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The map label for this gene is fabB [H]

Identifier: 91784851

GI number: 91784851

Start: 3850822

End: 3852063

Strand: Reverse

Name: fabB [H]

Synonym: Bxe_A0941

Alternate gene names: 91784851

Gene position: 3852063-3850822 (Counterclockwise)

Preceding gene: 91784852

Following gene: 91784850

Centisome position: 78.68

GC content: 69.0

Gene sequence:

>1242_bases
ATGAGCATGGCGCTGCAACGCGTGGTCGTGACCGGTATGGGGATCGTGTCGTGTCTCGGCAATACGCTCGACGAAGTTGC
CTCGGCGTTGCGCGCGGGCCGCTCGCGCATTCAGCGGATCGACGCCTGGCGAGAGCGCGGCTTCGCTTCCCAGGTGGCGG
GCGTTGCGTCGGTTGCGCACGAACCGCCGTTTGAGCGCAAGCTCGAACGCTTCATGGGCGACACGGCGCGGTTCGCCTGT
CACGCCGCGCGCAACGCGATCAGCGACGCCGGGCTCGATGCCGCGGCGTTGCGCTCGCCGCGCGCCGGCACGGTGATCGG
TTCGGGCGTCGGCACGATGTCCACTTACGACGCGGCGATGGCAACCGCGCACGCTCGCGGTGTCGACAAGGTGCCGCCGT
ACACGGTGCCGCATGCGATGAGCAGCACCGCGTCGGCGAACGTCGCGCAGGTGTTCGGGCTCGAAGGCGTCAGCTATTCG
CCGTCATCGGCGTGTACGACCTCGGCGCTCGCGATCGGGCAGGCGATGCAGCTGATCCAGACCGGCCGCCAGCAGATCGT
GCTGGCCGGCGGCAGCGAGTCGCTGCACGACAACATGACGCTCATGTTCGACGCAATGGGCGCGCTGTCGCGCCGCTTCA
ACGACACGCCGCAGCGCGCATCGCGTCCTTATGACACGGAGCGCGACGGCTTCGTGATCGCGTCGGGTGGCGGCGTGCTG
GTGCTCGAATCGCTCGAGTACGCGCTCGCACGCGGCGCGCGCATCTACGCGGAACTCACCGGATTCGGCGACTGCACGGA
CAGCGCCGGCATGGTCGCGCCGCGCGCGGCGGGGATCGCGCGCGCCATGCGCGGCGCGCTGCATGAAGCGGGCAAGCGGC
CCGATTACGTCAACACGCACGCACCGTCGACACCGCTCGGCGATACGGAGGAATTGCGCGCGTTGAGCGAAGTGTTCGGC
GCGGCGTTCGATCGTCGCGTGCCGGCGTTTTCATCGACCAAGGGGATGACGGGGCATCCGCTCGGCGCTTGCGGCGCGCA
CGAGGCGATCTACACGCTGCTGATGATGCGTGACGGCTTCATTGCTGGCACGGCGGGCATCGACACGCCGGAGCCGGCCG
TCGACGGCATGCCGCTCGTGCGCGTCACGCGTGAGGCGCGTATCGACACGGCGATGTCGGTTTCATTCGGGTTCGGCGGC
AGTTGCGCGAGCCTGGTGTTCGAAGCATGGCAGGGCGGCTGA

Upstream 100 bases:

>100_bases
ACATCGCCGGCACGGGCCGGCAGATCGATGCCGAATACGTGATGAGCAACAACTTCGCGTTCGGCGGCATCAACACGTCG
CTGATTTTCAGGCGCGTTCG

Downstream 100 bases:

>100_bases
AACGGCCGCGACTTTAAAAAAAACGAGGGTAAGAAAAATGAAAAAAACAGCTGCATTGGGCGCACTGGCGGTGGTGGTGT
TGACGCAGGCGGGATGCGCC

Product: 3-oxoacyl-[acyl-carrier-protein] synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase I; Beta-ketoacyl-ACP synthase I; KAS I [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSMALQRVVVTGMGIVSCLGNTLDEVASALRAGRSRIQRIDAWRERGFASQVAGVASVAHEPPFERKLERFMGDTARFAC
HAARNAISDAGLDAAALRSPRAGTVIGSGVGTMSTYDAAMATAHARGVDKVPPYTVPHAMSSTASANVAQVFGLEGVSYS
PSSACTTSALAIGQAMQLIQTGRQQIVLAGGSESLHDNMTLMFDAMGALSRRFNDTPQRASRPYDTERDGFVIASGGGVL
VLESLEYALARGARIYAELTGFGDCTDSAGMVAPRAAGIARAMRGALHEAGKRPDYVNTHAPSTPLGDTEELRALSEVFG
AAFDRRVPAFSSTKGMTGHPLGACGAHEAIYTLLMMRDGFIAGTAGIDTPEPAVDGMPLVRVTREARIDTAMSVSFGFGG
SCASLVFEAWQGG

Sequences:

>Translated_413_residues
MSMALQRVVVTGMGIVSCLGNTLDEVASALRAGRSRIQRIDAWRERGFASQVAGVASVAHEPPFERKLERFMGDTARFAC
HAARNAISDAGLDAAALRSPRAGTVIGSGVGTMSTYDAAMATAHARGVDKVPPYTVPHAMSSTASANVAQVFGLEGVSYS
PSSACTTSALAIGQAMQLIQTGRQQIVLAGGSESLHDNMTLMFDAMGALSRRFNDTPQRASRPYDTERDGFVIASGGGVL
VLESLEYALARGARIYAELTGFGDCTDSAGMVAPRAAGIARAMRGALHEAGKRPDYVNTHAPSTPLGDTEELRALSEVFG
AAFDRRVPAFSSTKGMTGHPLGACGAHEAIYTLLMMRDGFIAGTAGIDTPEPAVDGMPLVRVTREARIDTAMSVSFGFGG
SCASLVFEAWQGG
>Mature_412_residues
SMALQRVVVTGMGIVSCLGNTLDEVASALRAGRSRIQRIDAWRERGFASQVAGVASVAHEPPFERKLERFMGDTARFACH
AARNAISDAGLDAAALRSPRAGTVIGSGVGTMSTYDAAMATAHARGVDKVPPYTVPHAMSSTASANVAQVFGLEGVSYSP
SSACTTSALAIGQAMQLIQTGRQQIVLAGGSESLHDNMTLMFDAMGALSRRFNDTPQRASRPYDTERDGFVIASGGGVLV
LESLEYALARGARIYAELTGFGDCTDSAGMVAPRAAGIARAMRGALHEAGKRPDYVNTHAPSTPLGDTEELRALSEVFGA
AFDRRVPAFSSTKGMTGHPLGACGAHEAIYTLLMMRDGFIAGTAGIDTPEPAVDGMPLVRVTREARIDTAMSVSFGFGGS
CASLVFEAWQGG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=419, Percent_Identity=34.1288782816229, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI41872631, Length=353, Percent_Identity=25.7790368271955, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI223972627, Length=138, Percent_Identity=39.1304347826087, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1788663, Length=406, Percent_Identity=47.7832512315271, Blast_Score=345, Evalue=3e-96,
Organism=Escherichia coli, GI1787337, Length=427, Percent_Identity=38.1733021077283, Blast_Score=233, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71983541, Length=418, Percent_Identity=31.1004784688995, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71983535, Length=263, Percent_Identity=36.1216730038023, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI212642053, Length=357, Percent_Identity=26.6106442577031, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17550940, Length=287, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=32.0627802690583, Blast_Score=192, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24644341, Length=421, Percent_Identity=36.104513064133, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI221330659, Length=346, Percent_Identity=27.4566473988439, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920632, Length=346, Percent_Identity=27.4566473988439, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24581345, Length=357, Percent_Identity=24.9299719887955, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: 24024 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 30,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 43162; Mature: 43031

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMALQRVVVTGMGIVSCLGNTLDEVASALRAGRSRIQRIDAWRERGFASQVAGVASVAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
EPPFERKLERFMGDTARFACHAARNAISDAGLDAAALRSPRAGTVIGSGVGTMSTYDAAM
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCCCHHHHHHHH
ATAHARGVDKVPPYTVPHAMSSTASANVAQVFGLEGVSYSPSSACTTSALAIGQAMQLIQ
HHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TGRQQIVLAGGSESLHDNMTLMFDAMGALSRRFNDTPQRASRPYDTERDGFVIASGGGVL
CCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEECCCCEE
VLESLEYALARGARIYAELTGFGDCTDSAGMVAPRAAGIARAMRGALHEAGKRPDYVNTH
EHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
APSTPLGDTEELRALSEVFGAAFDRRVPAFSSTKGMTGHPLGACGAHEAIYTLLMMRDGF
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
IAGTAGIDTPEPAVDGMPLVRVTREARIDTAMSVSFGFGGSCASLVFEAWQGG
EEECCCCCCCCCCCCCCCHHHHHHHHHHCHHEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SMALQRVVVTGMGIVSCLGNTLDEVASALRAGRSRIQRIDAWRERGFASQVAGVASVAH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
EPPFERKLERFMGDTARFACHAARNAISDAGLDAAALRSPRAGTVIGSGVGTMSTYDAAM
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCCCHHHHHHHH
ATAHARGVDKVPPYTVPHAMSSTASANVAQVFGLEGVSYSPSSACTTSALAIGQAMQLIQ
HHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TGRQQIVLAGGSESLHDNMTLMFDAMGALSRRFNDTPQRASRPYDTERDGFVIASGGGVL
CCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEECCCCEE
VLESLEYALARGARIYAELTGFGDCTDSAGMVAPRAAGIARAMRGALHEAGKRPDYVNTH
EHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
APSTPLGDTEELRALSEVFGAAFDRRVPAFSSTKGMTGHPLGACGAHEAIYTLLMMRDGF
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
IAGTAGIDTPEPAVDGMPLVRVTREARIDTAMSVSFGFGGSCASLVFEAWQGG
EEECCCCCCCCCCCCCCCHHHHHHHHHHCHHEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]