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The map label for this gene is ldcA [H]

Identifier: 91783890

GI number: 91783890

Start: 2807957

End: 2808883

Strand: Reverse

Name: ldcA [H]

Synonym: Bxe_A1921

Alternate gene names: 91783890

Gene position: 2808883-2807957 (Counterclockwise)

Preceding gene: 91783891

Following gene: 91783889

Centisome position: 57.37

GC content: 64.83

Gene sequence:

>927_bases
ATGGCCGTCCATCGCACCATCGAACTGATCGCTCCGTCCGGGTATCCGCATGATCCGGAGGTGCTGCATCGCGCGCTGCA
ACGTTTGCATGCGCAGGGACATCGTGTCGAGGGCGCGGAGGCGGCGAAGCGCCGCTACCAGCGTTTCGCGGGCACGGACG
GCCAGCGCGCCGCCGATCTGAACCGGCTCGCCGACCCGTCGCGCGAGTTGCCGGACATCGTGCTGGCCGTGCGCGGCGGC
TACGGCGCGGTGCGCATTCTGCACGGGCTCGACTACGAAGGGCTGCAACGGCGGTTGACCGATCAGCCGGTCGCTCTGGT
GGGGCACAGCGATTTCACCGCGATCCAGCTTGCGTTGCTGGCGCGCGCCGGCGTGAAGACCTTCGGCGGCCCGATGGTGA
TGAGCGACTTCGGCGCTGAGGAACTCAGCGAATTCACCATGCAGCACTTCTGGTCCGCGTTGACAAAGCCGACCATGACG
GTTTCGAGCAACACGCCGCAGGCGCAGCCGGTGGACGTCTCGGGCATGTTGTGGGGGGGTAACCTGGCGGTGCTGGTCTC
GCTGATCGGCACGCCGTATATGCCGCCGGTGAAGGGCGGCATCCTGTTCATCGAGGACGTCAACGAACAGCCGTTCCGGG
TCGAGCGGATGATTTATCAACTGCACCTGTCCGGCATCCTCGCGCAGCAACAGGCGCTCGTGCTGGGCGACTTCTCCGGC
GCCAAAGCGTACGACTACGACAACGGCTACGATCTGCATGCAGTGATCGAGCAGGCGAGGTCGGTGATCGGCATTCCGAT
CGTCACCGGCCTGCAATTCGGGCATGTTCGCAACATGCTGACGCTGCCGGTTGGCGCGAACGCGCATCTGGTTGCCGACG
CACACGGATTCAGACTGAGCTTGTCGGACTATCCATACCTCGCCTGA

Upstream 100 bases:

>100_bases
CGCGCGTGTCGGCACGTGCCGAAGCGGGTGCCGACGCAGGTGCCGACGCGGGCCCGGCGAAAGCGCCCTGAAACAACCAC
GTTCAATAAGGTCCTCGCTC

Downstream 100 bases:

>100_bases
AGCGGCAGAGAAGGGAAGCGGGCAATCGCCCGTTTTCTTTCAGTTCAATATCGCAACTAACGGTCATATCAAAAGACGGC
CGCCAACAGGATGCTCCGTG

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAVHRTIELIAPSGYPHDPEVLHRALQRLHAQGHRVEGAEAAKRRYQRFAGTDGQRAADLNRLADPSRELPDIVLAVRGG
YGAVRILHGLDYEGLQRRLTDQPVALVGHSDFTAIQLALLARAGVKTFGGPMVMSDFGAEELSEFTMQHFWSALTKPTMT
VSSNTPQAQPVDVSGMLWGGNLAVLVSLIGTPYMPPVKGGILFIEDVNEQPFRVERMIYQLHLSGILAQQQALVLGDFSG
AKAYDYDNGYDLHAVIEQARSVIGIPIVTGLQFGHVRNMLTLPVGANAHLVADAHGFRLSLSDYPYLA

Sequences:

>Translated_308_residues
MAVHRTIELIAPSGYPHDPEVLHRALQRLHAQGHRVEGAEAAKRRYQRFAGTDGQRAADLNRLADPSRELPDIVLAVRGG
YGAVRILHGLDYEGLQRRLTDQPVALVGHSDFTAIQLALLARAGVKTFGGPMVMSDFGAEELSEFTMQHFWSALTKPTMT
VSSNTPQAQPVDVSGMLWGGNLAVLVSLIGTPYMPPVKGGILFIEDVNEQPFRVERMIYQLHLSGILAQQQALVLGDFSG
AKAYDYDNGYDLHAVIEQARSVIGIPIVTGLQFGHVRNMLTLPVGANAHLVADAHGFRLSLSDYPYLA
>Mature_307_residues
AVHRTIELIAPSGYPHDPEVLHRALQRLHAQGHRVEGAEAAKRRYQRFAGTDGQRAADLNRLADPSRELPDIVLAVRGGY
GAVRILHGLDYEGLQRRLTDQPVALVGHSDFTAIQLALLARAGVKTFGGPMVMSDFGAEELSEFTMQHFWSALTKPTMTV
SSNTPQAQPVDVSGMLWGGNLAVLVSLIGTPYMPPVKGGILFIEDVNEQPFRVERMIYQLHLSGILAQQQALVLGDFSGA
KAYDYDNGYDLHAVIEQARSVIGIPIVTGLQFGHVRNMLTLPVGANAHLVADAHGFRLSLSDYPYLA

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=302, Percent_Identity=49.6688741721854, Blast_Score=290, Evalue=6e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 33610; Mature: 33479

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHRTIELIAPSGYPHDPEVLHRALQRLHAQGHRVEGAEAAKRRYQRFAGTDGQRAADL
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHH
NRLADPSRELPDIVLAVRGGYGAVRILHGLDYEGLQRRLTDQPVALVGHSDFTAIQLALL
HHHCCCCCCCCEEEEEEECCCCEEEHHHCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHH
ARAGVKTFGGPMVMSDFGAEELSEFTMQHFWSALTKPTMTVSSNTPQAQPVDVSGMLWGG
HHHCHHHCCCCEEEHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECC
NLAVLVSLIGTPYMPPVKGGILFIEDVNEQPFRVERMIYQLHLSGILAQQQALVLGDFSG
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCC
AKAYDYDNGYDLHAVIEQARSVIGIPIVTGLQFGHVRNMLTLPVGANAHLVADAHGFRLS
CEECCCCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHCCEEEECCCCCEEEEEECCCCEEE
LSDYPYLA
CCCCCCCC
>Mature Secondary Structure 
AVHRTIELIAPSGYPHDPEVLHRALQRLHAQGHRVEGAEAAKRRYQRFAGTDGQRAADL
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHH
NRLADPSRELPDIVLAVRGGYGAVRILHGLDYEGLQRRLTDQPVALVGHSDFTAIQLALL
HHHCCCCCCCCEEEEEEECCCCEEEHHHCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHH
ARAGVKTFGGPMVMSDFGAEELSEFTMQHFWSALTKPTMTVSSNTPQAQPVDVSGMLWGG
HHHCHHHCCCCEEEHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECC
NLAVLVSLIGTPYMPPVKGGILFIEDVNEQPFRVERMIYQLHLSGILAQQQALVLGDFSG
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCC
AKAYDYDNGYDLHAVIEQARSVIGIPIVTGLQFGHVRNMLTLPVGANAHLVADAHGFRLS
CEECCCCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHCCEEEECCCCCEEEEEECCCCEEE
LSDYPYLA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]