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The map label for this gene is ribH

Identifier: 91788747

GI number: 91788747

Start: 3046970

End: 3047434

Strand: Direct

Name: ribH

Synonym: Bpro_2886

Alternate gene names: 91788747

Gene position: 3046970-3047434 (Clockwise)

Preceding gene: 91788746

Following gene: 91788748

Centisome position: 58.59

GC content: 57.85

Gene sequence:

>465_bases
GTGTTTGGTGCAGAAAAAGGTTCAACCGACAAGCTTGACGGCCGGAAATTTTCCATTGGCATTGTGCAGGCGCGCTTCAA
TGAAAGCGTTACCAACGCCCTCGCCGAAGCCTGCAAACAGGAGCTTGCAGCCTTGGGCGTGGAAGAAAAAAACATCAAGC
ATGTCAAGGTGCCCGGCGCGCTCGAAGTGCCTTGCGCACTGCAGGCCATGGCCGAAAGTGACAAGTACGATGCCCTGATC
GCCCTGGGCTGCATCATTCGCGGTGAGACCTATCACTTTGAGCTGGTGGCCAACGAAAGCGGCTCGGCCGTGACACGCCT
GGCGCTGGATTACCAATTGCCGATTGCCAACGCGATTTTGACGACCGAGAACCTGGCGCAGGCCGAGGCGCGCCAGATTG
AAAAAGGGCGTGACGCGGCGCGCGTTGCCGTCGAAATGGCCAATCTGCTGGACGAGCTTGCATAA

Upstream 100 bases:

>100_bases
CCGCGCCGCATGCCCAGCATGACCGGCTATGGCCTGGAGATCGTCGGCTACATCACTCAATAATTCAATCATTCAAATAA
TTCAATCAAGGGAGTTCATT

Downstream 100 bases:

>100_bases
GCCCCTGTTTCAAAAAACCTTTATTACCAACCGGCGCTTCATGGCTGAACCCCTCAACAAACCCAAACGACCACCCCAAA
TCCGCACCGGCCTGACCGAC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MFGAEKGSTDKLDGRKFSIGIVQARFNESVTNALAEACKQELAALGVEEKNIKHVKVPGALEVPCALQAMAESDKYDALI
ALGCIIRGETYHFELVANESGSAVTRLALDYQLPIANAILTTENLAQAEARQIEKGRDAARVAVEMANLLDELA

Sequences:

>Translated_154_residues
MFGAEKGSTDKLDGRKFSIGIVQARFNESVTNALAEACKQELAALGVEEKNIKHVKVPGALEVPCALQAMAESDKYDALI
ALGCIIRGETYHFELVANESGSAVTRLALDYQLPIANAILTTENLAQAEARQIEKGRDAARVAVEMANLLDELA
>Mature_154_residues
MFGAEKGSTDKLDGRKFSIGIVQARFNESVTNALAEACKQELAALGVEEKNIKHVKVPGALEVPCALQAMAESDKYDALI
ALGCIIRGETYHFELVANESGSAVTRLALDYQLPIANAILTTENLAQAEARQIEKGRDAARVAVEMANLLDELA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=137, Percent_Identity=43.0656934306569, Blast_Score=102, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324429, Length=155, Percent_Identity=32.258064516129, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_POLSJ (Q129J1)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_549699.1
- ProteinModelPortal:   Q129J1
- SMR:   Q129J1
- STRING:   Q129J1
- GeneID:   4014461
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_2886
- NMPDR:   fig|296591.1.peg.5476
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- PhylomeDB:   Q129J1
- ProtClustDB:   PRK00061
- BioCyc:   PSP296591:BPRO_2886-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16532; Mature: 16532

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGAEKGSTDKLDGRKFSIGIVQARFNESVTNALAEACKQELAALGVEEKNIKHVKVPGA
CCCCCCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
LEVPCALQAMAESDKYDALIALGCIIRGETYHFELVANESGSAVTRLALDYQLPIANAIL
CCCCHHHHHHHCCCCHHHHHHHHHEEECCEEEEEEEECCCCCEEEEEEEEECCCHHHHHH
TTENLAQAEARQIEKGRDAARVAVEMANLLDELA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFGAEKGSTDKLDGRKFSIGIVQARFNESVTNALAEACKQELAALGVEEKNIKHVKVPGA
CCCCCCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
LEVPCALQAMAESDKYDALIALGCIIRGETYHFELVANESGSAVTRLALDYQLPIANAIL
CCCCHHHHHHHCCCCHHHHHHHHHEEECCEEEEEEEECCCCCEEEEEEEEECCCHHHHHH
TTENLAQAEARQIEKGRDAARVAVEMANLLDELA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA