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The map label for this gene is ybdL [H]

Identifier: 91788268

GI number: 91788268

Start: 2501423

End: 2502598

Strand: Reverse

Name: ybdL [H]

Synonym: Bpro_2403

Alternate gene names: 91788268

Gene position: 2502598-2501423 (Counterclockwise)

Preceding gene: 91788269

Following gene: 91788267

Centisome position: 48.12

GC content: 61.56

Gene sequence:

>1176_bases
ATGACCACTATCCTCGAACGCACCCCCAAACTGGAAACCAAGCTGCCCGCCGTCGGCACCACGATCTTCACGGTGATGTC
CACCCTGGCGGCCGAAAAAGGCGCCGTCAACCTCGGCCAGGGCTTTCCCGACTTTGAATGCGACCCGCAGCTGGTCAATG
CCGTCACGGACGCCATGACAAAAGGCTTGAACCAGTATCCGCCCATGACGGGCGTTCCGGTGCTGCGCGAGGCCATCTCC
GCCAAAGTGGCCAAACTGTATGGCCATCGCTACAACGCCAACACCGAGATCACCATCACCGCCGGTGCCACACAAGCCAT
CATCACGGTCATTCTGGCCGTGGTGCACCCCGGCGATGAAGTGATCGTGCTGGAACCCTGCTACGACAGCTATGTGCCCA
ATATCGAGCTGGCCGGCGGCAAGGTGGTGCGCGTGCCTTTGACGCCCGGCACCTTCCGCCCCGACTTTGACAAGATTGCG
GCGGCCATCACGCCCCAAACCCGCGCCATCATCATCAACTCGCCGCACAACCCGAGTGCCACGGTCTGGACGCAGGCCGA
CATGCTCAAGCTGCAAGACATCCTCGCCCCCACCGACGTGCTGCTGATCAGCGACGAGGTCTATGAGCACATGGTGTTTG
ACGCGGCCAAAGGTTGCATGCACCAAAGCGCCAGCCTGTTTCCGGGCCTGGCGGCACGCGCCTTCATCGTCAGCAGCTTC
GGCAAAACCTACCATGTGACCGGCTGGAAGGTCGGCTACGTTGCAGCGCCTGCCGCTTTGACCGCCGAGTTCCGCAAGGT
GCACCAGTTCAATGTGTTCACTGTCAACACGCCCGTGCAGTACGGCCTAGCCGCCTACATGGCCGACCCCAAGCCTTACC
TGGACCTGCCTGCGTTCTACGAGCGCAAGCGCGACCTCTTTCGCGCCGGGCTGGCCAAAACCCGCTTCAAGCTGCTGCCC
AGCGAAGGCACGTATTTCCAGTGCGTGGACATTTCAGAGGTCAGCGACCTCAACGAAGCTGACTTTTGCCAATGGCTCAC
CACCGAGATCGGCGTGGCTGCGATTCCGCTGTCGGCCTTCTACGGCAACGGGTTCGATCAGCGCGTGGTGCGCTTTTGCT
TTGCGAAGAAGGATGAGACGCTGCACTCGGCATTGGGGCGGCTGGCGAAGTTGTGA

Upstream 100 bases:

>100_bases
GAACCGACCTGCGGCCGTTTCCCCCTCAAGGGGGCGCCGCTAGCGGCCCGGCGAAGCCGGTTCCGCGGCGGCCGCTTGAA
AAAACCCTCACTTTGCAGAC

Downstream 100 bases:

>100_bases
GCAAAGGGCCAACCCGAACGGAGATGCCGGCCCTTAAACATCATGTGAAAGAGCGGCCGGCGTATTCGGAAACTTGCTCA
CTTGCCAGACCGCTTCGGAA

Product: putative aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTTILERTPKLETKLPAVGTTIFTVMSTLAAEKGAVNLGQGFPDFECDPQLVNAVTDAMTKGLNQYPPMTGVPVLREAIS
AKVAKLYGHRYNANTEITITAGATQAIITVILAVVHPGDEVIVLEPCYDSYVPNIELAGGKVVRVPLTPGTFRPDFDKIA
AAITPQTRAIIINSPHNPSATVWTQADMLKLQDILAPTDVLLISDEVYEHMVFDAAKGCMHQSASLFPGLAARAFIVSSF
GKTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPVQYGLAAYMADPKPYLDLPAFYERKRDLFRAGLAKTRFKLLP
SEGTYFQCVDISEVSDLNEADFCQWLTTEIGVAAIPLSAFYGNGFDQRVVRFCFAKKDETLHSALGRLAKL

Sequences:

>Translated_391_residues
MTTILERTPKLETKLPAVGTTIFTVMSTLAAEKGAVNLGQGFPDFECDPQLVNAVTDAMTKGLNQYPPMTGVPVLREAIS
AKVAKLYGHRYNANTEITITAGATQAIITVILAVVHPGDEVIVLEPCYDSYVPNIELAGGKVVRVPLTPGTFRPDFDKIA
AAITPQTRAIIINSPHNPSATVWTQADMLKLQDILAPTDVLLISDEVYEHMVFDAAKGCMHQSASLFPGLAARAFIVSSF
GKTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPVQYGLAAYMADPKPYLDLPAFYERKRDLFRAGLAKTRFKLLP
SEGTYFQCVDISEVSDLNEADFCQWLTTEIGVAAIPLSAFYGNGFDQRVVRFCFAKKDETLHSALGRLAKL
>Mature_390_residues
TTILERTPKLETKLPAVGTTIFTVMSTLAAEKGAVNLGQGFPDFECDPQLVNAVTDAMTKGLNQYPPMTGVPVLREAISA
KVAKLYGHRYNANTEITITAGATQAIITVILAVVHPGDEVIVLEPCYDSYVPNIELAGGKVVRVPLTPGTFRPDFDKIAA
AITPQTRAIIINSPHNPSATVWTQADMLKLQDILAPTDVLLISDEVYEHMVFDAAKGCMHQSASLFPGLAARAFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPVQYGLAAYMADPKPYLDLPAFYERKRDLFRAGLAKTRFKLLPS
EGTYFQCVDISEVSDLNEADFCQWLTTEIGVAAIPLSAFYGNGFDQRVVRFCFAKKDETLHSALGRLAKL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=402, Percent_Identity=33.5820895522388, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI56713256, Length=402, Percent_Identity=33.5820895522388, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI95147551, Length=413, Percent_Identity=31.9612590799031, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI169881279, Length=413, Percent_Identity=31.9612590799031, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI169881281, Length=411, Percent_Identity=28.7104622871046, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI4507369, Length=220, Percent_Identity=27.7272727272727, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786816, Length=381, Percent_Identity=52.49343832021, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=24.2105263157895, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788627, Length=256, Percent_Identity=27.734375, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787710, Length=390, Percent_Identity=25.3846153846154, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=423, Percent_Identity=33.5697399527187, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71994476, Length=423, Percent_Identity=33.5697399527187, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17567369, Length=403, Percent_Identity=31.2655086848635, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=394, Percent_Identity=34.010152284264, Blast_Score=192, Evalue=9e-50,
Organism=Drosophila melanogaster, GI28573069, Length=413, Percent_Identity=32.2033898305085, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI24646114, Length=413, Percent_Identity=32.2033898305085, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI28573067, Length=413, Percent_Identity=32.2033898305085, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI28573065, Length=413, Percent_Identity=32.2033898305085, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI18859735, Length=225, Percent_Identity=28, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42702; Mature: 42570

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTILERTPKLETKLPAVGTTIFTVMSTLAAEKGAVNLGQGFPDFECDPQLVNAVTDAMT
CCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KGLNQYPPMTGVPVLREAISAKVAKLYGHRYNANTEITITAGATQAIITVILAVVHPGDE
HCHHHCCCCCCHHHHHHHHHHHHHHHHCCEECCCCEEEEECCCHHHHHHHHHHHCCCCCC
VIVLEPCYDSYVPNIELAGGKVVRVPLTPGTFRPDFDKIAAAITPQTRAIIINSPHNPSA
EEEEECCHHCCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCE
TVWTQADMLKLQDILAPTDVLLISDEVYEHMVFDAAKGCMHQSASLFPGLAARAFIVSSF
EEEEHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHC
GKTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPVQYGLAAYMADPKPYLDLPAFY
CCEEEECCEEEEEEECCHHHHHHHHHHHEEEEEEECCCHHHHHHHHCCCCCCCCCCCHHH
ERKRDLFRAGLAKTRFKLLPSEGTYFQCVDISEVSDLNEADFCQWLTTEIGVAAIPLSAF
HHHHHHHHHHHHHHHEEEECCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCHHEEEHHHH
YGNGFDQRVVRFCFAKKDETLHSALGRLAKL
HCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TTILERTPKLETKLPAVGTTIFTVMSTLAAEKGAVNLGQGFPDFECDPQLVNAVTDAMT
CCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KGLNQYPPMTGVPVLREAISAKVAKLYGHRYNANTEITITAGATQAIITVILAVVHPGDE
HCHHHCCCCCCHHHHHHHHHHHHHHHHCCEECCCCEEEEECCCHHHHHHHHHHHCCCCCC
VIVLEPCYDSYVPNIELAGGKVVRVPLTPGTFRPDFDKIAAAITPQTRAIIINSPHNPSA
EEEEECCHHCCCCCEEECCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCE
TVWTQADMLKLQDILAPTDVLLISDEVYEHMVFDAAKGCMHQSASLFPGLAARAFIVSSF
EEEEHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHC
GKTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPVQYGLAAYMADPKPYLDLPAFY
CCEEEECCEEEEEEECCHHHHHHHHHHHEEEEEEECCCHHHHHHHHCCCCCCCCCCCHHH
ERKRDLFRAGLAKTRFKLLPSEGTYFQCVDISEVSDLNEADFCQWLTTEIGVAAIPLSAF
HHHHHHHHHHHHHHHEEEECCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCHHEEEHHHH
YGNGFDQRVVRFCFAKKDETLHSALGRLAKL
HCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]