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The map label for this gene is ydhC [H]

Identifier: 89255620

GI number: 89255620

Start: 185208

End: 186326

Strand: Reverse

Name: ydhC [H]

Synonym: FTL_0186

Alternate gene names: 89255620

Gene position: 186326-185208 (Counterclockwise)

Preceding gene: 89255621

Following gene: 89255607

Centisome position: 9.83

GC content: 30.03

Gene sequence:

>1119_bases
ATGCTTAAAGCGTATCGTATTGCCTTAATTTTTAGTGGCTTGATTGTACTTATAGGATTAATGTCGATCGATTTTATTAG
CCCATCCCTAACCTACATTAAATCTGATTTTGAAACATCTCAAACATTACTTAAAAATAGTGTATTAACCTACATGCTTA
TCCTAGGAATATTTCAACTACCATATGGATTTTTAAGTGATAGATATGGACGTAAGAAACTTGTGTTAATTTCACTATCA
ATAACAATTCTAGGTATTTTAATATCAGCTTTTGCTCAAGGAATCGTTCCTTTCTACATCGGTAGAATTGTAACTGCGAT
TGGTAGTGCTGGTTGTCCTGTAATAAGTAGATCAATAATTGCTGATGTTTCACACAATCCTAAGAGATTAAGGAAATCAT
TTTCTTTATATGCCTTAGCTAGTCAGATATCGCTATGTATTGCACCAGTACTAGGTGCTTTTATACAATCGGTTAGCTCA
TGGAGATTTTCTCTAATAACTCTGCTATTAATAAATATAGTTGTTTTTTTGTTAATCTTGTTAATAATGCCTGAAACTTC
AAGAAGACTTGAATATAAAATAAACTATAAAACCACTTTAGATAAGTATTTGTATTATTTCAAAAATCGTTACTTTTTTA
TAATGAGTCTTCTTTCGGCATTATTTTATGTTTATTCCATAGGTTTTTATAATATGTTACCTTTTGTGTTACATCACTTA
GGCATACCAGTAATTACCAATGGTTTTATAAACAGCTTCTACGCTATAAGTTTGGCCACTGGAGCTTTTTCATTACAACG
TTTCTTATATAGATATGCTTCCGAAAAGATTCTTGCTTTGCTACTTGGATTATTTTTGTTTCATTTTATAGCATTTATAT
TATTGTTTAAGTTATATACAAATACTTTTACCATAATTATATTTGGCATTGGTACAGCTTTTCTATGTGGTATTATCGCG
CCATTAATACTATCAATGTGTATGCAAGGATTCAAAAAAGATAAAGGCATAGCTAGTGCGGTACAAAGTGCTATTAAGAT
GTTTTTTACAGGTGTAGGGTTAATAATATTCTCATACATTAAGCTTGAAAGTATAGTTAATCCGAGAGTATTTTGTTAA

Upstream 100 bases:

>100_bases
CCGACTATCCTTAAAAAATATACAAAATCTTAAATAAAGCTTTGTAATTATCATTTATCATAAGAAAATACCTCTATAAT
CTATCTTGAGTAAACTCTGA

Downstream 100 bases:

>100_bases
ACACATAAGAGATAGCATCACAAAATTTTTCAAAACTATTATTCACTTTTCTAAATATTTTTTTAAAGTTAGCCCAAACC
TTTTCAATAGGATTTAAATC

Product: hypothetical protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLKAYRIALIFSGLIVLIGLMSIDFISPSLTYIKSDFETSQTLLKNSVLTYMLILGIFQLPYGFLSDRYGRKKLVLISLS
ITILGILISAFAQGIVPFYIGRIVTAIGSAGCPVISRSIIADVSHNPKRLRKSFSLYALASQISLCIAPVLGAFIQSVSS
WRFSLITLLLINIVVFLLILLIMPETSRRLEYKINYKTTLDKYLYYFKNRYFFIMSLLSALFYVYSIGFYNMLPFVLHHL
GIPVITNGFINSFYAISLATGAFSLQRFLYRYASEKILALLLGLFLFHFIAFILLFKLYTNTFTIIIFGIGTAFLCGIIA
PLILSMCMQGFKKDKGIASAVQSAIKMFFTGVGLIIFSYIKLESIVNPRVFC

Sequences:

>Translated_372_residues
MLKAYRIALIFSGLIVLIGLMSIDFISPSLTYIKSDFETSQTLLKNSVLTYMLILGIFQLPYGFLSDRYGRKKLVLISLS
ITILGILISAFAQGIVPFYIGRIVTAIGSAGCPVISRSIIADVSHNPKRLRKSFSLYALASQISLCIAPVLGAFIQSVSS
WRFSLITLLLINIVVFLLILLIMPETSRRLEYKINYKTTLDKYLYYFKNRYFFIMSLLSALFYVYSIGFYNMLPFVLHHL
GIPVITNGFINSFYAISLATGAFSLQRFLYRYASEKILALLLGLFLFHFIAFILLFKLYTNTFTIIIFGIGTAFLCGIIA
PLILSMCMQGFKKDKGIASAVQSAIKMFFTGVGLIIFSYIKLESIVNPRVFC
>Mature_372_residues
MLKAYRIALIFSGLIVLIGLMSIDFISPSLTYIKSDFETSQTLLKNSVLTYMLILGIFQLPYGFLSDRYGRKKLVLISLS
ITILGILISAFAQGIVPFYIGRIVTAIGSAGCPVISRSIIADVSHNPKRLRKSFSLYALASQISLCIAPVLGAFIQSVSS
WRFSLITLLLINIVVFLLILLIMPETSRRLEYKINYKTTLDKYLYYFKNRYFFIMSLLSALFYVYSIGFYNMLPFVLHHL
GIPVITNGFINSFYAISLATGAFSLQRFLYRYASEKILALLLGLFLFHFIAFILLFKLYTNTFTIIIFGIGTAFLCGIIA
PLILSMCMQGFKKDKGIASAVQSAIKMFFTGVGLIIFSYIKLESIVNPRVFC

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=362, Percent_Identity=25.414364640884, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082312, Length=352, Percent_Identity=23.0113636363636, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41864; Mature: 41864

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAYRIALIFSGLIVLIGLMSIDFISPSLTYIKSDFETSQTLLKNSVLTYMLILGIFQL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PYGFLSDRYGRKKLVLISLSITILGILISAFAQGIVPFYIGRIVTAIGSAGCPVISRSII
CHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ADVSHNPKRLRKSFSLYALASQISLCIAPVLGAFIQSVSSWRFSLITLLLINIVVFLLIL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIMPETSRRLEYKINYKTTLDKYLYYFKNRYFFIMSLLSALFYVYSIGFYNMLPFVLHHL
HHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIPVITNGFINSFYAISLATGAFSLQRFLYRYASEKILALLLGLFLFHFIAFILLFKLYT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTFTIIIFGIGTAFLCGIIAPLILSMCMQGFKKDKGIASAVQSAIKMFFTGVGLIIFSYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLESIVNPRVFC
HHHHHCCCCCCC
>Mature Secondary Structure
MLKAYRIALIFSGLIVLIGLMSIDFISPSLTYIKSDFETSQTLLKNSVLTYMLILGIFQL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PYGFLSDRYGRKKLVLISLSITILGILISAFAQGIVPFYIGRIVTAIGSAGCPVISRSII
CHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ADVSHNPKRLRKSFSLYALASQISLCIAPVLGAFIQSVSSWRFSLITLLLINIVVFLLIL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIMPETSRRLEYKINYKTTLDKYLYYFKNRYFFIMSLLSALFYVYSIGFYNMLPFVLHHL
HHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIPVITNGFINSFYAISLATGAFSLQRFLYRYASEKILALLLGLFLFHFIAFILLFKLYT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTFTIIIFGIGTAFLCGIIAPLILSMCMQGFKKDKGIASAVQSAIKMFFTGVGLIIFSYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLESIVNPRVFC
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]