Click here to switch to the map view.

The map label for this gene is cidA1 [H]

Identifier: 91786342

GI number: 91786342

Start: 448127

End: 448498

Strand: Reverse

Name: cidA1 [H]

Synonym: Bpro_0432

Alternate gene names: 91786342

Gene position: 448498-448127 (Counterclockwise)

Preceding gene: 91786343

Following gene: 91786341

Centisome position: 8.62

GC content: 62.1

Gene sequence:

>372_bases
ATGCAAGCCCTCCGCGGACTGGCCTGGCTGCTGGCACTTCAGTCCATCGGTGAGTTGCTGACGCGCGGGTTGTCTTTGCC
CTTTCCGGGGCCCGTCATTGGCATGATGTTGCTGCTCCCGGCGTTGCGATGGCGCATGGTGCGCGAGCCGGTTTCTGCCT
GTGCAGACTTTTTGCTGACACACCTTTCGTTACTCTTTGTACCCGTCGGCGTCGGTGTGATGACGCATCTCTCACTCGTC
AGCCAGTATGGCGTGCGCATGCTCGCAGTCATTGTGCTGTCCACGCTGGCCGGTCTGGCGGTGACTGTTTTGAGCCTGCA
CCTGCTGCAGGGCCGCCTCGACCCCCTCGGGAAGGAGGACCCGCATGCCTAA

Upstream 100 bases:

>100_bases
TGCGCCGAGTACGGAAAAATGCTGGTGCGTGGCGGCCAGATCGCGCATCCGGACCTGCCGCGTTTCTGACAATCACGAAG
CACCAGGAAGCGCACTCAGC

Downstream 100 bases:

>100_bases
GTTCGTGGAGCTGTGGGTCTACCTCTCGGCCTCGCCGCTGTTCGGACTGACTGCCACGCTGGTGGTGTATGTGCTGGCCC
AGGCAGCGTATGCGCGCCTG

Product: LrgA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MQALRGLAWLLALQSIGELLTRGLSLPFPGPVIGMMLLLPALRWRMVREPVSACADFLLTHLSLLFVPVGVGVMTHLSLV
SQYGVRMLAVIVLSTLAGLAVTVLSLHLLQGRLDPLGKEDPHA

Sequences:

>Translated_123_residues
MQALRGLAWLLALQSIGELLTRGLSLPFPGPVIGMMLLLPALRWRMVREPVSACADFLLTHLSLLFVPVGVGVMTHLSLV
SQYGVRMLAVIVLSTLAGLAVTVLSLHLLQGRLDPLGKEDPHA
>Mature_123_residues
MQALRGLAWLLALQSIGELLTRGLSLPFPGPVIGMMLLLPALRWRMVREPVSACADFLLTHLSLLFVPVGVGVMTHLSLV
SQYGVRMLAVIVLSTLAGLAVTVLSLHLLQGRLDPLGKEDPHA

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 13241; Mature: 13241

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALRGLAWLLALQSIGELLTRGLSLPFPGPVIGMMLLLPALRWRMVREPVSACADFLLT
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLSLLFVPVGVGVMTHLSLVSQYGVRMLAVIVLSTLAGLAVTVLSLHLLQGRLDPLGKED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PHA
CCC
>Mature Secondary Structure
MQALRGLAWLLALQSIGELLTRGLSLPFPGPVIGMMLLLPALRWRMVREPVSACADFLLT
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLSLLFVPVGVGVMTHLSLVSQYGVRMLAVIVLSTLAGLAVTVLSLHLLQGRLDPLGKED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PHA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]