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The map label for this gene is arcB [H]

Identifier: 91783499

GI number: 91783499

Start: 2348869

End: 2350842

Strand: Direct

Name: arcB [H]

Synonym: Bxe_A2317

Alternate gene names: 91783499

Gene position: 2348869-2350842 (Clockwise)

Preceding gene: 91783498

Following gene: 91783504

Centisome position: 47.98

GC content: 64.89

Gene sequence:

>1974_bases
ATGACCGAAGAAGTGTCCACGCAGCATGCCGCATATGTGCTGGTCGTCGATGACGACGAAGGCATCCTGCGGCTCGCGCG
CAAGTCGCTGGAACGCGCCGGCTGCCGGGTCGCGATCTGCGCGGGCGTCGACGCGGCCCGTGAGCGTCTCGCGCGCGGCG
GCCCCGATTTGCTGGTGCTCGACTATCAGCTCAGCGGGCCCGAGACCGGTCTCGACTTCTTTCGCCATTTGCGCGCTGAA
GGCGTGCGGATTCCCGCCATTCTCGTGACCGGTTTCACCGACGAATCGCGTGTCATCGAAGCGCTGCGCGCGGGCGTGTC
CGACGTGGTGCCGAAATCGGGCGACTACCTCGATTACCTTCCCGAAGCCGTCGAACGGGTGCTCTCGCAAGTGCGTTTGC
AGCGAGCGTCGGACGAGGCCCTGCTGCTGCGCGACCGCGAGCAGCATTACCGCACCTTGTCGGAGGCGTTGCCGCACCTC
GTCATGACCTGCAACGCCGCGGGCGACTGCGATTTTCTGTCGAAGCAGTGGTACGACTACACCGGCCTTGCCGAAGGCAG
TTCGTATGGTCTCGCCTGGCTCGACGCCGTGCATCCGGACGACCGCGAAGTGATCCGCCGCAGCTGGCTCAAGGCCGTGT
CGGGCAATGCCGGCGACTACCGGCACGAGTTGCGGATTCGCCGCCACGACGGCGAATACCGCTGGTTCGACGTCCGCGTG
GTGGCGATGCGCGACGCCGAAGGCAACATCAGCAAATGGTTCGGCAGTTGCACCGACATTCATTCGCAACGCGAGGCGAT
CGAGGAGCGCGAACGTCTGCTTGCGTCGGAACAGGCCGCGCGCCAGATCGCCGAAGAAGCGAATCGCGCCAAAGACCGCT
TTCTGGCCATGCTGTCGCACGAACTGCGTACGCCGCTCACGCCGGTGCTCGCCGGCGCCAGCGTGCTGGAGATGATTCCG
GAACTGCCCGACCAGGCGCGCGCGAGCGTGCGCATGATTCGCCGTAACGTCGAACTCGAGGCGCGGCTGATCGACGACCT
GCTCGACCTGACGCGGGTGGCGAACGGCAAGCTGCGGCTCTCGCTGGAAACTGTCGACGTGCACGACGTGATGGACAGCG
TGCTCGAACTGTTTCGCAGCGAGATTCAGGTCAAGCAGCAGGACGTGCACGTTCATAAGAACGCCCGGCATCATTACGTG
CTGGCCGATCGCGCCCGGCTGCAGCAGATGCTGTGGAACCTGATTCGCAATGCCGCGAAGTTCACCCCGGACGGCGGCCA
TATCTATGTGCGCACCCGCGACGAACGCATGCACGTGCAGATAGCGGTCGAAGATACGGGCATCGGCATCGAGCCGGACC
AGATCGGCAAACTCTTCAACGCGTTCGAGCAGGGCAACCAGAACATGACGCGGCAATTCGGCGGGCTCGGTCTCGGGCTC
GCCATCACGAAGGCGTTGACCGACGTGCATGGCGGCACGGTGACTGCGCAAAGCCCCGGCGCGCATTGCGGCGCGACCTT
CACGATCACCTTGCCGACGGCCACGGCGCCGGAAGTCACGTCACCTGTCGTAGTGCCGGACCAGGTGCATCCGGCCGGTC
TGCTGACCATCCTGCTGATCGAAGATCACGTGGATACCGCTGAAGTCATGGCGCAACTGATTCGCAGCCTCGGCCACGAG
GTGACGACCGTGGGCCGGGTGGACGACGCGCTGGCCGCCACCCAATCGGCGGACTTCGATCTGGTGATCAGCGACGTGGG
TCTGCCCGACGGCACCGGCCTCGACTTCATCAAGGTGTTCCGCGAGCACTCGGACGCGCCCGCGGTGGCATTGACCGGCT
TCGGCACCGACGAAGACGTGCGCCGCTGCCTCAGCGCCGGCTTTACTTCGCATCTGACCAAGCCAGTCAACTTCGGCCAG
CTCGAGACAATGATCGAAGGCGCGGTGAACCGCAAGGAGCAGAAGGAGGCTTGA

Upstream 100 bases:

>100_bases
ATCGTTTTTCGGGCCCGTGATGGAAGGCCGCATGAAGGTGGCCGAAAGCCGCTCGTGACAAGATGGACCACTTGCCGACC
CTAGCCAGAGAAGACTTCGC

Downstream 100 bases:

>100_bases
GCGATTGCGCTGCCGGTATCGGCTCACGCTATGAATAAGGCCTGTTGCGAGCGGATCGCAACAGGCCTTTTGCTTTACCG
GCGGCTGACGTGCCGGAATG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 656

Protein sequence:

>657_residues
MTEEVSTQHAAYVLVVDDDEGILRLARKSLERAGCRVAICAGVDAARERLARGGPDLLVLDYQLSGPETGLDFFRHLRAE
GVRIPAILVTGFTDESRVIEALRAGVSDVVPKSGDYLDYLPEAVERVLSQVRLQRASDEALLLRDREQHYRTLSEALPHL
VMTCNAAGDCDFLSKQWYDYTGLAEGSSYGLAWLDAVHPDDREVIRRSWLKAVSGNAGDYRHELRIRRHDGEYRWFDVRV
VAMRDAEGNISKWFGSCTDIHSQREAIEERERLLASEQAARQIAEEANRAKDRFLAMLSHELRTPLTPVLAGASVLEMIP
ELPDQARASVRMIRRNVELEARLIDDLLDLTRVANGKLRLSLETVDVHDVMDSVLELFRSEIQVKQQDVHVHKNARHHYV
LADRARLQQMLWNLIRNAAKFTPDGGHIYVRTRDERMHVQIAVEDTGIGIEPDQIGKLFNAFEQGNQNMTRQFGGLGLGL
AITKALTDVHGGTVTAQSPGAHCGATFTITLPTATAPEVTSPVVVPDQVHPAGLLTILLIEDHVDTAEVMAQLIRSLGHE
VTTVGRVDDALAATQSADFDLVISDVGLPDGTGLDFIKVFREHSDAPAVALTGFGTDEDVRRCLSAGFTSHLTKPVNFGQ
LETMIEGAVNRKEQKEA

Sequences:

>Translated_657_residues
MTEEVSTQHAAYVLVVDDDEGILRLARKSLERAGCRVAICAGVDAARERLARGGPDLLVLDYQLSGPETGLDFFRHLRAE
GVRIPAILVTGFTDESRVIEALRAGVSDVVPKSGDYLDYLPEAVERVLSQVRLQRASDEALLLRDREQHYRTLSEALPHL
VMTCNAAGDCDFLSKQWYDYTGLAEGSSYGLAWLDAVHPDDREVIRRSWLKAVSGNAGDYRHELRIRRHDGEYRWFDVRV
VAMRDAEGNISKWFGSCTDIHSQREAIEERERLLASEQAARQIAEEANRAKDRFLAMLSHELRTPLTPVLAGASVLEMIP
ELPDQARASVRMIRRNVELEARLIDDLLDLTRVANGKLRLSLETVDVHDVMDSVLELFRSEIQVKQQDVHVHKNARHHYV
LADRARLQQMLWNLIRNAAKFTPDGGHIYVRTRDERMHVQIAVEDTGIGIEPDQIGKLFNAFEQGNQNMTRQFGGLGLGL
AITKALTDVHGGTVTAQSPGAHCGATFTITLPTATAPEVTSPVVVPDQVHPAGLLTILLIEDHVDTAEVMAQLIRSLGHE
VTTVGRVDDALAATQSADFDLVISDVGLPDGTGLDFIKVFREHSDAPAVALTGFGTDEDVRRCLSAGFTSHLTKPVNFGQ
LETMIEGAVNRKEQKEA
>Mature_656_residues
TEEVSTQHAAYVLVVDDDEGILRLARKSLERAGCRVAICAGVDAARERLARGGPDLLVLDYQLSGPETGLDFFRHLRAEG
VRIPAILVTGFTDESRVIEALRAGVSDVVPKSGDYLDYLPEAVERVLSQVRLQRASDEALLLRDREQHYRTLSEALPHLV
MTCNAAGDCDFLSKQWYDYTGLAEGSSYGLAWLDAVHPDDREVIRRSWLKAVSGNAGDYRHELRIRRHDGEYRWFDVRVV
AMRDAEGNISKWFGSCTDIHSQREAIEERERLLASEQAARQIAEEANRAKDRFLAMLSHELRTPLTPVLAGASVLEMIPE
LPDQARASVRMIRRNVELEARLIDDLLDLTRVANGKLRLSLETVDVHDVMDSVLELFRSEIQVKQQDVHVHKNARHHYVL
ADRARLQQMLWNLIRNAAKFTPDGGHIYVRTRDERMHVQIAVEDTGIGIEPDQIGKLFNAFEQGNQNMTRQFGGLGLGLA
ITKALTDVHGGTVTAQSPGAHCGATFTITLPTATAPEVTSPVVVPDQVHPAGLLTILLIEDHVDTAEVMAQLIRSLGHEV
TTVGRVDDALAATQSADFDLVISDVGLPDGTGLDFIKVFREHSDAPAVALTGFGTDEDVRRCLSAGFTSHLTKPVNFGQL
ETMIEGAVNRKEQKEA

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=543, Percent_Identity=27.0718232044199, Blast_Score=159, Evalue=7e-40,
Organism=Escherichia coli, GI87081816, Length=387, Percent_Identity=31.5245478036176, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788713, Length=395, Percent_Identity=26.8354430379747, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1786912, Length=254, Percent_Identity=33.8582677165354, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=34.5381526104418, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=32.258064516129, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=32.7433628318584, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786783, Length=248, Percent_Identity=28.6290322580645, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=29.3617021276596, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=26.3598326359833, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788279, Length=223, Percent_Identity=30.4932735426009, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=28.7610619469027, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=28.5087719298246, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790551, Length=214, Percent_Identity=28.9719626168224, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=265, Percent_Identity=28.6792452830189, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=27.710843373494, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=25.5506607929515, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789808, Length=219, Percent_Identity=27.8538812785388, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=82, Percent_Identity=41.4634146341463, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72793; Mature: 72662

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEVSTQHAAYVLVVDDDEGILRLARKSLERAGCRVAICAGVDAARERLARGGPDLLVL
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEE
DYQLSGPETGLDFFRHLRAEGVRIPAILVTGFTDESRVIEALRAGVSDVVPKSGDYLDYL
EEECCCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCHHHCCCCCCCHHHHH
PEAVERVLSQVRLQRASDEALLLRDREQHYRTLSEALPHLVMTCNAAGDCDFLSKQWYDY
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHCCCC
TGLAEGSSYGLAWLDAVHPDDREVIRRSWLKAVSGNAGDYRHELRIRRHDGEYRWFDVRV
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCEEEEEEEE
VAMRDAEGNISKWFGSCTDIHSQREAIEERERLLASEQAARQIAEEANRAKDRFLAMLSH
EEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRTPLTPVLAGASVLEMIPELPDQARASVRMIRRNVELEARLIDDLLDLTRVANGKLRL
HHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEE
SLETVDVHDVMDSVLELFRSEIQVKQQDVHVHKNARHHYVLADRARLQQMLWNLIRNAAK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
FTPDGGHIYVRTRDERMHVQIAVEDTGIGIEPDQIGKLFNAFEQGNQNMTRQFGGLGLGL
CCCCCCEEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
AITKALTDVHGGTVTAQSPGAHCGATFTITLPTATAPEVTSPVVVPDQVHPAGLLTILLI
HHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEE
EDHVDTAEVMAQLIRSLGHEVTTVGRVDDALAATQSADFDLVISDVGLPDGTGLDFIKVF
ECCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHH
REHSDAPAVALTGFGTDEDVRRCLSAGFTSHLTKPVNFGQLETMIEGAVNRKEQKEA
HHCCCCCEEEEECCCCCHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
TEEVSTQHAAYVLVVDDDEGILRLARKSLERAGCRVAICAGVDAARERLARGGPDLLVL
CCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEE
DYQLSGPETGLDFFRHLRAEGVRIPAILVTGFTDESRVIEALRAGVSDVVPKSGDYLDYL
EEECCCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCHHHCCCCCCCHHHHH
PEAVERVLSQVRLQRASDEALLLRDREQHYRTLSEALPHLVMTCNAAGDCDFLSKQWYDY
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHCCCC
TGLAEGSSYGLAWLDAVHPDDREVIRRSWLKAVSGNAGDYRHELRIRRHDGEYRWFDVRV
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEECCCEEEEEEEE
VAMRDAEGNISKWFGSCTDIHSQREAIEERERLLASEQAARQIAEEANRAKDRFLAMLSH
EEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRTPLTPVLAGASVLEMIPELPDQARASVRMIRRNVELEARLIDDLLDLTRVANGKLRL
HHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEE
SLETVDVHDVMDSVLELFRSEIQVKQQDVHVHKNARHHYVLADRARLQQMLWNLIRNAAK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
FTPDGGHIYVRTRDERMHVQIAVEDTGIGIEPDQIGKLFNAFEQGNQNMTRQFGGLGLGL
CCCCCCEEEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
AITKALTDVHGGTVTAQSPGAHCGATFTITLPTATAPEVTSPVVVPDQVHPAGLLTILLI
HHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEE
EDHVDTAEVMAQLIRSLGHEVTTVGRVDDALAATQSADFDLVISDVGLPDGTGLDFIKVF
ECCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHH
REHSDAPAVALTGFGTDEDVRRCLSAGFTSHLTKPVNFGQLETMIEGAVNRKEQKEA
HHCCCCCEEEEECCCCCHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]