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The map label for this gene is tadA [H]

Identifier: 91783891

GI number: 91783891

Start: 2808913

End: 2809503

Strand: Reverse

Name: tadA [H]

Synonym: Bxe_A1920

Alternate gene names: 91783891

Gene position: 2809503-2808913 (Counterclockwise)

Preceding gene: 91783892

Following gene: 91783890

Centisome position: 57.39

GC content: 68.02

Gene sequence:

>591_bases
ATGATGGAGGCAGCGGCCGGGTCCGTGCCCGGCGATTCGCCCGCATCATCCGCGGTCTTGGAGCGCGATCGCCGCTTCAT
GGCGCTCGCACAAGCTGCCGCCGAAGAGGCGCGCGCCATCGGCGAAGTGCCCGTCGGCGCGGTGCTCGTGCGAGGCGACG
AAGTCATCGCCAAAGGTTTCAATCACCCAATCGGGGCGCACGACCCGTCTGCGCATGCGGAAATGGTCGCGTTGCGCGCC
GCGGCGCAGGCTGTCGAAAACTACCGTTTGCCGGGCTGCGAACTTTACGTGACGCTTGAGCCGTGCCTGATGTGCGCCGG
CGCGATCATGCACGCGCGCATCGCCCGTGTCGTATTCGGGGCGCGCGATCCGAAAACCGGTGCGTGTGGCAGTGTCGTCG
ATGCGTTCGCGAATCCGCAACTGAATCATCACACCACGGTGACCGGCGGCGTGCTCGAAAGCGAATGCGGCGCGGCGCTC
AAAGCGTTCTTTGCCGAACGGCGGCGCGCAAGCCGCGAAGCGCGCGTGTCGGCACGTGCCGAAGCGGGTGCCGACGCAGG
TGCCGACGCGGGCCCGGCGAAAGCGCCCTGA

Upstream 100 bases:

>100_bases
AGATTCTTTCAAATCTCACGAAGCGCCGGATGCCATGAGTTCTTCAGCCTCGGCGAATGGCGTCGCCGAACCGATCGCGA
TGGATTCCGGCACCGCCGCC

Downstream 100 bases:

>100_bases
AACAACCACGTTCAATAAGGTCCTCGCTCATGGCCGTCCATCGCACCATCGAACTGATCGCTCCGTCCGGGTATCCGCAT
GATCCGGAGGTGCTGCATCG

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MMEAAAGSVPGDSPASSAVLERDRRFMALAQAAAEEARAIGEVPVGAVLVRGDEVIAKGFNHPIGAHDPSAHAEMVALRA
AAQAVENYRLPGCELYVTLEPCLMCAGAIMHARIARVVFGARDPKTGACGSVVDAFANPQLNHHTTVTGGVLESECGAAL
KAFFAERRRASREARVSARAEAGADAGADAGPAKAP

Sequences:

>Translated_196_residues
MMEAAAGSVPGDSPASSAVLERDRRFMALAQAAAEEARAIGEVPVGAVLVRGDEVIAKGFNHPIGAHDPSAHAEMVALRA
AAQAVENYRLPGCELYVTLEPCLMCAGAIMHARIARVVFGARDPKTGACGSVVDAFANPQLNHHTTVTGGVLESECGAAL
KAFFAERRRASREARVSARAEAGADAGADAGPAKAP
>Mature_196_residues
MMEAAAGSVPGDSPASSAVLERDRRFMALAQAAAEEARAIGEVPVGAVLVRGDEVIAKGFNHPIGAHDPSAHAEMVALRA
AAQAVENYRLPGCELYVTLEPCLMCAGAIMHARIARVVFGARDPKTGACGSVVDAFANPQLNHHTTVTGGVLESECGAAL
KAFFAERRRASREARVSARAEAGADAGADAGPAKAP

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=142, Percent_Identity=38.0281690140845, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI19923945, Length=69, Percent_Identity=52.1739130434783, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI145693172, Length=162, Percent_Identity=51.2345679012346, Blast_Score=169, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=39.7959183673469, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17541138, Length=149, Percent_Identity=34.2281879194631, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=97, Percent_Identity=39.1752577319588, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=35.8620689655172, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 20142; Mature: 20142

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEAAAGSVPGDSPASSAVLERDRRFMALAQAAAEEARAIGEVPVGAVLVRGDEVIAKGF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHCC
NHPIGAHDPSAHAEMVALRAAAQAVENYRLPGCELYVTLEPCLMCAGAIMHARIARVVFG
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHC
ARDPKTGACGSVVDAFANPQLNHHTTVTGGVLESECGAALKAFFAERRRASREARVSARA
CCCCCCCCHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGADAGADAGPAKAP
HCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMEAAAGSVPGDSPASSAVLERDRRFMALAQAAAEEARAIGEVPVGAVLVRGDEVIAKGF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHCC
NHPIGAHDPSAHAEMVALRAAAQAVENYRLPGCELYVTLEPCLMCAGAIMHARIARVVFG
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHC
ARDPKTGACGSVVDAFANPQLNHHTTVTGGVLESECGAALKAFFAERRRASREARVSARA
CCCCCCCCHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGADAGADAGPAKAP
HCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]