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The map label for this gene is yjcC [H]

Identifier: 91781553

GI number: 91781553

Start: 197537

End: 198814

Strand: Direct

Name: yjcC [H]

Synonym: Bxe_A4292

Alternate gene names: 91781553

Gene position: 197537-198814 (Clockwise)

Preceding gene: 91781551

Following gene: 91781554

Centisome position: 4.03

GC content: 66.35

Gene sequence:

>1278_bases
ATGACGATTGCGCAACAGGAAAGGACGGCCGGCGCGCCGCATGGCTTCGATGTCGAGATGACGTCGGGGCTCGAACGTTT
TACGGTGAAGCATGGCGAACTCACGCTGAGCAGCGTGTTCCAGCCGATTTTCAGCCTCTCGCATATGCGGGCGGTCGGCT
ACGAGGGCTTGCTGCGCGCGCATGACGCGCTCGATCGGCCCGTGTCGCCGCTCGACGTGTTCGGCGAGGCCGCGCGCCTC
GGCGAAGTGCTGCAGGTGGACAGGCTCGCGCAGACTCTGCATCTGGAGAATTTCAAGGTGCTCGGCGCCGAGCGTGAGTG
GCTGTTCCTGAACGTGCATCCCGCGGCGCTCACCGATCCCTATCTGGCGGCCGCGTTGCTGGCCACGCTGAAGCGGCTCG
ACCTGTCGCCGCGGCGCATCGTGCTCGAGGTGCTGGAGCATCGCGCGGAAGATCTGGAGCGTCTCGCCGACGCCGTGCGG
CAGTTCCGCGAGCGCGGTTTCCTGATCGCGCTCGACGACTTCGGCGCGGGACACTCGAACGTCGAGCGGATCTGGCAATT
GAATCCCGATATCGTGAAACTCGACCGCATCATGCTGTCGCACGCAGCGCACCGCGCGGACATGGCGACGATTCTGCCCG
GCCTCGTCGCGCTGCTGCACGAAGCAGGCAAGCTCGTGCTCATCGAAGGCGTGGAAACGGAGCATGAAGCGCAGATGGCG
CTCGCCTGCAACGCGGACTTCGTGCAAGGCTTTTTCTTCGGCCGCCCGAATCCGGGTGCGGCCGACGCGTTGCACGCGAC
CACCTGCATCAGCGAACTGACCGAGCGTTACCGCGACCAGGCCGAAGCACGCGAGCGCCGCAATGCCAGCCGGCTCGCGC
CGTACCTGCGGGCTTTCGAGCGGGCGGCGGAACGCCTCGCGGCCGGCGAACCGCTCGAAGAGGTGTGCTGGAATTTTCTT
GCGCTGGACCATGCCGCGCGCTGCTTCCTGCTCGACGCGAAGGGCAGGCAGGCGGGCCGCAACGTCGTGCTGCGCGCCGA
CCGTGCGGCGCATGAAACGCGCTTTCTGCCGCTGGCCGACGCGCAAGGGGCGAACTGGCTGCGTCGCCCGTATTTTCGCG
ACGCGATCAATGCGCCGGAACGGGTGCATGTGACGCGCCCTTATCTGTCGATCAACGAGGCGTTGCCGTGCGTCACGCTT
TCCGTGGCGACGCGGGTTGGCGAGCAGACCTGCGTGCTGTGCGGCGACATCGACTGGGTGGACGAAGAGCGTTATTGA

Upstream 100 bases:

>100_bases
AGCTTGCTTAAGGTATATCGATGACGCACATTTGAGAGACGGCGCCGAGGTTGTTCGCCTTCGCGTTCGGACCGGCCCGG
CTCTCGCGTGAGAGGACTGC

Downstream 100 bases:

>100_bases
GTGTTGAGTGTGCCGCCTGACTGTCGCCCTGCGACGATTCCTTTCGGGGGTGACAAAACTACCAGGGGCGGCGCGGCGTA
TTTTTGGGGGATCATGTCGG

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTIAQQERTAGAPHGFDVEMTSGLERFTVKHGELTLSSVFQPIFSLSHMRAVGYEGLLRAHDALDRPVSPLDVFGEAARL
GEVLQVDRLAQTLHLENFKVLGAEREWLFLNVHPAALTDPYLAAALLATLKRLDLSPRRIVLEVLEHRAEDLERLADAVR
QFRERGFLIALDDFGAGHSNVERIWQLNPDIVKLDRIMLSHAAHRADMATILPGLVALLHEAGKLVLIEGVETEHEAQMA
LACNADFVQGFFFGRPNPGAADALHATTCISELTERYRDQAEARERRNASRLAPYLRAFERAAERLAAGEPLEEVCWNFL
ALDHAARCFLLDAKGRQAGRNVVLRADRAAHETRFLPLADAQGANWLRRPYFRDAINAPERVHVTRPYLSINEALPCVTL
SVATRVGEQTCVLCGDIDWVDEERY

Sequences:

>Translated_425_residues
MTIAQQERTAGAPHGFDVEMTSGLERFTVKHGELTLSSVFQPIFSLSHMRAVGYEGLLRAHDALDRPVSPLDVFGEAARL
GEVLQVDRLAQTLHLENFKVLGAEREWLFLNVHPAALTDPYLAAALLATLKRLDLSPRRIVLEVLEHRAEDLERLADAVR
QFRERGFLIALDDFGAGHSNVERIWQLNPDIVKLDRIMLSHAAHRADMATILPGLVALLHEAGKLVLIEGVETEHEAQMA
LACNADFVQGFFFGRPNPGAADALHATTCISELTERYRDQAEARERRNASRLAPYLRAFERAAERLAAGEPLEEVCWNFL
ALDHAARCFLLDAKGRQAGRNVVLRADRAAHETRFLPLADAQGANWLRRPYFRDAINAPERVHVTRPYLSINEALPCVTL
SVATRVGEQTCVLCGDIDWVDEERY
>Mature_424_residues
TIAQQERTAGAPHGFDVEMTSGLERFTVKHGELTLSSVFQPIFSLSHMRAVGYEGLLRAHDALDRPVSPLDVFGEAARLG
EVLQVDRLAQTLHLENFKVLGAEREWLFLNVHPAALTDPYLAAALLATLKRLDLSPRRIVLEVLEHRAEDLERLADAVRQ
FRERGFLIALDDFGAGHSNVERIWQLNPDIVKLDRIMLSHAAHRADMATILPGLVALLHEAGKLVLIEGVETEHEAQMAL
ACNADFVQGFFFGRPNPGAADALHATTCISELTERYRDQAEARERRNASRLAPYLRAFERAAERLAAGEPLEEVCWNFLA
LDHAARCFLLDAKGRQAGRNVVLRADRAAHETRFLPLADAQGANWLRRPYFRDAINAPERVHVTRPYLSINEALPCVTLS
VATRVGEQTCVLCGDIDWVDEERY

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=238, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082096, Length=152, Percent_Identity=30.2631578947368, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787055, Length=247, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081743, Length=231, Percent_Identity=24.6753246753247, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788849, Length=224, Percent_Identity=25.8928571428571, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI226510982, Length=155, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081921, Length=237, Percent_Identity=24.4725738396624, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788502, Length=232, Percent_Identity=26.7241379310345, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787541, Length=153, Percent_Identity=26.797385620915, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 47540; Mature: 47409

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAQQERTAGAPHGFDVEMTSGLERFTVKHGELTLSSVFQPIFSLSHMRAVGYEGLLRA
CCCCCCCCCCCCCCCCCCHHHCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
HDALDRPVSPLDVFGEAARLGEVLQVDRLAQTLHLENFKVLGAEREWLFLNVHPAALTDP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCHHHCCH
YLAAALLATLKRLDLSPRRIVLEVLEHRAEDLERLADAVRQFRERGFLIALDDFGAGHSN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHH
VERIWQLNPDIVKLDRIMLSHAAHRADMATILPGLVALLHEAGKLVLIEGVETEHEAQMA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHEE
LACNADFVQGFFFGRPNPGAADALHATTCISELTERYRDQAEARERRNASRLAPYLRAFE
EECCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RAAERLAAGEPLEEVCWNFLALDHAARCFLLDAKGRQAGRNVVLRADRAAHETRFLPLAD
HHHHHHHCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCEEEEECHHHHHHCCEECCC
AQGANWLRRPYFRDAINAPERVHVTRPYLSINEALPCVTLSVATRVGEQTCVLCGDIDWV
CCCCCHHHCCHHHHHCCCCCEEEEECCCHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCC
DEERY
CCCCC
>Mature Secondary Structure 
TIAQQERTAGAPHGFDVEMTSGLERFTVKHGELTLSSVFQPIFSLSHMRAVGYEGLLRA
CCCCCCCCCCCCCCCCCHHHCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
HDALDRPVSPLDVFGEAARLGEVLQVDRLAQTLHLENFKVLGAEREWLFLNVHPAALTDP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCHHHCCH
YLAAALLATLKRLDLSPRRIVLEVLEHRAEDLERLADAVRQFRERGFLIALDDFGAGHSN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHH
VERIWQLNPDIVKLDRIMLSHAAHRADMATILPGLVALLHEAGKLVLIEGVETEHEAQMA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHEE
LACNADFVQGFFFGRPNPGAADALHATTCISELTERYRDQAEARERRNASRLAPYLRAFE
EECCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RAAERLAAGEPLEEVCWNFLALDHAARCFLLDAKGRQAGRNVVLRADRAAHETRFLPLAD
HHHHHHHCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCEEEEECHHHHHHCCEECCC
AQGANWLRRPYFRDAINAPERVHVTRPYLSINEALPCVTLSVATRVGEQTCVLCGDIDWV
CCCCCHHHCCHHHHHCCCCCEEEEECCCHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCC
DEERY
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]