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The map label for this gene is cyoC [H]

Identifier: 91786631

GI number: 91786631

Start: 744580

End: 745290

Strand: Direct

Name: cyoC [H]

Synonym: Bpro_0729

Alternate gene names: 91786631

Gene position: 744580-745290 (Clockwise)

Preceding gene: 91786630

Following gene: 91786632

Centisome position: 14.32

GC content: 63.99

Gene sequence:

>711_bases
ATGGACACCACGATACCAATGGCTTCACCCCCAAGCGCTGCCGTTAGCGCCGCCAGCGCGGGAGTCGGCTGGCGCGGGCT
GGTGTCCGACTGGTCGTCCGACCGCGAGGCTTTCCACGTCTCGTGGGGCAAGGCGATGATGTGGATCTTCCTGCTCAGCG
ACACCTTCATCTTCAGCTGCTTCCTCACGGGCTACATGACGGTGCGCGTCTCGACCACCGTGCCCTGGCCCAACCCCAGC
CAGGTGTTCGCCCTGCACGTGGGCGGCACGGAGGTGCCCCTGCTGCTGATCGCCATCATGACCTTTGTGCTCATCAGCAG
CAGCGGCACCATGGCCATGGCGGTGAACTGCGCTTACCGGCGTGACCGCATCAACGCGGCCGTGCTGATGATTGTGACTG
CCACGCTGGGCGAGACCTTCGTCGCCATGCAGGCCTTCGAATGGTCCAAGCTGATACTCGAGGAGGGCGTGCGGCCCTGG
GGCAACCCCATGGGCGCGGCCCAGTTCGGCTCGGCCTTCTTCATGATCACCGGCTTTCACGGCCTGCACGTGACCGCCGG
CGTCATCTACCTGCTGGTGGTGGCCACACGCCTGCTGCGCGGCCGCTACGAACAGTCGGGCAACTACCAGATCGTGGAGA
TCGTCGGCCTGTACTGGCACTTCGTCGACCTCGTCTGGGTGTTCATCTTTGCGTTTTTCTATCTCTGGTGA

Upstream 100 bases:

>100_bases
GTGGGTGGTGCTGTTTGCGACGCTCGGCTGGCTGACGCCGGAAGCCGTGCGCTGGATCTGCGGCACGGGCTGACGGCCGG
CATGAACTTCTGGAGGCTCC

Downstream 100 bases:

>100_bases
CAGTCCCTGCTGAAAGCTTGACCATGTCCTCCTCCCCATCGCCATCCTCATCGCCATCCTCCACCGGCCAGCAGCATCCG
ATCGGCCTGTACCTCAAGGT

Product: cytochrome c oxidase subunit III

Products: Ubiquinone-8; H2O. [C]

Alternate protein names: Cytochrome o ubiquinol oxidase subunit III; Ubiquinol oxidase chain C [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MDTTIPMASPPSAAVSAASAGVGWRGLVSDWSSDREAFHVSWGKAMMWIFLLSDTFIFSCFLTGYMTVRVSTTVPWPNPS
QVFALHVGGTEVPLLLIAIMTFVLISSSGTMAMAVNCAYRRDRINAAVLMIVTATLGETFVAMQAFEWSKLILEEGVRPW
GNPMGAAQFGSAFFMITGFHGLHVTAGVIYLLVVATRLLRGRYEQSGNYQIVEIVGLYWHFVDLVWVFIFAFFYLW

Sequences:

>Translated_236_residues
MDTTIPMASPPSAAVSAASAGVGWRGLVSDWSSDREAFHVSWGKAMMWIFLLSDTFIFSCFLTGYMTVRVSTTVPWPNPS
QVFALHVGGTEVPLLLIAIMTFVLISSSGTMAMAVNCAYRRDRINAAVLMIVTATLGETFVAMQAFEWSKLILEEGVRPW
GNPMGAAQFGSAFFMITGFHGLHVTAGVIYLLVVATRLLRGRYEQSGNYQIVEIVGLYWHFVDLVWVFIFAFFYLW
>Mature_236_residues
MDTTIPMASPPSAAVSAASAGVGWRGLVSDWSSDREAFHVSWGKAMMWIFLLSDTFIFSCFLTGYMTVRVSTTVPWPNPS
QVFALHVGGTEVPLLLIAIMTFVLISSSGTMAMAVNCAYRRDRINAAVLMIVTATLGETFVAMQAFEWSKLILEEGVRPW
GNPMGAAQFGSAFFMITGFHGLHVTAGVIYLLVVATRLLRGRYEQSGNYQIVEIVGLYWHFVDLVWVFIFAFFYLW

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration [H]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=148, Percent_Identity=32.4324324324324, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786633, Length=190, Percent_Identity=33.6842105263158, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833
- InterPro:   IPR014206 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: 1.10.3.- [C]

Molecular weight: Translated: 26179; Mature: 26179

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTTIPMASPPSAAVSAASAGVGWRGLVSDWSSDREAFHVSWGKAMMWIFLLSDTFIFSC
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
FLTGYMTVRVSTTVPWPNPSQVFALHVGGTEVPLLLIAIMTFVLISSSGTMAMAVNCAYR
HHHCEEEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
RDRINAAVLMIVTATLGETFVAMQAFEWSKLILEEGVRPWGNPMGAAQFGSAFFMITGFH
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCEEEEEECCC
GLHVTAGVIYLLVVATRLLRGRYEQSGNYQIVEIVGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDTTIPMASPPSAAVSAASAGVGWRGLVSDWSSDREAFHVSWGKAMMWIFLLSDTFIFSC
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
FLTGYMTVRVSTTVPWPNPSQVFALHVGGTEVPLLLIAIMTFVLISSSGTMAMAVNCAYR
HHHCEEEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
RDRINAAVLMIVTATLGETFVAMQAFEWSKLILEEGVRPWGNPMGAAQFGSAFFMITGFH
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCEEEEEECCC
GLHVTAGVIYLLVVATRLLRGRYEQSGNYQIVEIVGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ubiquinol-8; O(2) [C]

Specific reaction: Ubiquinol-8 + O(2) = Ubiquinone-8 + H2O. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]