BacMap

Definition	Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession	NC_007951
Length	4,895,836

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 91784853

GI number: 91784853

Start: 3853286

End: 3854011

Strand: Reverse

Name: fabG [H]

Synonym: Bxe_A0939

Alternate gene names: 91784853

Gene position: 3854011-3853286 (Counterclockwise)

Preceding gene: 91784854

Following gene: 91784852

Centisome position: 78.72

GC content: 67.63

Gene sequence:

>726_bases
ATGAGCCGGCGTGTTCTCGTTACCGGCGCAAGCCGTGGCATTGGCCGCGCGATTGCGTACAAGTTGGCCGCCGACGGCTT
CGCGGTCTCCGTGCATTGCCGCACGGGGCGCAGCGAGGCCGACGCGGTTGCCACGGGTATCGCCGCGCAGGGCGGCACGG
CGCGCGTGTTGCAGTTCGACGTGCGCGAGCGCGCCGTGTGCCGCGAAGTGCTCGAAGCCGACGTCGCGGCGAACGGCCCG
TATTACGGCATCGTGTGCAGCGCGGGCGTGACCCGCGACGCGGCGTTCCCCGCGCTCAGCGGGGAAGACTGGGACGTGGT
GATCGAAACCGGACTCGACTCGTTCTACAACGTCGTCCATCCGTTGACCATGCCGATGGTGCGGGCCCGCCAGGGCGGCC
GTATCGTCACGATCGCTTCGGTGTCCGGCGTAATGGGCAATCGCGGGCAGGTGAACTACAGCGCGGCGAAAGCCGGCCTG
ATCGGCGCGACCAAGGCGCTCGCCGTCGAACTGGCGACGCGCAACATCACCGTCAATTGTGTCGCGCCGGGTTTGATCGA
AACCGGCATGCTCGACGAGCTGCCGCTCGAACAGGTGTTGAAGACGGTGCCGATGAACCGCGTCGGCCAGCCCGCCGAGG
TGGCCTCCGTGGTCAGCTTCCTGATGTCGGATGCGGCCTCGTATGTCACGCGCCAGGTGATCGGCGTGAACGGCGGGATG
ATCTGA

Upstream 100 bases:

>100_bases
AATGCACGATCCGGCATGGCGGCGCGGACTGCGCGGAAGCCGTCATTAAGGTTTTTCAACCAGCTGATTTTCAGTCATTC
ATCGAAGGGAGTTTCAGTTC

Downstream 100 bases:

>100_bases
TGAAGCGCGTCGTCATTACCGGCATGGGCGGCGTCACGGCATTGGGCGACAGCTGGGACGTGATCGAAACGCGTCTGAGG
AGCGGCGTGAACGCCGTGCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSRRVLVTGASRGIGRAIAYKLAADGFAVSVHCRTGRSEADAVATGIAAQGGTARVLQFDVRERAVCREVLEADVAANGP
YYGIVCSAGVTRDAAFPALSGEDWDVVIETGLDSFYNVVHPLTMPMVRARQGGRIVTIASVSGVMGNRGQVNYSAAKAGL
IGATKALAVELATRNITVNCVAPGLIETGMLDELPLEQVLKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGM
I

Sequences:

>Translated_241_residues
MSRRVLVTGASRGIGRAIAYKLAADGFAVSVHCRTGRSEADAVATGIAAQGGTARVLQFDVRERAVCREVLEADVAANGP
YYGIVCSAGVTRDAAFPALSGEDWDVVIETGLDSFYNVVHPLTMPMVRARQGGRIVTIASVSGVMGNRGQVNYSAAKAGL
IGATKALAVELATRNITVNCVAPGLIETGMLDELPLEQVLKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGM
I
>Mature_240_residues
SRRVLVTGASRGIGRAIAYKLAADGFAVSVHCRTGRSEADAVATGIAAQGGTARVLQFDVRERAVCREVLEADVAANGPY
YGIVCSAGVTRDAAFPALSGEDWDVVIETGLDSFYNVVHPLTMPMVRARQGGRIVTIASVSGVMGNRGQVNYSAAKAGLI
GATKALAVELATRNITVNCVAPGLIETGMLDELPLEQVLKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGMI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=35.6275303643725, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=34.375, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=35, Blast_Score=120, Evalue=9e-28,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=32.2709163346614, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4504505, Length=189, Percent_Identity=37.5661375661376, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI19923817, Length=246, Percent_Identity=31.3008130081301, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=30.3643724696356, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI66933014, Length=148, Percent_Identity=31.7567567567568, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=31.0880829015544, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=30.7291666666667, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI59889578, Length=149, Percent_Identity=31.5436241610738, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=30.952380952381, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4758504, Length=149, Percent_Identity=34.2281879194631, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=27.3809523809524, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=46.218487394958, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=34.297520661157, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=31.7269076305221, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=31.1475409836066, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=29.1497975708502, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=30.8, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=28.6307053941909, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=30.241935483871, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=27.34375, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=30.2521008403361, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.4615384615385, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=30.7053941908714, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786701, Length=206, Percent_Identity=30.5825242718447, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=37.5510204081633, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=35.1239669421488, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=33.203125, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17568967, Length=234, Percent_Identity=31.6239316239316, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=29.718875502008, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=28.0155642023346, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=30.2681992337165, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=27.4193548387097, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=246, Percent_Identity=27.6422764227642, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28.8, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=29.2307692307692, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=244, Percent_Identity=26.2295081967213, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=25.4752851711027, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=25.2918287937743, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=28.2442748091603, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=26.1363636363636, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=26.615969581749, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=232, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324126, Length=186, Percent_Identity=29.5698924731183, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=32.9268292682927, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=32.1138211382114, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=30.7377049180328, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=31.1740890688259, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=30.8641975308642, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=244, Percent_Identity=29.5081967213115, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18859837, Length=242, Percent_Identity=31.404958677686, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644337, Length=116, Percent_Identity=37.9310344827586, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25112; Mature: 24981

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRVLVTGASRGIGRAIAYKLAADGFAVSVHCRTGRSEADAVATGIAAQGGTARVLQFD
CCCEEEEEECCCCHHHHHHHHEECCCEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEH
VRERAVCREVLEADVAANGPYYGIVCSAGVTRDAAFPALSGEDWDVVIETGLDSFYNVVH
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
PLTMPMVRARQGGRIVTIASVSGVMGNRGQVNYSAAKAGLIGATKALAVELATRNITVNC
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEHHHHHCCHHHHHHHHEEEEEECEEEEEE
VAPGLIETGMLDELPLEQVLKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGM
ECCCHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
I
C
>Mature Secondary Structure 
SRRVLVTGASRGIGRAIAYKLAADGFAVSVHCRTGRSEADAVATGIAAQGGTARVLQFD
CCEEEEEECCCCHHHHHHHHEECCCEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEH
VRERAVCREVLEADVAANGPYYGIVCSAGVTRDAAFPALSGEDWDVVIETGLDSFYNVVH
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
PLTMPMVRARQGGRIVTIASVSGVMGNRGQVNYSAAKAGLIGATKALAVELATRNITVNC
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEHHHHHCCHHHHHHHHEEEEEECEEEEEE
VAPGLIETGMLDELPLEQVLKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGM
ECCCHHHCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]