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The map label for this gene is cph2 [H]

Identifier: 91781548

GI number: 91781548

Start: 191016

End: 192584

Strand: Direct

Name: cph2 [H]

Synonym: Bxe_A4297

Alternate gene names: 91781548

Gene position: 191016-192584 (Clockwise)

Preceding gene: 91781547

Following gene: 91781551

Centisome position: 3.9

GC content: 65.33

Gene sequence:

>1569_bases
ATGCCCGAACGACAAGTCATGGTGACGCGCCGACCGAACATCGTGATTGCGATCAGTATCGTGCTGGCCAGCGCGATACT
TGCAATCGCCGTGTGGGTGCTGGCGCAGATGCGCGACGACGCGTTGCGGCGCGCCCAGGACTCCGTCTTCAACGTGTCGC
TGCTGGTCGAACGCGACGTGTCGCGTAATCTGGAGATCTACGACCTTTCTTTGCGCGCGGTGCTCGACGGCCTGAAGCAG
CCGGGCGTGCTCGACCTGAAGCCGGCTATGCGCCAGATGGTGCTGTTCGACGGCTCGGCCAGCGCGAAAGACATGGGCTC
GATCCTCGTGACCGACGAGGCCGGCAACGTCAGGTTCGACTCACAGGCCACCCCGCCGCGCCAGGTGAATCTCGCCGACC
GCGATTACTTCAAGGTTCAGCGCGACTCTCCCAACGCCGGTCTGTTCATCAGCCACCCGTTCATCCCGAAAGTGGGCGGC
AAAGACGTGAGCATCGCGCTGAGCCGGCGGATCACGCGGCCGGACGGCGGTTTCGGCGGCGTGGTGGCCGGCACCATGCG
CCTTACCTATTTCCACAGTCTGTTCGCCGGCATGAATCTCGGCGTTGGCGGCTCGATGGCGCTGATGCTGAGCGACGGCA
CGATGCTGATGCGGCGTCCGTACGACCCGAAAATGATCGGCATCAATCTGACCGGCACCGCCAATTACTCGCGCTTCACC
GAGCAGCCGAGCGGTGACTTCTTCGGCACGGCGGCGCTCGACGGCGTCGAGCGCTGGTATGCGTTCCGCCATATCGACAT
GTATCCGCTGATCCTCGACGTCGCGCTGTCCACGCGTGACATCTACGCGCAATGGCGGCACCGTGCATGGATCATCGGCT
CGCTGATCGCCGCGCTCGACGTGACGATCATCGCGCTGGCCGTCCTGTTCTCCCAGCAACTGCGGCATCGCCGCGCGGCC
GAAGAAGAGTTGCGCGTGCTGGCGTGCACCGACGGCCTGACCGGCCTCTTCAACCGCCGGACCTATGAGCAGCAGGCGGA
AGGAGAGTGGCGCCGCGCGCAGCGCAACGCGCGTCCGTTGTCGATGCTGCTGATCGACGTCGACAATTTCAAGGGTTTCA
ACGACCTGTACGGCCACTCGGCGGGCGACGAAGCGCTGATCGGCGTAGCGCGTTGCATTTCGCAGAGCGTGCGGCGCCCC
GGCGACACGGCGGCGCGCTACGGCGGCGAAGAGTTTGCCGTGCTGCTGCCGGATACCGACGAAGCCGGCGCAACCCGCAT
TGCCGGGAAGATCTGCGCCGCGGTTGAAGCGCTGCAGCTTCGCCACGTGGCGAGTTCGCACTGCGTGCTGACGGTGAGCA
TTGGTGTCGCGACCACGCGAGGCCAGGCATTTGCCACGAGCCGCGCGCTCGTGGACGCCGCCGACGAGGCCCTTTACGAA
GCCAAGGATGCCGGCCGCAATTGCGTGCTGTGCTTTGGCGCGACGACCCACGCGACCCACGCGATGCATGCGACGCTGGG
CACCACCTCCGTAGCGGGCACGGGCACTAAGAAGCTGTTGCGAAATTAG

Upstream 100 bases:

>100_bases
TCGTCGATAATTCCGCGCGTCACAGCGTCTGGTACGCTACCGGTTCACGGTACGCGCCTATCCGGACGCGGCCCTCCTGT
TCACGCGCATTGGTCCGCGC

Downstream 100 bases:

>100_bases
TTAAACAGAGGCTTTAGGCGCGTCCAGCAAATTAAGGCGCAAGCCAAAGACAGGAATGCTTCGTGAACATGCGCATAGCG
TTCGTAACGAATCTTGAGCC

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MPERQVMVTRRPNIVIAISIVLASAILAIAVWVLAQMRDDALRRAQDSVFNVSLLVERDVSRNLEIYDLSLRAVLDGLKQ
PGVLDLKPAMRQMVLFDGSASAKDMGSILVTDEAGNVRFDSQATPPRQVNLADRDYFKVQRDSPNAGLFISHPFIPKVGG
KDVSIALSRRITRPDGGFGGVVAGTMRLTYFHSLFAGMNLGVGGSMALMLSDGTMLMRRPYDPKMIGINLTGTANYSRFT
EQPSGDFFGTAALDGVERWYAFRHIDMYPLILDVALSTRDIYAQWRHRAWIIGSLIAALDVTIIALAVLFSQQLRHRRAA
EEELRVLACTDGLTGLFNRRTYEQQAEGEWRRAQRNARPLSMLLIDVDNFKGFNDLYGHSAGDEALIGVARCISQSVRRP
GDTAARYGGEEFAVLLPDTDEAGATRIAGKICAAVEALQLRHVASSHCVLTVSIGVATTRGQAFATSRALVDAADEALYE
AKDAGRNCVLCFGATTHATHAMHATLGTTSVAGTGTKKLLRN

Sequences:

>Translated_522_residues
MPERQVMVTRRPNIVIAISIVLASAILAIAVWVLAQMRDDALRRAQDSVFNVSLLVERDVSRNLEIYDLSLRAVLDGLKQ
PGVLDLKPAMRQMVLFDGSASAKDMGSILVTDEAGNVRFDSQATPPRQVNLADRDYFKVQRDSPNAGLFISHPFIPKVGG
KDVSIALSRRITRPDGGFGGVVAGTMRLTYFHSLFAGMNLGVGGSMALMLSDGTMLMRRPYDPKMIGINLTGTANYSRFT
EQPSGDFFGTAALDGVERWYAFRHIDMYPLILDVALSTRDIYAQWRHRAWIIGSLIAALDVTIIALAVLFSQQLRHRRAA
EEELRVLACTDGLTGLFNRRTYEQQAEGEWRRAQRNARPLSMLLIDVDNFKGFNDLYGHSAGDEALIGVARCISQSVRRP
GDTAARYGGEEFAVLLPDTDEAGATRIAGKICAAVEALQLRHVASSHCVLTVSIGVATTRGQAFATSRALVDAADEALYE
AKDAGRNCVLCFGATTHATHAMHATLGTTSVAGTGTKKLLRN
>Mature_521_residues
PERQVMVTRRPNIVIAISIVLASAILAIAVWVLAQMRDDALRRAQDSVFNVSLLVERDVSRNLEIYDLSLRAVLDGLKQP
GVLDLKPAMRQMVLFDGSASAKDMGSILVTDEAGNVRFDSQATPPRQVNLADRDYFKVQRDSPNAGLFISHPFIPKVGGK
DVSIALSRRITRPDGGFGGVVAGTMRLTYFHSLFAGMNLGVGGSMALMLSDGTMLMRRPYDPKMIGINLTGTANYSRFTE
QPSGDFFGTAALDGVERWYAFRHIDMYPLILDVALSTRDIYAQWRHRAWIIGSLIAALDVTIIALAVLFSQQLRHRRAAE
EELRVLACTDGLTGLFNRRTYEQQAEGEWRRAQRNARPLSMLLIDVDNFKGFNDLYGHSAGDEALIGVARCISQSVRRPG
DTAARYGGEEFAVLLPDTDEAGATRIAGKICAAVEALQLRHVASSHCVLTVSIGVATTRGQAFATSRALVDAADEALYEA
KDAGRNCVLCFGATTHATHAMHATLGTTSVAGTGTKKLLRN

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=36.046511627907, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87081881, Length=185, Percent_Identity=39.4594594594595, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693134, Length=200, Percent_Identity=37.5, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1787262, Length=211, Percent_Identity=34.1232227488152, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082007, Length=171, Percent_Identity=34.5029239766082, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=35.1190476190476, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788085, Length=175, Percent_Identity=33.1428571428571, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787802, Length=161, Percent_Identity=37.2670807453416, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788381, Length=201, Percent_Identity=30.8457711442786, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787541, Length=175, Percent_Identity=33.7142857142857, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081974, Length=154, Percent_Identity=30.5194805194805, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081977, Length=148, Percent_Identity=33.1081081081081, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788956, Length=176, Percent_Identity=32.9545454545455, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 56932; Mature: 56801

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERQVMVTRRPNIVIAISIVLASAILAIAVWVLAQMRDDALRRAQDSVFNVSLLVERDV
CCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
SRNLEIYDLSLRAVLDGLKQPGVLDLKPAMRQMVLFDGSASAKDMGSILVTDEAGNVRFD
CCCCEEEEEHHHHHHHHCCCCCEEECCHHHHHEEEECCCCCCCCCCCEEEEECCCCEEEC
SQATPPRQVNLADRDYFKVQRDSPNAGLFISHPFIPKVGGKDVSIALSRRITRPDGGFGG
CCCCCCCEECCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCC
VVAGTMRLTYFHSLFAGMNLGVGGSMALMLSDGTMLMRRPYDPKMIGINLTGTANYSRFT
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEECCCCCEEEEEEEECCCCCHHHC
EQPSGDFFGTAALDGVERWYAFRHIDMYPLILDVALSTRDIYAQWRHRAWIIGSLIAALD
CCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTIIALAVLFSQQLRHRRAAEEELRVLACTDGLTGLFNRRTYEQQAEGEWRRAQRNARPL
HHHHHHHHHHHHHHHHHHCCHHHCEEEEECCCHHHHHCCCCHHHHHCCHHHHHHCCCCCE
SMLLIDVDNFKGFNDLYGHSAGDEALIGVARCISQSVRRPGDTAARYGGEEFAVLLPDTD
EEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEECCCC
EAGATRIAGKICAAVEALQLRHVASSHCVLTVSIGVATTRGQAFATSRALVDAADEALYE
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEEECCCHHHHHHHHHHHHHHHHHH
AKDAGRNCVLCFGATTHATHAMHATLGTTSVAGTGTKKLLRN
HHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure 
PERQVMVTRRPNIVIAISIVLASAILAIAVWVLAQMRDDALRRAQDSVFNVSLLVERDV
CCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
SRNLEIYDLSLRAVLDGLKQPGVLDLKPAMRQMVLFDGSASAKDMGSILVTDEAGNVRFD
CCCCEEEEEHHHHHHHHCCCCCEEECCHHHHHEEEECCCCCCCCCCCEEEEECCCCEEEC
SQATPPRQVNLADRDYFKVQRDSPNAGLFISHPFIPKVGGKDVSIALSRRITRPDGGFGG
CCCCCCCEECCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCC
VVAGTMRLTYFHSLFAGMNLGVGGSMALMLSDGTMLMRRPYDPKMIGINLTGTANYSRFT
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEECCCCCEEEEEEEECCCCCHHHC
EQPSGDFFGTAALDGVERWYAFRHIDMYPLILDVALSTRDIYAQWRHRAWIIGSLIAALD
CCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTIIALAVLFSQQLRHRRAAEEELRVLACTDGLTGLFNRRTYEQQAEGEWRRAQRNARPL
HHHHHHHHHHHHHHHHHHCCHHHCEEEEECCCHHHHHCCCCHHHHHCCHHHHHHCCCCCE
SMLLIDVDNFKGFNDLYGHSAGDEALIGVARCISQSVRRPGDTAARYGGEEFAVLLPDTD
EEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEECCCC
EAGATRIAGKICAAVEALQLRHVASSHCVLTVSIGVATTRGQAFATSRALVDAADEALYE
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEEECCCHHHHHHHHHHHHHHHHHH
AKDAGRNCVLCFGATTHATHAMHATLGTTSVAGTGTKKLLRN
HHHCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]