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The map label for this gene is acrR [H]

Identifier: 91787910

GI number: 91787910

Start: 2109796

End: 2110482

Strand: Reverse

Name: acrR [H]

Synonym: Bpro_2034

Alternate gene names: 91787910

Gene position: 2110482-2109796 (Counterclockwise)

Preceding gene: 91787914

Following gene: 91787895

Centisome position: 40.58

GC content: 60.7

Gene sequence:

>687_bases
GTGGCCCGTCGAACCAAAGAAGAGGCACTGGCGACCCGCAACAAGCTGCTTGATGCTGCCGAACACCTGTTTCAGGCACA
GGGAGTCTCACGCACCAGCCTGCAGGACATTGCCCGGCGCGCCGGTGCCACGCGTGGAGCCATTTATTGGCATTTCAGGG
ACAAGGCCGACCTGTTCAACGCCATGATGGAGCGGGTGACGCTGCCCATGGAAAAGTCGTTCGGCCTCGAGGGGAACGGA
GGGCAGGAATCCGCGGATAACTCAGGTGCCAGCGGCCTCGGCCGGATCCGCTCGGCCACTGTTAACGCGCTCAAGCAGAT
CGTGAACGACGCCCAGACCCGGCGCGTTTTCGAAGTGGCGACACAAAAAGTGGAGTATGTGGAAGAACTGCAGGCCGTTC
GTCTCCGGCATCTGGCAGTGCGCAACGGGTTTTTACAATTTTTTGAAGAGAGTATTGACCTCGCCGCGCGCCGATGCGGC
TTGAAACTGGCGGTGCCTGCCTCAGTGGCTGCACAGGGATTCCACGCCCTGATAGACGGCCTGATACAAAACTGGCTATT
GGATCCGCAAGCGTTTGACCTTCTCGAGGTGGGTCAAGGCGTGATGAACGTCTACCTGGGAGGCCTTGGCTTCACCGAAG
GGCCGCCCCCGGGCACCCCGGGAGAGACTGCGCCAACGCCTTCCTAA

Upstream 100 bases:

>100_bases
CCGAAATTGGAAGAGTAAGGGTTTTTACGAGTGGTATAGTTTACATACATTTATGAATGTATATAAGTACCCCTGCAAAT
GACCGTCAGGAGACAACGAA

Downstream 100 bases:

>100_bases
TGCAGATGCCGGGGCTTGCGCCCGCCGCCACCGTGGCCCGACCCACCCTGCGGCCCCCCAAGCCCGCGCGGTGGCTTGCC
GAGCTGCATGGAGTTGACCA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: Potential acrAB operon repressor [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MARRTKEEALATRNKLLDAAEHLFQAQGVSRTSLQDIARRAGATRGAIYWHFRDKADLFNAMMERVTLPMEKSFGLEGNG
GQESADNSGASGLGRIRSATVNALKQIVNDAQTRRVFEVATQKVEYVEELQAVRLRHLAVRNGFLQFFEESIDLAARRCG
LKLAVPASVAAQGFHALIDGLIQNWLLDPQAFDLLEVGQGVMNVYLGGLGFTEGPPPGTPGETAPTPS

Sequences:

>Translated_228_residues
MARRTKEEALATRNKLLDAAEHLFQAQGVSRTSLQDIARRAGATRGAIYWHFRDKADLFNAMMERVTLPMEKSFGLEGNG
GQESADNSGASGLGRIRSATVNALKQIVNDAQTRRVFEVATQKVEYVEELQAVRLRHLAVRNGFLQFFEESIDLAARRCG
LKLAVPASVAAQGFHALIDGLIQNWLLDPQAFDLLEVGQGVMNVYLGGLGFTEGPPPGTPGETAPTPS
>Mature_227_residues
ARRTKEEALATRNKLLDAAEHLFQAQGVSRTSLQDIARRAGATRGAIYWHFRDKADLFNAMMERVTLPMEKSFGLEGNGG
QESADNSGASGLGRIRSATVNALKQIVNDAQTRRVFEVATQKVEYVEELQAVRLRHLAVRNGFLQFFEESIDLAARRCGL
KLAVPASVAAQGFHALIDGLIQNWLLDPQAFDLLEVGQGVMNVYLGGLGFTEGPPPGTPGETAPTPS

Specific function: Potential regulator protein for the acrAB genes [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786669, Length=201, Percent_Identity=37.8109452736318, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1789664, Length=203, Percent_Identity=30.0492610837438, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013572
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08361 TetR_C_2; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24807; Mature: 24676

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRTKEEALATRNKLLDAAEHLFQAQGVSRTSLQDIARRAGATRGAIYWHFRDKADLFN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHH
AMMERVTLPMEKSFGLEGNGGQESADNSGASGLGRIRSATVNALKQIVNDAQTRRVFEVA
HHHHHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQKVEYVEELQAVRLRHLAVRNGFLQFFEESIDLAARRCGLKLAVPASVAAQGFHALIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHH
LIQNWLLDPQAFDLLEVGQGVMNVYLGGLGFTEGPPPGTPGETAPTPS
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARRTKEEALATRNKLLDAAEHLFQAQGVSRTSLQDIARRAGATRGAIYWHFRDKADLFN
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHH
AMMERVTLPMEKSFGLEGNGGQESADNSGASGLGRIRSATVNALKQIVNDAQTRRVFEVA
HHHHHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQKVEYVEELQAVRLRHLAVRNGFLQFFEESIDLAARRCGLKLAVPASVAAQGFHALIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHH
LIQNWLLDPQAFDLLEVGQGVMNVYLGGLGFTEGPPPGTPGETAPTPS
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]