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The map label for this gene is tdcB [H]

Identifier: 91786076

GI number: 91786076

Start: 177751

End: 178953

Strand: Reverse

Name: tdcB [H]

Synonym: Bpro_0165

Alternate gene names: 91786076

Gene position: 178953-177751 (Counterclockwise)

Preceding gene: 91786078

Following gene: 91786071

Centisome position: 3.44

GC content: 66.58

Gene sequence:

>1203_bases
ATGCTCAGTCTGACCGATATTGAACAAGCCGCCCAGCGCCTGCAGGGCCATTTGCTGGATACCCCCTGCGTGGAGTCCAG
GACGCTGTCACAGCTGACCGGGGCGCAGATTTACCTGAAATTTGAAAACCTGCAGTACACGGCCTCTTTCAAGGAGCGTG
GCGCCTGCAACAAACTTGCGCAACTCTCAGGCGACGAACGGCGCCGCGGCGTGATCGCGATGAGCGCCGGCAACCATGCC
CAGGGTGTGGCTTATCATGCCCAGCGCCTGGGCCTGAGGGCCGTCATCGTGATGCCGCGCTTCACGCCCGGCGTCAAGAC
CGAGCGTACCCGCGGCTTTGGCGCGGAGGTGGTGCTGCACGGCGACACGCTGGAGGAGTCGCGCGCCCACGCGCTGATGC
TGGCCGAGCGCGAGGGCCTGGTGTTTGTGCACCCCTACGACGACGAAGCTATCGTGGCGGGCCAGGGCACCGTGGGGCTG
GAAATGCTGCACGCCGTCCCCGGCCTGGACACGCTGGTCGTCGCCGTGGGCGGCGGCGGGCTGATCGCGGGCATGGCCAT
CGCCGCCAAGGCCCTGAAGCCCGAGATTGAAATCGTGGGGGTGCAGACCTCGCGCTTTCCGGCCATGGTCAACGCCATCA
AGGGCACGCACCACCCGCAGGGCACCAGCACCATTGCCGAGGGCATCGCCGTGGGCACGCCGGGGGTCATCCCGCAAGCC
ATCATTGAAAAGCTGGTGGACGACCTGGTGCTGGTCGATGAAGGGGATATCGAGCAGGCCATGGTGATGCTGCTGGAAAT
TGAAAAAACCCTGGTCGAGGGTGCGGGCGCGGCCGGCTTGGCGGCGGTGCTCAAATACCCGGCGCGCTTTGCCGGCAAGA
AAGTCGGGCTGGTGCTGTGCGGCGGCAATATCGACCCGCTGCTGCTGGCGGCCATCATCGAGCGCGGCATGGTGCGCGCC
GGGCGGCTGGCCCGCATCAAGGTCAGCGTGCGTGACGTGCCAGGCTCGCTGGCCAAGATCACCGCGACGGTAGCCGATGC
GGGCGCCAACATCGACGAGGTACACCACCAGCGCGCCTTCACCACGCTGTCGGTCCAGAATGTGGAGATCGAGCTGGTGA
TCCAGACGCGCGGGCGCGAGCACATCGCGCAGGTGCTGGCGGCGCTGGCCGCAGCCGGATTTGAGGCGTCCGAGCAGCAC
TGA

Upstream 100 bases:

>100_bases
ATCATGGAAGACGCTACTTGAAGGCCCTCGTGTGAAATGTGCCACACAAGCGGCTGAAAATGGCATGTTCAGGGCACACA
ATCTGCCGAGGAGAACCTTC

Downstream 100 bases:

>100_bases
ACGTCCGCCGCCCCCTATGGCTTTCATCGTCCCGTTGCGGCTGGCGGGAGGGGACTCGCCGGACTAGGGCCTGTGAACGC
TATTTATGCAAGATGCGTTG

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MLSLTDIEQAAQRLQGHLLDTPCVESRTLSQLTGAQIYLKFENLQYTASFKERGACNKLAQLSGDERRRGVIAMSAGNHA
QGVAYHAQRLGLRAVIVMPRFTPGVKTERTRGFGAEVVLHGDTLEESRAHALMLAEREGLVFVHPYDDEAIVAGQGTVGL
EMLHAVPGLDTLVVAVGGGGLIAGMAIAAKALKPEIEIVGVQTSRFPAMVNAIKGTHHPQGTSTIAEGIAVGTPGVIPQA
IIEKLVDDLVLVDEGDIEQAMVMLLEIEKTLVEGAGAAGLAAVLKYPARFAGKKVGLVLCGGNIDPLLLAAIIERGMVRA
GRLARIKVSVRDVPGSLAKITATVADAGANIDEVHHQRAFTTLSVQNVEIELVIQTRGREHIAQVLAALAAAGFEASEQH

Sequences:

>Translated_400_residues
MLSLTDIEQAAQRLQGHLLDTPCVESRTLSQLTGAQIYLKFENLQYTASFKERGACNKLAQLSGDERRRGVIAMSAGNHA
QGVAYHAQRLGLRAVIVMPRFTPGVKTERTRGFGAEVVLHGDTLEESRAHALMLAEREGLVFVHPYDDEAIVAGQGTVGL
EMLHAVPGLDTLVVAVGGGGLIAGMAIAAKALKPEIEIVGVQTSRFPAMVNAIKGTHHPQGTSTIAEGIAVGTPGVIPQA
IIEKLVDDLVLVDEGDIEQAMVMLLEIEKTLVEGAGAAGLAAVLKYPARFAGKKVGLVLCGGNIDPLLLAAIIERGMVRA
GRLARIKVSVRDVPGSLAKITATVADAGANIDEVHHQRAFTTLSVQNVEIELVIQTRGREHIAQVLAALAAAGFEASEQH
>Mature_400_residues
MLSLTDIEQAAQRLQGHLLDTPCVESRTLSQLTGAQIYLKFENLQYTASFKERGACNKLAQLSGDERRRGVIAMSAGNHA
QGVAYHAQRLGLRAVIVMPRFTPGVKTERTRGFGAEVVLHGDTLEESRAHALMLAEREGLVFVHPYDDEAIVAGQGTVGL
EMLHAVPGLDTLVVAVGGGGLIAGMAIAAKALKPEIEIVGVQTSRFPAMVNAIKGTHHPQGTSTIAEGIAVGTPGVIPQA
IIEKLVDDLVLVDEGDIEQAMVMLLEIEKTLVEGAGAAGLAAVLKYPARFAGKKVGLVLCGGNIDPLLLAAIIERGMVRA
GRLARIKVSVRDVPGSLAKITATVADAGANIDEVHHQRAFTTLSVQNVEIELVIQTRGREHIAQVLAALAAAGFEASEQH

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=315, Percent_Identity=37.4603174603175, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI19923959, Length=145, Percent_Identity=37.2413793103448, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI33469958, Length=281, Percent_Identity=31.3167259786477, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789505, Length=310, Percent_Identity=40.9677419354839, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1790207, Length=379, Percent_Identity=34.8284960422164, Blast_Score=173, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71991565, Length=392, Percent_Identity=42.3469387755102, Blast_Score=278, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17537387, Length=388, Percent_Identity=38.659793814433, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17508781, Length=310, Percent_Identity=31.2903225806452, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6322631, Length=317, Percent_Identity=37.8548895899054, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6320930, Length=401, Percent_Identity=33.4164588528678, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6319788, Length=191, Percent_Identity=30.3664921465969, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355833, Length=387, Percent_Identity=39.5348837209302, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24645328, Length=291, Percent_Identity=37.8006872852234, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 42253; Mature: 42253

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLTDIEQAAQRLQGHLLDTPCVESRTLSQLTGAQIYLKFENLQYTASFKERGACNKLA
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEEEEECEEEEECHHHCCCHHHHH
QLSGDERRRGVIAMSAGNHAQGVAYHAQRLGLRAVIVMPRFTPGVKTERTRGFGAEVVLH
HCCCCCHHCCEEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEE
GDTLEESRAHALMLAEREGLVFVHPYDDEAIVAGQGTVGLEMLHAVPGLDTLVVAVGGGG
CCCCCCCCCEEEEEEECCCEEEEECCCCCEEEECCCCHHHHHHHHCCCCCEEEEEECCCH
LIAGMAIAAKALKPEIEIVGVQTSRFPAMVNAIKGTHHPQGTSTIAEGIAVGTPGVIPQA
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHH
IIEKLVDDLVLVDEGDIEQAMVMLLEIEKTLVEGAGAAGLAAVLKYPARFAGKKVGLVLC
HHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEE
GGNIDPLLLAAIIERGMVRAGRLARIKVSVRDVPGSLAKITATVADAGANIDEVHHQRAF
CCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHEEHHHHCCCCHHHHHHHHHE
TTLSVQNVEIELVIQTRGREHIAQVLAALAAAGFEASEQH
EEEEEECEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLSLTDIEQAAQRLQGHLLDTPCVESRTLSQLTGAQIYLKFENLQYTASFKERGACNKLA
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEEEEECEEEEECHHHCCCHHHHH
QLSGDERRRGVIAMSAGNHAQGVAYHAQRLGLRAVIVMPRFTPGVKTERTRGFGAEVVLH
HCCCCCHHCCEEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEE
GDTLEESRAHALMLAEREGLVFVHPYDDEAIVAGQGTVGLEMLHAVPGLDTLVVAVGGGG
CCCCCCCCCEEEEEEECCCEEEEECCCCCEEEECCCCHHHHHHHHCCCCCEEEEEECCCH
LIAGMAIAAKALKPEIEIVGVQTSRFPAMVNAIKGTHHPQGTSTIAEGIAVGTPGVIPQA
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHH
IIEKLVDDLVLVDEGDIEQAMVMLLEIEKTLVEGAGAAGLAAVLKYPARFAGKKVGLVLC
HHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEE
GGNIDPLLLAAIIERGMVRAGRLARIKVSVRDVPGSLAKITATVADAGANIDEVHHQRAF
CCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHEEHHHHCCCCHHHHHHHHHE
TTLSVQNVEIELVIQTRGREHIAQVLAALAAAGFEASEQH
EEEEEECEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA