Click here to switch to the map view.

The map label for this gene is clpB [H]

Identifier: 91788074

GI number: 91788074

Start: 2296173

End: 2298773

Strand: Direct

Name: clpB [H]

Synonym: Bpro_2201

Alternate gene names: 91788074

Gene position: 2296173-2298773 (Clockwise)

Preceding gene: 91788072

Following gene: 91788076

Centisome position: 44.15

GC content: 61.82

Gene sequence:

>2601_bases
ATGCGCCAGGACAAACTCACCACCAAATTTCAGGAAGCGCTCAGCGATGCACAGTCGCTGGCACTCGGCAACGACAACGG
CTACATCGAGCCTGCTCATTTGCTGGCGGCCATGCTGCGCCAGGATGACGGCCCCCGCGCCTTGCTGGAGCGGGCCGGCG
TCAATGTCAATGGGCTGACCCAGGCGGCCGATAGCGCCGTCAAAAAACTGCCCCAGGTGCAGGGTCAGGACCAGATCCAG
GTCGGCCCCGAGCTGGCCCGGTTGCTGCAGGCCACCGAAAAAGAAGCGATCAAGCGCAATGACCAGTTCATTGCCGGTGA
GCTTTTTTTGCTGGCCGTGGCCGACAGCAAGGCCGACGTGGGCAGGATCGCTCGCGAAAACGGCCTGACCCGCAAGTCGC
TGGAAGCGGCGATTGACGCGGTACGCGGCGGGCAGGGCGTGAACAGCGCTGATGCGGAGGGCCAACGCGAAGCCCTGAAG
AAATACTGCATGGACCTGACAGAGCGCGCACGCCTGGGCAAGCTCGATCCGGTGATTGGGCGCGACGATGAAATCCGGCG
TGCCATCCAGGTGCTGCAGCGCCGCACCAAAAACAACCCGGTGCTGATTGGTGAGCCCGGCGTCGGCAAGACCGCCATCG
TCGAGGGCCTGGCCCAGCGCATCGTGGCTGGCGAGGTACCCGATTCATTGAAGGGCAAGCGCGTGCTGTCACTCGACATG
GCCGCCTTGCTGGCCGGGGCCAAATTCCGTGGCGAGTTTGAAGAGCGCCTGAAAACCGTGCTCAATGAATTGGCCAAGGA
TGAAGGCCAGACCATCGTCTTTATCGACGAGCTGCACACCATGGTCGGCGCCGGCAAGGCAGAAGGCGCCATGGATGCCG
GCAACATGCTCAAGCCCGCGCTGGCGCGTGGCGAGCTGCACTGCGTGGGTGCCACCACCCTGGACGAATACCGCAAGTAC
ATTGAAAAGGACGCCGCCCTGGAGCGTCGCTTCCAGAAGATACTGGTGGACGAGCCCACGGTGGAAGCCACCATTGCCAT
CCTGCGCGGGCTGCAGGAAAAATACGAAGTCCACCATGGTGTGCAGATCACCGACCCGGCCATCGTGGCTGCGGCCGAAC
TCAGCCACCGCTACATCACCGACCGCTTTTTGCCCGACAAGGCCATCGACCTGATTGACGAGGCAGCGGCCAAGATCAAG
ATCGAGATGGACTCCAAGCCCGAGGTGATGGATCGCCTTGACCGGCGCCTGATCCAGCTGCAGATCGAGCGTGAAGCCGT
GCGCCGCGAAAAAGACGAAGCGTCGCAAAAGCGCTTTGGATTGATCGAAGTGGAGATCGCCAAGCTGCAGAAGGAGATAT
CCGATCTCGACGAAATCTGGCAGGCCGAAAAAGCCCAGGCGCTCGGCTCCAAGGACGTCATGGAAGAGATCGACCGCATC
CGCTTCCAGATTGAAGAGTTCACCCGCAAGGGCGACTTCAACAAGGTTGCCGAGCTGCAATACGGCAAGCTGCCCGAACT
TGAAAAACGCCTCAAGGCCGCGCAGGACACCGAGGCGCAGAAGGAAACCAGCGATGTGCCCAAGCTGCTGCGTACCCAGG
TCGGCGCCGAAGAGATTGCCGAGGTTGTCGCGCGTGCCACCGGTATTCCGGTCAGCAAGCTGATGCAGGGCGAGCGCGAC
AAGCTGCTGCTGATGGAGGGAAAACTGCATGAGCGCGTGGTCGGCCAGGACGAGGCCATAGGCGCAGTCGCCAACGCGAT
CCGCCGTTCGCGTTCGGGTCTCAGCGATCCGAATCGGCCGACCGGCTCCTTCCTGTTCCTTGGCCCGACGGGTGTGGGAA
AGACCGAGCTGTGCAAGGCGCTGGCAGGCTTCCTGTTTGACAGTGAAGACCACCTGATCCGCGTTGACATGAGCGAGTTC
ATGGAGAAGCACTCGGTCGCCCGCCTGATTGGGGCGCCTCCCGGCTATGTGGGTTACGAGGAGGGCGGTCATCTCACCGA
GGCCGTGCGCCGCAAACCCTACAGCGTGCTGCTGCTCGACGAGATTGAAAAGGCTCACCCCGATGTGTTCAACGTACTGT
TGCAGGTGCTTGACGATGGGCGCCTGACCGACGGCCAGGGCCGCACCGTGGACTTTAAAAACACCGTGATCGTGATGACC
AGCAACATCGGTTCACCCATTATCCAGTCCATGGTTGGCCAGCCGGCCGAAGACATCAAGGACGCGGTGACCGACGAGCT
GAAGAACTACTTCCGCCCGGAGTTCCTGAATCGCATTGACGAGACCGTGGTGTTTCATGCGCTCGACGCGAAGAACATCG
AGTCGATCGCGCGTATCCAGCTCAAGGTGTTGATGGAGCGCCTGCAGAAAATGGACCTGGCGATGGAAGTCTCGGAGGCG
GCAATTGCCGAGCTGGCCAAGGTCGGCTTCGACCCGGTGTTTGGCGCACGGCCACTCAAGCGCGCCATCCAGCAGCGCAT
CGAAAATCCGCTGTCCAGGCTGTTGCTGGAAGGGCGCTTTCCGCCCAAGAGCGTGATCCCGGTCGAGGTGGATCCCGTGC
GCGAGCCGGGCGTTTTCAAGTTCGAGCGAGCCGCCCACTAG

Upstream 100 bases:

>100_bases
CTCGGGGTAGCCGCTGGCCAGACCCGCCGGTTGTCGGCGCTATTGAAAAAGCTTTGGTCCAGCCCCAGATCAACAGCAAT
CAAATTCGAAGGGACGCCTC

Downstream 100 bases:

>100_bases
GCCCTGGTGCCCCAGGGTGCCATGGAGTTTGTAGCTTCCGGCGATCGCCATTTTCAATGGCTACGCATGTTTTGTCGCTG
AGGATAAAACCCGATCCTGC

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 866; Mature: 866

Protein sequence:

>866_residues
MRQDKLTTKFQEALSDAQSLALGNDNGYIEPAHLLAAMLRQDDGPRALLERAGVNVNGLTQAADSAVKKLPQVQGQDQIQ
VGPELARLLQATEKEAIKRNDQFIAGELFLLAVADSKADVGRIARENGLTRKSLEAAIDAVRGGQGVNSADAEGQREALK
KYCMDLTERARLGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGEVPDSLKGKRVLSLDM
AALLAGAKFRGEFEERLKTVLNELAKDEGQTIVFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYRKY
IEKDAALERRFQKILVDEPTVEATIAILRGLQEKYEVHHGVQITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAKIK
IEMDSKPEVMDRLDRRLIQLQIEREAVRREKDEASQKRFGLIEVEIAKLQKEISDLDEIWQAEKAQALGSKDVMEEIDRI
RFQIEEFTRKGDFNKVAELQYGKLPELEKRLKAAQDTEAQKETSDVPKLLRTQVGAEEIAEVVARATGIPVSKLMQGERD
KLLLMEGKLHERVVGQDEAIGAVANAIRRSRSGLSDPNRPTGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRVDMSEF
MEKHSVARLIGAPPGYVGYEEGGHLTEAVRRKPYSVLLLDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIVMT
SNIGSPIIQSMVGQPAEDIKDAVTDELKNYFRPEFLNRIDETVVFHALDAKNIESIARIQLKVLMERLQKMDLAMEVSEA
AIAELAKVGFDPVFGARPLKRAIQQRIENPLSRLLLEGRFPPKSVIPVEVDPVREPGVFKFERAAH

Sequences:

>Translated_866_residues
MRQDKLTTKFQEALSDAQSLALGNDNGYIEPAHLLAAMLRQDDGPRALLERAGVNVNGLTQAADSAVKKLPQVQGQDQIQ
VGPELARLLQATEKEAIKRNDQFIAGELFLLAVADSKADVGRIARENGLTRKSLEAAIDAVRGGQGVNSADAEGQREALK
KYCMDLTERARLGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGEVPDSLKGKRVLSLDM
AALLAGAKFRGEFEERLKTVLNELAKDEGQTIVFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYRKY
IEKDAALERRFQKILVDEPTVEATIAILRGLQEKYEVHHGVQITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAKIK
IEMDSKPEVMDRLDRRLIQLQIEREAVRREKDEASQKRFGLIEVEIAKLQKEISDLDEIWQAEKAQALGSKDVMEEIDRI
RFQIEEFTRKGDFNKVAELQYGKLPELEKRLKAAQDTEAQKETSDVPKLLRTQVGAEEIAEVVARATGIPVSKLMQGERD
KLLLMEGKLHERVVGQDEAIGAVANAIRRSRSGLSDPNRPTGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRVDMSEF
MEKHSVARLIGAPPGYVGYEEGGHLTEAVRRKPYSVLLLDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIVMT
SNIGSPIIQSMVGQPAEDIKDAVTDELKNYFRPEFLNRIDETVVFHALDAKNIESIARIQLKVLMERLQKMDLAMEVSEA
AIAELAKVGFDPVFGARPLKRAIQQRIENPLSRLLLEGRFPPKSVIPVEVDPVREPGVFKFERAAH
>Mature_866_residues
MRQDKLTTKFQEALSDAQSLALGNDNGYIEPAHLLAAMLRQDDGPRALLERAGVNVNGLTQAADSAVKKLPQVQGQDQIQ
VGPELARLLQATEKEAIKRNDQFIAGELFLLAVADSKADVGRIARENGLTRKSLEAAIDAVRGGQGVNSADAEGQREALK
KYCMDLTERARLGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGEVPDSLKGKRVLSLDM
AALLAGAKFRGEFEERLKTVLNELAKDEGQTIVFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYRKY
IEKDAALERRFQKILVDEPTVEATIAILRGLQEKYEVHHGVQITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAKIK
IEMDSKPEVMDRLDRRLIQLQIEREAVRREKDEASQKRFGLIEVEIAKLQKEISDLDEIWQAEKAQALGSKDVMEEIDRI
RFQIEEFTRKGDFNKVAELQYGKLPELEKRLKAAQDTEAQKETSDVPKLLRTQVGAEEIAEVVARATGIPVSKLMQGERD
KLLLMEGKLHERVVGQDEAIGAVANAIRRSRSGLSDPNRPTGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRVDMSEF
MEKHSVARLIGAPPGYVGYEEGGHLTEAVRRKPYSVLLLDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIVMT
SNIGSPIIQSMVGQPAEDIKDAVTDELKNYFRPEFLNRIDETVVFHALDAKNIESIARIQLKVLMERLQKMDLAMEVSEA
AIAELAKVGFDPVFGARPLKRAIQQRIENPLSRLLLEGRFPPKSVIPVEVDPVREPGVFKFERAAH

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=317, Percent_Identity=35.6466876971609, Blast_Score=203, Evalue=5e-52,
Organism=Escherichia coli, GI1788943, Length=857, Percent_Identity=63.8273045507585, Blast_Score=1105, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=419, Percent_Identity=39.1408114558473, Blast_Score=276, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=691, Percent_Identity=53.2561505065123, Blast_Score=740, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=860, Percent_Identity=43.2558139534884, Blast_Score=666, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95935; Mature: 95935

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQDKLTTKFQEALSDAQSLALGNDNGYIEPAHLLAAMLRQDDGPRALLERAGVNVNGLT
CCCCHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHH
QAADSAVKKLPQVQGQDQIQVGPELARLLQATEKEAIKRNDQFIAGELFLLAVADSKADV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECEEEEEEEECCCHHH
GRIARENGLTRKSLEAAIDAVRGGQGVNSADAEGQREALKKYCMDLTERARLGKLDPVIG
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
RDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGEVPDSLKGKRVLSLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHH
AALLAGAKFRGEFEERLKTVLNELAKDEGQTIVFIDELHTMVGAGKAEGAMDAGNMLKPA
HHHHHCCHHCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHHH
LARGELHCVGATTLDEYRKYIEKDAALERRFQKILVDEPTVEATIAILRGLQEKYEVHHG
HHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
VQITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAKIKIEMDSKPEVMDRLDRRLIQL
CEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHH
QIEREAVRREKDEASQKRFGLIEVEIAKLQKEISDLDEIWQAEKAQALGSKDVMEEIDRI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RFQIEEFTRKGDFNKVAELQYGKLPELEKRLKAAQDTEAQKETSDVPKLLRTQVGAEEIA
HHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EVVARATGIPVSKLMQGERDKLLLMEGKLHERVVGQDEAIGAVANAIRRSRSGLSDPNRP
HHHHHHCCCCHHHHHCCCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
TGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRVDMSEFMEKHSVARLIGAPPGYVGYE
CCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
EGGHLTEAVRRKPYSVLLLDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIVMT
CCCHHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEE
SNIGSPIIQSMVGQPAEDIKDAVTDELKNYFRPEFLNRIDETVVFHALDAKNIESIARIQ
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LKVLMERLQKMDLAMEVSEAAIAELAKVGFDPVFGARPLKRAIQQRIENPLSRLLLEGRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PPKSVIPVEVDPVREPGVFKFERAAH
CCCCCCCEECCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MRQDKLTTKFQEALSDAQSLALGNDNGYIEPAHLLAAMLRQDDGPRALLERAGVNVNGLT
CCCCHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHH
QAADSAVKKLPQVQGQDQIQVGPELARLLQATEKEAIKRNDQFIAGELFLLAVADSKADV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECEEEEEEEECCCHHH
GRIARENGLTRKSLEAAIDAVRGGQGVNSADAEGQREALKKYCMDLTERARLGKLDPVIG
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
RDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGEVPDSLKGKRVLSLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHH
AALLAGAKFRGEFEERLKTVLNELAKDEGQTIVFIDELHTMVGAGKAEGAMDAGNMLKPA
HHHHHCCHHCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHHH
LARGELHCVGATTLDEYRKYIEKDAALERRFQKILVDEPTVEATIAILRGLQEKYEVHHG
HHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
VQITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAKIKIEMDSKPEVMDRLDRRLIQL
CEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHH
QIEREAVRREKDEASQKRFGLIEVEIAKLQKEISDLDEIWQAEKAQALGSKDVMEEIDRI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RFQIEEFTRKGDFNKVAELQYGKLPELEKRLKAAQDTEAQKETSDVPKLLRTQVGAEEIA
HHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EVVARATGIPVSKLMQGERDKLLLMEGKLHERVVGQDEAIGAVANAIRRSRSGLSDPNRP
HHHHHHCCCCHHHHHCCCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
TGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRVDMSEFMEKHSVARLIGAPPGYVGYE
CCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
EGGHLTEAVRRKPYSVLLLDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIVMT
CCCHHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEE
SNIGSPIIQSMVGQPAEDIKDAVTDELKNYFRPEFLNRIDETVVFHALDAKNIESIARIQ
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LKVLMERLQKMDLAMEVSEAAIAELAKVGFDPVFGARPLKRAIQQRIENPLSRLLLEGRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PPKSVIPVEVDPVREPGVFKFERAAH
CCCCCCCEECCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]