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The map label for this gene is glcD [H]

Identifier: 91786343

GI number: 91786343

Start: 448530

End: 450032

Strand: Reverse

Name: glcD [H]

Synonym: Bpro_0433

Alternate gene names: 91786343

Gene position: 450032-448530 (Counterclockwise)

Preceding gene: 91786344

Following gene: 91786342

Centisome position: 8.65

GC content: 63.87

Gene sequence:

>1503_bases
ATGAACGCCCCCTTATCTCCCCCGCAGCACGATTTACATGAAAGAGCCGAGCGCCAGTCGCACGTGGTGCAGGCGCTTCA
AGCCGTGCTGCCCGCCCACGCCCTGCTCTGGAACAGCGAAGACACCACACCCTATGAATGTGACGGTCTGACGGCTTATC
GCCAGCGCCCGCTGGTGGTGGCCCTGCCCGAAACCTATGCGCAGGTGCAGGCCGTGCTGCAAACCTGCCACAGCCTTGAG
GTGCCGGTGGTGGCGCGCGGCGCCGGCACCGGCCTTTCCGGCGGCGCGATGCCGCACCGGCTGGGTGTCACGCTGTCGCT
GGCCAAGTTCAACAAAATCCTGAAGCTCGACCCCACCAGCCGCACCGCCGTCGTGCAGGGCGGTGTGCGCAACCTGGCGA
TCTCCGAAGCGGCAGCGCCCTGCGGCCTCTATTACGCACCCGACCCGTCAAGCCAGATTGCCTGCACCATCGGCGGCAAC
GTGGCCGAGAATTCCGGCGGCGTGCACTGCCTCAAGTACGGGCTCACCGTGCACAACGTGCTCAAGGTCAAGGGCTTCAC
CATCACCGGGGAAGAAGTCGAATTTGGCAGTGACGCGCTGGATGCGTCGGGCTACGACCTGCTGAGCATCATCATCGGCA
GCGAAGGCATGCTGGCCGTGACGACCGAGGTCACCGTCAAGCTTGTGCCCAAACCGCAGCTGGCGCGCTGCATCATGGCC
AGCTTTGACGATCTGCGCAAAGCCGGTGATGCGGTGGCGGCGGTCATTGCGGCCGGCATCATCCCGGCGGGGCTGGAGAT
GATGGACAAGCCCATGACGGCTGCCGTGGAAGATTTTGTGCATGCGGGCTACGACCTGAGCGCCGAAGCGATTTTGCTGT
GCGAGAGCGATGGCACACCCGAGGAAGTCGAGGAAGAGATCGGCCGCATGAGCGAGGTGCTGCGCCGCTGCGGCGCCACC
GCCATTGCCGTGAGCCAGAATGAGGCCGAGCGCCTGCGCTTCTGGAGCGGACGCAAGAATGCCTTCCCCGCGTCCGGCCG
CATCAGCCCCGACTACATGTGCATGGACTCCACCATTCCGCGCAAGCGTCTGGCCGACATCCTGCTCGCGATCCAGGACA
TGGAAAAGAAATACCAGCTGCGTTGCGCCAATGTGTTTCATGCCGGCGACGGCAACCTGCACCCGCTGATTTTGTTTGAC
GCCAACGACGCCGACCAGTTGCACCGCTGCGAGTTGTTCGGGGCCGACATTCTTGAAACCAGCGTCGCCATGGGCGGCAC
CATCACCGGCGAGCACGGCGTTGGCGTGGAGAAACTCAACTCCATGTGCGTGCAATTTTCCGCGGAAGAAAACGAGCAGA
TGTTTGGCGTCAAGCGTGCCTTCGATGCCAGGGGCCTGCTCAACCCCGGCAAGGTCATCCCCACGCTGAACCGCTGCGCC
GAGTACGGAAAAATGCTGGTGCGTGGCGGCCAGATCGCGCATCCGGACCTGCCGCGTTTCTGA

Upstream 100 bases:

>100_bases
CACTGCGCCCACAAATCCGGCATTTCACGCAAGACCATAAATTTCTTCAACCCAACCGGCGCTGCATGCTCTAAAGTTTG
ACCTCAGACAGGAGCCCCGC

Downstream 100 bases:

>100_bases
CAATCACGAAGCACCAGGAAGCGCACTCAGCATGCAAGCCCTCCGCGGACTGGCCTGGCTGCTGGCACTTCAGTCCATCG
GTGAGTTGCTGACGCGCGGG

Product: FAD linked oxidase-like protein

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MNAPLSPPQHDLHERAERQSHVVQALQAVLPAHALLWNSEDTTPYECDGLTAYRQRPLVVALPETYAQVQAVLQTCHSLE
VPVVARGAGTGLSGGAMPHRLGVTLSLAKFNKILKLDPTSRTAVVQGGVRNLAISEAAAPCGLYYAPDPSSQIACTIGGN
VAENSGGVHCLKYGLTVHNVLKVKGFTITGEEVEFGSDALDASGYDLLSIIIGSEGMLAVTTEVTVKLVPKPQLARCIMA
SFDDLRKAGDAVAAVIAAGIIPAGLEMMDKPMTAAVEDFVHAGYDLSAEAILLCESDGTPEEVEEEIGRMSEVLRRCGAT
AIAVSQNEAERLRFWSGRKNAFPASGRISPDYMCMDSTIPRKRLADILLAIQDMEKKYQLRCANVFHAGDGNLHPLILFD
ANDADQLHRCELFGADILETSVAMGGTITGEHGVGVEKLNSMCVQFSAEENEQMFGVKRAFDARGLLNPGKVIPTLNRCA
EYGKMLVRGGQIAHPDLPRF

Sequences:

>Translated_500_residues
MNAPLSPPQHDLHERAERQSHVVQALQAVLPAHALLWNSEDTTPYECDGLTAYRQRPLVVALPETYAQVQAVLQTCHSLE
VPVVARGAGTGLSGGAMPHRLGVTLSLAKFNKILKLDPTSRTAVVQGGVRNLAISEAAAPCGLYYAPDPSSQIACTIGGN
VAENSGGVHCLKYGLTVHNVLKVKGFTITGEEVEFGSDALDASGYDLLSIIIGSEGMLAVTTEVTVKLVPKPQLARCIMA
SFDDLRKAGDAVAAVIAAGIIPAGLEMMDKPMTAAVEDFVHAGYDLSAEAILLCESDGTPEEVEEEIGRMSEVLRRCGAT
AIAVSQNEAERLRFWSGRKNAFPASGRISPDYMCMDSTIPRKRLADILLAIQDMEKKYQLRCANVFHAGDGNLHPLILFD
ANDADQLHRCELFGADILETSVAMGGTITGEHGVGVEKLNSMCVQFSAEENEQMFGVKRAFDARGLLNPGKVIPTLNRCA
EYGKMLVRGGQIAHPDLPRF
>Mature_500_residues
MNAPLSPPQHDLHERAERQSHVVQALQAVLPAHALLWNSEDTTPYECDGLTAYRQRPLVVALPETYAQVQAVLQTCHSLE
VPVVARGAGTGLSGGAMPHRLGVTLSLAKFNKILKLDPTSRTAVVQGGVRNLAISEAAAPCGLYYAPDPSSQIACTIGGN
VAENSGGVHCLKYGLTVHNVLKVKGFTITGEEVEFGSDALDASGYDLLSIIIGSEGMLAVTTEVTVKLVPKPQLARCIMA
SFDDLRKAGDAVAAVIAAGIIPAGLEMMDKPMTAAVEDFVHAGYDLSAEAILLCESDGTPEEVEEEIGRMSEVLRRCGAT
AIAVSQNEAERLRFWSGRKNAFPASGRISPDYMCMDSTIPRKRLADILLAIQDMEKKYQLRCANVFHAGDGNLHPLILFD
ANDADQLHRCELFGADILETSVAMGGTITGEHGVGVEKLNSMCVQFSAEENEQMFGVKRAFDARGLLNPGKVIPTLNRCA
EYGKMLVRGGQIAHPDLPRF

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=423, Percent_Identity=28.6052009456265, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI37595754, Length=446, Percent_Identity=27.8026905829596, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI119964728, Length=435, Percent_Identity=26.2068965517241, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI4501993, Length=221, Percent_Identity=24.4343891402715, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1789351, Length=482, Percent_Identity=60.1659751037344, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1787977, Length=518, Percent_Identity=22.972972972973, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71992373, Length=427, Percent_Identity=26.2295081967213, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71992381, Length=427, Percent_Identity=24.5901639344262, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71992392, Length=359, Percent_Identity=25.0696378830084, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534361, Length=447, Percent_Identity=26.3982102908277, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17556096, Length=423, Percent_Identity=22.2222222222222, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320027, Length=433, Percent_Identity=26.0969976905312, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320023, Length=453, Percent_Identity=28.0353200883002, Blast_Score=150, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6320764, Length=455, Percent_Identity=25.2747252747253, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI18921117, Length=445, Percent_Identity=26.9662921348315, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24639277, Length=445, Percent_Identity=26.9662921348315, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24639275, Length=445, Percent_Identity=26.9662921348315, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24653753, Length=221, Percent_Identity=26.6968325791855, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.3.15

Molecular weight: Translated: 53646; Mature: 53646

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLSPPQHDLHERAERQSHVVQALQAVLPAHALLWNSEDTTPYECDGLTAYRQRPLVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHCCCEEE
ALPETYAQVQAVLQTCHSLEVPVVARGAGTGLSGGAMPHRLGVTLSLAKFNKILKLDPTS
ECCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHCCEEEHHHCCCEEEECCCC
RTAVVQGGVRNLAISEAAAPCGLYYAPDPSSQIACTIGGNVAENSGGVHCLKYGLTVHNV
CEEEEECCHHHHHHHHHCCCCCEEECCCCCCCEEEEECCCEECCCCCEEEEEECCHHHHE
LKVKGFTITGEEVEFGSDALDASGYDLLSIIIGSEGMLAVTTEVTVKLVPKPQLARCIMA
EEEECEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHH
SFDDLRKAGDAVAAVIAAGIIPAGLEMMDKPMTAAVEDFVHAGYDLSAEAILLCESDGTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCH
EEVEEEIGRMSEVLRRCGATAIAVSQNEAERLRFWSGRKNAFPASGRISPDYMCMDSTIP
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCC
RKRLADILLAIQDMEKKYQLRCANVFHAGDGNLHPLILFDANDADQLHRCELFGADILET
HHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHH
SVAMGGTITGEHGVGVEKLNSMCVQFSAEENEQMFGVKRAFDARGLLNPGKVIPTLNRCA
HHHCCCEECCCCCCCHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
EYGKMLVRGGQIAHPDLPRF
HHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNAPLSPPQHDLHERAERQSHVVQALQAVLPAHALLWNSEDTTPYECDGLTAYRQRPLVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHCCCEEE
ALPETYAQVQAVLQTCHSLEVPVVARGAGTGLSGGAMPHRLGVTLSLAKFNKILKLDPTS
ECCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHCCEEEHHHCCCEEEECCCC
RTAVVQGGVRNLAISEAAAPCGLYYAPDPSSQIACTIGGNVAENSGGVHCLKYGLTVHNV
CEEEEECCHHHHHHHHHCCCCCEEECCCCCCCEEEEECCCEECCCCCEEEEEECCHHHHE
LKVKGFTITGEEVEFGSDALDASGYDLLSIIIGSEGMLAVTTEVTVKLVPKPQLARCIMA
EEEECEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHH
SFDDLRKAGDAVAAVIAAGIIPAGLEMMDKPMTAAVEDFVHAGYDLSAEAILLCESDGTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCH
EEVEEEIGRMSEVLRRCGATAIAVSQNEAERLRFWSGRKNAFPASGRISPDYMCMDSTIP
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCC
RKRLADILLAIQDMEKKYQLRCANVFHAGDGNLHPLILFDANDADQLHRCELFGADILET
HHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHH
SVAMGGTITGEHGVGVEKLNSMCVQFSAEENEQMFGVKRAFDARGLLNPGKVIPTLNRCA
HHHCCCEECCCCCCCHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
EYGKMLVRGGQIAHPDLPRF
HHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]