| Definition | Burkholderia xenovorans LB400 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007951 |
| Length | 4,895,836 |
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The map label for this gene is mrcA [H]
Identifier: 91783850
GI number: 91783850
Start: 2763886
End: 2766396
Strand: Reverse
Name: mrcA [H]
Synonym: Bxe_A1961
Alternate gene names: 91783850
Gene position: 2766396-2763886 (Counterclockwise)
Preceding gene: 91783854
Following gene: 91783849
Centisome position: 56.51
GC content: 64.36
Gene sequence:
>2511_bases ATTCCAGTCATGCCAATCATCAAACGACCGCATTCATCCAATTCTCCGTCTGGTGAAGACCGGGATTCCTACCAACGCAC GCCGGGACGCAATGCAGCTTCGCGCGAGGCCGGGGCCGGCCGCCGTTCCATCGGCGTGACCATCGCCATCTGGTTCGCCG GCCTGATCGCGACCATCGCGGTGGTGAGTGCGCTGATCATCGGCTATGCGCTGGTGGTGATGGGCCCGCAACTGCCGTCG CTCGACGCGCTCACCGACTATCGCCCGAAGGTGCCGCTGCGCGTCTATACCGCGGACCATGTGCTGATCGGCGAATTCGG CGAAGAGCGGCGCAGTCTCGTGCGCTTCCAGGACATTCCCGATCAGATGAAGAAAGCGGTGCTCGCGATCGAAGACTATC GCTTCTACGAGCACGGCGGCGTCGACTTCATCGGTATTCTGCGGGCAGGTGTCTCCGATCTTTCGCACGGCGGCGCTTCG CAGGGCGCGAGTACGATCACCATGCAGGTGGCGCGCAACTTCTTCCTGTCGAGTGAGAAGACCTACACGCGCAAGATCTA CGAAATGCTGCTCGCGTACAAGATCGAGCGCGCGCTCACCAAGGATCAGATTCTCGAGCTGTACATGAACCAGATTTATC TGGGTGAGCGCGCCTACGGTTTCGCCGCGGCCGCGCGCGTGTACTTCGGCAAGGATCTGAAGGACATCACGCTGGCGGAA TCGGCGATGCTGGCGGGCTTGCCGAAGGCGCCCTCCGCGTATAACCCGGTGGTCAATCCGAAGCGCGCGAAGATCCGTCA GGAGTACATTCTGCGGCGCATGCTCGAGCTCAGATACATCAGCCAGGAGCAGTACGACCAGGCGGTGAAGGAAGAGATCC ACACCAAGAATCCGGGCAACGAATACAGCGTGCACGCCGAGTACATTGCCGAAATGGTCCGGCAGATGATGTACGCCCAG TACAAGGACGAAACCTATACGCGCGGCCTGAACGTCACCACCACGATCGACTCCGCCGACCAGGACGCCGCCTATCGCGC CGTGCGCAAGGGCGTGATGGATTACGAGCGGCGGCACGGGTATCGCGGGCCGGAGGGCTTCGTGCAGCTGCCCGCGCCGG GTGACGACCGCGATCAGACGATCGACGACGCGCTCACCGATCACCCCGACAACGGCGAGATCATCGCCGCCGTGGTGACG GACGCGAGTCCGAAGCAGGTCAAGGCGCAACTGGTGGACGGCACGCAGGTGGCGATCAGCGGCGACGGTCTGCGCTTCGT AGCGGGCGCGCTGAGCACGCGCGCGGCGGCGGCCACGAAGATCAGGCCGGGCTCGATCGTGCGTCTGGTTGCCGACGACA AGGGCAACTGGCAGATCACGCAACTGCCGCAGGTGGAAGGCGCGCTGGTATCGCTCACGCCGCAGGACGGCGCGATTCGC GCACTGGTGGGCGGTTTCGACTTCAACAAGAACAAGTTCAACCACGTCACGCAGGCGTGGCGCCAGCCGGGTTCGAGCTT CAAGCCATTCATTTACTCGGCGGCGCTGGACAAAGGTCTCGGACCGGCCACGATCATCAACGACGCGCCGCTGTATTTCC CGTCCAGCACACCGGGCGGCGACGCGTGGGAGCCGAAGGACGACGACCAGCCGGACGGTCCGATGCCGATGCGTCTCGCG TTGCAGAAGTCGAAGAACCTGGTGTCGATCCGTATTCTGTCGTTCATCGGCACCAGATACGCGCAGGACTTCGTCACGCA GCGTTTCGGCTTCGACGCCGACAAGACCCCGCCGTACCTGCCGATGGCGCTCGGCGCGGGCCTCGTCACACCGTTGCAGT CGGCGGGTGCGTATTCGGTGTTCGCCAACGGCGGCTACCGGATCAATCCGTATCTGATCAACGAGGTGACGGACGCGCGC GGCGAGCCGCTCTCCAGAGCGCAGCCGCTCACAGCCGGTCGCGATGCGCCGCGCACGCTCGAACCGCGCAACGCGTACAT CATGAACAGCCTGCTGCATTCGGTGGCGACCGCCGGCACGGGCGCGGGCACCAACGTGCTGCATCGTTCGGACCTGCAGG GCAAGACGGGTACCACCAACGACGCGAAGGACGGCTGGTTTGCTGGTTATCAGCAGTCGCTCGTGGCGGTGGCGTGGATG GGTTACGACCAGCCCAAGAGCCTCGGCAGCCGCGAATTCGGCGCGCAACTGGCATTGCCGATCTGGGTGGAATACATGCA GCGCGCGTTGCGCGGCGTGCCGCAAAGCGAACCGGCGCAGCCGGACGGCGTGACATCCGTCGACGGTGAGCTGTTCTATA CAGACATGACGCCGGGCAACGGCTTCGTGGCCAGCATCGGTCTGGATTCGGCGAACCCCACCGCGGGCGCGAGCGATGCG GTCGGCGGCGTGGGACCCGCGGGCATGACGCCGCCGGCGGTACCGCCGCCGAGCGTCTCGTCGAACGAGAAGAAGCAGAT CATGGATCTGTTCGAGTCGAACAAGCCCTGA
Upstream 100 bases:
>100_bases AAGGCCGTGCGGTGGTTCGCGCCTCAGGCTACGATGCTCGATCACGATCCATGTGCGCGCGAGGAGCGCGTGCAGAAAGG CGTTCGGTTATGCGCCCACT
Downstream 100 bases:
>100_bases TGTCCCGCACGGGATGTCTTTGAGGGGCAGCAGGTGTGCGCGGGCCGCGTGAACTTGGCGGGGCCGCGCACGCATTCTTT GTAAAACAGCAGGGAATCGC
Product: putative penicillin-binding (peptidoglycan synthetase) transmembrane protein, mrcA
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 836; Mature: 835
Protein sequence:
>836_residues MPVMPIIKRPHSSNSPSGEDRDSYQRTPGRNAASREAGAGRRSIGVTIAIWFAGLIATIAVVSALIIGYALVVMGPQLPS LDALTDYRPKVPLRVYTADHVLIGEFGEERRSLVRFQDIPDQMKKAVLAIEDYRFYEHGGVDFIGILRAGVSDLSHGGAS QGASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFAAAARVYFGKDLKDITLAE SAMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMLELRYISQEQYDQAVKEEIHTKNPGNEYSVHAEYIAEMVRQMMYAQ YKDETYTRGLNVTTTIDSADQDAAYRAVRKGVMDYERRHGYRGPEGFVQLPAPGDDRDQTIDDALTDHPDNGEIIAAVVT DASPKQVKAQLVDGTQVAISGDGLRFVAGALSTRAAAATKIRPGSIVRLVADDKGNWQITQLPQVEGALVSLTPQDGAIR ALVGGFDFNKNKFNHVTQAWRQPGSSFKPFIYSAALDKGLGPATIINDAPLYFPSSTPGGDAWEPKDDDQPDGPMPMRLA LQKSKNLVSIRILSFIGTRYAQDFVTQRFGFDADKTPPYLPMALGAGLVTPLQSAGAYSVFANGGYRINPYLINEVTDAR GEPLSRAQPLTAGRDAPRTLEPRNAYIMNSLLHSVATAGTGAGTNVLHRSDLQGKTGTTNDAKDGWFAGYQQSLVAVAWM GYDQPKSLGSREFGAQLALPIWVEYMQRALRGVPQSEPAQPDGVTSVDGELFYTDMTPGNGFVASIGLDSANPTAGASDA VGGVGPAGMTPPAVPPPSVSSNEKKQIMDLFESNKP
Sequences:
>Translated_836_residues MPVMPIIKRPHSSNSPSGEDRDSYQRTPGRNAASREAGAGRRSIGVTIAIWFAGLIATIAVVSALIIGYALVVMGPQLPS LDALTDYRPKVPLRVYTADHVLIGEFGEERRSLVRFQDIPDQMKKAVLAIEDYRFYEHGGVDFIGILRAGVSDLSHGGAS QGASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFAAAARVYFGKDLKDITLAE SAMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMLELRYISQEQYDQAVKEEIHTKNPGNEYSVHAEYIAEMVRQMMYAQ YKDETYTRGLNVTTTIDSADQDAAYRAVRKGVMDYERRHGYRGPEGFVQLPAPGDDRDQTIDDALTDHPDNGEIIAAVVT DASPKQVKAQLVDGTQVAISGDGLRFVAGALSTRAAAATKIRPGSIVRLVADDKGNWQITQLPQVEGALVSLTPQDGAIR ALVGGFDFNKNKFNHVTQAWRQPGSSFKPFIYSAALDKGLGPATIINDAPLYFPSSTPGGDAWEPKDDDQPDGPMPMRLA LQKSKNLVSIRILSFIGTRYAQDFVTQRFGFDADKTPPYLPMALGAGLVTPLQSAGAYSVFANGGYRINPYLINEVTDAR GEPLSRAQPLTAGRDAPRTLEPRNAYIMNSLLHSVATAGTGAGTNVLHRSDLQGKTGTTNDAKDGWFAGYQQSLVAVAWM GYDQPKSLGSREFGAQLALPIWVEYMQRALRGVPQSEPAQPDGVTSVDGELFYTDMTPGNGFVASIGLDSANPTAGASDA VGGVGPAGMTPPAVPPPSVSSNEKKQIMDLFESNKP >Mature_835_residues PVMPIIKRPHSSNSPSGEDRDSYQRTPGRNAASREAGAGRRSIGVTIAIWFAGLIATIAVVSALIIGYALVVMGPQLPSL DALTDYRPKVPLRVYTADHVLIGEFGEERRSLVRFQDIPDQMKKAVLAIEDYRFYEHGGVDFIGILRAGVSDLSHGGASQ GASTITMQVARNFFLSSEKTYTRKIYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFAAAARVYFGKDLKDITLAES AMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMLELRYISQEQYDQAVKEEIHTKNPGNEYSVHAEYIAEMVRQMMYAQY KDETYTRGLNVTTTIDSADQDAAYRAVRKGVMDYERRHGYRGPEGFVQLPAPGDDRDQTIDDALTDHPDNGEIIAAVVTD ASPKQVKAQLVDGTQVAISGDGLRFVAGALSTRAAAATKIRPGSIVRLVADDKGNWQITQLPQVEGALVSLTPQDGAIRA LVGGFDFNKNKFNHVTQAWRQPGSSFKPFIYSAALDKGLGPATIINDAPLYFPSSTPGGDAWEPKDDDQPDGPMPMRLAL QKSKNLVSIRILSFIGTRYAQDFVTQRFGFDADKTPPYLPMALGAGLVTPLQSAGAYSVFANGGYRINPYLINEVTDARG EPLSRAQPLTAGRDAPRTLEPRNAYIMNSLLHSVATAGTGAGTNVLHRSDLQGKTGTTNDAKDGWFAGYQQSLVAVAWMG YDQPKSLGSREFGAQLALPIWVEYMQRALRGVPQSEPAQPDGVTSVDGELFYTDMTPGNGFVASIGLDSANPTAGASDAV GGVGPAGMTPPAVPPPSVSSNEKKQIMDLFESNKP
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=834, Percent_Identity=38.8489208633094, Blast_Score=529, Evalue=1e-151, Organism=Escherichia coli, GI1786343, Length=249, Percent_Identity=37.7510040160643, Blast_Score=151, Evalue=2e-37, Organism=Escherichia coli, GI1788867, Length=228, Percent_Identity=32.4561403508772, Blast_Score=116, Evalue=7e-27, Organism=Escherichia coli, GI1789601, Length=176, Percent_Identity=34.0909090909091, Blast_Score=92, Evalue=1e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.- [C]
Molecular weight: Translated: 90956; Mature: 90825
Theoretical pI: Translated: 6.76; Mature: 6.76
Prosite motif: PS00639 THIOL_PROTEASE_HIS
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPVMPIIKRPHSSNSPSGEDRDSYQRTPGRNAASREAGAGRRSIGVTIAIWFAGLIATIA CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH VVSALIIGYALVVMGPQLPSLDALTDYRPKVPLRVYTADHVLIGEFGEERRSLVRFQDIP HHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHCCH DQMKKAVLAIEDYRFYEHGGVDFIGILRAGVSDLSHGGASQGASTITMQVARNFFLSSEK HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCH TYTRKIYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFAAAARVYFGKDLKDITLAE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH SAMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMLELRYISQEQYDQAVKEEIHTKNPGN HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC EYSVHAEYIAEMVRQMMYAQYKDETYTRGLNVTTTIDSADQDAAYRAVRKGVMDYERRHG CEEEEHHHHHHHHHHHHHHHHCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC YRGPEGFVQLPAPGDDRDQTIDDALTDHPDNGEIIAAVVTDASPKQVKAQLVDGTQVAIS CCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHEECCEEEEEE GDGLRFVAGALSTRAAAATKIRPGSIVRLVADDKGNWQITQLPQVEGALVSLTPQDGAIR CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEECCCCCCEE ALVGGFDFNKNKFNHVTQAWRQPGSSFKPFIYSAALDKGLGPATIINDAPLYFPSSTPGG EEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCCEECCCCCCCC DAWEPKDDDQPDGPMPMRLALQKSKNLVSIRILSFIGTRYAQDFVTQRFGFDADKTPPYL CCCCCCCCCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC PMALGAGLVTPLQSAGAYSVFANGGYRINPYLINEVTDARGEPLSRAQPLTAGRDAPRTL HHHHCCCHHHHHHCCCCEEEEECCCEEECCEEEECHHCCCCCCCHHCCCCCCCCCCCCCC EPRNAYIMNSLLHSVATAGTGAGTNVLHRSDLQGKTGTTNDAKDGWFAGYQQSLVAVAWM CCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEC GYDQPKSLGSREFGAQLALPIWVEYMQRALRGVPQSEPAQPDGVTSVDGELFYTDMTPGN CCCCCHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCC GFVASIGLDSANPTAGASDAVGGVGPAGMTPPAVPPPSVSSNEKKQIMDLFESNKP CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC >Mature Secondary Structure PVMPIIKRPHSSNSPSGEDRDSYQRTPGRNAASREAGAGRRSIGVTIAIWFAGLIATIA CCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH VVSALIIGYALVVMGPQLPSLDALTDYRPKVPLRVYTADHVLIGEFGEERRSLVRFQDIP HHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHCCH DQMKKAVLAIEDYRFYEHGGVDFIGILRAGVSDLSHGGASQGASTITMQVARNFFLSSEK HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCH TYTRKIYEMLLAYKIERALTKDQILELYMNQIYLGERAYGFAAAARVYFGKDLKDITLAE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH SAMLAGLPKAPSAYNPVVNPKRAKIRQEYILRRMLELRYISQEQYDQAVKEEIHTKNPGN HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC EYSVHAEYIAEMVRQMMYAQYKDETYTRGLNVTTTIDSADQDAAYRAVRKGVMDYERRHG CEEEEHHHHHHHHHHHHHHHHCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCC YRGPEGFVQLPAPGDDRDQTIDDALTDHPDNGEIIAAVVTDASPKQVKAQLVDGTQVAIS CCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHEECCEEEEEE GDGLRFVAGALSTRAAAATKIRPGSIVRLVADDKGNWQITQLPQVEGALVSLTPQDGAIR CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEECCCCCCEE ALVGGFDFNKNKFNHVTQAWRQPGSSFKPFIYSAALDKGLGPATIINDAPLYFPSSTPGG EEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCCEECCCCCCCC DAWEPKDDDQPDGPMPMRLALQKSKNLVSIRILSFIGTRYAQDFVTQRFGFDADKTPPYL CCCCCCCCCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC PMALGAGLVTPLQSAGAYSVFANGGYRINPYLINEVTDARGEPLSRAQPLTAGRDAPRTL HHHHCCCHHHHHHCCCCEEEEECCCEEECCEEEECHHCCCCCCCHHCCCCCCCCCCCCCC EPRNAYIMNSLLHSVATAGTGAGTNVLHRSDLQGKTGTTNDAKDGWFAGYQQSLVAVAWM CCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEC GYDQPKSLGSREFGAQLALPIWVEYMQRALRGVPQSEPAQPDGVTSVDGELFYTDMTPGN CCCCCHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCC GFVASIGLDSANPTAGASDAVGGVGPAGMTPPAVPPPSVSSNEKKQIMDLFESNKP CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA