Click here to switch to the map view.

The map label for this gene is ubiB [H]

Identifier: 91781798

GI number: 91781798

Start: 460483

End: 462060

Strand: Direct

Name: ubiB [H]

Synonym: Bxe_A4047

Alternate gene names: 91781798

Gene position: 460483-462060 (Clockwise)

Preceding gene: 91781797

Following gene: 91781799

Centisome position: 9.41

GC content: 63.62

Gene sequence:

>1578_bases
ATGCGTTTTCTGCGTTTCCTCAAGATTTTTTTCACGGTCATCCGCTTCGGTCTCGATGAGATGATGCTCAGCCGCGTCAA
CGACCGGCGCGTGCGTCTGCTGTTGCGCATCACCACCATCGGCCGCAAGTTCGACGCGCCGCCGGGCGTACGTTTGCGGC
TCGCGCTGGAAAGCCTCGGGCCGATCTTCGTCAAGTTCGGGCAGGTGTTGTCCACCCGGCGCGATCTGTTGCCGGTGGAT
ATCGCCAACGAACTGGCGAAACTCCAGGATCAGGTGCCGCCGTTCGATTCGGCGGTGGCGATCGGGCTGGTCGAGAAGTC
GCTCGGCGCGCCGGTCGACGTGCTGTTCGACGATTTCGAGCGGGTGCCGGTGGCGAGCGCCTCGATCGCGCAGGTGCACT
TCGCCACGGTGAAGGCGGGGCAACACGCGGGCAAGGCCGTCGCCGTGAAGGTGCTGCGGCCGAACATGCTGCCGGTGATC
GATTCCGACCTTGCCCTGCTGCGCGACATCGCCGTGTGGGCGGAGCGGCTGTGGGCCGACGGCAAGCGTCTGAAGCCGCG
CGAGGTGGTCGCCGAATTCGACAAATACCTGCACGACGAACTCGACCTGATGCGTGAGGCAGCCAACGGCAGCCAGTTGC
GGCGCAACTTTGCCGGACTCGATCTGCTGCTGGTGCCGGAGATGTACTGGGAGTTCTGCACACCCACGGTGCTGGTGATG
GAGCGCATGGTCGGCGTGCCGATCAGCCAGGTGGAGACGCTGCGCGCGGCGGGCGTGGATATTCCGAAGCTGGCGCGCGA
AGGCGTCGAGATTTTCTTTACCCAGGTGTTCCGCGACGGCTTTTTCCATGCCGACATGCATCCGGGCAACATTCAGGTGA
GCCTCGATCCGGCGCATTTCGGCCGCTATATCGCACTCGACTTCGGCATCATCGGCGCGCTGTCGGACTTCGACAAGAAC
TACCTCGCGCAGAACTTCCTTGCGTTCTTCAAGCGCGACTACCATCGGGTCGCAACGCTGCATCTGGAGTCGGGCTGGGT
GCCGCCGACTACCCGCGTCGAAGAACTCGAAAGCGCGATCCGCGCGGTCTGCGAACCGTACTTCGACCGCGCGCTGAAAG
ATATTTCGCTGGGCCAGGTCCTGATGCGCCTGTTCTCGACCTCGCGCCGCTTCAACGTCGAGATCCAGCCGCAACTGGTG
CTGCTGCAAAAGACCATGCTGAATGTAGAAGGTCTCGGCCGCTCGCTCGATCCCGAACTGGATCTGTGGAAGACCGCCAA
GCCGTACCTCGAACGCTGGATGAACGAACAGATCGGCCTGCGCGGCTGGTACGAGCGCCTGAAGATCGAGGCGCCACAAT
GGAGCAAGACGCTGCCGCAACTGCCGCGCCTGATCCATCACGCGCTGGCCGAGCGCCACGACCACACGCGCGGCGCGAAC
GACGAAATGATTCGCCAGATTCTGCTCGAGCAGAAACGCACCAACCGGTTGTTGCAAGGCCTGCTGCTGTTCGGTGTGGC
GGTGGGTGTCGGCGCGGCGCTGGCGCGGGTGTTTCTGGCGCTCGCTTACGGCGGCTGA

Upstream 100 bases:

>100_bases
ACGCATCGAGCGTCTTGAACAGAAGGTCGAAGCCCGCGGCGCCCAAGCGCCGGGCGGCGCCGCCATGTCGCGCGGCACGC
GCTAGTCACCGGGCACAACT

Downstream 100 bases:

>100_bases
ATGCAATCCCCAGGAGGCACTTGATGAGCGATCCGACCCAACCCGCCGTGCCCGACTTCGAAACGCGCGATCCCAACTCA
CCCGCTTTCTGGGACGAGCG

Product: putative ubiquinone biosynthesis protein UbiB

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MRFLRFLKIFFTVIRFGLDEMMLSRVNDRRVRLLLRITTIGRKFDAPPGVRLRLALESLGPIFVKFGQVLSTRRDLLPVD
IANELAKLQDQVPPFDSAVAIGLVEKSLGAPVDVLFDDFERVPVASASIAQVHFATVKAGQHAGKAVAVKVLRPNMLPVI
DSDLALLRDIAVWAERLWADGKRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMYWEFCTPTVLVM
ERMVGVPISQVETLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPAHFGRYIALDFGIIGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPTTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMNEQIGLRGWYERLKIEAPQWSKTLPQLPRLIHHALAERHDHTRGAN
DEMIRQILLEQKRTNRLLQGLLLFGVAVGVGAALARVFLALAYGG

Sequences:

>Translated_525_residues
MRFLRFLKIFFTVIRFGLDEMMLSRVNDRRVRLLLRITTIGRKFDAPPGVRLRLALESLGPIFVKFGQVLSTRRDLLPVD
IANELAKLQDQVPPFDSAVAIGLVEKSLGAPVDVLFDDFERVPVASASIAQVHFATVKAGQHAGKAVAVKVLRPNMLPVI
DSDLALLRDIAVWAERLWADGKRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMYWEFCTPTVLVM
ERMVGVPISQVETLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPAHFGRYIALDFGIIGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPTTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMNEQIGLRGWYERLKIEAPQWSKTLPQLPRLIHHALAERHDHTRGAN
DEMIRQILLEQKRTNRLLQGLLLFGVAVGVGAALARVFLALAYGG
>Mature_525_residues
MRFLRFLKIFFTVIRFGLDEMMLSRVNDRRVRLLLRITTIGRKFDAPPGVRLRLALESLGPIFVKFGQVLSTRRDLLPVD
IANELAKLQDQVPPFDSAVAIGLVEKSLGAPVDVLFDDFERVPVASASIAQVHFATVKAGQHAGKAVAVKVLRPNMLPVI
DSDLALLRDIAVWAERLWADGKRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMYWEFCTPTVLVM
ERMVGVPISQVETLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPAHFGRYIALDFGIIGALSDFDKN
YLAQNFLAFFKRDYHRVATLHLESGWVPPTTRVEELESAIRAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLV
LLQKTMLNVEGLGRSLDPELDLWKTAKPYLERWMNEQIGLRGWYERLKIEAPQWSKTLPQLPRLIHHALAERHDHTRGAN
DEMIRQILLEQKRTNRLLQGLLLFGVAVGVGAALARVFLALAYGG

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=262, Percent_Identity=29.3893129770992, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI41393593, Length=276, Percent_Identity=29.3478260869565, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI32261307, Length=388, Percent_Identity=28.3505154639175, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI217035081, Length=216, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI34147522, Length=195, Percent_Identity=31.2820512820513, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI2367309, Length=525, Percent_Identity=49.1428571428571, Blast_Score=499, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17559152, Length=280, Percent_Identity=29.2857142857143, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6325148, Length=451, Percent_Identity=25.2771618625277, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323282, Length=255, Percent_Identity=27.0588235294118, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321319, Length=217, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI22024280, Length=272, Percent_Identity=29.0441176470588, Blast_Score=122, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24662575, Length=260, Percent_Identity=30.3846153846154, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 59591; Mature: 59591

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLRFLKIFFTVIRFGLDEMMLSRVNDRRVRLLLRITTIGRKFDAPPGVRLRLALESLG
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHC
PIFVKFGQVLSTRRDLLPVDIANELAKLQDQVPPFDSAVAIGLVEKSLGAPVDVLFDDFE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
RVPVASASIAQVHFATVKAGQHAGKAVAVKVLRPNMLPVIDSDLALLRDIAVWAERLWAD
HCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC
GKRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMYWEFCTPTVLVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECHHHHHHHHCHHHHHH
ERMVGVPISQVETLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPAHF
HHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEECHHHH
GRYIALDFGIIGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPTTRVEELESAI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
RAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPEL
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
DLWKTAKPYLERWMNEQIGLRGWYERLKIEAPQWSKTLPQLPRLIHHALAERHDHTRGAN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
DEMIRQILLEQKRTNRLLQGLLLFGVAVGVGAALARVFLALAYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFLRFLKIFFTVIRFGLDEMMLSRVNDRRVRLLLRITTIGRKFDAPPGVRLRLALESLG
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHC
PIFVKFGQVLSTRRDLLPVDIANELAKLQDQVPPFDSAVAIGLVEKSLGAPVDVLFDDFE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
RVPVASASIAQVHFATVKAGQHAGKAVAVKVLRPNMLPVIDSDLALLRDIAVWAERLWAD
HCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC
GKRLKPREVVAEFDKYLHDELDLMREAANGSQLRRNFAGLDLLLVPEMYWEFCTPTVLVM
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECHHHHHHHHCHHHHHH
ERMVGVPISQVETLRAAGVDIPKLAREGVEIFFTQVFRDGFFHADMHPGNIQVSLDPAHF
HHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEECHHHH
GRYIALDFGIIGALSDFDKNYLAQNFLAFFKRDYHRVATLHLESGWVPPTTRVEELESAI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH
RAVCEPYFDRALKDISLGQVLMRLFSTSRRFNVEIQPQLVLLQKTMLNVEGLGRSLDPEL
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCC
DLWKTAKPYLERWMNEQIGLRGWYERLKIEAPQWSKTLPQLPRLIHHALAERHDHTRGAN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
DEMIRQILLEQKRTNRLLQGLLLFGVAVGVGAALARVFLALAYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA