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The map label for this gene is lysN [H]

Identifier: 91788608

GI number: 91788608

Start: 2887411

End: 2888604

Strand: Reverse

Name: lysN [H]

Synonym: Bpro_2746

Alternate gene names: 91788608

Gene position: 2888604-2887411 (Counterclockwise)

Preceding gene: 91788610

Following gene: 91788607

Centisome position: 55.55

GC content: 62.56

Gene sequence:

>1194_bases
ATGCCGCTTCAATTTGCCGACCGCCTTAACAACGTCGAAACCTCCGCCATCCGCGAGCTTTTCAAGCTGCTGGGCAAGCC
CGGCATCATCAGCTTTGCCGGCGGCTTTCCCGACCCTGCCATGTTTGATGTGGAGGGCCTCAAGGAAGCCAGCGGCAATG
TGCTGAACGAAGAAGCCGGCCCGGCCCTGCAATACGGCGCCACCGAAGGCTACCAGCCGCTGCGCGACCAGCTCAGCACC
TTCATGGCCACCAAGGGCTCCCTGGTGGCTGCCGACCAGCTGATCGTGACCACCGGCAGCCAGCAGGCGCTGGACCTGAT
CGGCAAAACCATGATCTCGCCCGGCGACAAGGTGATCGTGGAAGGCCCCACCTTTCTGGCCACCATCCAGTGCTTCAGGC
TCTACGGCGCAGAACTCATCAGCGCACCCATCGACGCCCACGGCGTGAAGACAGACGAGCTGGAAAAATTGATCGCCCAG
CACAAGCCGAAGTTTGTGTACCTGATTCCCACTTTCGGCAACCCCAGCGGCGCCCTGTTGAGCCTGGAGCGCCGCAAGAA
GGTGCTGGAGCTGGCCGTCAAATACAACACGCTGATGGTTGAAGACGACCCCTACGGCGACCTGTATTTTTCCGAGCCAC
CACCACCGTCTTTATTGGCCTTGAGCGACACCGTGCCCGGCAGCCGCGACCTGCTGGCGCATTGCGGCTCGCTCAGCAAA
GTGCTGTCACCCGGCCTGCGCATTGGCTGGCTGATTGCCCAGCCCGAGCTGCTGGCCAAAGCCACCATGTGCAAGCAGTT
CAGTGACGCCCACACCAGCACCTTTGCCCAGGCCACGGCGTCCCAATACCTCAAATGCGGCCGCATGCCTTCCACATTGA
CCCGTGTGCGCCAGGTGTATGCCGAGCGCGCCGCGGCCATGGGCGCTGCACTGAAGCGCGAACTGGGCGACGCGATCGAT
TTTGTACAGCCGCAAGGCGGCCTGTTCTTCTGGGCCCGCCTCACGGGTGCCGGCGGCAAGACGAAAGATGCCGGCGAGTT
TGCGAAGAAGGCGATTGAGCAGGGCGTGGCCTTTGTGCCGGGCGCGCCGTTTTATGCGAGCAATCCGGATGTCTCCACAT
TGAGGCTCAGCTTTGCCACGGCGGATGTGGCGAAGATTGAGGAAGGCGTGGGGCGCTTGGGCAAGGCGCTTTAG

Upstream 100 bases:

>100_bases
ACGCTCGTATACTTCAATTCAGTAACGGGCTGTGGGTTGGCTGCTCGCAAGGTGGCAAAAAACGGCTCGATGTGTTCCTT
CTTCATGGATCGATTCTCCC

Downstream 100 bases:

>100_bases
CTGGATGCGCTGGTGATTTTGAATCGGTTTTGAGAGTTGTGGTTCGATCCACCGCATGGGGACTGTATCAGCGCCTATCA
AGAGTACAAGATCGGACGGT

Product: class I/II aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPLQFADRLNNVETSAIRELFKLLGKPGIISFAGGFPDPAMFDVEGLKEASGNVLNEEAGPALQYGATEGYQPLRDQLST
FMATKGSLVAADQLIVTTGSQQALDLIGKTMISPGDKVIVEGPTFLATIQCFRLYGAELISAPIDAHGVKTDELEKLIAQ
HKPKFVYLIPTFGNPSGALLSLERRKKVLELAVKYNTLMVEDDPYGDLYFSEPPPPSLLALSDTVPGSRDLLAHCGSLSK
VLSPGLRIGWLIAQPELLAKATMCKQFSDAHTSTFAQATASQYLKCGRMPSTLTRVRQVYAERAAAMGAALKRELGDAID
FVQPQGGLFFWARLTGAGGKTKDAGEFAKKAIEQGVAFVPGAPFYASNPDVSTLRLSFATADVAKIEEGVGRLGKAL

Sequences:

>Translated_397_residues
MPLQFADRLNNVETSAIRELFKLLGKPGIISFAGGFPDPAMFDVEGLKEASGNVLNEEAGPALQYGATEGYQPLRDQLST
FMATKGSLVAADQLIVTTGSQQALDLIGKTMISPGDKVIVEGPTFLATIQCFRLYGAELISAPIDAHGVKTDELEKLIAQ
HKPKFVYLIPTFGNPSGALLSLERRKKVLELAVKYNTLMVEDDPYGDLYFSEPPPPSLLALSDTVPGSRDLLAHCGSLSK
VLSPGLRIGWLIAQPELLAKATMCKQFSDAHTSTFAQATASQYLKCGRMPSTLTRVRQVYAERAAAMGAALKRELGDAID
FVQPQGGLFFWARLTGAGGKTKDAGEFAKKAIEQGVAFVPGAPFYASNPDVSTLRLSFATADVAKIEEGVGRLGKAL
>Mature_396_residues
PLQFADRLNNVETSAIRELFKLLGKPGIISFAGGFPDPAMFDVEGLKEASGNVLNEEAGPALQYGATEGYQPLRDQLSTF
MATKGSLVAADQLIVTTGSQQALDLIGKTMISPGDKVIVEGPTFLATIQCFRLYGAELISAPIDAHGVKTDELEKLIAQH
KPKFVYLIPTFGNPSGALLSLERRKKVLELAVKYNTLMVEDDPYGDLYFSEPPPPSLLALSDTVPGSRDLLAHCGSLSKV
LSPGLRIGWLIAQPELLAKATMCKQFSDAHTSTFAQATASQYLKCGRMPSTLTRVRQVYAERAAAMGAALKRELGDAIDF
VQPQGGLFFWARLTGAGGKTKDAGEFAKKAIEQGVAFVPGAPFYASNPDVSTLRLSFATADVAKIEEGVGRLGKAL

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=409, Percent_Identity=31.0513447432763, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI33469970, Length=409, Percent_Identity=31.0513447432763, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI4507369, Length=203, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787710, Length=370, Percent_Identity=28.3783783783784, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1790797, Length=371, Percent_Identity=27.2237196765499, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788722, Length=309, Percent_Identity=28.1553398058252, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=270, Percent_Identity=28.8888888888889, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=480, Percent_Identity=25.4166666666667, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321000, Length=428, Percent_Identity=25.7009345794392, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6321929, Length=294, Percent_Identity=23.469387755102, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356535, Length=400, Percent_Identity=27.75, Blast_Score=131, Evalue=6e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 42502; Mature: 42371

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLQFADRLNNVETSAIRELFKLLGKPGIISFAGGFPDPAMFDVEGLKEASGNVLNEEAG
CCCCHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEECHHHHHHHCCCCCCCCCC
PALQYGATEGYQPLRDQLSTFMATKGSLVAADQLIVTTGSQQALDLIGKTMISPGDKVIV
CCEECCCCCCCHHHHHHHHHHHHCCCCEEEECEEEEECCCHHHHHHHHHHHCCCCCEEEE
EGPTFLATIQCFRLYGAELISAPIDAHGVKTDELEKLIAQHKPKFVYLIPTFGNPSGALL
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEE
SLERRKKVLELAVKYNTLMVEDDPYGDLYFSEPPPPSLLALSDTVPGSRDLLAHCGSLSK
EHHHHHHHHHHHHHHCEEEECCCCCCCCEECCCCCCCEEEECCCCCCHHHHHHHHHHHHH
VLSPGLRIGWLIAQPELLAKATMCKQFSDAHTSTFAQATASQYLKCGRMPSTLTRVRQVY
HHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AERAAAMGAALKRELGDAIDFVQPQGGLFFWARLTGAGGKTKDAGEFAKKAIEQGVAFVP
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCEECC
GAPFYASNPDVSTLRLSFATADVAKIEEGVGRLGKAL
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLQFADRLNNVETSAIRELFKLLGKPGIISFAGGFPDPAMFDVEGLKEASGNVLNEEAG
CCCHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEECHHHHHHHCCCCCCCCCC
PALQYGATEGYQPLRDQLSTFMATKGSLVAADQLIVTTGSQQALDLIGKTMISPGDKVIV
CCEECCCCCCCHHHHHHHHHHHHCCCCEEEECEEEEECCCHHHHHHHHHHHCCCCCEEEE
EGPTFLATIQCFRLYGAELISAPIDAHGVKTDELEKLIAQHKPKFVYLIPTFGNPSGALL
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEE
SLERRKKVLELAVKYNTLMVEDDPYGDLYFSEPPPPSLLALSDTVPGSRDLLAHCGSLSK
EHHHHHHHHHHHHHHCEEEECCCCCCCCEECCCCCCCEEEECCCCCCHHHHHHHHHHHHH
VLSPGLRIGWLIAQPELLAKATMCKQFSDAHTSTFAQATASQYLKCGRMPSTLTRVRQVY
HHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AERAAAMGAALKRELGDAIDFVQPQGGLFFWARLTGAGGKTKDAGEFAKKAIEQGVAFVP
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCEECC
GAPFYASNPDVSTLRLSFATADVAKIEEGVGRLGKAL
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA