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The map label for this gene is fabF [H]

Identifier: 91784852

GI number: 91784852

Start: 3852060

End: 3853286

Strand: Reverse

Name: fabF [H]

Synonym: Bxe_A0940

Alternate gene names: 91784852

Gene position: 3853286-3852060 (Counterclockwise)

Preceding gene: 91784853

Following gene: 91784851

Centisome position: 78.71

GC content: 66.01

Gene sequence:

>1227_bases
ATGAAGCGCGTCGTCATTACCGGCATGGGCGGCGTCACGGCATTGGGCGACAGCTGGGACGTGATCGAAACGCGTCTGAG
GAGCGGCGTGAACGCCGTGCGGCGCATGCCCGAATGGGACTACTTCGAGTCGCTGCATACGCGGCTTGCGTGTCCGCTGC
CGGGGTTCACGATGCCCGCGCATTATCCGCGCAAGAAGACCCGCTCGATGGGACCGGTCTCGATGTACTCGGTGCGCGCG
AGCGAACTGGCGCTCGCCGACGCGGGCCTCGCCGACGACGCCACCATCAAGGACGGCCGCATGGGCGTCGCGTACGGTTC
GTCGTCGGGCTCGGTGCAGCCGATCCGCGCTTTCGGCACGATGCTCGAAACCGGCTCGATGAGCGACGTCACCTCCAACA
GCTACGTGCAGATGATGCCGCACACCACCGCGGTCAACGTCAGCCTGTTCTGGGATCTGAAAGGGCGGATCATTCCGACC
TCGTGCGCGTGCGCCTCGGGCAGCCAGGCAATCGGCTATGCGTATGAAGCGATCCAGACCGGCAAGCAGACGCTGATGCT
GGCGGGCGGCGCGGAGGAACTGTCGGGCCCGGCGGTCGCCGTGTTCGATACGCTGTACGCCACCAGCACGCGCAACGACG
AGCCGCATCTGACGCCGCGTCCGTTCGACGCCGCGCGCGACGGCCTCGTGGTCGGCGAAGGCGCGGCCACCCTGGTGCTC
GAAGAATACGGGCACGCGGTGGCGCGCGGTGCGCGGATTCACGCGGAGATCGTCGGCTTCGGCTGCAATTCGGACGGCGC
GCATATGACGCAGCCGACCGCCGAAACAATGGCGCTCGCGATGCAACTCGCGCTCAGGGATGCTCAGCTCGCGCCTGAAG
CGATTGCCTACGTGAATGCGCACGGCACCTCGACGGATCGCGGCGATATTGCCGAAAGCCACGCGACCGCGCAGACCTTC
GGCGCGCACATGCCGATCAGTTCGCTCAAGAGCTATGTCGGCCATACGCTCGGCGCGTGCGGCGCGCTCGAAGCCTGGTG
GACCATCGAGATGATGAAGCGCAACTGGTATGCGCCGACCTTGAACCTGACCCGCGTCGATCCGGCCTGCGCGCCGCTCG
ATTACATCGCCGGCACGGGCCGGCAGATCGATGCCGAATACGTGATGAGCAACAACTTCGCGTTCGGCGGCATCAACACG
TCGCTGATTTTCAGGCGCGTTCGATGA

Upstream 100 bases:

>100_bases
GCCAGCCCGCCGAGGTGGCCTCCGTGGTCAGCTTCCTGATGTCGGATGCGGCCTCGTATGTCACGCGCCAGGTGATCGGC
GTGAACGGCGGGATGATCTG

Downstream 100 bases:

>100_bases
GCATGGCGCTGCAACGCGTGGTCGTGACCGGTATGGGGATCGTGTCGTGTCTCGGCAATACGCTCGACGAAGTTGCCTCG
GCGTTGCGCGCGGGCCGCTC

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKRVVITGMGGVTALGDSWDVIETRLRSGVNAVRRMPEWDYFESLHTRLACPLPGFTMPAHYPRKKTRSMGPVSMYSVRA
SELALADAGLADDATIKDGRMGVAYGSSSGSVQPIRAFGTMLETGSMSDVTSNSYVQMMPHTTAVNVSLFWDLKGRIIPT
SCACASGSQAIGYAYEAIQTGKQTLMLAGGAEELSGPAVAVFDTLYATSTRNDEPHLTPRPFDAARDGLVVGEGAATLVL
EEYGHAVARGARIHAEIVGFGCNSDGAHMTQPTAETMALAMQLALRDAQLAPEAIAYVNAHGTSTDRGDIAESHATAQTF
GAHMPISSLKSYVGHTLGACGALEAWWTIEMMKRNWYAPTLNLTRVDPACAPLDYIAGTGRQIDAEYVMSNNFAFGGINT
SLIFRRVR

Sequences:

>Translated_408_residues
MKRVVITGMGGVTALGDSWDVIETRLRSGVNAVRRMPEWDYFESLHTRLACPLPGFTMPAHYPRKKTRSMGPVSMYSVRA
SELALADAGLADDATIKDGRMGVAYGSSSGSVQPIRAFGTMLETGSMSDVTSNSYVQMMPHTTAVNVSLFWDLKGRIIPT
SCACASGSQAIGYAYEAIQTGKQTLMLAGGAEELSGPAVAVFDTLYATSTRNDEPHLTPRPFDAARDGLVVGEGAATLVL
EEYGHAVARGARIHAEIVGFGCNSDGAHMTQPTAETMALAMQLALRDAQLAPEAIAYVNAHGTSTDRGDIAESHATAQTF
GAHMPISSLKSYVGHTLGACGALEAWWTIEMMKRNWYAPTLNLTRVDPACAPLDYIAGTGRQIDAEYVMSNNFAFGGINT
SLIFRRVR
>Mature_408_residues
MKRVVITGMGGVTALGDSWDVIETRLRSGVNAVRRMPEWDYFESLHTRLACPLPGFTMPAHYPRKKTRSMGPVSMYSVRA
SELALADAGLADDATIKDGRMGVAYGSSSGSVQPIRAFGTMLETGSMSDVTSNSYVQMMPHTTAVNVSLFWDLKGRIIPT
SCACASGSQAIGYAYEAIQTGKQTLMLAGGAEELSGPAVAVFDTLYATSTRNDEPHLTPRPFDAARDGLVVGEGAATLVL
EEYGHAVARGARIHAEIVGFGCNSDGAHMTQPTAETMALAMQLALRDAQLAPEAIAYVNAHGTSTDRGDIAESHATAQTF
GAHMPISSLKSYVGHTLGACGALEAWWTIEMMKRNWYAPTLNLTRVDPACAPLDYIAGTGRQIDAEYVMSNNFAFGGINT
SLIFRRVR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=34.8557692307692, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI41872631, Length=355, Percent_Identity=27.6056338028169, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI223972627, Length=170, Percent_Identity=37.0588235294118, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1787337, Length=416, Percent_Identity=38.4615384615385, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1788663, Length=415, Percent_Identity=35.6626506024096, Blast_Score=228, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=32.5301204819277, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71983535, Length=263, Percent_Identity=37.2623574144487, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17550940, Length=288, Percent_Identity=26.7361111111111, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=365, Percent_Identity=26.5753424657534, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=31.8385650224215, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24644341, Length=422, Percent_Identity=36.4928909952607, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI221330659, Length=364, Percent_Identity=23.6263736263736, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920632, Length=364, Percent_Identity=23.6263736263736, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24581345, Length=428, Percent_Identity=23.3644859813084, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43660; Mature: 43660

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVVITGMGGVTALGDSWDVIETRLRSGVNAVRRMPEWDYFESLHTRLACPLPGFTMPA
CCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCCCCCC
HYPRKKTRSMGPVSMYSVRASELALADAGLADDATIKDGRMGVAYGSSSGSVQPIRAFGT
CCCCHHHCCCCCEEEEEECHHHHEEECCCCCCCCEECCCCEEEEECCCCCCCCHHHHHHH
MLETGSMSDVTSNSYVQMMPHTTAVNVSLFWDLKGRIIPTSCACASGSQAIGYAYEAIQT
HHCCCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHC
GKQTLMLAGGAEELSGPAVAVFDTLYATSTRNDEPHLTPRPFDAARDGLVVGEGAATLVL
CCEEEEEECCHHHHCCCEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEHH
EEYGHAVARGARIHAEIVGFGCNSDGAHMTQPTAETMALAMQLALRDAQLAPEAIAYVNA
HHHCHHHHCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
HGTSTDRGDIAESHATAQTFGAHMPISSLKSYVGHTLGACGALEAWWTIEMMKRNWYAPT
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEEHHCCCCCCC
LNLTRVDPACAPLDYIAGTGRQIDAEYVMSNNFAFGGINTSLIFRRVR
CEEEECCCCCCCHHHHCCCCCEECCEEEEECCEEECCCCHHHEEEECC
>Mature Secondary Structure
MKRVVITGMGGVTALGDSWDVIETRLRSGVNAVRRMPEWDYFESLHTRLACPLPGFTMPA
CCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCCCCCC
HYPRKKTRSMGPVSMYSVRASELALADAGLADDATIKDGRMGVAYGSSSGSVQPIRAFGT
CCCCHHHCCCCCEEEEEECHHHHEEECCCCCCCCEECCCCEEEEECCCCCCCCHHHHHHH
MLETGSMSDVTSNSYVQMMPHTTAVNVSLFWDLKGRIIPTSCACASGSQAIGYAYEAIQT
HHCCCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHC
GKQTLMLAGGAEELSGPAVAVFDTLYATSTRNDEPHLTPRPFDAARDGLVVGEGAATLVL
CCEEEEEECCHHHHCCCEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEHH
EEYGHAVARGARIHAEIVGFGCNSDGAHMTQPTAETMALAMQLALRDAQLAPEAIAYVNA
HHHCHHHHCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEC
HGTSTDRGDIAESHATAQTFGAHMPISSLKSYVGHTLGACGALEAWWTIEMMKRNWYAPT
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEEHHCCCCCCC
LNLTRVDPACAPLDYIAGTGRQIDAEYVMSNNFAFGGINTSLIFRRVR
CEEEECCCCCCCHHHHCCCCCEECCEEEEECCEEECCCCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]