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The map label for this gene is ampR [H]

Identifier: 89056301

GI number: 89056301

Start: 3896567

End: 3897448

Strand: Direct

Name: ampR [H]

Synonym: Jann_3810

Alternate gene names: 89056301

Gene position: 3896567-3897448 (Clockwise)

Preceding gene: 89056300

Following gene: 89056302

Centisome position: 90.24

GC content: 62.93

Gene sequence:

>882_bases
ATGATCAAAAGTCGGGTGACCTTCAAGCAACTTGAAGCCTTCGTTTGCGTCGTGGATACGGGCACGTTTCGCAAAGCGGC
CGGTATTCTCGGGACGACGCAGCCCAATATCTCCACCCGGATCGCCGCGCTGGAGGACGTGCTGGGGACCATCCTGATGC
ACCGGGATGCGGGCTCAATTCGCGTGACCGACAAAGGAGCGGAACTGTTGGAGGCCGCACGGGAAATCCTGCGGGCCGGC
GAGAACTTTTTGGAAATCGCTGGCCGCCAAGACCTGATTGAAGATCGCCTCCGCCTTGGCGTGACAGAACTTGTCGCCTG
CACCTGGCTCCATGACTTCTTGCGCGCGTTCAAAGATCTTTATCCAGCGGTGCGGGTGGAGTTGGACGTGAACCTGTCGA
CAGAGATCGAGAAGGCGCTGATCACCCATCAGGTGGATCTGGCGCTGCAAACGGGGCCCTTCGCACGGCCTGTTCCCGGC
ACCTTACCGCTTGGCGACTATCCCTATTGCTGGGTTGCAGCGCCGTCCCTGACCCCGCCCGCAAGCTTTGCGGCGCTCTT
CGACGGTCCTGTGATCAGCCATGGTCGCGACACGCGCGCCTCCCGCGCATTGGCGGAGCACGCGCGGGCGGAGGGGGTAG
CCGTCAACCAGATCGTCCATTCCAGCAGCCTGACATCTTGCGTCGCCATGGCCGTAGACGCCATGGGCCCGGCGCTGTTG
CCGCGTCTGATGGTGGAGGACGCGATAGCACAGGGGCGGTTGTCTGAGTTCACCTGCGGTTGGCTGCCGGATCAGTTGCA
GCTCTTCGCCCGCTTCGATCCCCGCCGCACACCGCAATTCGTCCGCGCCGCAGCCGACCTGGCCGTCGAGATCGCAGGAT
AA

Upstream 100 bases:

>100_bases
TATTGCACACGGGTCATCACCCGGGTGACAGGACATCGACTCTCAGCCGCAATGCAGCTTACCTGCGGTAAGATCTGTTT
TTCTTATCGGACGTGCGCAG

Downstream 100 bases:

>100_bases
AATTTCCTTATCGGTGGTGGTATTTCTATTGATTTGACGTCTCCAAGCCGCTGCCGTTCTATGGTGTCCTGCACGCACCT
ACGGAGCCCTACCATGTCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MIKSRVTFKQLEAFVCVVDTGTFRKAAGILGTTQPNISTRIAALEDVLGTILMHRDAGSIRVTDKGAELLEAAREILRAG
ENFLEIAGRQDLIEDRLRLGVTELVACTWLHDFLRAFKDLYPAVRVELDVNLSTEIEKALITHQVDLALQTGPFARPVPG
TLPLGDYPYCWVAAPSLTPPASFAALFDGPVISHGRDTRASRALAEHARAEGVAVNQIVHSSSLTSCVAMAVDAMGPALL
PRLMVEDAIAQGRLSEFTCGWLPDQLQLFARFDPRRTPQFVRAAADLAVEIAG

Sequences:

>Translated_293_residues
MIKSRVTFKQLEAFVCVVDTGTFRKAAGILGTTQPNISTRIAALEDVLGTILMHRDAGSIRVTDKGAELLEAAREILRAG
ENFLEIAGRQDLIEDRLRLGVTELVACTWLHDFLRAFKDLYPAVRVELDVNLSTEIEKALITHQVDLALQTGPFARPVPG
TLPLGDYPYCWVAAPSLTPPASFAALFDGPVISHGRDTRASRALAEHARAEGVAVNQIVHSSSLTSCVAMAVDAMGPALL
PRLMVEDAIAQGRLSEFTCGWLPDQLQLFARFDPRRTPQFVRAAADLAVEIAG
>Mature_293_residues
MIKSRVTFKQLEAFVCVVDTGTFRKAAGILGTTQPNISTRIAALEDVLGTILMHRDAGSIRVTDKGAELLEAAREILRAG
ENFLEIAGRQDLIEDRLRLGVTELVACTWLHDFLRAFKDLYPAVRVELDVNLSTEIEKALITHQVDLALQTGPFARPVPG
TLPLGDYPYCWVAAPSLTPPASFAALFDGPVISHGRDTRASRALAEHARAEGVAVNQIVHSSSLTSCVAMAVDAMGPALL
PRLMVEDAIAQGRLSEFTCGWLPDQLQLFARFDPRRTPQFVRAAADLAVEIAG

Specific function: This protein is a positive regulator of gene expression of cephalosporinase (AmpC) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=157, Percent_Identity=28.0254777070064, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=25.7627118644068, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=29.4520547945205, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31812; Mature: 31812

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSRVTFKQLEAFVCVVDTGTFRKAAGILGTTQPNISTRIAALEDVLGTILMHRDAGSI
CCCCCHHHHHHHEEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCE
RVTDKGAELLEAAREILRAGENFLEIAGRQDLIEDRLRLGVTELVACTWLHDFLRAFKDL
EEECCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPAVRVELDVNLSTEIEKALITHQVDLALQTGPFARPVPGTLPLGDYPYCWVAAPSLTPP
CHHEEEEEECCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCC
ASFAALFDGPVISHGRDTRASRALAEHARAEGVAVNQIVHSSSLTSCVAMAVDAMGPALL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHH
PRLMVEDAIAQGRLSEFTCGWLPDQLQLFARFDPRRTPQFVRAAADLAVEIAG
HHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHEEEECC
>Mature Secondary Structure
MIKSRVTFKQLEAFVCVVDTGTFRKAAGILGTTQPNISTRIAALEDVLGTILMHRDAGSI
CCCCCHHHHHHHEEEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCE
RVTDKGAELLEAAREILRAGENFLEIAGRQDLIEDRLRLGVTELVACTWLHDFLRAFKDL
EEECCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPAVRVELDVNLSTEIEKALITHQVDLALQTGPFARPVPGTLPLGDYPYCWVAAPSLTPP
CHHEEEEEECCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCC
ASFAALFDGPVISHGRDTRASRALAEHARAEGVAVNQIVHSSSLTSCVAMAVDAMGPALL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHH
PRLMVEDAIAQGRLSEFTCGWLPDQLQLFARFDPRRTPQFVRAAADLAVEIAG
HHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2788410 [H]