Click here to switch to the map view.

The map label for this gene is dapL [H]

Identifier: 91787873

GI number: 91787873

Start: 2064722

End: 2065939

Strand: Reverse

Name: dapL [H]

Synonym: Bpro_1997

Alternate gene names: 91787873

Gene position: 2065939-2064722 (Counterclockwise)

Preceding gene: 91787875

Following gene: 91787872

Centisome position: 39.73

GC content: 64.37

Gene sequence:

>1218_bases
ATGAATCCCCTGCTTTCCCGCCTCCAGCCCTATCCTTTTGAGCGTCTGCGCCAATTGCACGCCGGCGTCACCCCCAACCC
CGCCTACCGGCCCATCAGCCTGGGTATCGGCGAGCCCCGGCATGCGACGCCGCAACTCGTCAAGGATGCACTGACGGCCA
GCCTGAGTGGCCTGGCGAGCTACCCCGGTACGCTGGGCGAGCCCAAATTGCGCCAGGCCATGAGCGACTGGCTGGCCCGC
CGCTATGGCCTGTCGATTGACCCGGCCACGCAAATCCTGCCCGTGAACGGCTCGCGGGAAGCGCTTTTTTCACTGGCGCA
GACGGTGCTGGACGCCAGCAAGCCGGGCGCCACCGTGGTCTGTCCCAATCCTTTTTACCAAATCTACGAAGGCGCCGCGC
TGCTGGGCGGCGCGCAGACCTGGTTTGCGCCCAGCGACCCGGCACGGAATTTTGCGGTGGACTGGGCGGGCGTGCCGGAG
ACCGTATGGGCCAAGACCCAGCTGGTGTTTGTCTGCTCGCCCGGCAACCCTACCGGCGCGGTGATGTCGCTGGCGGAGTG
GGAACTGCTGTTCAAGCTGAGCGACCGGTACGGCTTTGTGATCGCCTCGGACGAGTGCTACAGCGAAATCTACTTCCGCG
AAGGTGACGCTGGAGGGGCGCCGCTGGGCGGGCTGCAGGCCGCGGCGCAATTGGGCCGGCATGACTTCAAAAACCTGATT
TCGCTGACCAGCCTGTCCAAGCGCAGCAATGTGCCGGGCCTGCGCAGCGGCTTTGTGGCGGGCGACGCGGCGCTGATCAA
GCCTTTTTTGCTCTACCGCACCTACCACGGCAGTGCCATGAGCCCGGTGGTGCAGGCCGCCAGCATTGCGGCCTGGAACG
ACGAGCAGCATGTGGTGGAAAACCGGGCCCTGTACCGCGAAAAATTTGCCCGGGTCACGCCCCTGCTGGCCTCTGTGATG
GAAGTGGCCCTGCCTGATGCCGGTTTTTACCTGTGGGCCGGCATACCTGACATATTCAGGGGTTCCGACACCGAATTCTC
GCGCGAGCTGCTCGCTCTTTACAATGTCGTGGTGTTGCCGGGCAGTTACCTGGCGCGCGATGCCCAAGGCCATAACCCCG
GCGCCGGCAGAATCCGCATGGCACTGGTGGCGGAAACTGCCGAATGCGTGGAAGCCGCGGAGCGCATCGTTCAGTTCATT
CAATCCAAAGCTCGCTGA

Upstream 100 bases:

>100_bases
CAACCGGTCGCGTGCATTCAACCGGCTTCAAGCGGACGTCTGGCGCGCCTCGGACACAACACAATCCCCTTCCCCACGCC
AAGGCTGGATAATCTGGGGC

Downstream 100 bases:

>100_bases
AAAACCCTAACGAAGACTCACTCCATGACACAAGACAACCTGCAAAGCGCCCTCCAGAACACGATTGACGCGGCCTGGGA
AGATCGCGCCAACCTGTCGC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MNPLLSRLQPYPFERLRQLHAGVTPNPAYRPISLGIGEPRHATPQLVKDALTASLSGLASYPGTLGEPKLRQAMSDWLAR
RYGLSIDPATQILPVNGSREALFSLAQTVLDASKPGATVVCPNPFYQIYEGAALLGGAQTWFAPSDPARNFAVDWAGVPE
TVWAKTQLVFVCSPGNPTGAVMSLAEWELLFKLSDRYGFVIASDECYSEIYFREGDAGGAPLGGLQAAAQLGRHDFKNLI
SLTSLSKRSNVPGLRSGFVAGDAALIKPFLLYRTYHGSAMSPVVQAASIAAWNDEQHVVENRALYREKFARVTPLLASVM
EVALPDAGFYLWAGIPDIFRGSDTEFSRELLALYNVVVLPGSYLARDAQGHNPGAGRIRMALVAETAECVEAAERIVQFI
QSKAR

Sequences:

>Translated_405_residues
MNPLLSRLQPYPFERLRQLHAGVTPNPAYRPISLGIGEPRHATPQLVKDALTASLSGLASYPGTLGEPKLRQAMSDWLAR
RYGLSIDPATQILPVNGSREALFSLAQTVLDASKPGATVVCPNPFYQIYEGAALLGGAQTWFAPSDPARNFAVDWAGVPE
TVWAKTQLVFVCSPGNPTGAVMSLAEWELLFKLSDRYGFVIASDECYSEIYFREGDAGGAPLGGLQAAAQLGRHDFKNLI
SLTSLSKRSNVPGLRSGFVAGDAALIKPFLLYRTYHGSAMSPVVQAASIAAWNDEQHVVENRALYREKFARVTPLLASVM
EVALPDAGFYLWAGIPDIFRGSDTEFSRELLALYNVVVLPGSYLARDAQGHNPGAGRIRMALVAETAECVEAAERIVQFI
QSKAR
>Mature_405_residues
MNPLLSRLQPYPFERLRQLHAGVTPNPAYRPISLGIGEPRHATPQLVKDALTASLSGLASYPGTLGEPKLRQAMSDWLAR
RYGLSIDPATQILPVNGSREALFSLAQTVLDASKPGATVVCPNPFYQIYEGAALLGGAQTWFAPSDPARNFAVDWAGVPE
TVWAKTQLVFVCSPGNPTGAVMSLAEWELLFKLSDRYGFVIASDECYSEIYFREGDAGGAPLGGLQAAAQLGRHDFKNLI
SLTSLSKRSNVPGLRSGFVAGDAALIKPFLLYRTYHGSAMSPVVQAASIAAWNDEQHVVENRALYREKFARVTPLLASVM
EVALPDAGFYLWAGIPDIFRGSDTEFSRELLALYNVVVLPGSYLARDAQGHNPGAGRIRMALVAETAECVEAAERIVQFI
QSKAR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=396, Percent_Identity=24.4949494949495, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI56713254, Length=396, Percent_Identity=24.4949494949495, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI95147551, Length=335, Percent_Identity=23.8805970149254, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI169881279, Length=335, Percent_Identity=23.8805970149254, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788722, Length=406, Percent_Identity=28.3251231527094, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=25.1322751322751, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=435, Percent_Identity=23.6781609195402, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=435, Percent_Identity=23.6781609195402, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=413, Percent_Identity=22.7602905569007, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320317, Length=392, Percent_Identity=25.5102040816327, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28573069, Length=252, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646114, Length=252, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573067, Length=252, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573065, Length=252, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43897; Mature: 43897

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLLSRLQPYPFERLRQLHAGVTPNPAYRPISLGIGEPRHATPQLVKDALTASLSGLAS
CCCHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
YPGTLGEPKLRQAMSDWLARRYGLSIDPATQILPVNGSREALFSLAQTVLDASKPGATVV
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEE
CPNPFYQIYEGAALLGGAQTWFAPSDPARNFAVDWAGVPETVWAKTQLVFVCSPGNPTGA
CCCHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCEEEEEEECCCCCHHH
VMSLAEWELLFKLSDRYGFVIASDECYSEIYFREGDAGGAPLGGLQAAAQLGRHDFKNLI
HHHHHHHHHHEEECCCCEEEEECHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHH
SLTSLSKRSNVPGLRSGFVAGDAALIKPFLLYRTYHGSAMSPVVQAASIAAWNDEQHVVE
HHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHH
NRALYREKFARVTPLLASVMEVALPDAGFYLWAGIPDIFRGSDTEFSRELLALYNVVVLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHCC
GSYLARDAQGHNPGAGRIRMALVAETAECVEAAERIVQFIQSKAR
CHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPLLSRLQPYPFERLRQLHAGVTPNPAYRPISLGIGEPRHATPQLVKDALTASLSGLAS
CCCHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
YPGTLGEPKLRQAMSDWLARRYGLSIDPATQILPVNGSREALFSLAQTVLDASKPGATVV
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEE
CPNPFYQIYEGAALLGGAQTWFAPSDPARNFAVDWAGVPETVWAKTQLVFVCSPGNPTGA
CCCHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCEEEEEEECCCCCHHH
VMSLAEWELLFKLSDRYGFVIASDECYSEIYFREGDAGGAPLGGLQAAAQLGRHDFKNLI
HHHHHHHHHHEEECCCCEEEEECHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHH
SLTSLSKRSNVPGLRSGFVAGDAALIKPFLLYRTYHGSAMSPVVQAASIAAWNDEQHVVE
HHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHH
NRALYREKFARVTPLLASVMEVALPDAGFYLWAGIPDIFRGSDTEFSRELLALYNVVVLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHCC
GSYLARDAQGHNPGAGRIRMALVAETAECVEAAERIVQFIQSKAR
CHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA