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The map label for this gene is siaT [H]

Identifier: 91787184

GI number: 91787184

Start: 1329756

End: 1331036

Strand: Reverse

Name: siaT [H]

Synonym: Bpro_1288

Alternate gene names: 91787184

Gene position: 1331036-1329756 (Counterclockwise)

Preceding gene: 91787185

Following gene: 91787183

Centisome position: 25.6

GC content: 62.06

Gene sequence:

>1281_bases
ATGAGTATCGCGCTGCTGCTGATTTTTCTCGTCCTGTCGGCGCTTGGCGTCCCGCTGGCCATTGCGTTGGGCCTGTCCGG
CGTGGCCAGCGTCTTCATGTTCACCTCGACGCCGCTGAACCTGTTGTCCGAGAGCATGTTTTCAGCGATGAATTCCTTCC
TGCTGGTTGCGGTTCCGCTGTTCCTGCTGGTCGGTCAGTTGATGGAACGCGGCGGGGTCGCCGACCGGATTTTCGACTTT
GCCCATGCGGCCGTCGGCTGGCTGCCTGGCGGCATGGGCCATGTCAACGTAACCTCCTCGGTGGTCTTCGGCGGCATCTC
GGGCTCCTCGGTCGCCGACATCGCCTCGCTGGGCGCAGTCGAGATCAATGCCATGACGCGGCATGGCTACGACAAGGGCT
ATGCGGTCGGCATGACACTGACCACCTCGACCCTGTCCTCGATCATTCCGCCCTCGATCCTGATGGTGATTGCAGGCTCG
ATCGCCAGCCAGTCGATCGGCCTGCTACTGGTCGCCGGCCTGATCCCCGGCCTGTTTATCGCCGCCATGCTGATGGTCTA
CAACCACTTCTACAGCGTGCGCAAAGGCGTCGGCAAGCCCATGCCCTTCAGCGGGGGGCTGCTGCTGCGTGCCGGTCTGC
GCGCGATCCTGCCGATGATGACACCGGTGATCCTGATGATCGGCATTCTGGACGGCTTCTTCACCCCGACCGAAGCCGCC
GCGATTGCCGTGGTCTACACGCTTTCGATTGCAGCAGTGATCTACCGCCGGATCAAGTGGAAGGACATCGCCCCGATGCT
GATCGATACCGCACGGACCAGCGGCAACATCCTGTTCATCGCAGCCACGGCCAAGCTGGCGGCCTGGGTCTTCGCTTATG
ACGGCCTGCCGGTGCAGGTCGGCAATGCCTTGGGTTCGATCACCACCAACCCCATGCTGATCATGCTGCTGATCTTCCTG
TTCCTGGTGGTAGTCGGCATGTTCATGGATGCCATCGCGGCCATGTTCATCCTGATTCCGGTGCTGCTGCCGCCGGCCGT
AGCCCTGGGCATCGACCCGATTCACCTGCTGGTGATTGTGGTCGTCACATTGACCCTGGGTCTGGTGACGCCCCCGGTGG
GCGTCTGTCTGTTCGCCGCGGCGAAGGTGGCAGACATGTCCGTGGAGGAGGTCATCAAGGGCTCAATCGGCCCCGTCTCG
GTTCTGATCCTCTCCATCCTCGCCATGGTTCTTTTCCCCGTGCTGGTCATCGGTCCACTGCGCCTGTTTGGCATGTACTG
A

Upstream 100 bases:

>100_bases
CGATTTTGGCCATTCTCTGCACGCTGGAGTCCTTGCGCCAGCACCGCGCCGCCATCGCTCTCGATCCTTCGAAAGCCACA
CCCAAACAGGAAGCTGCATC

Downstream 100 bases:

>100_bases
CGCCGCACAACTCCACCCCATCCATCCACCCCCCATCCACTCACCCCATTCACAGGAGTATTCCCCATGTTCGTCGGTAA
ACAAGTCCGCCTCAAACGCC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSIALLLIFLVLSALGVPLAIALGLSGVASVFMFTSTPLNLLSESMFSAMNSFLLVAVPLFLLVGQLMERGGVADRIFDF
AHAAVGWLPGGMGHVNVTSSVVFGGISGSSVADIASLGAVEINAMTRHGYDKGYAVGMTLTTSTLSSIIPPSILMVIAGS
IASQSIGLLLVAGLIPGLFIAAMLMVYNHFYSVRKGVGKPMPFSGGLLLRAGLRAILPMMTPVILMIGILDGFFTPTEAA
AIAVVYTLSIAAVIYRRIKWKDIAPMLIDTARTSGNILFIAATAKLAAWVFAYDGLPVQVGNALGSITTNPMLIMLLIFL
FLVVVGMFMDAIAAMFILIPVLLPPAVALGIDPIHLLVIVVVTLTLGLVTPPVGVCLFAAAKVADMSVEEVIKGSIGPVS
VLILSILAMVLFPVLVIGPLRLFGMY

Sequences:

>Translated_426_residues
MSIALLLIFLVLSALGVPLAIALGLSGVASVFMFTSTPLNLLSESMFSAMNSFLLVAVPLFLLVGQLMERGGVADRIFDF
AHAAVGWLPGGMGHVNVTSSVVFGGISGSSVADIASLGAVEINAMTRHGYDKGYAVGMTLTTSTLSSIIPPSILMVIAGS
IASQSIGLLLVAGLIPGLFIAAMLMVYNHFYSVRKGVGKPMPFSGGLLLRAGLRAILPMMTPVILMIGILDGFFTPTEAA
AIAVVYTLSIAAVIYRRIKWKDIAPMLIDTARTSGNILFIAATAKLAAWVFAYDGLPVQVGNALGSITTNPMLIMLLIFL
FLVVVGMFMDAIAAMFILIPVLLPPAVALGIDPIHLLVIVVVTLTLGLVTPPVGVCLFAAAKVADMSVEEVIKGSIGPVS
VLILSILAMVLFPVLVIGPLRLFGMY
>Mature_425_residues
SIALLLIFLVLSALGVPLAIALGLSGVASVFMFTSTPLNLLSESMFSAMNSFLLVAVPLFLLVGQLMERGGVADRIFDFA
HAAVGWLPGGMGHVNVTSSVVFGGISGSSVADIASLGAVEINAMTRHGYDKGYAVGMTLTTSTLSSIIPPSILMVIAGSI
ASQSIGLLLVAGLIPGLFIAAMLMVYNHFYSVRKGVGKPMPFSGGLLLRAGLRAILPMMTPVILMIGILDGFFTPTEAAA
IAVVYTLSIAAVIYRRIKWKDIAPMLIDTARTSGNILFIAATAKLAAWVFAYDGLPVQVGNALGSITTNPMLIMLLIFLF
LVVVGMFMDAIAAMFILIPVLLPPAVALGIDPIHLLVIVVVTLTLGLVTPPVGVCLFAAAKVADMSVEEVIKGSIGPVSV
LILSILAMVLFPVLVIGPLRLFGMY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=408, Percent_Identity=33.3333333333333, Blast_Score=195, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44517; Mature: 44386

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIALLLIFLVLSALGVPLAIALGLSGVASVFMFTSTPLNLLSESMFSAMNSFLLVAVPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FLLVGQLMERGGVADRIFDFAHAAVGWLPGGMGHVNVTSSVVFGGISGSSVADIASLGAV
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCHHHHHHHCCCC
EINAMTRHGYDKGYAVGMTLTTSTLSSIIPPSILMVIAGSIASQSIGLLLVAGLIPGLFI
EEEHHHHCCCCCCEEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMLMVYNHFYSVRKGVGKPMPFSGGLLLRAGLRAILPMMTPVILMIGILDGFFTPTEAA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AIAVVYTLSIAAVIYRRIKWKDIAPMLIDTARTSGNILFIAATAKLAAWVFAYDGLPVQV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCEEH
GNALGSITTNPMLIMLLIFLFLVVVGMFMDAIAAMFILIPVLLPPAVALGIDPIHLLVIV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHH
VVTLTLGLVTPPVGVCLFAAAKVADMSVEEVIKGSIGPVSVLILSILAMVLFPVLVIGPL
HHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLFGMY
HHHCCC
>Mature Secondary Structure 
SIALLLIFLVLSALGVPLAIALGLSGVASVFMFTSTPLNLLSESMFSAMNSFLLVAVPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FLLVGQLMERGGVADRIFDFAHAAVGWLPGGMGHVNVTSSVVFGGISGSSVADIASLGAV
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCHHHHHHHCCCC
EINAMTRHGYDKGYAVGMTLTTSTLSSIIPPSILMVIAGSIASQSIGLLLVAGLIPGLFI
EEEHHHHCCCCCCEEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMLMVYNHFYSVRKGVGKPMPFSGGLLLRAGLRAILPMMTPVILMIGILDGFFTPTEAA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AIAVVYTLSIAAVIYRRIKWKDIAPMLIDTARTSGNILFIAATAKLAAWVFAYDGLPVQV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCEEH
GNALGSITTNPMLIMLLIFLFLVVVGMFMDAIAAMFILIPVLLPPAVALGIDPIHLLVIV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHH
VVTLTLGLVTPPVGVCLFAAAKVADMSVEEVIKGSIGPVSVLILSILAMVLFPVLVIGPL
HHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLFGMY
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]