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The map label for this gene is tpm [H]

Identifier: 91781799

GI number: 91781799

Start: 462084

End: 462707

Strand: Direct

Name: tpm [H]

Synonym: Bxe_A4046

Alternate gene names: 91781799

Gene position: 462084-462707 (Clockwise)

Preceding gene: 91781798

Following gene: 91781800

Centisome position: 9.44

GC content: 67.79

Gene sequence:

>624_bases
ATGAGCGATCCGACCCAACCCGCCGTGCCCGACTTCGAAACGCGCGATCCCAACTCACCCGCTTTCTGGGACGAGCGTTT
CGAGCGCCGTTTCACGCCTTGGGATCAGGCTGGCGTGCCGGCCGCGTTTCAGTCGTTCGCCGCCCGCCACAGCGGCGCGG
CCGTACTGATTCCGGGCTGCGGCAGTGCCTACGAAGCGGTGTGGCTGGCCGGACAGGGCAACCCGGTCCGGGCCATCGAC
TTTTCACCGGCCGCCGTCGCGGCGGCGCATGAGCAACTGGGTGCGCAGCACGCGCAACTGGTGGAACAGGCGGACTTCTT
CACCTATGAACCGCCGTTCACGCCCGCGTGGATTTACGAGCGCGCATTCCTCTGCGCGCTGCCGCTCGCCCGCCGCGCGG
ACTATGCGCACCGGATGGCGGATCTGTTGCCCGGCGGCGCGTTGCTCGCGGGCTTCTTTTTCCTTGGCGCGACGCCGAAA
GGGCCGCCGTTCGGCATCGAGCGCGCGGAGCTCGATGCGCTGCTCACGCCGTACTTCGACTTGATCGAAGACGAAGCCGT
GCACGATTCGATTGCCGTTTTCGCGGGACGTGAGCGCTGGCTAACCTGGCGCCGCCGCGCCTGA

Upstream 100 bases:

>100_bases
TGCTGCTGTTCGGTGTGGCGGTGGGTGTCGGCGCGGCGCTGGCGCGGGTGTTTCTGGCGCTCGCTTACGGCGGCTGAATG
CAATCCCCAGGAGGCACTTG

Downstream 100 bases:

>100_bases
ACGCGCGGCTGTGGCGCGTCACGGCCGCGCGGACCGGACTTGATTCGACAGCGGCCGCCCCCACTTGAATGGACGGCGGC
TGCGTCGGGCGCTCGTCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: Thiopurine methyltransferase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSDPTQPAVPDFETRDPNSPAFWDERFERRFTPWDQAGVPAAFQSFAARHSGAAVLIPGCGSAYEAVWLAGQGNPVRAID
FSPAAVAAAHEQLGAQHAQLVEQADFFTYEPPFTPAWIYERAFLCALPLARRADYAHRMADLLPGGALLAGFFFLGATPK
GPPFGIERAELDALLTPYFDLIEDEAVHDSIAVFAGRERWLTWRRRA

Sequences:

>Translated_207_residues
MSDPTQPAVPDFETRDPNSPAFWDERFERRFTPWDQAGVPAAFQSFAARHSGAAVLIPGCGSAYEAVWLAGQGNPVRAID
FSPAAVAAAHEQLGAQHAQLVEQADFFTYEPPFTPAWIYERAFLCALPLARRADYAHRMADLLPGGALLAGFFFLGATPK
GPPFGIERAELDALLTPYFDLIEDEAVHDSIAVFAGRERWLTWRRRA
>Mature_206_residues
SDPTQPAVPDFETRDPNSPAFWDERFERRFTPWDQAGVPAAFQSFAARHSGAAVLIPGCGSAYEAVWLAGQGNPVRAIDF
SPAAVAAAHEQLGAQHAQLVEQADFFTYEPPFTPAWIYERAFLCALPLARRADYAHRMADLLPGGALLAGFFFLGATPKG
PPFGIERAELDALLTPYFDLIEDEAVHDSIAVFAGRERWLTWRRRA

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TPMT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022474
- InterPro:   IPR008854
- InterPro:   IPR016822 [H]

Pfam domain/function: PF05724 TPMT [H]

EC number: =2.1.1.67 [H]

Molecular weight: Translated: 22850; Mature: 22719

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPTQPAVPDFETRDPNSPAFWDERFERRFTPWDQAGVPAAFQSFAARHSGAAVLIPGC
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEECCC
GSAYEAVWLAGQGNPVRAIDFSPAAVAAAHEQLGAQHAQLVEQADFFTYEPPFTPAWIYE
CCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHH
RAFLCALPLARRADYAHRMADLLPGGALLAGFFFLGATPKGPPFGIERAELDALLTPYFD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LIEDEAVHDSIAVFAGRERWLTWRRRA
HHHHHHHHHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure 
SDPTQPAVPDFETRDPNSPAFWDERFERRFTPWDQAGVPAAFQSFAARHSGAAVLIPGC
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEECCC
GSAYEAVWLAGQGNPVRAIDFSPAAVAAAHEQLGAQHAQLVEQADFFTYEPPFTPAWIYE
CCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHH
RAFLCALPLARRADYAHRMADLLPGGALLAGFFFLGATPKGPPFGIERAELDALLTPYFD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LIEDEAVHDSIAVFAGRERWLTWRRRA
HHHHHHHHHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA