Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 91788575

GI number: 91788575

Start: 2858496

End: 2859233

Strand: Direct

Name: ompR [H]

Synonym: Bpro_2713

Alternate gene names: 91788575

Gene position: 2858496-2859233 (Clockwise)

Preceding gene: 91788573

Following gene: 91788576

Centisome position: 54.97

GC content: 62.47

Gene sequence:

>738_bases
ATGACCCAAGCTCAACCCACTGCCCGTGCCGACAAGATTCTCATCCTTGACGACGACGCCCGCATTCGCGACCTGTTGCG
CCGCTACCTGGCCCAAGAGGGCTTCGAAGTCATTCTTGCCGAAGACAGCAAGGCCCTGAACCGCATCATGCTGCGTGACG
CTGTCGACCTGATCGTGCTGGACCTGATGATGCCCGGTGAAGACGGCCTTTCCATTTGCCGCCGCCTGCGCGCCGCCAAC
GATCGCACCCCCATCATCATGCTGACCGCCAAAGGTGAAGACGTGGACCGCATCGTCGGCCTGGAAGTTGGCGCCGACGA
CTACCTGGCCAAACCCTTCAATCCCCGGGAACTGCTGGCCCGCATCCACGCGGTGCTGCGCCGCCGCCCCACAGCCGAAG
TGCCGGGCGCGCCGTCCAGCGACCAGGAAGTGATTACTTTCGGGCCGTTTTCCTTCGACATGGGCCTGCGCACACTGCAT
AAAAATGGCGAAGAACTGCCGCTGACCACTGGCGAGTTCGCCATGCTGAAAACCCTGGTGCGCCATCCTCGCCAGCCGCT
TTCCCGCGAAAAGCTGGCGCAACTGGCGCGCGGCCGCGAGTTCGAACCTTTCGACCGCAGCCTGGACGTGCAGGTCTCGC
GCCTGCGCAAGCTGATCGAGGTGGATGCAGCCGTTCCCCGCTACATACAGACAGTCTGGGGTATCGGCTACGTTTTTGTA
CCGGATGGAACCAACTGA

Upstream 100 bases:

>100_bases
TCGCCGCAACTTTTGTAACAGTGTGTCAAAGCGAGTGAAAAAAGAGACATCGGGCGTTTTCAGCCTTCAAAATGGCTCTG
TTACAAATTACCGGATGACT

Downstream 100 bases:

>100_bases
CACACCAGGTCTCACCCACCTCACGTCTTGCAGGAGGTGCCAGCCGTCCACGCTGACCTGACCGGCACCCGGCGAGACTC
ACGTCCATCCTTGCGCCCTT

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTQAQPTARADKILILDDDARIRDLLRRYLAQEGFEVILAEDSKALNRIMLRDAVDLIVLDLMMPGEDGLSICRRLRAAN
DRTPIIMLTAKGEDVDRIVGLEVGADDYLAKPFNPRELLARIHAVLRRRPTAEVPGAPSSDQEVITFGPFSFDMGLRTLH
KNGEELPLTTGEFAMLKTLVRHPRQPLSREKLAQLARGREFEPFDRSLDVQVSRLRKLIEVDAAVPRYIQTVWGIGYVFV
PDGTN

Sequences:

>Translated_245_residues
MTQAQPTARADKILILDDDARIRDLLRRYLAQEGFEVILAEDSKALNRIMLRDAVDLIVLDLMMPGEDGLSICRRLRAAN
DRTPIIMLTAKGEDVDRIVGLEVGADDYLAKPFNPRELLARIHAVLRRRPTAEVPGAPSSDQEVITFGPFSFDMGLRTLH
KNGEELPLTTGEFAMLKTLVRHPRQPLSREKLAQLARGREFEPFDRSLDVQVSRLRKLIEVDAAVPRYIQTVWGIGYVFV
PDGTN
>Mature_244_residues
TQAQPTARADKILILDDDARIRDLLRRYLAQEGFEVILAEDSKALNRIMLRDAVDLIVLDLMMPGEDGLSICRRLRAAND
RTPIIMLTAKGEDVDRIVGLEVGADDYLAKPFNPRELLARIHAVLRRRPTAEVPGAPSSDQEVITFGPFSFDMGLRTLHK
NGEELPLTTGEFAMLKTLVRHPRQPLSREKLAQLARGREFEPFDRSLDVQVSRLRKLIEVDAAVPRYIQTVWGIGYVFVP
DGTN

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=61.965811965812, Blast_Score=310, Evalue=6e-86,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=38.2978723404255, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=38.3620689655172, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1788394, Length=245, Percent_Identity=35.9183673469388, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=34.1991341991342, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.7682403433476, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=35.3448275862069, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=35.3191489361702, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=35.6521739130435, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=33.4801762114537, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=35.3448275862069, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=35.4700854700855, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=134, Percent_Identity=26.865671641791, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27612; Mature: 27481

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAQPTARADKILILDDDARIRDLLRRYLAQEGFEVILAEDSKALNRIMLRDAVDLIVL
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHH
DLMMPGEDGLSICRRLRAANDRTPIIMLTAKGEDVDRIVGLEVGADDYLAKPFNPRELLA
HHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEEEECCCHHHCCCCCHHHHHH
RIHAVLRRRPTAEVPGAPSSDQEVITFGPFSFDMGLRTLHKNGEELPLTTGEFAMLKTLV
HHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
RHPRQPLSREKLAQLARGREFEPFDRSLDVQVSRLRKLIEVDAAVPRYIQTVWGIGYVFV
HCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
PDGTN
CCCCC
>Mature Secondary Structure 
TQAQPTARADKILILDDDARIRDLLRRYLAQEGFEVILAEDSKALNRIMLRDAVDLIVL
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHH
DLMMPGEDGLSICRRLRAANDRTPIIMLTAKGEDVDRIVGLEVGADDYLAKPFNPRELLA
HHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEEEECCCHHHCCCCCHHHHHH
RIHAVLRRRPTAEVPGAPSSDQEVITFGPFSFDMGLRTLHKNGEELPLTTGEFAMLKTLV
HHHHHHHCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
RHPRQPLSREKLAQLARGREFEPFDRSLDVQVSRLRKLIEVDAAVPRYIQTVWGIGYVFV
HCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
PDGTN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]