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The map label for this gene is 89056302

Identifier: 89056302

GI number: 89056302

Start: 3897542

End: 3899623

Strand: Direct

Name: 89056302

Synonym: Jann_3811

Alternate gene names: NA

Gene position: 3897542-3899623 (Clockwise)

Preceding gene: 89056301

Following gene: 89056303

Centisome position: 90.26

GC content: 62.78

Gene sequence:

>2082_bases
ATGTCCTCTGCCCCCTACCGCCTTGGTGTCGATATCGGCGGGACCTTCACGGATGTCGTTCTGGAAGGCGCAGGCCAGCA
GCACTCCACCAAGGTGCTGACGACCTATGCGGCCCCAGAGGATGCGATTATCGACGGGATGCAGCAGGTCTGCGCCAAGG
CAGGCATCACCCCCGGTCAGATCACGCAGATCATCCATGGCACGACGCTGGCCACCAATGCCCTGATTGAGCGACGCGGG
GCCAGGACGGCCCTGATCACGACGGAGGGCTTCCGCGATGTGATCGAGATGCGGACGGAAAGCCGGTTCGAGCAATATGA
CCTGAATTTGCAACTGCCCGAGCCGCTGTTGCCGCGTCAGATGCGATTTACCGTGGCGGAACGGGTGAACGCCAAGGGCG
AGGTGATGGTTAACCTTGATGAAGCTAGCGTTCGGGAGGTGGCAGGCCGGATCAGGGAAGCGGGGTTTGAGAGCGTCGCC
GTTGGGCTGATCCATTCCTACCTCAACCCCGCCCATGAAAAGATGGTGCGCGACGTTCTGGCAGAGGTTGTACCAGGCGT
GTCGGTTTCCCTGTCCTCCGAGGTCTCGCCGCAGATGCGGGAGTATGAGCGGTTCAACACCGTCGTGGCCAACGCCTATA
TCAAGCCGCTGATGTCATCGTATCTGGGACGGCTGAAGAAGAGGTTGGGCGATGAGGGCGTGACCTGCCGCATCTTTCTG
ATGCATTCGGGTGGGGGGATTATCTCGATCCAGAACGCAGCGGAATTTCCTGTACGGCTGGTGGAATCCGGGCCCGCCGG
TGGCGCGGTGTTCGCGGCCCACATCGCAGCGCGCTACGGGTTGGACAAAGTGTTGTCCTTCGACATGGGCGGTACCACGG
CGAAGATCTGCCTGATCAAGAACCAGACGCCGAAGACCAGCCGCGTGTTTGAAGTGGCGCGGACATATCGGTTCAAGAAA
GGATCGGGCATGCCTATATCAATTCCTGTAATTGATATGGTCGAGATTGGCGCGGGCGGCGGATCACTGGCCCATGTGGA
TGCGATGCGCCAGATCCGCGTGGGGCCGGAAAGCGCCGGGTCCGAACCCGGGCCAGCCTGCTACGGGCGCGGTGGGAACC
GGCCTGCGGTCACCGATGCGGACCTGATCCTTGGTAAGCTGGACCCGGACAATTTCGCCGGAGGCTCCATCGTCCTTGAT
CCCTCAGCCGCCTCCTCCGCCCTTGAGGGCGTCCTCGGCGCTGCGCTGGGGATGGACGCCGTGGAAGCCGCCTTCGGCGT
CGCGGAGGTCGTGGACGAAAACATGGCCAACGCCGCGCGGGTTCACGCGGTGGAGAACGGCGAGGACCTGAGCGACTACA
CCATGATCGCCTTCGGCGGCGCGGCCCCGCTGCATGGGGGTCGGCTGTGCGAGAAATTGGGCATTGCCCGCTGCCTTGTT
CCACCCGGCGCAGGGGTGGGCAGTGCCATCGGGTTCCTGCGTGCGCCGTTTTCGTTCGAGGCCAACCGGTCGGTCTATAT
GACGCTGTCGGACTTTGATCCGCAGGTAATCAAGACGCTTCTGTCGGAACTTCAGACCGAGGCGATCGGCTTCGTGCGCA
CCTGCGATGCGAACGCGCCGATCCACTCTGAATTCAAGGTCTACATGCGCTATACCGGGCAAGGGTGGGAGATCCCCATC
GACCTGTCCGAAGCTCAGGCCATGACCCCTGACGCCGCCACCTTCCAGACGCGGTTTGAAGAGGATTACGCCAAGCTCTT
CGGGCGCACGGTGGCGGGCATGGATATTGAGATCACGGTCTGGTCCGTCAACGCGACAACCCCACCCGAACCGGTTGCGC
GGATGACGGAAGCGCAGAGCACGGACGCCGCTGCCGCCACGCTTGGCACGCGCAATCTGTTCGACCCTGCCCAGGGCGCA
TTCCTTGAGGCTGCCGTGATCGACCGGACGGCCATGGGCATTGGTCAGATCGCCCAGGGCCCCGCCACAATCACCGAGGA
TGAAACGACGATCATCCTGCCCGCCAGCCGCCGCGCCTCTTGTCAGCCTGACGGCTGCATCGACCTTGTGAAGAAGGATT
GA

Upstream 100 bases:

>100_bases
AGGATAAAATTTCCTTATCGGTGGTGGTATTTCTATTGATTTGACGTCTCCAAGCCGCTGCCGTTCTATGGTGTCCTGCA
CGCACCTACGGAGCCCTACC

Downstream 100 bases:

>100_bases
GCCGATGAGTGCTTCAAACGACGCCGGGCCCGGCAATGTCGCCTACCAAGTCATGTGGAACCGCCTGATCTCCATCGTGG
AGGAACAGGCGCAAGCGTTG

Product: 5-oxoprolinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MSSAPYRLGVDIGGTFTDVVLEGAGQQHSTKVLTTYAAPEDAIIDGMQQVCAKAGITPGQITQIIHGTTLATNALIERRG
ARTALITTEGFRDVIEMRTESRFEQYDLNLQLPEPLLPRQMRFTVAERVNAKGEVMVNLDEASVREVAGRIREAGFESVA
VGLIHSYLNPAHEKMVRDVLAEVVPGVSVSLSSEVSPQMREYERFNTVVANAYIKPLMSSYLGRLKKRLGDEGVTCRIFL
MHSGGGIISIQNAAEFPVRLVESGPAGGAVFAAHIAARYGLDKVLSFDMGGTTAKICLIKNQTPKTSRVFEVARTYRFKK
GSGMPISIPVIDMVEIGAGGGSLAHVDAMRQIRVGPESAGSEPGPACYGRGGNRPAVTDADLILGKLDPDNFAGGSIVLD
PSAASSALEGVLGAALGMDAVEAAFGVAEVVDENMANAARVHAVENGEDLSDYTMIAFGGAAPLHGGRLCEKLGIARCLV
PPGAGVGSAIGFLRAPFSFEANRSVYMTLSDFDPQVIKTLLSELQTEAIGFVRTCDANAPIHSEFKVYMRYTGQGWEIPI
DLSEAQAMTPDAATFQTRFEEDYAKLFGRTVAGMDIEITVWSVNATTPPEPVARMTEAQSTDAAAATLGTRNLFDPAQGA
FLEAAVIDRTAMGIGQIAQGPATITEDETTIILPASRRASCQPDGCIDLVKKD

Sequences:

>Translated_693_residues
MSSAPYRLGVDIGGTFTDVVLEGAGQQHSTKVLTTYAAPEDAIIDGMQQVCAKAGITPGQITQIIHGTTLATNALIERRG
ARTALITTEGFRDVIEMRTESRFEQYDLNLQLPEPLLPRQMRFTVAERVNAKGEVMVNLDEASVREVAGRIREAGFESVA
VGLIHSYLNPAHEKMVRDVLAEVVPGVSVSLSSEVSPQMREYERFNTVVANAYIKPLMSSYLGRLKKRLGDEGVTCRIFL
MHSGGGIISIQNAAEFPVRLVESGPAGGAVFAAHIAARYGLDKVLSFDMGGTTAKICLIKNQTPKTSRVFEVARTYRFKK
GSGMPISIPVIDMVEIGAGGGSLAHVDAMRQIRVGPESAGSEPGPACYGRGGNRPAVTDADLILGKLDPDNFAGGSIVLD
PSAASSALEGVLGAALGMDAVEAAFGVAEVVDENMANAARVHAVENGEDLSDYTMIAFGGAAPLHGGRLCEKLGIARCLV
PPGAGVGSAIGFLRAPFSFEANRSVYMTLSDFDPQVIKTLLSELQTEAIGFVRTCDANAPIHSEFKVYMRYTGQGWEIPI
DLSEAQAMTPDAATFQTRFEEDYAKLFGRTVAGMDIEITVWSVNATTPPEPVARMTEAQSTDAAAATLGTRNLFDPAQGA
FLEAAVIDRTAMGIGQIAQGPATITEDETTIILPASRRASCQPDGCIDLVKKD
>Mature_692_residues
SSAPYRLGVDIGGTFTDVVLEGAGQQHSTKVLTTYAAPEDAIIDGMQQVCAKAGITPGQITQIIHGTTLATNALIERRGA
RTALITTEGFRDVIEMRTESRFEQYDLNLQLPEPLLPRQMRFTVAERVNAKGEVMVNLDEASVREVAGRIREAGFESVAV
GLIHSYLNPAHEKMVRDVLAEVVPGVSVSLSSEVSPQMREYERFNTVVANAYIKPLMSSYLGRLKKRLGDEGVTCRIFLM
HSGGGIISIQNAAEFPVRLVESGPAGGAVFAAHIAARYGLDKVLSFDMGGTTAKICLIKNQTPKTSRVFEVARTYRFKKG
SGMPISIPVIDMVEIGAGGGSLAHVDAMRQIRVGPESAGSEPGPACYGRGGNRPAVTDADLILGKLDPDNFAGGSIVLDP
SAASSALEGVLGAALGMDAVEAAFGVAEVVDENMANAARVHAVENGEDLSDYTMIAFGGAAPLHGGRLCEKLGIARCLVP
PGAGVGSAIGFLRAPFSFEANRSVYMTLSDFDPQVIKTLLSELQTEAIGFVRTCDANAPIHSEFKVYMRYTGQGWEIPID
LSEAQAMTPDAATFQTRFEEDYAKLFGRTVAGMDIEITVWSVNATTPPEPVARMTEAQSTDAAAATLGTRNLFDPAQGAF
LEAAVIDRTAMGIGQIAQGPATITEDETTIILPASRRASCQPDGCIDLVKKD

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=762, Percent_Identity=28.6089238845144, Blast_Score=202, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI133901900, Length=396, Percent_Identity=33.5858585858586, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322634, Length=749, Percent_Identity=27.9038718291055, Blast_Score=203, Evalue=8e-53,
Organism=Drosophila melanogaster, GI45550492, Length=739, Percent_Identity=29.3640054127199, Blast_Score=212, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 73727; Mature: 73596

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAPYRLGVDIGGTFTDVVLEGAGQQHSTKVLTTYAAPEDAIIDGMQQVCAKAGITPGQ
CCCCCEEEEEECCCHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHH
ITQIIHGTTLATNALIERRGARTALITTEGFRDVIEMRTESRFEQYDLNLQLPEPLLPRQ
HHHHHCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHH
MRFTVAERVNAKGEVMVNLDEASVREVAGRIREAGFESVAVGLIHSYLNPAHEKMVRDVL
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHH
AEVVPGVSVSLSSEVSPQMREYERFNTVVANAYIKPLMSSYLGRLKKRLGDEGVTCRIFL
HHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
MHSGGGIISIQNAAEFPVRLVESGPAGGAVFAAHIAARYGLDKVLSFDMGGTTAKICLIK
EECCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCHHHHHEECCCCCEEEEEEEE
NQTPKTSRVFEVARTYRFKKGSGMPISIPVIDMVEIGAGGGSLAHVDAMRQIRVGPESAG
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
SEPGPACYGRGGNRPAVTDADLILGKLDPDNFAGGSIVLDPSAASSALEGVLGAALGMDA
CCCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHCHHH
VEAAFGVAEVVDENMANAARVHAVENGEDLSDYTMIAFGGAAPLHGGRLCEKLGIARCLV
HHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEC
PPGAGVGSAIGFLRAPFSFEANRSVYMTLSDFDPQVIKTLLSELQTEAIGFVRTCDANAP
CCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCEEEECCCCCC
IHSEFKVYMRYTGQGWEIPIDLSEAQAMTPDAATFQTRFEEDYAKLFGRTVAGMDIEITV
CCCCEEEEEEECCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
WSVNATTPPEPVARMTEAQSTDAAAATLGTRNLFDPAQGAFLEAAVIDRTAMGIGQIAQG
EEECCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHCCHHHCCC
PATITEDETTIILPASRRASCQPDGCIDLVKKD
CCEEECCCEEEEEECCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure 
SSAPYRLGVDIGGTFTDVVLEGAGQQHSTKVLTTYAAPEDAIIDGMQQVCAKAGITPGQ
CCCCEEEEEECCCHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHH
ITQIIHGTTLATNALIERRGARTALITTEGFRDVIEMRTESRFEQYDLNLQLPEPLLPRQ
HHHHHCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHH
MRFTVAERVNAKGEVMVNLDEASVREVAGRIREAGFESVAVGLIHSYLNPAHEKMVRDVL
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHH
AEVVPGVSVSLSSEVSPQMREYERFNTVVANAYIKPLMSSYLGRLKKRLGDEGVTCRIFL
HHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
MHSGGGIISIQNAAEFPVRLVESGPAGGAVFAAHIAARYGLDKVLSFDMGGTTAKICLIK
EECCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCHHHHHEECCCCCEEEEEEEE
NQTPKTSRVFEVARTYRFKKGSGMPISIPVIDMVEIGAGGGSLAHVDAMRQIRVGPESAG
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCC
SEPGPACYGRGGNRPAVTDADLILGKLDPDNFAGGSIVLDPSAASSALEGVLGAALGMDA
CCCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHCHHH
VEAAFGVAEVVDENMANAARVHAVENGEDLSDYTMIAFGGAAPLHGGRLCEKLGIARCLV
HHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEC
PPGAGVGSAIGFLRAPFSFEANRSVYMTLSDFDPQVIKTLLSELQTEAIGFVRTCDANAP
CCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCEEEECCCCCC
IHSEFKVYMRYTGQGWEIPIDLSEAQAMTPDAATFQTRFEEDYAKLFGRTVAGMDIEITV
CCCCEEEEEEECCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
WSVNATTPPEPVARMTEAQSTDAAAATLGTRNLFDPAQGAFLEAAVIDRTAMGIGQIAQG
EEECCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHCCHHHCCC
PATITEDETTIILPASRRASCQPDGCIDLVKKD
CCEEECCCEEEEEECCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]