMGQTTADGLFTLQQSECLGACADSPVMLVNDLTMCSFMSDEKLDQLIDGL
KSAEAK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is menaquinone. Couples the redox reaction to proton translocation (for every

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=159, Percent_Identity=38.9937106918239, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1788621, Length=156, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17561328, Length=143, Percent_Identity=39.1608391608392, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859877, Length=136, Percent_Identity=36.7647058823529, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21355353, Length=136, Percent_Identity=36.7647058823529, Blast_Score=107, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18337; Mature: 18337

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTMISEQTKARFDREVAKYPADQKQSAVMACLTIVQEEQGFVSAESEKLVAEYLGMTP
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
IAVHEVTTFYNMYNQQPVGKYKLNVCTNLPCQLRDGARALKHLEHKLGISMGQTTADGLF
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHE
TLQQSECLGACADSPVMLVNDLTMCSFMSDEKLDQLIDGLKSAEAK
EECHHHHHHHCCCCCEEEHHHHHHHHHHCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MISTMISEQTKARFDREVAKYPADQKQSAVMACLTIVQEEQGFVSAESEKLVAEYLGMTP
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
IAVHEVTTFYNMYNQQPVGKYKLNVCTNLPCQLRDGARALKHLEHKLGISMGQTTADGLF
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHE
TLQQSECLGACADSPVMLVNDLTMCSFMSDEKLDQLIDGLKSAEAK
EECHHHHHHHCCCCCEEEHHHHHHHHHHCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020134 [H]