Click here to switch to the map view.

The map label for this gene is nuoF2 [H]

Identifier: 91789111

GI number: 91789111

Start: 3442313

End: 3443716

Strand: Reverse

Name: nuoF2 [H]

Synonym: Bpro_3251

Alternate gene names: 91789111

Gene position: 3443716-3442313 (Counterclockwise)

Preceding gene: 91789112

Following gene: 91789110

Centisome position: 66.22

GC content: 61.68

Gene sequence:

>1404_bases
ATGACGCTTTCAAGCAATACCCCTGACACTGCGGCGCAAAACGTGCTGGCGCAATTTGCGGCCACGGGCGTGCAGACCTG
TTTTCATGGCCGGCATATCGCGCCGCAAATTCTGGCAGACCTTGACGGCAGCAACTGGCGCCTGAAGGACTACGAGGCGC
GCGGTGGCTACCAGGCCCTGCGCAAGATCCTCGGCAAGGATGGCGGCGAAGGACTGACGCCGGACCAGGTGATTGCCGAG
GTCAAGGCCAGCAGCCTGCGCGGCCGTGGCGGCGCGGGTTTCCCGACGGGCTTGAAGTGGAGCTTCATGCCGCGCCAGTT
CCCCGGGCAGAAATACCTGGTCTGCAATTCGGACGAAGGTGAGCCGGGCACCTGCAAAGACCGCGACATCATGCAGTACA
ACCCGCACAGCGTGATCGAGGGCATGGCGATTGCGGCTTATGCGATGGGCATCAGCATCGGCTACAACTACATCCATGGC
GAGATCTTTGCGACCTACCGGCGTTTTGAAGAAGCGCTCGACGAGGCCCGGGCTGCCGGCCTGATCGGCGAGAAGATTCT
CGGCAGCAGCTTCACTTTCCAGCTTCATGCGTCGCATGGTTTTGGTGCCTATATTTGCGGCGAAGAAACCGCCTTGCTGG
AATCGCTGGAAGGCAAAAAAGGCCAACCCCGCTTCAAGCCGCCGTTCCCGGCCAGCTTTGGTTTGTACGGCAAACCCACC
ACCATCAACAACACCGAAACGTTCGCTGCCGTGCCGTGGATCATCCGCAATGGCGGCCAGGCCTACCTGGAGTGCGGCAA
GCCCAACAACGGCGGCACCAAGATTTACTCGGTTTCCGGTGACGTCGAGTTGCCCGGCAACTACGAGGTGCCCATGGGTA
CGCCATTTGCCAGGCTGCTGGAACTGGCGGGCGGCGTGCGCAAGGGCCGCACGCTCAAGGCGGTTATTCCCGGTGGTTCA
TCCGCGCCGGTGCTGCCGGCTTCCATCATGATGGATTGCACGATGGACTACGACTCCATCGCCAAGGCTGGCTCCATGCT
GGGCTCGGGCGCGGTGATCGTGATGGACGACAGCCGTTGCATGGTCGAGTCGCTCAAGCGCCTGTCGTACTTCTACATGC
ATGAGTCCTGCGGGCAATGCACGCCCTGCCGCGAAGGCACGGGCTGGCTGTGGCGCGTGGTGGACCGTATCCATAACGGC
CACGGCAAGCAAACCGACATGGACCTGCTCAACTCGGTGGCCGACAACATTCAGGGCCGCACGATTTGCGCGCTGGGTGA
TGCCGCTGCGATGCCGGTCCGCGCCATGATCAAGCATTTCCGCCATGAATTTGAGGCCATGATTCCGCAAAAGACGCCTC
AACCTGCTGCATCCCACATACCAGCTCAGGCTGCCCAGGCCTGA

Upstream 100 bases:

>100_bases
CGGTGATGCTGGTCAACGACCTCACGATGTGCAGCTTCATGAGCGATGAGAAACTGGACCAACTCATCGATGGTCTCAAA
TCCGCCGAGGCGAAGTAAGC

Downstream 100 bases:

>100_bases
TCGCTGAAAGAAAAAATATGGTTGAAATAGAACTCGACGGCCAGAAGGTGGAAGTGCTCGAAGGCAGCACAGTCATGCAT
GCTGCTGAAAAAGCCGGCAC

Product: NADH-quinone oxidoreductase subunit F

Products: NA

Alternate protein names: NADH dehydrogenase I subunit F 2; NDH-1 subunit F 2 [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTLSSNTPDTAAQNVLAQFAATGVQTCFHGRHIAPQILADLDGSNWRLKDYEARGGYQALRKILGKDGGEGLTPDQVIAE
VKASSLRGRGGAGFPTGLKWSFMPRQFPGQKYLVCNSDEGEPGTCKDRDIMQYNPHSVIEGMAIAAYAMGISIGYNYIHG
EIFATYRRFEEALDEARAAGLIGEKILGSSFTFQLHASHGFGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPT
TINNTETFAAVPWIIRNGGQAYLECGKPNNGGTKIYSVSGDVELPGNYEVPMGTPFARLLELAGGVRKGRTLKAVIPGGS
SAPVLPASIMMDCTMDYDSIAKAGSMLGSGAVIVMDDSRCMVESLKRLSYFYMHESCGQCTPCREGTGWLWRVVDRIHNG
HGKQTDMDLLNSVADNIQGRTICALGDAAAMPVRAMIKHFRHEFEAMIPQKTPQPAASHIPAQAAQA

Sequences:

>Translated_467_residues
MTLSSNTPDTAAQNVLAQFAATGVQTCFHGRHIAPQILADLDGSNWRLKDYEARGGYQALRKILGKDGGEGLTPDQVIAE
VKASSLRGRGGAGFPTGLKWSFMPRQFPGQKYLVCNSDEGEPGTCKDRDIMQYNPHSVIEGMAIAAYAMGISIGYNYIHG
EIFATYRRFEEALDEARAAGLIGEKILGSSFTFQLHASHGFGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPT
TINNTETFAAVPWIIRNGGQAYLECGKPNNGGTKIYSVSGDVELPGNYEVPMGTPFARLLELAGGVRKGRTLKAVIPGGS
SAPVLPASIMMDCTMDYDSIAKAGSMLGSGAVIVMDDSRCMVESLKRLSYFYMHESCGQCTPCREGTGWLWRVVDRIHNG
HGKQTDMDLLNSVADNIQGRTICALGDAAAMPVRAMIKHFRHEFEAMIPQKTPQPAASHIPAQAAQA
>Mature_466_residues
TLSSNTPDTAAQNVLAQFAATGVQTCFHGRHIAPQILADLDGSNWRLKDYEARGGYQALRKILGKDGGEGLTPDQVIAEV
KASSLRGRGGAGFPTGLKWSFMPRQFPGQKYLVCNSDEGEPGTCKDRDIMQYNPHSVIEGMAIAAYAMGISIGYNYIHGE
IFATYRRFEEALDEARAAGLIGEKILGSSFTFQLHASHGFGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPTT
INNTETFAAVPWIIRNGGQAYLECGKPNNGGTKIYSVSGDVELPGNYEVPMGTPFARLLELAGGVRKGRTLKAVIPGGSS
APVLPASIMMDCTMDYDSIAKAGSMLGSGAVIVMDDSRCMVESLKRLSYFYMHESCGQCTPCREGTGWLWRVVDRIHNGH
GKQTDMDLLNSVADNIQGRTICALGDAAAMPVRAMIKHFRHEFEAMIPQKTPQPAASHIPAQAAQA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI20149568, Length=425, Percent_Identity=48.2352941176471, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI260656005, Length=425, Percent_Identity=48.2352941176471, Blast_Score=395, Evalue=1e-110,
Organism=Escherichia coli, GI1788620, Length=417, Percent_Identity=43.1654676258993, Blast_Score=341, Evalue=6e-95,
Organism=Caenorhabditis elegans, GI17531727, Length=461, Percent_Identity=46.2039045553145, Blast_Score=403, Evalue=1e-113,
Organism=Drosophila melanogaster, GI19920794, Length=414, Percent_Identity=47.8260869565217, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI45550452, Length=428, Percent_Identity=44.8598130841121, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24653819, Length=421, Percent_Identity=36.8171021377672, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI24653817, Length=357, Percent_Identity=36.9747899159664, Blast_Score=225, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR011537
- InterPro:   IPR011538
- InterPro:   IPR019554 [H]

Pfam domain/function: PF01512 Complex1_51K; PF10589 NADH_4Fe-4S; PF10531 SLBB [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 50387; Mature: 50256

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSSNTPDTAAQNVLAQFAATGVQTCFHGRHIAPQILADLDGSNWRLKDYEARGGYQAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCCCHHHHH
RKILGKDGGEGLTPDQVIAEVKASSLRGRGGAGFPTGLKWSFMPRQFPGQKYLVCNSDEG
HHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCC
EPGTCKDRDIMQYNPHSVIEGMAIAAYAMGISIGYNYIHGEIFATYRRFEEALDEARAAG
CCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LIGEKILGSSFTFQLHASHGFGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPT
HHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
TINNTETFAAVPWIIRNGGQAYLECGKPNNGGTKIYSVSGDVELPGNYEVPMGTPFARLL
CCCCCCCCEECCHHEECCCEEEEECCCCCCCCCEEEEECCCEECCCCCCCCCCCHHHHHH
ELAGGVRKGRTLKAVIPGGSSAPVLPASIMMDCTMDYDSIAKAGSMLGSGAVIVMDDSRC
HHHCCCCCCCEEEEEECCCCCCCCCHHHHHEECCCCHHHHHHHHHHHCCCEEEEEECCHH
MVESLKRLSYFYMHESCGQCTPCREGTGWLWRVVDRIHNGHGKQTDMDLLNSVADNIQGR
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
TICALGDAAAMPVRAMIKHFRHEFEAMIPQKTPQPAASHIPAQAAQA
EEEEECCHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHCCC
>Mature Secondary Structure 
TLSSNTPDTAAQNVLAQFAATGVQTCFHGRHIAPQILADLDGSNWRLKDYEARGGYQAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCCCHHHHH
RKILGKDGGEGLTPDQVIAEVKASSLRGRGGAGFPTGLKWSFMPRQFPGQKYLVCNSDEG
HHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCC
EPGTCKDRDIMQYNPHSVIEGMAIAAYAMGISIGYNYIHGEIFATYRRFEEALDEARAAG
CCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LIGEKILGSSFTFQLHASHGFGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPT
HHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
TINNTETFAAVPWIIRNGGQAYLECGKPNNGGTKIYSVSGDVELPGNYEVPMGTPFARLL
CCCCCCCCEECCHHEECCCEEEEECCCCCCCCCEEEEECCCEECCCCCCCCCCCHHHHHH
ELAGGVRKGRTLKAVIPGGSSAPVLPASIMMDCTMDYDSIAKAGSMLGSGAVIVMDDSRC
HHHCCCCCCCEEEEEECCCCCCCCCHHHHHEECCCCHHHHHHHHHHHCCCEEEEEECCHH
MVESLKRLSYFYMHESCGQCTPCREGTGWLWRVVDRIHNGHGKQTDMDLLNSVADNIQGR
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
TICALGDAAAMPVRAMIKHFRHEFEAMIPQKTPQPAASHIPAQAAQA
EEEEECCHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]