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The map label for this gene is siaP [H]

Identifier: 91787994

GI number: 91787994

Start: 2211886

End: 2212938

Strand: Reverse

Name: siaP [H]

Synonym: Bpro_2121

Alternate gene names: 91787994

Gene position: 2212938-2211886 (Counterclockwise)

Preceding gene: 91787995

Following gene: 91787992

Centisome position: 42.55

GC content: 60.87

Gene sequence:

>1053_bases
ATGATTCAACGCCGCACCCTTTTGAAATCCGGTGCCGCCGTGGCCCTGGGCGCACCTGCCCTGAGCGGCCTGGCCCAGCA
GGTCGTCACCCTCAAATTCCATACCTTCATGTCCCCGCAGTCCAACGTCTGGCAGTCCATGCACAAGCCCTGGATGGAAA
AAGTCGAGAAAGAGTCCGGTGGGCGCATCAAGTTTGAAGCCTACCCCGCCATGCAACTCGGCGGCACGCCGGTGCAGCTC
TATGACCAGGTCAAGGACGGCGTGGTTGACGTGGTGTGGACCCTGCCCGGCAATACCGCCGGCCGCTTCCCGCGCGTCGA
TGTCTTCGACCTGCCTTTCATGATGAGCAACGCCGAGGCCACATCCAAAGCCTACTGGGAATATGTGCAGACCGTGGCCG
TTGACGAGTTCAAGGACACCCAGGTCCTCGCGCTTCATGTGCACGGCCCCGGCGTGATTCATACCGTCAACAAGCCGGTC
AAGTCCATCAATGACATGCGCGGCCTCAAACTGCGCGCACCGACCCGCCAGGTCACCAAATTGATGGGCGTGCTGGGCGC
CATCCCCGTCGGCATGCCTTTGCCGCAAATTCCGGACGGGCTGAGCAAAGGCACCATCGAAGGCTGCGTGATTCCCTGGG
AAGTGGTGCCTTCGGTCAAGGTCCATGAGCTCACCAAATTCCATGCGGAATTTGACCCGGCCGGTGGTGCCCTGTACACC
CTGACGTTTGTGATGGCGATGAACAAGGCCAAGTACAACTCACTGCCGCCCGACCTCAAGAAAGTCATCGACAACAATTC
GGGCATGGCCACCTCGGCCTGGCTCGGCAAGGTGCAGCAGGGCAACGACGCTGCCGGCCGCAAGAGCGCCAGCGACCGCG
GCAACACCATCTACACTGTGAGTGCGGCCGAGGCGCAGGAATTCCGCCGCAAGTCGCGTGCGGTGGAAGTCGAGTGGGTG
GAAGACATGAACAAGAAAGGCTTTGACGGCAAGAAACTGCTGGACACGGCACGCAGCCTCATTGAAAAGCACACCAAGGC
CACCAAGGCCTGA

Upstream 100 bases:

>100_bases
GGTGGGCTTTATCAAGTGAAATCCGCGGGTAAGTCCTGAAAACCACCGGCCGCTTTTACCGTTAATTTCAATAACTATCC
CGATACAAGGAGACTTCATC

Downstream 100 bases:

>100_bases
CCCCCCGCCCGGTGAAGGGGACATGAGAAGAACCGGGCTGTGGCCCGGTTTTTTTTATGGTTTTTGCCGCCCAGCTTCCA
AAAAAACGGGGCAATTAGCT

Product: TRAP dicarboxylate transporter subunit DctP

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MIQRRTLLKSGAAVALGAPALSGLAQQVVTLKFHTFMSPQSNVWQSMHKPWMEKVEKESGGRIKFEAYPAMQLGGTPVQL
YDQVKDGVVDVVWTLPGNTAGRFPRVDVFDLPFMMSNAEATSKAYWEYVQTVAVDEFKDTQVLALHVHGPGVIHTVNKPV
KSINDMRGLKLRAPTRQVTKLMGVLGAIPVGMPLPQIPDGLSKGTIEGCVIPWEVVPSVKVHELTKFHAEFDPAGGALYT
LTFVMAMNKAKYNSLPPDLKKVIDNNSGMATSAWLGKVQQGNDAAGRKSASDRGNTIYTVSAAEAQEFRRKSRAVEVEWV
EDMNKKGFDGKKLLDTARSLIEKHTKATKA

Sequences:

>Translated_350_residues
MIQRRTLLKSGAAVALGAPALSGLAQQVVTLKFHTFMSPQSNVWQSMHKPWMEKVEKESGGRIKFEAYPAMQLGGTPVQL
YDQVKDGVVDVVWTLPGNTAGRFPRVDVFDLPFMMSNAEATSKAYWEYVQTVAVDEFKDTQVLALHVHGPGVIHTVNKPV
KSINDMRGLKLRAPTRQVTKLMGVLGAIPVGMPLPQIPDGLSKGTIEGCVIPWEVVPSVKVHELTKFHAEFDPAGGALYT
LTFVMAMNKAKYNSLPPDLKKVIDNNSGMATSAWLGKVQQGNDAAGRKSASDRGNTIYTVSAAEAQEFRRKSRAVEVEWV
EDMNKKGFDGKKLLDTARSLIEKHTKATKA
>Mature_350_residues
MIQRRTLLKSGAAVALGAPALSGLAQQVVTLKFHTFMSPQSNVWQSMHKPWMEKVEKESGGRIKFEAYPAMQLGGTPVQL
YDQVKDGVVDVVWTLPGNTAGRFPRVDVFDLPFMMSNAEATSKAYWEYVQTVAVDEFKDTQVLALHVHGPGVIHTVNKPV
KSINDMRGLKLRAPTRQVTKLMGVLGAIPVGMPLPQIPDGLSKGTIEGCVIPWEVVPSVKVHELTKFHAEFDPAGGALYT
LTFVMAMNKAKYNSLPPDLKKVIDNNSGMATSAWLGKVQQGNDAAGRKSASDRGNTIYTVSAAEAQEFRRKSRAVEVEWV
EDMNKKGFDGKKLLDTARSLIEKHTKATKA

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=323, Percent_Identity=24.4582043343653, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 38375; Mature: 38375

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQRRTLLKSGAAVALGAPALSGLAQQVVTLKFHTFMSPQSNVWQSMHKPWMEKVEKESG
CCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
GRIKFEAYPAMQLGGTPVQLYDQVKDGVVDVVWTLPGNTAGRFPRVDVFDLPFMMSNAEA
CEEEEEECCCHHCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEECCCHHCCCCCH
TSKAYWEYVQTVAVDEFKDTQVLALHVHGPGVIHTVNKPVKSINDMRGLKLRAPTRQVTK
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCHHHHHHHHHCCCEEECCHHHHHH
LMGVLGAIPVGMPLPQIPDGLSKGTIEGCVIPWEVVPSVKVHELTKFHAEFDPAGGALYT
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECHHHCCCCHHHHHHHHHHCCCCCCCHHHH
LTFVMAMNKAKYNSLPPDLKKVIDNNSGMATSAWLGKVQQGNDAAGRKSASDRGNTIYTV
HHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEE
SAAEAQEFRRKSRAVEVEWVEDMNKKGFDGKKLLDTARSLIEKHTKATKA
EHHHHHHHHHHHCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIQRRTLLKSGAAVALGAPALSGLAQQVVTLKFHTFMSPQSNVWQSMHKPWMEKVEKESG
CCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
GRIKFEAYPAMQLGGTPVQLYDQVKDGVVDVVWTLPGNTAGRFPRVDVFDLPFMMSNAEA
CEEEEEECCCHHCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEECCCHHCCCCCH
TSKAYWEYVQTVAVDEFKDTQVLALHVHGPGVIHTVNKPVKSINDMRGLKLRAPTRQVTK
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCHHHHHHHHHCCCEEECCHHHHHH
LMGVLGAIPVGMPLPQIPDGLSKGTIEGCVIPWEVVPSVKVHELTKFHAEFDPAGGALYT
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECHHHCCCCHHHHHHHHHHCCCCCCCHHHH
LTFVMAMNKAKYNSLPPDLKKVIDNNSGMATSAWLGKVQQGNDAAGRKSASDRGNTIYTV
HHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEE
SAAEAQEFRRKSRAVEVEWVEDMNKKGFDGKKLLDTARSLIEKHTKATKA
EHHHHHHHHHHHCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA