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The map label for this gene is yciC [H]

Identifier: 91785775

GI number: 91785775

Start: 4850612

End: 4851928

Strand: Reverse

Name: yciC [H]

Synonym: Bxe_A4503

Alternate gene names: 91785775

Gene position: 4851928-4850612 (Counterclockwise)

Preceding gene: 91785776

Following gene: 91785773

Centisome position: 99.1

GC content: 64.77

Gene sequence:

>1317_bases
ATGAACCAGCCGCTATTGCCCGTCACCGTGCTCTCCGGTTTTCTGGGCGCCGGCAAGACCACGCTCCTGAATCACATTCT
CGCGAATCGCGCCGGTTTGCGCGTGGCCGTGATCGTCAACGATCTGGCCGCCGTCAATATCGACGCAACGCTCGTGCGCG
ACGCAGCCGCGCTTTCTCACATCGAGGAGCAACTCGTCGAGTTGTCGAACGGCTGCATCTGCTGCACGTTGCGTGACGAT
TTGCGGGTCGAGATCAAGCGTCTCGCGGCCCAGCAGCGCTTCGACGCGATCCTGATCGAGTCGACCGGCGTGGCCGAACC
CATGCCGATCGCCGAAACCTTCACCTTCGTCGACGACGAAGGTGCGTCGCTGTCCGACGTCGCGCGACTCGATACGATGG
TGACCGTGGTCGATGCATTCAACTTCCTGCGCGACTATGGTTCGGCCGACGCGCTCGCCGAGCGCGGCATCGCGGCGAGC
GAAGAAGACGACCGCACGCTCGTGGAGTTGCTGATCGAACAGATCGAGTTCTGCGACGTGCTGGTGGTGAACAAGGCCGA
CCTGGTCGGCGCAGATGAACTCACGCGCCTGCAGCGCATTCTCGGCCGGATCAACCCGCGCGCCGTGCAGGTGGTCGCCC
GTTTCGGCGAGGTGCCGCTCGCGCAGGTGCTGAACACCGGCCGCTTCGATTTCGACGAGGCATCGAGCGCGCCGGGCTGG
CTGGCGTCGCTCAATCATGAGCACGGCCACGAGCACGGTCACGCCCATCACGGCGAGGCGGACGAATTCGGCATCGGCAA
TTTCATTTACCGGGCGCGCCGGCCGTTTCACCCGGAACGCCTGTGGGCGCTGCTGCATCAGGAGTGGAAGGGCGTTCTGC
GCAGCAAAGGCTTCTTCTGGCTGGCCACGCGTAACGATATCGCCGGTTCGCTCTCGCAGGCGGGCGGGGCTTGCCGGCAC
GGCCCGGCGGGCATGTGGTGGGCCGCTCAGGATCGCAGCGAATGGCCCGACGGCGACGACGAGCTGGCCGCCGAAATCGC
CGCGGACTGGTACGGCGACCCGGACGATCTGAGCATTGGCGACCGTCGCCAGGAACTGGTCATGATCGGTATCGGCATCG
ACCCGGCCGTGTGGACCGCGAAGTTCGACGCCTGCCTGTTGACCGATGAGGAATACGCACAGGGACCGCAAGCATGGGCG
AAGTTCGCCGATCCGTTCCCGGCCTGGGACTTCGACGAAGATGATCACGACCACGACCATCATGACCATGATCACGATGG
TCACGGCCACGGCGAGATCGTGCATCGCCACGACTGA

Upstream 100 bases:

>100_bases
GCTTCGTGCTGCCGTCGCGCCCCGAACATCATTCGGGTCACGCAGTCATGCGGCCCCAAGCCCGGCACGCCTTCCAATCC
ACTAGCTTTTCCGTACTGCG

Downstream 100 bases:

>100_bases
ACGGCCTTTGCCTGCCGCCGGGATAGCCGCGACGCTCGCCGCCGCTATCCCTTGCCCACTGCGCAGCGCGAACGCGCAGG
CCAAAAAAAACCCGCCGTTG

Product: putative cobalamin synthesis protein/P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNQPLLPVTVLSGFLGAGKTTLLNHILANRAGLRVAVIVNDLAAVNIDATLVRDAAALSHIEEQLVELSNGCICCTLRDD
LRVEIKRLAAQQRFDAILIESTGVAEPMPIAETFTFVDDEGASLSDVARLDTMVTVVDAFNFLRDYGSADALAERGIAAS
EEDDRTLVELLIEQIEFCDVLVVNKADLVGADELTRLQRILGRINPRAVQVVARFGEVPLAQVLNTGRFDFDEASSAPGW
LASLNHEHGHEHGHAHHGEADEFGIGNFIYRARRPFHPERLWALLHQEWKGVLRSKGFFWLATRNDIAGSLSQAGGACRH
GPAGMWWAAQDRSEWPDGDDELAAEIAADWYGDPDDLSIGDRRQELVMIGIGIDPAVWTAKFDACLLTDEEYAQGPQAWA
KFADPFPAWDFDEDDHDHDHHDHDHDGHGHGEIVHRHD

Sequences:

>Translated_438_residues
MNQPLLPVTVLSGFLGAGKTTLLNHILANRAGLRVAVIVNDLAAVNIDATLVRDAAALSHIEEQLVELSNGCICCTLRDD
LRVEIKRLAAQQRFDAILIESTGVAEPMPIAETFTFVDDEGASLSDVARLDTMVTVVDAFNFLRDYGSADALAERGIAAS
EEDDRTLVELLIEQIEFCDVLVVNKADLVGADELTRLQRILGRINPRAVQVVARFGEVPLAQVLNTGRFDFDEASSAPGW
LASLNHEHGHEHGHAHHGEADEFGIGNFIYRARRPFHPERLWALLHQEWKGVLRSKGFFWLATRNDIAGSLSQAGGACRH
GPAGMWWAAQDRSEWPDGDDELAAEIAADWYGDPDDLSIGDRRQELVMIGIGIDPAVWTAKFDACLLTDEEYAQGPQAWA
KFADPFPAWDFDEDDHDHDHHDHDHDGHGHGEIVHRHD
>Mature_438_residues
MNQPLLPVTVLSGFLGAGKTTLLNHILANRAGLRVAVIVNDLAAVNIDATLVRDAAALSHIEEQLVELSNGCICCTLRDD
LRVEIKRLAAQQRFDAILIESTGVAEPMPIAETFTFVDDEGASLSDVARLDTMVTVVDAFNFLRDYGSADALAERGIAAS
EEDDRTLVELLIEQIEFCDVLVVNKADLVGADELTRLQRILGRINPRAVQVVARFGEVPLAQVLNTGRFDFDEASSAPGW
LASLNHEHGHEHGHAHHGEADEFGIGNFIYRARRPFHPERLWALLHQEWKGVLRSKGFFWLATRNDIAGSLSQAGGACRH
GPAGMWWAAQDRSEWPDGDDELAAEIAADWYGDPDDLSIGDRRQELVMIGIGIDPAVWTAKFDACLLTDEEYAQGPQAWA
KFADPFPAWDFDEDDHDHDHHDHDHDGHGHGEIVHRHD

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI146231952, Length=229, Percent_Identity=33.1877729257642, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI148727351, Length=229, Percent_Identity=32.7510917030568, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI33469141, Length=229, Percent_Identity=32.7510917030568, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI126722884, Length=229, Percent_Identity=32.7510917030568, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI223941779, Length=204, Percent_Identity=33.8235294117647, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI223941776, Length=219, Percent_Identity=32.4200913242009, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI119120938, Length=143, Percent_Identity=38.4615384615385, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87082430, Length=242, Percent_Identity=32.6446280991736, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788499, Length=193, Percent_Identity=29.0155440414508, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324356, Length=234, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 48393; Mature: 48393

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPLLPVTVLSGFLGAGKTTLLNHILANRAGLRVAVIVNDLAAVNIDATLVRDAAALSH
CCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECHHHCCCCHHHHHHHHHHHH
IEEQLVELSNGCICCTLRDDLRVEIKRLAAQQRFDAILIESTGVAEPMPIAETFTFVDDE
HHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCHHHHEEEECCC
GASLSDVARLDTMVTVVDAFNFLRDYGSADALAERGIAASEEDDRTLVELLIEQIEFCDV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCE
LVVNKADLVGADELTRLQRILGRINPRAVQVVARFGEVPLAQVLNTGRFDFDEASSAPGW
EEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCH
LASLNHEHGHEHGHAHHGEADEFGIGNFIYRARRPFHPERLWALLHQEWKGVLRSKGFFW
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEE
LATRNDIAGSLSQAGGACRHGPAGMWWAAQDRSEWPDGDDELAAEIAADWYGDPDDLSIG
EEECCCHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
DRRQELVMIGIGIDPAVWTAKFDACLLTDEEYAQGPQAWAKFADPFPAWDFDEDDHDHDH
CCCCEEEEEEECCCCHHHHEECCEEEECCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCC
HDHDHDGHGHGEIVHRHD
CCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MNQPLLPVTVLSGFLGAGKTTLLNHILANRAGLRVAVIVNDLAAVNIDATLVRDAAALSH
CCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECHHHCCCCHHHHHHHHHHHH
IEEQLVELSNGCICCTLRDDLRVEIKRLAAQQRFDAILIESTGVAEPMPIAETFTFVDDE
HHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCHHHHEEEECCC
GASLSDVARLDTMVTVVDAFNFLRDYGSADALAERGIAASEEDDRTLVELLIEQIEFCDV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCE
LVVNKADLVGADELTRLQRILGRINPRAVQVVARFGEVPLAQVLNTGRFDFDEASSAPGW
EEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCH
LASLNHEHGHEHGHAHHGEADEFGIGNFIYRARRPFHPERLWALLHQEWKGVLRSKGFFW
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEE
LATRNDIAGSLSQAGGACRHGPAGMWWAAQDRSEWPDGDDELAAEIAADWYGDPDDLSIG
EEECCCHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
DRRQELVMIGIGIDPAVWTAKFDACLLTDEEYAQGPQAWAKFADPFPAWDFDEDDHDHDH
CCCCEEEEEEECCCCHHHHEECCEEEECCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCC
HDHDHDGHGHGEIVHRHD
CCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]