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The map label for this gene is rutG [H]

Identifier: 91781551

GI number: 91781551

Start: 194080

End: 195387

Strand: Direct

Name: rutG [H]

Synonym: Bxe_A4294

Alternate gene names: 91781551

Gene position: 194080-195387 (Clockwise)

Preceding gene: 91781548

Following gene: 91781553

Centisome position: 3.96

GC content: 64.68

Gene sequence:

>1308_bases
ATGGCCGATTCGTATTTCCCCCGCTGGCGCGCGCAGCCCGCGGCTGCCGAAGGCCGCATCGTCGGCACCGACGAGCGGCT
CGCGTGGCCGCAGATGTTCGCGATGGGCGTGCAACACGTCGTCGCGATGTTCGGCTCGACGGTGCTCGCGCCGTTGCTGA
TGGGCTTCGATCCGAACCTGTGCATCTTCATGTCGGGCATCGGCACACTGTTGTTCTTCGTGCTGGTGGGCGGGCGCGTG
CCGAGCTATCTCGGTTCGAGCTTCGCGTTCATCGGTCTCGTGATCGCGGTGACTGGGTACGGCGGCCACGGTCCGAACCT
GAACATTCCGGTGGCGCTGGGCGGGATCATCGCGTGCGGCGTGGTGTATGCGGTGATCGGCCTGATCGTGTCGGCGGTCG
GCACGCGATGGATCGAAACGCTGATGCCGCCCGTCGTGACAGGCGCGATTGTCTGCGTGATCGGTCTGAATCTGGCGCCG
ATCGCGGTGCATGGCGTGAGCGGCAGCAACTTCGATTCGTGGATGGCGCTCGTCACCGTGCTGTGCGTCGGCGCGGTGGC
GGTGTTCGCGCGCGGCATGCTGCAGCGTCTGCTGATTCTGGTCGGCCTGCTGATGGCATATGTGATCTATGCGATCGTCA
CCAACGGTCTCGGCATGGGTAAGCCGATCGATTTCACGATCGTCGCGAACGCAGCGTGGTTCGGTATGCCGCACTTCACG
GCGCCGGTTTTCAACATGCAGGCCATGACCCTGCTCGCGCCGATCGCGGTGATTCTGGTGGCGGAGAACCTCGGGCATAT
CAAGGCGGTGAGCGCGATGACGGGCCAGAACCTGGACCGCTACGTCGGCCGCGCATTTCTCGGCGACGGACTCGCGACGA
TCGTCTCGGGCTTCGCCGGCGGCACCGGCGTCACGACGTATGCCGAGAACATCGGCGTGATGGCCGTCACCAAAATCTAT
TCGACGCTGGTTTTCGTGATCGCCGCAGTGATCGCGCTGGTGCTGGGCTTTTCGCCGAAGTTCGGCGCGGTGATCCAGAC
CATTCCGGGACCGGTGCTGGGCGGCGTGTCGATCGTCGTGTTCGGGCTGATCGCCGTGACCGGCGCGCGGATCTGGGTCG
TCAACAAGGTGGACTTCTCGGACAACCGGAATCTGATCGTGGCCGCGGTCACGCTCGTGCTCGGCGCCGGTGATTTCTCG
CTGAAGCTCGGCGGCTTCGGTCTGGGCGGCATCGGTACCGCAACGTTCGGCGCGATCATTCTCTATGCGCTGCTGAGAAG
GAAGCCGGTGCAAGGTCCGGTGGCCTGA

Upstream 100 bases:

>100_bases
CAGGCCCAATGGCACTCCGTACACTCGCGCGTAATTCATGGGCGGCGCCTTGTTCCGGCGCGGCCCACCATAAAAACGCC
GAACAGAGGAGAACCCCGTC

Downstream 100 bases:

>100_bases
TTTTTTCTCTCCGGTATCAGCGGGTTCACCGGCGGCGTCGGCCTCTTCTTTCGTGATGTCTCATTCGAAGCAGCAGGCGC
CCGCCGCCGGAACCGCAACC

Product: nucleobase/cation symporter, (NCS2) family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MADSYFPRWRAQPAAAEGRIVGTDERLAWPQMFAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAVTGYGGHGPNLNIPVALGGIIACGVVYAVIGLIVSAVGTRWIETLMPPVVTGAIVCVIGLNLAP
IAVHGVSGSNFDSWMALVTVLCVGAVAVFARGMLQRLLILVGLLMAYVIYAIVTNGLGMGKPIDFTIVANAAWFGMPHFT
APVFNMQAMTLLAPIAVILVAENLGHIKAVSAMTGQNLDRYVGRAFLGDGLATIVSGFAGGTGVTTYAENIGVMAVTKIY
STLVFVIAAVIALVLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFS
LKLGGFGLGGIGTATFGAIILYALLRRKPVQGPVA

Sequences:

>Translated_435_residues
MADSYFPRWRAQPAAAEGRIVGTDERLAWPQMFAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAVTGYGGHGPNLNIPVALGGIIACGVVYAVIGLIVSAVGTRWIETLMPPVVTGAIVCVIGLNLAP
IAVHGVSGSNFDSWMALVTVLCVGAVAVFARGMLQRLLILVGLLMAYVIYAIVTNGLGMGKPIDFTIVANAAWFGMPHFT
APVFNMQAMTLLAPIAVILVAENLGHIKAVSAMTGQNLDRYVGRAFLGDGLATIVSGFAGGTGVTTYAENIGVMAVTKIY
STLVFVIAAVIALVLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFS
LKLGGFGLGGIGTATFGAIILYALLRRKPVQGPVA
>Mature_434_residues
ADSYFPRWRAQPAAAEGRIVGTDERLAWPQMFAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRVP
SYLGSSFAFIGLVIAVTGYGGHGPNLNIPVALGGIIACGVVYAVIGLIVSAVGTRWIETLMPPVVTGAIVCVIGLNLAPI
AVHGVSGSNFDSWMALVTVLCVGAVAVFARGMLQRLLILVGLLMAYVIYAIVTNGLGMGKPIDFTIVANAAWFGMPHFTA
PVFNMQAMTLLAPIAVILVAENLGHIKAVSAMTGQNLDRYVGRAFLGDGLATIVSGFAGGTGVTTYAENIGVMAVTKIYS
TLVFVIAAVIALVLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFSL
KLGGFGLGGIGTATFGAIILYALLRRKPVQGPVA

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680143, Length=139, Percent_Identity=32.3741007194245, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI44680145, Length=139, Percent_Identity=32.3741007194245, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081818, Length=433, Percent_Identity=70.9006928406467, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1788843, Length=407, Percent_Identity=38.0835380835381, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI87082181, Length=454, Percent_Identity=24.6696035242291, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790087, Length=446, Percent_Identity=24.4394618834081, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082178, Length=414, Percent_Identity=24.8792270531401, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17558856, Length=181, Percent_Identity=30.3867403314917, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17542262, Length=176, Percent_Identity=30.1136363636364, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17541904, Length=209, Percent_Identity=27.7511961722488, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=179, Percent_Identity=31.2849162011173, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17542260, Length=181, Percent_Identity=30.3867403314917, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356175, Length=176, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45030; Mature: 44899

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCC
>Mature Secondary Structure 
ADSYFPRWRAQPAAAEGRIVGTDERLAWPQMFAMGVQHVVAMFGSTVLAPLLMGFDPNL
CCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
CIFMSGIGTLLFFVLVGGRVPSYLGSSFAFIGLVIAVTGYGGHGPNLNIPVALGGIIACG
HHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
VVYAVIGLIVSAVGTRWIETLMPPVVTGAIVCVIGLNLAPIAVHGVSGSNFDSWMALVTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHH
LCVGAVAVFARGMLQRLLILVGLLMAYVIYAIVTNGLGMGKPIDFTIVANAAWFGMPHFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHCCCCCC
APVFNMQAMTLLAPIAVILVAENLGHIKAVSAMTGQNLDRYVGRAFLGDGLATIVSGFAG
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHCCC
GTGVTTYAENIGVMAVTKIYSTLVFVIAAVIALVLGFSPKFGAVIQTIPGPVLGGVSIVV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHH
FGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFSLKLGGFGLGGIGTATFGAII
HHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
LYALLRRKPVQGPVA
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]