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The map label for this gene is ywlC [H]

Identifier: 91785085

GI number: 91785085

Start: 4116589

End: 4117629

Strand: Reverse

Name: ywlC [H]

Synonym: Bxe_A0695

Alternate gene names: 91785085

Gene position: 4117629-4116589 (Counterclockwise)

Preceding gene: 91785086

Following gene: 91785081

Centisome position: 84.1

GC content: 65.13

Gene sequence:

>1041_bases
ATGCCGGATCAACAGAAAGCCGCCGAAGGCGCATTGCCTGTGAGCGCCGCGCAGATCGAACACGCGGCGGCGCTGCTGGA
CGCGGGAGAGCTGGTCGCGTTCCCCACGGAGACGGTGTACGGTCTCGGCGGCGACGCGGAGAATCCTGACGCGGTCGCGC
GTATTTATGCGGCGAAGGGCCGGCCGGCGAATCATCCCGTCATCGTGCATCTCGCGCCGCAAGGCGATCCGAACTACTGG
GTCGAGCATTTGCCGGCGGATGCTCAGCGGCTGATCGACGCGTTCTGGCCTGGCCCGCTCACGTTGATCCTGAAGCGCGC
CGCCCGCATTCCGGCGGCGGTGAGCGGCGGGCAGGATTCGGTGGGGCTGCGCTGCCCGTCGCATCCTGTCGCGCAAGCTT
TGCTTGAGGCGTTCAGCGCATTGCGCAGCGGACATGGCGGTGTGGCGGCGCCGTCGGCGAACCGGTTCGGCCATGTGAGC
CCGACCACGGCGCAACATGTGCGGGACGAGTTCGGCGACACGATTCATGTGCTGGACGGCGGCGCTTCGGATGTGGGTAT
CGAATCGACCATTCTGGATTTGTCGCGCGGCTTTCCGGCGCTGTTGAGGCCGGGGCGTGTCACGCCGCAGGATATCGCCG
ACGTGCTCGGCGAGGCGCCGCGCTTGCCCGATGGTTCGGACGCGACTGCGCCGCGCGCTTCCGGCACGTTGAAGGCGCAC
TATGCGCCGAGCACGCCTTTGGCGTTATTGCCTTTTGGTGCGCTGGAGACTTTGCTTGCCGCGCGGCATGTGGACGAACG
CGTGGCGTTGGTGGCGCGGGTTTCCCGTGCTGGGCATTGGGCCGATGCAGAAGGGGTGCATTTCGTTGCTGCGCCTGAAG
ATCCGCATGTCTATGCGCGTGAACTGTATGGGTTGTTGAGGGCGCTTGATCGCGCGAACGTCACGCGAATTCTTATCGAG
AAGTTGCCGGATACGATTGAGTGGATTGCTGTTAATGATCGGTTGGGGCGGGCTGCGGCTGCTTTTGAAGCGCAGGGGTG
A

Upstream 100 bases:

>100_bases
GGCCACGTGAACTTCACGGCGGCTACGCTCGAAGAAGCCCGCACCGCTGCGCGCGATTGCGCACGGCTTCTGCACATCAT
CACGAGCTGACACGAGAGCC

Downstream 100 bases:

>100_bases
TGGGTGGGGGTTTTGCCTGTGCGGCGGGTTTTGTTTGGTTGTTTTGGGCTTTTCTTGAATCGTTTCTGGTTTATTAGCGT
TGCCCCTGTGCGGGGCGGCA

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MPDQQKAAEGALPVSAAQIEHAAALLDAGELVAFPTETVYGLGGDAENPDAVARIYAAKGRPANHPVIVHLAPQGDPNYW
VEHLPADAQRLIDAFWPGPLTLILKRAARIPAAVSGGQDSVGLRCPSHPVAQALLEAFSALRSGHGGVAAPSANRFGHVS
PTTAQHVRDEFGDTIHVLDGGASDVGIESTILDLSRGFPALLRPGRVTPQDIADVLGEAPRLPDGSDATAPRASGTLKAH
YAPSTPLALLPFGALETLLAARHVDERVALVARVSRAGHWADAEGVHFVAAPEDPHVYARELYGLLRALDRANVTRILIE
KLPDTIEWIAVNDRLGRAAAAFEAQG

Sequences:

>Translated_346_residues
MPDQQKAAEGALPVSAAQIEHAAALLDAGELVAFPTETVYGLGGDAENPDAVARIYAAKGRPANHPVIVHLAPQGDPNYW
VEHLPADAQRLIDAFWPGPLTLILKRAARIPAAVSGGQDSVGLRCPSHPVAQALLEAFSALRSGHGGVAAPSANRFGHVS
PTTAQHVRDEFGDTIHVLDGGASDVGIESTILDLSRGFPALLRPGRVTPQDIADVLGEAPRLPDGSDATAPRASGTLKAH
YAPSTPLALLPFGALETLLAARHVDERVALVARVSRAGHWADAEGVHFVAAPEDPHVYARELYGLLRALDRANVTRILIE
KLPDTIEWIAVNDRLGRAAAAFEAQG
>Mature_345_residues
PDQQKAAEGALPVSAAQIEHAAALLDAGELVAFPTETVYGLGGDAENPDAVARIYAAKGRPANHPVIVHLAPQGDPNYWV
EHLPADAQRLIDAFWPGPLTLILKRAARIPAAVSGGQDSVGLRCPSHPVAQALLEAFSALRSGHGGVAAPSANRFGHVSP
TTAQHVRDEFGDTIHVLDGGASDVGIESTILDLSRGFPALLRPGRVTPQDIADVLGEAPRLPDGSDATAPRASGTLKAHY
APSTPLALLPFGALETLLAARHVDERVALVARVSRAGHWADAEGVHFVAAPEDPHVYARELYGLLRALDRANVTRILIEK
LPDTIEWIAVNDRLGRAAAAFEAQG

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=195, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI2367210, Length=165, Percent_Identity=32.1212121212121, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=390, Percent_Identity=32.0512820512821, Blast_Score=145, Evalue=6e-36,
Organism=Drosophila melanogaster, GI78707274, Length=214, Percent_Identity=28.0373831775701, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 36384; Mature: 36253

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDQQKAAEGALPVSAAQIEHAAALLDAGELVAFPTETVYGLGGDAENPDAVARIYAAKG
CCCHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCHHEEECCCCCCCHHHHHHHHHHCC
RPANHPVIVHLAPQGDPNYWVEHLPADAQRLIDAFWPGPLTLILKRAARIPAAVSGGQDS
CCCCCCEEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCC
VGLRCPSHPVAQALLEAFSALRSGHGGVAAPSANRFGHVSPTTAQHVRDEFGDTIHVLDG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEC
GASDVGIESTILDLSRGFPALLRPGRVTPQDIADVLGEAPRLPDGSDATAPRASGTLKAH
CCCCCCHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
YAPSTPLALLPFGALETLLAARHVDERVALVARVSRAGHWADAEGVHFVAAPEDPHVYAR
ECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
ELYGLLRALDRANVTRILIEKLPDTIEWIAVNDRLGRAAAAFEAQG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCC
>Mature Secondary Structure 
PDQQKAAEGALPVSAAQIEHAAALLDAGELVAFPTETVYGLGGDAENPDAVARIYAAKG
CCHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCHHEEECCCCCCCHHHHHHHHHHCC
RPANHPVIVHLAPQGDPNYWVEHLPADAQRLIDAFWPGPLTLILKRAARIPAAVSGGQDS
CCCCCCEEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCC
VGLRCPSHPVAQALLEAFSALRSGHGGVAAPSANRFGHVSPTTAQHVRDEFGDTIHVLDG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEC
GASDVGIESTILDLSRGFPALLRPGRVTPQDIADVLGEAPRLPDGSDATAPRASGTLKAH
CCCCCCHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
YAPSTPLALLPFGALETLLAARHVDERVALVARVSRAGHWADAEGVHFVAAPEDPHVYAR
ECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
ELYGLLRALDRANVTRILIEKLPDTIEWIAVNDRLGRAAAAFEAQG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]