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The map label for this gene is glmS [H]

Identifier: 91785569

GI number: 91785569

Start: 4624493

End: 4626310

Strand: Reverse

Name: glmS [H]

Synonym: Bxe_A0208

Alternate gene names: 91785569

Gene position: 4626310-4624493 (Counterclockwise)

Preceding gene: 91785570

Following gene: 91785568

Centisome position: 94.49

GC content: 63.2

Gene sequence:

>1818_bases
ATGTGTGGCATTGTCGGCGCGGTAGCGCAACGTAATATCGTCCCCGTCCTGATCGAAGGACTGCGTCGCCTCGAGTATCG
CGGCTACGATTCGTGCGGCGTGGCCGTGCTCGGCAGCGACGGTCCGCGCCGTGCGCGCAGCGTCGCGCGTGTGGCCGATC
TCGACGAGCAGGTGCGCGAGAGCCATCTTGAAGGCATCACGGGTATCGCGCATACGCGCTGGGCCACGCACGGCGCGCCG
GTCACGGACAACGCCCACCCGATCTTCTCGAAAGACGCACTCGCGTTGGTACACAACGGCATCATCGAGAACTACGAGAC
GCTGCGCGACATGCTGCGCGGCAAGGGTTACACGTTTGTTTCGCAGACCGACACAGAGGTTATCGCGCATCTGATTCACA
GCCTGTATCACGGCGATCTGTTCGCGGCGGTGCGCGAAGCGGTCGGGCAACTGCACGGCGCGTATGCGATCGCCGTGTTG
CATAAAGACCAGCCGCATACGGTGGTCGGCGCGCGGCAGGGTTCGCCGCTGGTGGTCGGGCTCGGCGAGGGCGAGAACTT
CCTTGCCTCGGACGCGTTGGCGCTCGCGGGCAGCACCGAACGGTTCATCTTCCTCGAAGAAGGCGACGTCTGCGAACTGA
CGCTCGAGGGCGTGCGCATCGCCGATCGCGACGGCTACGAGGCGCAGCGCGAAGTGCGCCAGGTGGCGGCGTATGGCGGC
GCGGTCGAACTCGGCCCGTATCGTCACTTCATGCAGAAGGAAATCTTCGAACAGCCGCGCGCGATCACGGACACGATTCC
GCAAGCGGATTCGTTCGACCCGTCGTTATTCGGCGAGGGCGCGGGCAAGGTGTTCGCGGAGATCGACAGCCTGCTGATTC
TGGCGTGCGGCACGAGCTATTACTCGGGGCTGACCGCGAAATACTGGCTCGAATCGATCGCGAAGATTCCCACGCAGGTG
GAAATTGCCAGCGAGTATCGTTACCGCGAGTCGGTGCCGAATCCGAAGTCGCTGGTCGTCGTGATCTCCCAATCGGGCGA
AACGGCGGACACGCTGGCGGCGCTCAAGCATGCACAGGAGCTCGGTCACAAGCATACGCTGGCAATCTGCAACGTCGGTA
CGAGCGCGATGGTGCGCCAGACCGAGCTGGCGTTCCTGACGCACGCGGGCCGCGAGATCGGTGTGGCATCGACCAAGGCG
TTCACGACGCAGCTGGTTGGGCTGTTCGTGTTGGCGGCAACGCTGGGCAAGTTGCGCGGGCGTGTGAGCGAAGAGCAGGA
AGGGGAGTATCTGAAGCAACTGCGTCACTTGCCGGCGGCATTGAATAGCGTGCTGGCGCTGGAGCCGCAGATCATTGCGT
GGTCGGAAGAGTTTTCGCGCAAGGAGCATGCGCTGTTTCTCGGGCGCGGCTTGCATTATCCGATCGCACTCGAGGGCGCG
CTCAAGCTCAAGGAGATCTCGTATATCCACGCCGAGGCTTATCCGGCCGGCGAGTTGAAGCATGGGCCGCTCGCGCTCGT
GACCGAAGCCATGCCGGTGGTGACGGTGGCGCCGAACGACGCGCTGCTGGAAAAGCTGAAGTCGAATATTCAGGAAGTGC
GCGCGCGCGGCGGTCAGCTGTATGTGTTCGCCGACGCGGATACGAAGATCGTCAACGACGAAGGTTTGCATGTGATCCGG
ATGCCGGAGCATTACGGCCTGTTGTCGCCGATCTTGCATGTGGTGCCGCTGCAGTTGCTGGCGTATCACACGGCGTGTGC
GCGCGGTACGGATGTGGATAAGCCGCGGAATCTGGCGAAGTCTGTGACGGTGGAGTGA

Upstream 100 bases:

>100_bases
GGCTACGTGCGCCCGACCAAAAAGAAGAGCTGATGGGTACGACGCGCGCCCGAGGCGCGCTCCTTGAAACCCGGCACTAG
CACTGAAAAAGGAATGATCC

Downstream 100 bases:

>100_bases
GGGGGGCTTAACGCCACCATGCTGTCCCGCCCAAATAGAAAGCTTCCGGAAGTAGTGGTCGGAAGCTTTTTGCGAGGGGG
GCTCAACCCCTCGCTCAGCC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGSDGPRRARSVARVADLDEQVRESHLEGITGIAHTRWATHGAP
VTDNAHPIFSKDALALVHNGIIENYETLRDMLRGKGYTFVSQTDTEVIAHLIHSLYHGDLFAAVREAVGQLHGAYAIAVL
HKDQPHTVVGARQGSPLVVGLGEGENFLASDALALAGSTERFIFLEEGDVCELTLEGVRIADRDGYEAQREVRQVAAYGG
AVELGPYRHFMQKEIFEQPRAITDTIPQADSFDPSLFGEGAGKVFAEIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPKSLVVVISQSGETADTLAALKHAQELGHKHTLAICNVGTSAMVRQTELAFLTHAGREIGVASTKA
FTTQLVGLFVLAATLGKLRGRVSEEQEGEYLKQLRHLPAALNSVLALEPQIIAWSEEFSRKEHALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDALLEKLKSNIQEVRARGGQLYVFADADTKIVNDEGLHVIR
MPEHYGLLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Sequences:

>Translated_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGSDGPRRARSVARVADLDEQVRESHLEGITGIAHTRWATHGAP
VTDNAHPIFSKDALALVHNGIIENYETLRDMLRGKGYTFVSQTDTEVIAHLIHSLYHGDLFAAVREAVGQLHGAYAIAVL
HKDQPHTVVGARQGSPLVVGLGEGENFLASDALALAGSTERFIFLEEGDVCELTLEGVRIADRDGYEAQREVRQVAAYGG
AVELGPYRHFMQKEIFEQPRAITDTIPQADSFDPSLFGEGAGKVFAEIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPKSLVVVISQSGETADTLAALKHAQELGHKHTLAICNVGTSAMVRQTELAFLTHAGREIGVASTKA
FTTQLVGLFVLAATLGKLRGRVSEEQEGEYLKQLRHLPAALNSVLALEPQIIAWSEEFSRKEHALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDALLEKLKSNIQEVRARGGQLYVFADADTKIVNDEGLHVIR
MPEHYGLLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE
>Mature_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGSDGPRRARSVARVADLDEQVRESHLEGITGIAHTRWATHGAP
VTDNAHPIFSKDALALVHNGIIENYETLRDMLRGKGYTFVSQTDTEVIAHLIHSLYHGDLFAAVREAVGQLHGAYAIAVL
HKDQPHTVVGARQGSPLVVGLGEGENFLASDALALAGSTERFIFLEEGDVCELTLEGVRIADRDGYEAQREVRQVAAYGG
AVELGPYRHFMQKEIFEQPRAITDTIPQADSFDPSLFGEGAGKVFAEIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPKSLVVVISQSGETADTLAALKHAQELGHKHTLAICNVGTSAMVRQTELAFLTHAGREIGVASTKA
FTTQLVGLFVLAATLGKLRGRVSEEQEGEYLKQLRHLPAALNSVLALEPQIIAWSEEFSRKEHALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDALLEKLKSNIQEVRARGGQLYVFADADTKIVNDEGLHVIR
MPEHYGLLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=685, Percent_Identity=37.0802919708029, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI4826742, Length=687, Percent_Identity=35.6622998544396, Blast_Score=384, Evalue=1e-106,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=56.4648117839607, Blast_Score=663, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=241, Percent_Identity=28.2157676348548, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17539970, Length=434, Percent_Identity=39.1705069124424, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17532899, Length=433, Percent_Identity=38.1062355658199, Blast_Score=275, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI17532897, Length=433, Percent_Identity=38.1062355658199, Blast_Score=275, Evalue=7e-74,
Organism=Saccharomyces cerevisiae, GI6322745, Length=448, Percent_Identity=36.8303571428571, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6323731, Length=433, Percent_Identity=30.2540415704388, Blast_Score=197, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=34.6341463414634, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323958, Length=176, Percent_Identity=29.5454545454545, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357745, Length=685, Percent_Identity=35.3284671532847, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI28573187, Length=255, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24659598, Length=258, Percent_Identity=27.1317829457364, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65825; Mature: 65825

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGSDGPRRARSVARVADLDEQVRE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
SHLEGITGIAHTRWATHGAPVTDNAHPIFSKDALALVHNGIIENYETLRDMLRGKGYTFV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
SQTDTEVIAHLIHSLYHGDLFAAVREAVGQLHGAYAIAVLHKDQPHTVVGARQGSPLVVG
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCEEEE
LGEGENFLASDALALAGSTERFIFLEEGDVCELTLEGVRIADRDGYEAQREVRQVAAYGG
CCCCCCHHHHHHHHCCCCCCEEEEEECCCEEEEEECCEEEECCCCCHHHHHHHHHHHCCC
AVELGPYRHFMQKEIFEQPRAITDTIPQADSFDPSLFGEGAGKVFAEIDSLLILACGTSY
CEEECHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHEEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPKSLVVVISQSGETADTLAALKHAQE
HCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHKHTLAICNVGTSAMVRQTELAFLTHAGREIGVASTKAFTTQLVGLFVLAATLGKLRG
CCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
RVSEEQEGEYLKQLRHLPAALNSVLALEPQIIAWSEEFSRKEHALFLGRGLHYPIALEGA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCHHHEEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDALLEKLKSNIQEVRARGGQL
EEHHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTKIVNDEGLHVIRMPEHYGLLSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC
>Mature Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLGSDGPRRARSVARVADLDEQVRE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
SHLEGITGIAHTRWATHGAPVTDNAHPIFSKDALALVHNGIIENYETLRDMLRGKGYTFV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
SQTDTEVIAHLIHSLYHGDLFAAVREAVGQLHGAYAIAVLHKDQPHTVVGARQGSPLVVG
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCEEEE
LGEGENFLASDALALAGSTERFIFLEEGDVCELTLEGVRIADRDGYEAQREVRQVAAYGG
CCCCCCHHHHHHHHCCCCCCEEEEEECCCEEEEEECCEEEECCCCCHHHHHHHHHHHCCC
AVELGPYRHFMQKEIFEQPRAITDTIPQADSFDPSLFGEGAGKVFAEIDSLLILACGTSY
CEEECHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHEEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPKSLVVVISQSGETADTLAALKHAQE
HCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHKHTLAICNVGTSAMVRQTELAFLTHAGREIGVASTKAFTTQLVGLFVLAATLGKLRG
CCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
RVSEEQEGEYLKQLRHLPAALNSVLALEPQIIAWSEEFSRKEHALFLGRGLHYPIALEGA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCHHHEEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDALLEKLKSNIQEVRARGGQL
EEHHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTKIVNDEGLHVIRMPEHYGLLSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]