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The map label for this gene is cya1 [H]

Identifier: 91786623

GI number: 91786623

Start: 734422

End: 736611

Strand: Reverse

Name: cya1 [H]

Synonym: Bpro_0721

Alternate gene names: 91786623

Gene position: 736611-734422 (Counterclockwise)

Preceding gene: 91786624

Following gene: 91786617

Centisome position: 14.16

GC content: 65.25

Gene sequence:

>2190_bases
ATGTTCCGAGGCTTATCGTTACGCAGGCTTCCCGGTGTTTTGTCCAATGCCGCGGCAGTCACGCTGGTGCTGTTGATTGC
CCTGAGCGGATTGGCACTGTGGTTCACCGATCCGATACCGGTGCAGAGCCTGCGGCTGGCACAGTTTGACCAGTTCCAGC
GCTGGCATCCACGCCCCTATACGCCAGCGGCCGTGCGTGTGGTGGACATTGATGAGGCCAGCCTGAAAGCCTACGGCCAA
TGGCCCTGGCCACGAACCCGCCTGGCCGAACTGGTACAGCGTCTGGATGAGGCCGGCACGGCAGCCATCGCCTTTGACGT
GCTGCTGACCGAGCCGGATCGCACCTCGCCGGCGGCCATGGCACAACTCTGGAACAACCCGAGGGTCGGCGCCGCGCTGC
AGCGGCTCCCCGACCATGACGAGGTTCTGGGCAAAATGCTGGACGGCCGGAACGTGGTGCTGGGCAGCAGCCTGTCCCGA
AGCGGCGAGGCCAACGCATCCGCGGCGCCCGCCGCCAACGTCCCCTCCGCACTGCCCTACCGCATTGTGAGCAGCGGCGC
CAGCAATCCGGCGCAATGGCTTCACGGCTTTGACATCGGGCTCTGGCCATTGCCGGTGTTGCAGAGCGGTGCAGCCGGAC
TGGGTGCGCTGAATTTTGCGGCGGACGCCGATGGTGTGGTGCGCCGGGTACCCCTGCTGTTGCGCCTGGGCCAGCAGATT
GTGCCCACCTTGAGCGCCGAGGCCCTGCGTGTCGCTCAGGGTGAGCGCAACCACCTGCTGCGCAGTACCGAGGCCGGCGT
GCAGGACGTGCGCATCGGCGGCGTCACCGTGCCCACCAATGCGCAGGCCGAAATCTGGCTTCACTACACGGAGGATCAAC
CCGATCGCTTCGTGTCAGCGGCCCAGGTGCTGGGCAGAAAGACCGACAGAAAACTGCTGGACGGACACATCGTGCTGATC
GGCAGTTCGGCTGCCGGGTTGATGGATTTGCGCTTCAACCCGATGGGAAGGATGATGCCTGGCGTTCAGGCCCACGCGCT
GGCGCTGGAGCAGGTGTTGTCGAATCAGTATCTGCAGCGACCCGCCTGGGCCGGCGGGGTCGAGGTGCTCACGCTGGTGC
TGGGCTCCCTGGTCGTCGGCCTGCTGGCGCTGGGCACTCCCGCCAAGTGGGCAACCCTGGCGGCAGTCGGGGTGCTGGCC
GCCCTGTTCGGCGGCGCCTGGTATGCGTTCGTGGCCGAACACCTGCTGCTCGATGCGATCAATCCCGGACTGGTCATCCT
GGTGAGCTTCGGTCTGGCCAGCGGTATGCACCATCTGGTCAGTGAACGTGAACAGCGCTGGGTACGCCAGGCTTTTTCAC
GCTATGTGTCGCCCAACAGGGTGGCGCATCTGGTGGCGCACCGGGAACAGCTGGAACTGGGGGGCCAGCGCCAGGTCTGC
AGCTTCGTCTTTACCGACCTAGCGGGCTTTACCAGCATGATGGAAGCTGACGACCCGAGCCGGGCGGTGGCCCTGCTCAA
CGATTATCTGGACGCCATGCTCGCCATCGTCTTCAAGCACGAAGGCACGCTGGACCGCATCGTGGGCGACGCGGTGGCCG
TGCTGTTTTCGGCGCCGGTGCAGCAAGCCGATCATCGCCAGCGCGCCCTCAACTGCGTGCTGGAGATGGACACCTTTGCG
TCAGCCTACGCGGCCCGGCTGCAGGCTCAGGGCATTCCCTGGGGACACACCCGTATCGGCAGCCACAGTGGCGAGGTGAT
CGTCGGCAATTTTGGCGGCAAGACGCTGTTTGACTACCGGGCGCTGGGTGACCCGATCAATACCGCAGCACGGCTGGAGA
CCGTCAACAAGCACCTGGGCACGCGCGTCTGCGTGTCACAGGCCATTCTGGATGGCTGTACGGATGTGCCAGTGCGGCGC
GTCGGGCAGCTGGTGCTCAAAGGCAAGAGCAAACCGCTGTTGGTGTTTGAGCCGCTGGCCACCACCAATGCCGCCAACTG
CGCCGCCCCCGCCGACTATGACGCGGCGATGCGCCTGCTGCAACCCGGCGAGATGCATCACCCGACACTCGCCTGTGAAT
ATTTTGAGGCCCTGGCCGAACGCCACCCGGATGACCCGCTGGTGGCGCTGCACCTTCGCAGGCTGCGCGAGGGTGCTGCA
GATGACCTCATCGTGATGACCGAGAAGTGA

Upstream 100 bases:

>100_bases
CGGACAATCGACATCGCCTTTCGAACACCCCTCGATATAAACCGCCTGTTATCCGGGTCCGCCCCACATAATAGGCGGCA
ACGTCCCACAGGAATCGACC

Downstream 100 bases:

>100_bases
AGTCCCCCGTCAGCGCACCGTTATCTCTGCCCGGCGGTTACGCGGCTCATTGGTATTTTGAGGTGTAGCCACGAAAAGAT
TGCGCTCGCCGTTGGACTCC

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1 [H]

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MFRGLSLRRLPGVLSNAAAVTLVLLIALSGLALWFTDPIPVQSLRLAQFDQFQRWHPRPYTPAAVRVVDIDEASLKAYGQ
WPWPRTRLAELVQRLDEAGTAAIAFDVLLTEPDRTSPAAMAQLWNNPRVGAALQRLPDHDEVLGKMLDGRNVVLGSSLSR
SGEANASAAPAANVPSALPYRIVSSGASNPAQWLHGFDIGLWPLPVLQSGAAGLGALNFAADADGVVRRVPLLLRLGQQI
VPTLSAEALRVAQGERNHLLRSTEAGVQDVRIGGVTVPTNAQAEIWLHYTEDQPDRFVSAAQVLGRKTDRKLLDGHIVLI
GSSAAGLMDLRFNPMGRMMPGVQAHALALEQVLSNQYLQRPAWAGGVEVLTLVLGSLVVGLLALGTPAKWATLAAVGVLA
ALFGGAWYAFVAEHLLLDAINPGLVILVSFGLASGMHHLVSEREQRWVRQAFSRYVSPNRVAHLVAHREQLELGGQRQVC
SFVFTDLAGFTSMMEADDPSRAVALLNDYLDAMLAIVFKHEGTLDRIVGDAVAVLFSAPVQQADHRQRALNCVLEMDTFA
SAYAARLQAQGIPWGHTRIGSHSGEVIVGNFGGKTLFDYRALGDPINTAARLETVNKHLGTRVCVSQAILDGCTDVPVRR
VGQLVLKGKSKPLLVFEPLATTNAANCAAPADYDAAMRLLQPGEMHHPTLACEYFEALAERHPDDPLVALHLRRLREGAA
DDLIVMTEK

Sequences:

>Translated_729_residues
MFRGLSLRRLPGVLSNAAAVTLVLLIALSGLALWFTDPIPVQSLRLAQFDQFQRWHPRPYTPAAVRVVDIDEASLKAYGQ
WPWPRTRLAELVQRLDEAGTAAIAFDVLLTEPDRTSPAAMAQLWNNPRVGAALQRLPDHDEVLGKMLDGRNVVLGSSLSR
SGEANASAAPAANVPSALPYRIVSSGASNPAQWLHGFDIGLWPLPVLQSGAAGLGALNFAADADGVVRRVPLLLRLGQQI
VPTLSAEALRVAQGERNHLLRSTEAGVQDVRIGGVTVPTNAQAEIWLHYTEDQPDRFVSAAQVLGRKTDRKLLDGHIVLI
GSSAAGLMDLRFNPMGRMMPGVQAHALALEQVLSNQYLQRPAWAGGVEVLTLVLGSLVVGLLALGTPAKWATLAAVGVLA
ALFGGAWYAFVAEHLLLDAINPGLVILVSFGLASGMHHLVSEREQRWVRQAFSRYVSPNRVAHLVAHREQLELGGQRQVC
SFVFTDLAGFTSMMEADDPSRAVALLNDYLDAMLAIVFKHEGTLDRIVGDAVAVLFSAPVQQADHRQRALNCVLEMDTFA
SAYAARLQAQGIPWGHTRIGSHSGEVIVGNFGGKTLFDYRALGDPINTAARLETVNKHLGTRVCVSQAILDGCTDVPVRR
VGQLVLKGKSKPLLVFEPLATTNAANCAAPADYDAAMRLLQPGEMHHPTLACEYFEALAERHPDDPLVALHLRRLREGAA
DDLIVMTEK
>Mature_729_residues
MFRGLSLRRLPGVLSNAAAVTLVLLIALSGLALWFTDPIPVQSLRLAQFDQFQRWHPRPYTPAAVRVVDIDEASLKAYGQ
WPWPRTRLAELVQRLDEAGTAAIAFDVLLTEPDRTSPAAMAQLWNNPRVGAALQRLPDHDEVLGKMLDGRNVVLGSSLSR
SGEANASAAPAANVPSALPYRIVSSGASNPAQWLHGFDIGLWPLPVLQSGAAGLGALNFAADADGVVRRVPLLLRLGQQI
VPTLSAEALRVAQGERNHLLRSTEAGVQDVRIGGVTVPTNAQAEIWLHYTEDQPDRFVSAAQVLGRKTDRKLLDGHIVLI
GSSAAGLMDLRFNPMGRMMPGVQAHALALEQVLSNQYLQRPAWAGGVEVLTLVLGSLVVGLLALGTPAKWATLAAVGVLA
ALFGGAWYAFVAEHLLLDAINPGLVILVSFGLASGMHHLVSEREQRWVRQAFSRYVSPNRVAHLVAHREQLELGGQRQVC
SFVFTDLAGFTSMMEADDPSRAVALLNDYLDAMLAIVFKHEGTLDRIVGDAVAVLFSAPVQQADHRQRALNCVLEMDTFA
SAYAARLQAQGIPWGHTRIGSHSGEVIVGNFGGKTLFDYRALGDPINTAARLETVNKHLGTRVCVSQAILDGCTDVPVRR
VGQLVLKGKSKPLLVFEPLATTNAANCAAPADYDAAMRLLQPGEMHHPTLACEYFEALAERHPDDPLVALHLRRLREGAA
DDLIVMTEK

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71989805, Length=210, Percent_Identity=28.0952380952381, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 78745; Mature: 78745

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRGLSLRRLPGVLSNAAAVTLVLLIALSGLALWFTDPIPVQSLRLAQFDQFQRWHPRPY
CCCCCCHHHHCHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCCC
TPAAVRVVDIDEASLKAYGQWPWPRTRLAELVQRLDEAGTAAIAFDVLLTEPDRTSPAAM
CCCEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHH
AQLWNNPRVGAALQRLPDHDEVLGKMLDGRNVVLGSSLSRSGEANASAAPAANVPSALPY
HHHHCCCCCCHHHHHCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCH
RIVSSGASNPAQWLHGFDIGLWPLPVLQSGAAGLGALNFAADADGVVRRVPLLLRLGQQI
HHHHCCCCCHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VPTLSAEALRVAQGERNHLLRSTEAGVQDVRIGGVTVPTNAQAEIWLHYTEDQPDRFVSA
HHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCEECCCCCCEEEEEEECCCCHHHHHHH
AQVLGRKTDRKLLDGHIVLIGSSAAGLMDLRFNPMGRMMPGVQAHALALEQVLSNQYLQR
HHHHCCHHCHHHHCCEEEEEECCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHCC
PAWAGGVEVLTLVLGSLVVGLLALGTPAKWATLAAVGVLAALFGGAWYAFVAEHLLLDAI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPGLVILVSFGLASGMHHLVSEREQRWVRQAFSRYVSPNRVAHLVAHREQLELGGQRQVC
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
SFVFTDLAGFTSMMEADDPSRAVALLNDYLDAMLAIVFKHEGTLDRIVGDAVAVLFSAPV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QQADHRQRALNCVLEMDTFASAYAARLQAQGIPWGHTRIGSHSGEVIVGNFGGKTLFDYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEHHHH
ALGDPINTAARLETVNKHLGTRVCVSQAILDGCTDVPVRRVGQLVLKGKSKPLLVFEPLA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCC
TTNAANCAAPADYDAAMRLLQPGEMHHPTLACEYFEALAERHPDDPLVALHLRRLREGAA
CCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
DDLIVMTEK
CCEEEEECC
>Mature Secondary Structure
MFRGLSLRRLPGVLSNAAAVTLVLLIALSGLALWFTDPIPVQSLRLAQFDQFQRWHPRPY
CCCCCCHHHHCHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCCC
TPAAVRVVDIDEASLKAYGQWPWPRTRLAELVQRLDEAGTAAIAFDVLLTEPDRTSPAAM
CCCEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHH
AQLWNNPRVGAALQRLPDHDEVLGKMLDGRNVVLGSSLSRSGEANASAAPAANVPSALPY
HHHHCCCCCCHHHHHCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCH
RIVSSGASNPAQWLHGFDIGLWPLPVLQSGAAGLGALNFAADADGVVRRVPLLLRLGQQI
HHHHCCCCCHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VPTLSAEALRVAQGERNHLLRSTEAGVQDVRIGGVTVPTNAQAEIWLHYTEDQPDRFVSA
HHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCEECCCCCCEEEEEEECCCCHHHHHHH
AQVLGRKTDRKLLDGHIVLIGSSAAGLMDLRFNPMGRMMPGVQAHALALEQVLSNQYLQR
HHHHCCHHCHHHHCCEEEEEECCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHCC
PAWAGGVEVLTLVLGSLVVGLLALGTPAKWATLAAVGVLAALFGGAWYAFVAEHLLLDAI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPGLVILVSFGLASGMHHLVSEREQRWVRQAFSRYVSPNRVAHLVAHREQLELGGQRQVC
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
SFVFTDLAGFTSMMEADDPSRAVALLNDYLDAMLAIVFKHEGTLDRIVGDAVAVLFSAPV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QQADHRQRALNCVLEMDTFASAYAARLQAQGIPWGHTRIGSHSGEVIVGNFGGKTLFDYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEHHHH
ALGDPINTAARLETVNKHLGTRVCVSQAILDGCTDVPVRRVGQLVLKGKSKPLLVFEPLA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCC
TTNAANCAAPADYDAAMRLLQPGEMHHPTLACEYFEALAERHPDDPLVALHLRRLREGAA
CCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
DDLIVMTEK
CCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 1970565 [H]