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The map label for this gene is ruvC

Identifier: 91786981

GI number: 91786981

Start: 1116245

End: 1116793

Strand: Reverse

Name: ruvC

Synonym: Bpro_1083

Alternate gene names: 91786981

Gene position: 1116793-1116245 (Counterclockwise)

Preceding gene: 91786982

Following gene: 91786959

Centisome position: 21.48

GC content: 65.39

Gene sequence:

>549_bases
ATGCGTATTCTTGGAATTGACCCTGGCTTGCAGATCGCCGGATTCGGCGTGGTCGAAGTCGACGGCCCCCACTTGCACTA
TGTGGCCAGCGGCACCATCAAGACCACGCACATGGTGCGCGGCGACCTGCCGGCCCGGCTGAAGGTGCTGTTTGACGGGG
TACGGGAAGTGGTGCAGCGCTACCAGCCCGACATGGCCTCGGTGGAGATCGTCTTTACCAACGTCAACCCACAGGCCACG
CTGCTGCTGGGGCAGGCGCGCGGTGCCTGCATCACGGCCCTGGTCTCCAGCGATCTCACCGTGGCCGAATACACGGCCCT
GCAAATGAAGAAGGCGGTGGCCGGCTATGGCAAGGCCGGCAAGGCCGAGGTCCAGCAGATGGTGATGCGGCTGCTGAAAT
TGCCGGCCCTGCCCGGCAAGGACGCCGCCGATGCCCTGGGCCTGGCCATCACCCATGCCCATGCCGGGCGTTCAACGGCC
ATCCTGGCGGCCGCCACGGCGTTGAAGCCCAACGCCAGCGCTTCTTACAAGGCGGGTCGGCACTATTGA

Upstream 100 bases:

>100_bases
CCGATATTCTTCCATTCGGTTCGATGGTATTTTGGCCTCTAGCCCTTTCATTTCACTTTCATTTCAAATCCTGCGCAAGC
AGCTACCAAATTTATAGCCT

Downstream 100 bases:

>100_bases
GCCCAACGCTTTTCGCTTCATGTAATGCGCGGCCATCTGAAGGAACCGTTTTTCGCTGGGCCTGCCCGGCAGAAAGACTG
CAGCACGCCTTCTCAGGCCA

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MRILGIDPGLQIAGFGVVEVDGPHLHYVASGTIKTTHMVRGDLPARLKVLFDGVREVVQRYQPDMASVEIVFTNVNPQAT
LLLGQARGACITALVSSDLTVAEYTALQMKKAVAGYGKAGKAEVQQMVMRLLKLPALPGKDAADALGLAITHAHAGRSTA
ILAAATALKPNASASYKAGRHY

Sequences:

>Translated_182_residues
MRILGIDPGLQIAGFGVVEVDGPHLHYVASGTIKTTHMVRGDLPARLKVLFDGVREVVQRYQPDMASVEIVFTNVNPQAT
LLLGQARGACITALVSSDLTVAEYTALQMKKAVAGYGKAGKAEVQQMVMRLLKLPALPGKDAADALGLAITHAHAGRSTA
ILAAATALKPNASASYKAGRHY
>Mature_182_residues
MRILGIDPGLQIAGFGVVEVDGPHLHYVASGTIKTTHMVRGDLPARLKVLFDGVREVVQRYQPDMASVEIVFTNVNPQAT
LLLGQARGACITALVSSDLTVAEYTALQMKKAVAGYGKAGKAEVQQMVMRLLKLPALPGKDAADALGLAITHAHAGRSTA
ILAAATALKPNASASYKAGRHY

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=156, Percent_Identity=49.3589743589744, Blast_Score=130, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_POLSJ (Q12EK7)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_547933.1
- ProteinModelPortal:   Q12EK7
- SMR:   Q12EK7
- STRING:   Q12EK7
- GeneID:   4012090
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_1083
- NMPDR:   fig|296591.1.peg.3322
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- PhylomeDB:   Q12EK7
- ProtClustDB:   PRK00039
- BioCyc:   PSP296591:BPRO_1083-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 19157; Mature: 19157

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIDPGLQIAGFGVVEVDGPHLHYVASGTIKTTHMVRGDLPARLKVLFDGVREVVQR
CEEEECCCCCEEECEEEEEECCCEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
YQPDMASVEIVFTNVNPQATLLLGQARGACITALVSSDLTVAEYTALQMKKAVAGYGKAG
HCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCCC
KAEVQQMVMRLLKLPALPGKDAADALGLAITHAHAGRSTAILAAATALKPNASASYKAGR
HHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEECCCCCCCEEEEEEHHCCCCCCCCCCCCC
HY
CC
>Mature Secondary Structure
MRILGIDPGLQIAGFGVVEVDGPHLHYVASGTIKTTHMVRGDLPARLKVLFDGVREVVQR
CEEEECCCCCEEECEEEEEECCCEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
YQPDMASVEIVFTNVNPQATLLLGQARGACITALVSSDLTVAEYTALQMKKAVAGYGKAG
HCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEHHHCCCCHHHHHHHHHHHHHHCCCCCC
KAEVQQMVMRLLKLPALPGKDAADALGLAITHAHAGRSTAILAAATALKPNASASYKAGR
HHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEECCCCCCCEEEEEEHHCCCCCCCCCCCCC
HY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA