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The map label for this gene is lrhA [H]

Identifier: 91787895

GI number: 91787895

Start: 2089691

End: 2090548

Strand: Reverse

Name: lrhA [H]

Synonym: Bpro_2019

Alternate gene names: 91787895

Gene position: 2090548-2089691 (Counterclockwise)

Preceding gene: 91787910

Following gene: 91787894

Centisome position: 40.2

GC content: 63.99

Gene sequence:

>858_bases
ATGCAAGACTTGGACCCGCACCTGTTGCGTGCATTCTTGTCGGTGATTGACGTCGGCACCGTCAATGGTGCCGCCGCCGC
CCTGCATCGCACCCAGGCGGCCGTCAGCATGCAGATCCGGCGCCTGGAAGACATTGCGGGCGCTCCGCTGTTTGAACGCT
CGCCCAAGGGCCTGACCGCCAACGCCGAGGGGCGGGTTCTGGAGCCCTATGCGCGTGAAATCCTGACCCTCAATGAAGAA
GCCCGGCAACGCATCAGCGGCCAGCGCATGGAGGGCCGCGTCAAGCTGGGGGTGGTGGAAGACTTTGCCGCAACGCGGCT
GATTGAGATTTTGAAGTCCTTTCGCGACCAGAACCCCAAGGTGCATCTGGACCTGATCATCGCAGGCAACAGGCAACTGG
CTGCGCTGTTTGAGCAGGACAAGCTCGACTTGCTGATCTGCGACACCCAGGAGGTGGCGCACAAGCCCCTGGTTGAATGG
CCCGAGCAGCTGCTGTGGGTGGTGCGCTCTGACCTGACGCTGATGCCGGACGATGCCTTGCCGGTAGTCCTGTTCACCGA
CGCCTGCCCCTGGCGCACCCGGGTCATGGAGTCGCTGGCCGACGCCCAGTTGCGCTGGAGCATGGTGTGCGAGGCCTCCA
CGCTGGTGGCCATGGCCACCGCCGTGCAGGTGGGCATTGGCATCGGACCCATGATTTCAGCCACCATTCCGCCCGGCTGC
CGCGTGCTGGCGGCAACGCCTGAATTCCCGAACCCGATTCAAATCGGCATTGGGCTGTATGCCCGCACCGGAGCCTCGGA
GGAAGCGACTTACCTCGCTGATTTCATGACCCGCATGCCGGGCAGGCTGGCGGTTTGA

Upstream 100 bases:

>100_bases
TACCCGCTTCGCAGCCCTCAAAAAATCTCAAAGTCATCGTAATGGCTCTGCTAAAGTAGCGATAGTCACAAAATTGTCGC
GCACCTATCAATAAAACTGA

Downstream 100 bases:

>100_bases
CGGGCATGCCGGTCAAGTCCACGCCGTTGCCGGAAGGTCTGGCCACAACGAACGCAAGCACGGGTACCGCGCGCAAGGCG
GGCGTCGACCATTACGAGAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MQDLDPHLLRAFLSVIDVGTVNGAAAALHRTQAAVSMQIRRLEDIAGAPLFERSPKGLTANAEGRVLEPYAREILTLNEE
ARQRISGQRMEGRVKLGVVEDFAATRLIEILKSFRDQNPKVHLDLIIAGNRQLAALFEQDKLDLLICDTQEVAHKPLVEW
PEQLLWVVRSDLTLMPDDALPVVLFTDACPWRTRVMESLADAQLRWSMVCEASTLVAMATAVQVGIGIGPMISATIPPGC
RVLAATPEFPNPIQIGIGLYARTGASEEATYLADFMTRMPGRLAV

Sequences:

>Translated_285_residues
MQDLDPHLLRAFLSVIDVGTVNGAAAALHRTQAAVSMQIRRLEDIAGAPLFERSPKGLTANAEGRVLEPYAREILTLNEE
ARQRISGQRMEGRVKLGVVEDFAATRLIEILKSFRDQNPKVHLDLIIAGNRQLAALFEQDKLDLLICDTQEVAHKPLVEW
PEQLLWVVRSDLTLMPDDALPVVLFTDACPWRTRVMESLADAQLRWSMVCEASTLVAMATAVQVGIGIGPMISATIPPGC
RVLAATPEFPNPIQIGIGLYARTGASEEATYLADFMTRMPGRLAV
>Mature_285_residues
MQDLDPHLLRAFLSVIDVGTVNGAAAALHRTQAAVSMQIRRLEDIAGAPLFERSPKGLTANAEGRVLEPYAREILTLNEE
ARQRISGQRMEGRVKLGVVEDFAATRLIEILKSFRDQNPKVHLDLIIAGNRQLAALFEQDKLDLLICDTQEVAHKPLVEW
PEQLLWVVRSDLTLMPDDALPVVLFTDACPWRTRVMESLADAQLRWSMVCEASTLVAMATAVQVGIGIGPMISATIPPGC
RVLAATPEFPNPIQIGIGLYARTGASEEATYLADFMTRMPGRLAV

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=248, Percent_Identity=32.6612903225806, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788297, Length=237, Percent_Identity=24.8945147679325, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787806, Length=122, Percent_Identity=31.9672131147541, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31303; Mature: 31303

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLDPHLLRAFLSVIDVGTVNGAAAALHRTQAAVSMQIRRLEDIAGAPLFERSPKGLTA
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NAEGRVLEPYAREILTLNEEARQRISGQRMEGRVKLGVVEDFAATRLIEILKSFRDQNPK
CCCCCEECHHHHHHHHCCHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCC
VHLDLIIAGNRQLAALFEQDKLDLLICDTQEVAHKPLVEWPEQLLWVVRSDLTLMPDDAL
EEEEEEEECCCCEEEHHCCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHCCCEECCCCCC
PVVLFTDACPWRTRVMESLADAQLRWSMVCEASTLVAMATAVQVGIGIGPMISATIPPGC
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCC
RVLAATPEFPNPIQIGIGLYARTGASEEATYLADFMTRMPGRLAV
EEEEECCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQDLDPHLLRAFLSVIDVGTVNGAAAALHRTQAAVSMQIRRLEDIAGAPLFERSPKGLTA
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NAEGRVLEPYAREILTLNEEARQRISGQRMEGRVKLGVVEDFAATRLIEILKSFRDQNPK
CCCCCEECHHHHHHHHCCHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCC
VHLDLIIAGNRQLAALFEQDKLDLLICDTQEVAHKPLVEWPEQLLWVVRSDLTLMPDDAL
EEEEEEEECCCCEEEHHCCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHCCCEECCCCCC
PVVLFTDACPWRTRVMESLADAQLRWSMVCEASTLVAMATAVQVGIGIGPMISATIPPGC
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCC
RVLAATPEFPNPIQIGIGLYARTGASEEATYLADFMTRMPGRLAV
EEEEECCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]