BacMap

Definition	Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession	NC_007951
Length	4,895,836

Click here to switch to the map view.

The map label for this gene is fabG [C]

Identifier: 91783715

GI number: 91783715

Start: 2608888

End: 2609631

Strand: Direct

Name: fabG [C]

Synonym: Bxe_A2099

Alternate gene names: 91783715

Gene position: 2608888-2609631 (Clockwise)

Preceding gene: 91783714

Following gene: 91783718

Centisome position: 53.29

GC content: 65.05

Gene sequence:

>744_bases
ATGCAGAAGAGAGTCGTACTCGTCACCGGCGCCGCGCGTGGTCTGGGCGCCGCGCTTGCCGCGCGCTTTCACGCGGCGGG
CTACGCGGTCGCGATCGGCGATATTGCGTTCGATGCGGCACAAGCCCTTGCGCGCGATCTGAGCGCAGACGGTTCCAGCG
CATTCGCCCTGCATCTCGACGTCACCGCGAAGGCCGCTTTCACTGCTGCGCGCGACGCCATTCTTCAACGCTGGGGCCGT
GTCGACGCGTTGGTCAACAACGCGGGTGCCTCCAAAGTCGTGTCCGTGATGGACATTACGGCGGAGCAGTTCGATCAGGT
CATCAACGTCAATTTGCGGAGCGTGCTGTTCGGCTGCCAGGTGTTCGGCCAGCATTTCGCCGACACGGGCATGGGCCGCA
TCGTCAACATCGCGTCGCTCGCGGGACAGAACGGCGGCTCGGCGACCGGCGCGCATTACGCGGCGGCGAAAGGCGGGGTG
ATTACGCTCACCAAGGTATTCGCGCGCGACCTCGGCGCGGCGGGCGTGACCGTCAACGCCATTTCGCCCGGCCCGATGGA
TCTGCCGATCGTGCATGAAAGCGTGGCGGCCGACAAACTGAAGGCGGTGATCGCGAATATTCCCGCAGGCCGTCTCGGCT
CGGCGGATTATGTCGCCGATGTTGCCGTGATGCTCGCGGCGGAAAATGCTTTCTTCGCGAACGGCGCGTGCTGGGATGTG
AACGGCGGGCTGTTCATGCGCTGA

Upstream 100 bases:

>100_bases
GTGCGCAATCGCGGCACGTTTCGAAGCCGCCCTTGCCGCCTGACGCAGGCATCAAGTCATGCCGCCCGCGCGGCTGGCTG
TTTTATCCGGAGCGCAAGCA

Downstream 100 bases:

>100_bases
CGGCTGAAGCCGGCTCGTGCCACGAGCGGCAGGCGCTCGATGCTGCATGCCGCAGTTGGCCGCAGACTAGCCACCCCGAC
TGCGGGTTATAGGCTTTCTC

Product: putative short-chain dehydrogenase/reductase, TsaC-like

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MQKRVVLVTGAARGLGAALAARFHAAGYAVAIGDIAFDAAQALARDLSADGSSAFALHLDVTAKAAFTAARDAILQRWGR
VDALVNNAGASKVVSVMDITAEQFDQVINVNLRSVLFGCQVFGQHFADTGMGRIVNIASLAGQNGGSATGAHYAAAKGGV
ITLTKVFARDLGAAGVTVNAISPGPMDLPIVHESVAADKLKAVIANIPAGRLGSADYVADVAVMLAAENAFFANGACWDV
NGGLFMR

Sequences:

>Translated_247_residues
MQKRVVLVTGAARGLGAALAARFHAAGYAVAIGDIAFDAAQALARDLSADGSSAFALHLDVTAKAAFTAARDAILQRWGR
VDALVNNAGASKVVSVMDITAEQFDQVINVNLRSVLFGCQVFGQHFADTGMGRIVNIASLAGQNGGSATGAHYAAAKGGV
ITLTKVFARDLGAAGVTVNAISPGPMDLPIVHESVAADKLKAVIANIPAGRLGSADYVADVAVMLAAENAFFANGACWDV
NGGLFMR
>Mature_247_residues
MQKRVVLVTGAARGLGAALAARFHAAGYAVAIGDIAFDAAQALARDLSADGSSAFALHLDVTAKAAFTAARDAILQRWGR
VDALVNNAGASKVVSVMDITAEQFDQVINVNLRSVLFGCQVFGQHFADTGMGRIVNIASLAGQNGGSATGAHYAAAKGGV
ITLTKVFARDLGAAGVTVNAISPGPMDLPIVHESVAADKLKAVIANIPAGRLGSADYVADVAVMLAAENAFFANGACWDV
NGGLFMR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=32.156862745098, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=29.5546558704453, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=28.5123966942149, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=24.21875, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=26.9076305220884, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=31.9230769230769, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=31.2775330396476, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7706318, Length=204, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=190, Percent_Identity=27.8947368421053, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI20149619, Length=204, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=29.064039408867, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI4504505, Length=252, Percent_Identity=28.968253968254, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=30.3846153846154, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=34.8178137651822, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=30.1652892561983, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=30.1204819277108, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=31.5573770491803, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=28.75, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=29.5546558704453, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=29.718875502008, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=30.1158301158301, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=27.3469387755102, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=27.9835390946502, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=29.2817679558011, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=31.5789473684211, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=31.3008130081301, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=27.3092369477912, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=29.0322580645161, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=260, Percent_Identity=34.2307692307692, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=29.0196078431373, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=243, Percent_Identity=28.8065843621399, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=246, Percent_Identity=24.7967479674797, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=29.6153846153846, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=233, Percent_Identity=27.4678111587983, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=240, Percent_Identity=26.25, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=190, Percent_Identity=30, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=250, Percent_Identity=27.2, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=24.0963855421687, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=240, Percent_Identity=27.9166666666667, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=189, Percent_Identity=30.6878306878307, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=26.9709543568465, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=26.7206477732794, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=237, Percent_Identity=27.8481012658228, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=245, Percent_Identity=27.7551020408163, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=244, Percent_Identity=25.8196721311475, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=25.8823529411765, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=157, Percent_Identity=28.0254777070064, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=24.609375, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=238, Percent_Identity=25.6302521008403, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=25.9842519685039, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=240, Percent_Identity=27.5, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=188, Percent_Identity=27.6595744680851, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=243, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=210, Percent_Identity=27.1428571428571, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=210, Percent_Identity=27.1428571428571, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=236, Percent_Identity=23.728813559322, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=29.3193717277487, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=31.9838056680162, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.201581027668, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=31.1740890688259, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=30.6451612903226, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=28.6290322580645, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=31.2741312741313, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=27.4900398406374, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641232, Length=204, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=29.3172690763052, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI116007236, Length=224, Percent_Identity=26.7857142857143, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25198; Mature: 25198

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRVVLVTGAARGLGAALAARFHAAGYAVAIGDIAFDAAQALARDLSADGSSAFALHLD
CCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEE
VTAKAAFTAARDAILQRWGRVDALVNNAGASKVVSVMDITAEQFDQVINVNLRSVLFGCQ
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VFGQHFADTGMGRIVNIASLAGQNGGSATGAHYAAAKGGVITLTKVFARDLGAAGVTVNA
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEHHHHHHHHHCCCCCEEEEE
ISPGPMDLPIVHESVAADKLKAVIANIPAGRLGSADYVADVAVMLAAENAFFANGACWDV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEECCEEEEC
NGGLFMR
CCCEEEC
>Mature Secondary Structure
MQKRVVLVTGAARGLGAALAARFHAAGYAVAIGDIAFDAAQALARDLSADGSSAFALHLD
CCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEE
VTAKAAFTAARDAILQRWGRVDALVNNAGASKVVSVMDITAEQFDQVINVNLRSVLFGCQ
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VFGQHFADTGMGRIVNIASLAGQNGGSATGAHYAAAKGGVITLTKVFARDLGAAGVTVNA
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEHHHHHHHHHCCCCCEEEEE
ISPGPMDLPIVHESVAADKLKAVIANIPAGRLGSADYVADVAVMLAAENAFFANGACWDV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEECCEEEEC
NGGLFMR
CCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]