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The map label for this gene is fabR [H]

Identifier: 91783854

GI number: 91783854

Start: 2770005

End: 2770694

Strand: Reverse

Name: fabR [H]

Synonym: Bxe_A1957

Alternate gene names: 91783854

Gene position: 2770694-2770005 (Counterclockwise)

Preceding gene: 91783858

Following gene: 91783850

Centisome position: 56.59

GC content: 64.93

Gene sequence:

>690_bases
ATGAAACCCGTCCCCGAAGCGGCAGCCGCCGCCGAGCATGGTGTTGCCGCCGGCCAGGAATTGCCGGCCGGCAAGCGCAA
GCTGATCGAGGCCGCGTTGCGGCTGACCGCGGGCGGCCGCAGTTTCACGAGCCTGGGTTTGCGCGAGCTGGCTCGCGAGG
CGGGGCTCAATCCCAATACCTTCTATCGTCATTTCGACACGCTCGACGATCTGGCGCGCGAAGCCGTCGAGTCGGTGAGC
CGCCGTTTGCGGCCGATGTTGCGGCGTGAGCGCTGGCTCGCCGCGCACGACGAGCCGCATAGCGTGCCACGTCGTGCGTG
CGTCGCGTTCTTTGCCTTCACGCTGGAAAACCGCGAGGCGTTTCTGAGCGCGCTGGCCGAATATCACGGCACATCGCGGG
CGTTGCGCGAAGCCGTGCGCGCCAACCTGCACGAGGTGTCGGCGGAAATGGCCGACGACGTGGTTGAACTGGAATTGATG
CCGACGCTCTCGCGCGAAACAGTCGATGAAGTCTGCACGCAGATCGTGCTGCAACTGTTCCATCTCTCGGCTGAATATAT
CGATGCAAACGAGGCGCGCCGCGATGCGCTGATCGCGTATGCGGAGCGTTTCATCGTCAGGCTGTTTGCGGGCGCGGTGT
TGCTGGCGCAGCATGAGGCGGGCAGGGCGCCTTTATCGATGCGTGCCTGA

Upstream 100 bases:

>100_bases
ATTTCAGCATAACGCGCAGGGTAGACAACTGTGCACCTGACGTCAAGATCGTTTAGAGTACTGCTATTAAACGTGCATGG
CGCGCATCGATTGAAATCAC

Downstream 100 bases:

>100_bases
AGCCTGAAACGAAGGGCCATAAAGAAACAGGCTCCGTGTGACGGAGCCTGTTTCTTTCGCTTGCAGATGCCTGGCTGAAC
GGGCCGGATTTCGGCCGCTG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKPVPEAAAAAEHGVAAGQELPAGKRKLIEAALRLTAGGRSFTSLGLRELAREAGLNPNTFYRHFDTLDDLAREAVESVS
RRLRPMLRRERWLAAHDEPHSVPRRACVAFFAFTLENREAFLSALAEYHGTSRALREAVRANLHEVSAEMADDVVELELM
PTLSRETVDEVCTQIVLQLFHLSAEYIDANEARRDALIAYAERFIVRLFAGAVLLAQHEAGRAPLSMRA

Sequences:

>Translated_229_residues
MKPVPEAAAAAEHGVAAGQELPAGKRKLIEAALRLTAGGRSFTSLGLRELAREAGLNPNTFYRHFDTLDDLAREAVESVS
RRLRPMLRRERWLAAHDEPHSVPRRACVAFFAFTLENREAFLSALAEYHGTSRALREAVRANLHEVSAEMADDVVELELM
PTLSRETVDEVCTQIVLQLFHLSAEYIDANEARRDALIAYAERFIVRLFAGAVLLAQHEAGRAPLSMRA
>Mature_229_residues
MKPVPEAAAAAEHGVAAGQELPAGKRKLIEAALRLTAGGRSFTSLGLRELAREAGLNPNTFYRHFDTLDDLAREAVESVS
RRLRPMLRRERWLAAHDEPHSVPRRACVAFFAFTLENREAFLSALAEYHGTSRALREAVRANLHEVSAEMADDVVELELM
PTLSRETVDEVCTQIVLQLFHLSAEYIDANEARRDALIAYAERFIVRLFAGAVLLAQHEAGRAPLSMRA

Specific function: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693209, Length=196, Percent_Identity=38.265306122449, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25441; Mature: 25441

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVPEAAAAAEHGVAAGQELPAGKRKLIEAALRLTAGGRSFTSLGLRELAREAGLNPNT
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHH
FYRHFDTLDDLAREAVESVSRRLRPMLRRERWLAAHDEPHSVPRRACVAFFAFTLENREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FLSALAEYHGTSRALREAVRANLHEVSAEMADDVVELELMPTLSRETVDEVCTQIVLQLF
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HLSAEYIDANEARRDALIAYAERFIVRLFAGAVLLAQHEAGRAPLSMRA
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKPVPEAAAAAEHGVAAGQELPAGKRKLIEAALRLTAGGRSFTSLGLRELAREAGLNPNT
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHH
FYRHFDTLDDLAREAVESVSRRLRPMLRRERWLAAHDEPHSVPRRACVAFFAFTLENREA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FLSALAEYHGTSRALREAVRANLHEVSAEMADDVVELELMPTLSRETVDEVCTQIVLQLF
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HLSAEYIDANEARRDALIAYAERFIVRLFAGAVLLAQHEAGRAPLSMRA
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA