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The map label for this gene is insK [C]

Identifier: 91786250

GI number: 91786250

Start: 360199

End: 361746

Strand: Reverse

Name: insK [C]

Synonym: Bpro_0339

Alternate gene names: 91786250

Gene position: 361746-360199 (Counterclockwise)

Preceding gene: 91786254

Following gene: 91786249

Centisome position: 6.96

GC content: 55.17

Gene sequence:

>1548_bases
ATGTATTCATACGAAGATCGCATTCGAGCAGTTAGGCTCTACATAAAACTCGGGAAACGCACAGGTGCGACCATTCGGCA
ATTGGGTTACCCGACAAAGAATGCGCTTAAGAGCTGGCATCGAGAATACGAGCAAGGTGGCAATTTGCGGGTGGGCCATG
TGCGTTCAAGATCAAAATACTCAGCCGAACAGAAAAGAGTTGCCGTCGAGCATTACCTAAACCACGATCGCTTTCTTGCT
GGAACTCGAAAAGCACTGGGATATCCGTGCCGCGATACTCTCGCAGCCTGGGTCCACGAGTTGCTCCCCGAAACACGAAG
AAAAGTTGTCGGCAAGGCGCAGGCCGTGCTGCTCCCCAGAGAAGCAAAGCAGGCGGCAGTCATCGAGCTGTGCACTCGGC
AGGTAAGCGCGCAAGCAATTGCTCAAAAGCTTGGCGTGACTCGACCAACGTTGTACAAGTGGAAAAATCAACTACTCGGT
CGAGAGGCTCCCGCATCCATGAAGCGAAGTAACGATTCCGGGTCAACTCCCAAGCCGAAAGAACTCACGGAACTACAGCA
GCAAGTTGAGTTGCTCGAACGTGACATCCGGCGTTTGCAGCTTGAACATGACCTATTAAAGAAGGCCAATGAACTGTTAA
AAAAAGGCCTGGGCGTCGATATGCAACTCCTGACCAACCGGGAGAAGACATTGCTGGTTGACGCCCTCAAAGAGCTCTAT
GCCCTGCCAGAGCTCCTTGCTCAGTTGGATCTGGCGCGCAGCTCGTACTTCTACCATCGAGCCCGTGTAAAGATGGCGGA
CAAGTACCTTGCAGTGCGGCAAACCCTCACCGACATCTTCGAGCTGAACCACCGCTGTTACGGCTACCGCAGGCTGCAGG
CTTCGTTGACCAGGCAGTGCGTCACCATCTCTGAGAAGGTCGTGCAGCGGTTGATGAAACAAGAGAGCTTGGTCGTTGCC
AAGCCTAAGCGGCGTCGGTACGGCTCCTACTTGGGCGAAATCAGCCCAGCGCCCGAGAACCTCATCAATCGCGACTTCCA
CGCAGCGGCCCCGAACGAGAAGTGGCTCACCGACATCACAGAGTTCCAGATCCCGGCCGGCAAGGTGTACCTATCGCCCA
TCATCGACTGCTTCGATGGCCTGGTCATCAGCTGGACCATTGGGACGCATCCCGACGCTGAGCTCGTCAACACGATGCTG
GATGCAGCCATCGAGACGGTGGCCGGCGGCAATGACCGGCCCGTCGTCCACTCTGATCGTGGAGCACACTATCGCTGGCC
CGGTTGGCTATCGAGGATCGGTGACGCGAAGTTGATTCGCTCGATGTCGCGCAAGGGGTGTTCGCCTGACAACGCGGCCT
GCGAGGGTTTCTTCGGGCGATTGAAAACGGAACTGTTCTACCCTCGGGACTGGAAGACCACAACCATTGAACAGTTCATT
CAGGTAGTCGATTCCTACATCCGCTGGTACAACGAGAAGCGGATCAAGATATCTCTTGGCTCTCTTAGCCCCATCGAATA
CCGAGAGAGTCTTGGACTTACGGCATAA

Upstream 100 bases:

>100_bases
AACCGTTGCCTGCAGTGGGATTGCGAGGTAATGTCCTGGGTCAGTGCGAAGTCGGAACCTGGGGGTGCGGACAAAAACTT
GGACTACTTGGAGGTAGTTC

Downstream 100 bases:

>100_bases
ACCAGTCCAAGTTTTCATCCGCACCCCCACCTGATCAATTTGGTGTCGGCGCCAACAGGATGACCACAGACGGCAGTGAA
CGCCGCGTTGAACGTCCTCT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MYSYEDRIRAVRLYIKLGKRTGATIRQLGYPTKNALKSWHREYEQGGNLRVGHVRSRSKYSAEQKRVAVEHYLNHDRFLA
GTRKALGYPCRDTLAAWVHELLPETRRKVVGKAQAVLLPREAKQAAVIELCTRQVSAQAIAQKLGVTRPTLYKWKNQLLG
REAPASMKRSNDSGSTPKPKELTELQQQVELLERDIRRLQLEHDLLKKANELLKKGLGVDMQLLTNREKTLLVDALKELY
ALPELLAQLDLARSSYFYHRARVKMADKYLAVRQTLTDIFELNHRCYGYRRLQASLTRQCVTISEKVVQRLMKQESLVVA
KPKRRRYGSYLGEISPAPENLINRDFHAAAPNEKWLTDITEFQIPAGKVYLSPIIDCFDGLVISWTIGTHPDAELVNTML
DAAIETVAGGNDRPVVHSDRGAHYRWPGWLSRIGDAKLIRSMSRKGCSPDNAACEGFFGRLKTELFYPRDWKTTTIEQFI
QVVDSYIRWYNEKRIKISLGSLSPIEYRESLGLTA

Sequences:

>Translated_515_residues
MYSYEDRIRAVRLYIKLGKRTGATIRQLGYPTKNALKSWHREYEQGGNLRVGHVRSRSKYSAEQKRVAVEHYLNHDRFLA
GTRKALGYPCRDTLAAWVHELLPETRRKVVGKAQAVLLPREAKQAAVIELCTRQVSAQAIAQKLGVTRPTLYKWKNQLLG
REAPASMKRSNDSGSTPKPKELTELQQQVELLERDIRRLQLEHDLLKKANELLKKGLGVDMQLLTNREKTLLVDALKELY
ALPELLAQLDLARSSYFYHRARVKMADKYLAVRQTLTDIFELNHRCYGYRRLQASLTRQCVTISEKVVQRLMKQESLVVA
KPKRRRYGSYLGEISPAPENLINRDFHAAAPNEKWLTDITEFQIPAGKVYLSPIIDCFDGLVISWTIGTHPDAELVNTML
DAAIETVAGGNDRPVVHSDRGAHYRWPGWLSRIGDAKLIRSMSRKGCSPDNAACEGFFGRLKTELFYPRDWKTTTIEQFI
QVVDSYIRWYNEKRIKISLGSLSPIEYRESLGLTA
>Mature_515_residues
MYSYEDRIRAVRLYIKLGKRTGATIRQLGYPTKNALKSWHREYEQGGNLRVGHVRSRSKYSAEQKRVAVEHYLNHDRFLA
GTRKALGYPCRDTLAAWVHELLPETRRKVVGKAQAVLLPREAKQAAVIELCTRQVSAQAIAQKLGVTRPTLYKWKNQLLG
REAPASMKRSNDSGSTPKPKELTELQQQVELLERDIRRLQLEHDLLKKANELLKKGLGVDMQLLTNREKTLLVDALKELY
ALPELLAQLDLARSSYFYHRARVKMADKYLAVRQTLTDIFELNHRCYGYRRLQASLTRQCVTISEKVVQRLMKQESLVVA
KPKRRRYGSYLGEISPAPENLINRDFHAAAPNEKWLTDITEFQIPAGKVYLSPIIDCFDGLVISWTIGTHPDAELVNTML
DAAIETVAGGNDRPVVHSDRGAHYRWPGWLSRIGDAKLIRSMSRKGCSPDNAACEGFFGRLKTELFYPRDWKTTTIEQFI
QVVDSYIRWYNEKRIKISLGSLSPIEYRESLGLTA

Specific function: Probably involved in the transposition of insertion sequence IS1353 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=265, Percent_Identity=26.7924528301887, Blast_Score=92, Evalue=2e-18,
Organism=Escherichia coli, GI1789981, Length=277, Percent_Identity=41.1552346570397, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1788405, Length=294, Percent_Identity=28.2312925170068, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787263, Length=294, Percent_Identity=28.2312925170068, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786753, Length=294, Percent_Identity=28.2312925170068, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786570, Length=294, Percent_Identity=28.2312925170068, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786490, Length=294, Percent_Identity=28.2312925170068, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337
- InterPro:   IPR002514 [H]

Pfam domain/function: PF00665 rve; PF01527 Transposase_8 [H]

EC number: NA

Molecular weight: Translated: 58995; Mature: 58995

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSYEDRIRAVRLYIKLGKRTGATIRQLGYPTKNALKSWHREYEQGGNLRVGHVRSRSKY
CCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHH
SAEQKRVAVEHYLNHDRFLAGTRKALGYPCRDTLAAWVHELLPETRRKVVGKAQAVLLPR
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEECCH
EAKQAAVIELCTRQVSAQAIAQKLGVTRPTLYKWKNQLLGREAPASMKRSNDSGSTPKPK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCH
ELTELQQQVELLERDIRRLQLEHDLLKKANELLKKGLGVDMQLLTNREKTLLVDALKELY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHH
ALPELLAQLDLARSSYFYHRARVKMADKYLAVRQTLTDIFELNHRCYGYRRLQASLTRQC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTISEKVVQRLMKQESLVVAKPKRRRYGSYLGEISPAPENLINRDFHAAAPNEKWLTDIT
HHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHH
EFQIPAGKVYLSPIIDCFDGLVISWTIGTHPDAELVNTMLDAAIETVAGGNDRPVVHSDR
HHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCC
GAHYRWPGWLSRIGDAKLIRSMSRKGCSPDNAACEGFFGRLKTELFYPRDWKTTTIEQFI
CCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QVVDSYIRWYNEKRIKISLGSLSPIEYRESLGLTA
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCC
>Mature Secondary Structure
MYSYEDRIRAVRLYIKLGKRTGATIRQLGYPTKNALKSWHREYEQGGNLRVGHVRSRSKY
CCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHH
SAEQKRVAVEHYLNHDRFLAGTRKALGYPCRDTLAAWVHELLPETRRKVVGKAQAVLLPR
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEECCH
EAKQAAVIELCTRQVSAQAIAQKLGVTRPTLYKWKNQLLGREAPASMKRSNDSGSTPKPK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCH
ELTELQQQVELLERDIRRLQLEHDLLKKANELLKKGLGVDMQLLTNREKTLLVDALKELY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHH
ALPELLAQLDLARSSYFYHRARVKMADKYLAVRQTLTDIFELNHRCYGYRRLQASLTRQC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTISEKVVQRLMKQESLVVAKPKRRRYGSYLGEISPAPENLINRDFHAAAPNEKWLTDIT
HHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHH
EFQIPAGKVYLSPIIDCFDGLVISWTIGTHPDAELVNTMLDAAIETVAGGNDRPVVHSDR
HHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCC
GAHYRWPGWLSRIGDAKLIRSMSRKGCSPDNAACEGFFGRLKTELFYPRDWKTTTIEQFI
CCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QVVDSYIRWYNEKRIKISLGSLSPIEYRESLGLTA
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755869; 12499211 [H]