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The map label for this gene is bioD [H]

Identifier: 91786801

GI number: 91786801

Start: 917359

End: 918057

Strand: Reverse

Name: bioD [H]

Synonym: Bpro_0899

Alternate gene names: 91786801

Gene position: 918057-917359 (Counterclockwise)

Preceding gene: 91786802

Following gene: 91786800

Centisome position: 17.65

GC content: 66.81

Gene sequence:

>699_bases
ATGGCTGAGCATCCGAAAATTTCCTTTTTCGTGACCGGCACCGATACCGGCGTGGGCAAGACCCTGGTCAGTGCGGCGCT
GCTGCATGCGCTGGCCCCGCACTACCCGCGCGTGGTCGGCATGAAGCCGGTGGCAGCAGGCACCACCTTGATGGACGGCT
TGCAAGCCAACGACGACGTGCTGGCCCTGCGCGCTGCATCCAGCTGCCGCGTACCCCCCGAACTGGACAATCCCGTTTTG
CTGCCCGACGCGGTGTCGCCGCACATTGCCGCCACGCGCGCTGGCGTTCGCATAGCCATCGCCCATATCGTGGCCTGCCA
CCGCCAATTACTGCAGCTGGCTGACGCCGTGGTGGTGGAAGGCGCAGGCGGCTTCATGGTGCCGCTGTCGGATACGGAAA
CCGGCGCGGATCTGGCGCAGGCCCTGGGCTTGCCCGTGGTACTGGTGGTGGGCCTGCGCCTGGGCTGCCTCAACCACGCG
CTGCTGACGGCCGCCGCCATTCGCGCGCGCGGCCTCACGCTGGCGGGCTGGGTGGCCAACCATATAGACCCCAGCATGCT
CGCGCAAGGCGACAACATCGCCTTTTTGCAGCACCAGCTGGCCGCACCGCTGCTGGCCAGCATTGCGCACCAGTCGCAGC
CCGACCCCAAAACCCTGAACCTGGAACTCCCCCTGGCATGGCAATCAACACCCCACTGA

Upstream 100 bases:

>100_bases
TACGCCATGCCGCCGTATGTGATGGACGAGGAAAGCTCCGGTTTTCTGGCACGCGGCGCGCTGGCGGCCCTGCAGGCCAC
GCTGGCCGAAGAAGCTGCGC

Downstream 100 bases:

>100_bases
CAAATTCCTGGCTCGATGAATTTCCGGCGCGCATTGCCGAGCTGGACCGCGCGCATTTGCGCCGCCGGCGTCGCGTCGTC
GTGCCTGAAGATGGCGCCCA

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAEHPKISFFVTGTDTGVGKTLVSAALLHALAPHYPRVVGMKPVAAGTTLMDGLQANDDVLALRAASSCRVPPELDNPVL
LPDAVSPHIAATRAGVRIAIAHIVACHRQLLQLADAVVVEGAGGFMVPLSDTETGADLAQALGLPVVLVVGLRLGCLNHA
LLTAAAIRARGLTLAGWVANHIDPSMLAQGDNIAFLQHQLAAPLLASIAHQSQPDPKTLNLELPLAWQSTPH

Sequences:

>Translated_232_residues
MAEHPKISFFVTGTDTGVGKTLVSAALLHALAPHYPRVVGMKPVAAGTTLMDGLQANDDVLALRAASSCRVPPELDNPVL
LPDAVSPHIAATRAGVRIAIAHIVACHRQLLQLADAVVVEGAGGFMVPLSDTETGADLAQALGLPVVLVVGLRLGCLNHA
LLTAAAIRARGLTLAGWVANHIDPSMLAQGDNIAFLQHQLAAPLLASIAHQSQPDPKTLNLELPLAWQSTPH
>Mature_231_residues
AEHPKISFFVTGTDTGVGKTLVSAALLHALAPHYPRVVGMKPVAAGTTLMDGLQANDDVLALRAASSCRVPPELDNPVLL
PDAVSPHIAATRAGVRIAIAHIVACHRQLLQLADAVVVEGAGGFMVPLSDTETGADLAQALGLPVVLVVGLRLGCLNHAL
LTAAAIRARGLTLAGWVANHIDPSMLAQGDNIAFLQHQLAAPLLASIAHQSQPDPKTLNLELPLAWQSTPH

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=201, Percent_Identity=47.2636815920398, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87081944, Length=219, Percent_Identity=39.7260273972603, Blast_Score=133, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24095; Mature: 23964

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHPKISFFVTGTDTGVGKTLVSAALLHALAPHYPRVVGMKPVAAGTTLMDGLQANDDV
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHCCCCCCCE
LALRAASSCRVPPELDNPVLLPDAVSPHIAATRAGVRIAIAHIVACHRQLLQLADAVVVE
EEEEECCCCCCCCCCCCCEECCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEE
GAGGFMVPLSDTETGADLAQALGLPVVLVVGLRLGCLNHALLTAAAIRARGLTLAGWVAN
CCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHH
HIDPSMLAQGDNIAFLQHQLAAPLLASIAHQSQPDPKTLNLELPLAWQSTPH
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
AEHPKISFFVTGTDTGVGKTLVSAALLHALAPHYPRVVGMKPVAAGTTLMDGLQANDDV
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHCCCCCCCE
LALRAASSCRVPPELDNPVLLPDAVSPHIAATRAGVRIAIAHIVACHRQLLQLADAVVVE
EEEEECCCCCCCCCCCCCEECCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEE
GAGGFMVPLSDTETGADLAQALGLPVVLVVGLRLGCLNHALLTAAAIRARGLTLAGWVAN
CCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHH
HIDPSMLAQGDNIAFLQHQLAAPLLASIAHQSQPDPKTLNLELPLAWQSTPH
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA