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The map label for this gene is aroE [H]

Identifier: 89255607

GI number: 89255607

Start: 176824

End: 177597

Strand: Reverse

Name: aroE [H]

Synonym: FTL_0173

Alternate gene names: 89255607

Gene position: 177597-176824 (Counterclockwise)

Preceding gene: 89255620

Following gene: 89255606

Centisome position: 9.37

GC content: 34.63

Gene sequence:

>774_bases
ATGAAAGATTTGTATTATGTGATTGGCTTTCCGGTGAAGCATAGCTTGTCGCCAGCTATTCAAATGAGATTAGCACAGCA
ATATAATCAAGATATGCTTTTTACTGCTATAGAAGTTGCACCACAAGATTTAGAGGCAAAAATCCAAGAATTTAAGACTA
ATCCTCAAGTTAAGGGCTTAAGTGTTACTGTGCCACATAAAGAGAGAGTTTATGCCTTAGCAGATGATGCTGATACTACT
GCTAAAGCTGTTCAGGCAGCTAGCAATATTATATTCACAGCTGAGCGTAAAATGATTGCTTTGAACTATGATGGACTTGG
CATAGTCAATGACATCAAAAATAATTATAAGATTGATTTTGCTGGTAAAAAAGTGCTTGTGGTTGGTGCTGGAGGTGCAG
CAAAAGCGGTCGTTGCAGCAGTCCTTAAAGAATCACCATTATCTCTTAGTATTACAAATAGAACACTAGCCAAAGCCAAA
GCTATTGAAGAGCTTTTTAAAGTTGATACTGAGATTAAAATTATCGATTTTGATAATATTAGTGATTCTTTTGATATAGT
TATTAATTCAACATCATCAAGTATTGATGGTAAGTTACTTCCTTTAAAAGATAGTAATTTCAATAAAAATGCTTTTGCCT
ATGATCTAATGTATGCTGATGGTGGTACTATTTTTACAAAATGGTGTCAAGCTTATAATATTGCTGCAGCAGATGGTAAA
GGGATGCTTAAAGAGCTAAGTATCGCTGTGTTTAAATATTGGCGTGGATTGTGA

Upstream 100 bases:

>100_bases
ATAGCTCTATAATATTTATTTTTTCTTTTGTATTCAAGTCAAGCTAATCATTGTTAGTATGTTATAATCTTAAGATAAAC
TCTTTAAAACGTTTTTATCT

Downstream 100 bases:

>100_bases
TTAAGAATAAGGATTATGCTAAAATATTGTATACCAAATCATTATTAGCATAGTTGCTAGGCTAGTTTGAACAAAAAAAT
ATTATTTCTTGGAGTTGGCG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKDLYYVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGLSVTVPHKERVYALADDADTT
AKAVQAASNIIFTAERKMIALNYDGLGIVNDIKNNYKIDFAGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAK
AIEELFKVDTEIKIIDFDNISDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAYNIAAADGK
GMLKELSIAVFKYWRGL

Sequences:

>Translated_257_residues
MKDLYYVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGLSVTVPHKERVYALADDADTT
AKAVQAASNIIFTAERKMIALNYDGLGIVNDIKNNYKIDFAGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAK
AIEELFKVDTEIKIIDFDNISDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAYNIAAADGK
GMLKELSIAVFKYWRGL
>Mature_257_residues
MKDLYYVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGLSVTVPHKERVYALADDADTT
AKAVQAASNIIFTAERKMIALNYDGLGIVNDIKNNYKIDFAGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAK
AIEELFKVDTEIKIIDFDNISDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAYNIAAADGK
GMLKELSIAVFKYWRGL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=259, Percent_Identity=31.2741312741313, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787983, Length=274, Percent_Identity=24.8175182481752, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320332, Length=268, Percent_Identity=25.3731343283582, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28203; Mature: 28203

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLYYVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGL
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCE
SVTVPHKERVYALADDADTTAKAVQAASNIIFTAERKMIALNYDGLGIVNDIKNNYKIDF
EEECCCCCEEEEEECCCCHHHHHHHHHCCEEEEECCEEEEEECCCCEEHECCCCCEEEEE
AGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAKAIEELFKVDTEIKIIDFDNI
CCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCC
SDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAYNIAAADGK
CCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHCEEEECCCC
GMLKELSIAVFKYWRGL
CHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDLYYVIGFPVKHSLSPAIQMRLAQQYNQDMLFTAIEVAPQDLEAKIQEFKTNPQVKGL
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCE
SVTVPHKERVYALADDADTTAKAVQAASNIIFTAERKMIALNYDGLGIVNDIKNNYKIDF
EEECCCCCEEEEEECCCCHHHHHHHHHCCEEEEECCEEEEEECCCCEEHECCCCCEEEEE
AGKKVLVVGAGGAAKAVVAAVLKESPLSLSITNRTLAKAKAIEELFKVDTEIKIIDFDNI
CCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCC
SDSFDIVINSTSSSIDGKLLPLKDSNFNKNAFAYDLMYADGGTIFTKWCQAYNIAAADGK
CCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHCEEEECCCC
GMLKELSIAVFKYWRGL
CHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA