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The map label for this gene is appB [H]

Identifier: 89056296

GI number: 89056296

Start: 3890896

End: 3891861

Strand: Direct

Name: appB [H]

Synonym: Jann_3805

Alternate gene names: 89056296

Gene position: 3890896-3891861 (Clockwise)

Preceding gene: 89056295

Following gene: 89056297

Centisome position: 90.11

GC content: 61.08

Gene sequence:

>966_bases
ATGAGCTATCTTCTAAGGCGCCTCGCGGTTTTTCCGCTGGTCATGCTGGGTGTGTCGATTTTTGTTTTCGTTGCAATCCG
ACTGGTGCCCGGCGACGCCATCACGGCGATGTTGGGCACCGAAGGCGGCATGCTGACGCCTGCTCAGCGGGAAGCGTTGA
CCGCCTATTTCGGCCTCGATCAGAATTGGGCCATTCAATATGTCCGCTGGCTTGGCGGGTTGTTTGGGGGCGATCTTGGG
ATCTCGGTCACTTACGGCCAACCGGTCCTCGACCTGATCCTGGAACGGTTTCCCCTGACGCTGCAACTGGCGCTGATGTC
GATGGTCATCGCCCTGCTGATCGGCCTGCCGGCAGGCGTCTTCGCCGCAACGCAAGCCAATCGCGCATCTGACCTGATCG
TCAGGATCTTCGCGATGATCGGCCAATCCATGCCCAATTTCGTGGTCGCGTTGCTGCTAATCTACGGCCTGTCGGTCGTT
TTCGGGGTCCTGCCGACGATGGGCCGGTACGTGCGGTTCACCGAAGACCCCCTCGGCAACTTGGCGCAGATGATCCTGCC
TGCCTTCGCCCTTGGCACAGCTTTCGCGGCAGCCGTGACGCGGATCACGCGCGCGGCGATGCTGGATATACTGAGCGAGG
ACTACGTGCGCACCGCGCGATCGCAGGGGTTTTCGCAAGCCTACGTCATCTGGCGCCACGCCTTACCGAATGCCCTGATC
CCGGTCCTGACGCTGAGCGGTGTGGAATTTGGCTACCTTCTGGGCGGCGCGGTCATCGTGGAGCAGATCTTTGCACTCCC
GGGCCTTGGCCGCGTGGTCCTGGACGCTATCGGAGAGAGGGACTACGCCCTTGTCCAAGGCGTTATCCTGTTCATCGCCT
TCAATTTCATGGTGGTTAACCTGCTGGTCGATCTGGCCTACGCCGCCCTTGATCCGCGCATTCGCTATGGCAGCGGCGGG
TCATGA

Upstream 100 bases:

>100_bases
ACCGACGCGGTCTCCGGATTCGTTCCCACGCCCAACGGATCGCTCTTCGGCCTCGTGGATGTGACCCTGGCTGAATAACA
AACGGCACGGGACACCCGGC

Downstream 100 bases:

>100_bases
CCCTCCTCCGCGCCCTTGCCCGCCACCCGGCAGGCCGCATCAGCCTTATCATCATCGGGTTGCTCAGCATCGCCGCGCTG
CTTGGGCTGTTTGGCCTGAC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSYLLRRLAVFPLVMLGVSIFVFVAIRLVPGDAITAMLGTEGGMLTPAQREALTAYFGLDQNWAIQYVRWLGGLFGGDLG
ISVTYGQPVLDLILERFPLTLQLALMSMVIALLIGLPAGVFAATQANRASDLIVRIFAMIGQSMPNFVVALLLIYGLSVV
FGVLPTMGRYVRFTEDPLGNLAQMILPAFALGTAFAAAVTRITRAAMLDILSEDYVRTARSQGFSQAYVIWRHALPNALI
PVLTLSGVEFGYLLGGAVIVEQIFALPGLGRVVLDAIGERDYALVQGVILFIAFNFMVVNLLVDLAYAALDPRIRYGSGG
S

Sequences:

>Translated_321_residues
MSYLLRRLAVFPLVMLGVSIFVFVAIRLVPGDAITAMLGTEGGMLTPAQREALTAYFGLDQNWAIQYVRWLGGLFGGDLG
ISVTYGQPVLDLILERFPLTLQLALMSMVIALLIGLPAGVFAATQANRASDLIVRIFAMIGQSMPNFVVALLLIYGLSVV
FGVLPTMGRYVRFTEDPLGNLAQMILPAFALGTAFAAAVTRITRAAMLDILSEDYVRTARSQGFSQAYVIWRHALPNALI
PVLTLSGVEFGYLLGGAVIVEQIFALPGLGRVVLDAIGERDYALVQGVILFIAFNFMVVNLLVDLAYAALDPRIRYGSGG
S
>Mature_320_residues
SYLLRRLAVFPLVMLGVSIFVFVAIRLVPGDAITAMLGTEGGMLTPAQREALTAYFGLDQNWAIQYVRWLGGLFGGDLGI
SVTYGQPVLDLILERFPLTLQLALMSMVIALLIGLPAGVFAATQANRASDLIVRIFAMIGQSMPNFVVALLLIYGLSVVF
GVLPTMGRYVRFTEDPLGNLAQMILPAFALGTAFAAAVTRITRAAMLDILSEDYVRTARSQGFSQAYVIWRHALPNALIP
VLTLSGVEFGYLLGGAVIVEQIFALPGLGRVVLDAIGERDYALVQGVILFIAFNFMVVNLLVDLAYAALDPRIRYGSGGS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=317, Percent_Identity=40.0630914826498, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=38.8235294117647, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789888, Length=321, Percent_Identity=38.3177570093458, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1787497, Length=318, Percent_Identity=34.2767295597484, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787761, Length=338, Percent_Identity=38.4615384615385, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=31.3432835820896, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788504, Length=288, Percent_Identity=28.125, Blast_Score=110, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34628; Mature: 34496

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLLRRLAVFPLVMLGVSIFVFVAIRLVPGDAITAMLGTEGGMLTPAQREALTAYFGLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
QNWAIQYVRWLGGLFGGDLGISVTYGQPVLDLILERFPLTLQLALMSMVIALLIGLPAGV
CHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHH
FAATQANRASDLIVRIFAMIGQSMPNFVVALLLIYGLSVVFGVLPTMGRYVRFTEDPLGN
HHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHH
LAQMILPAFALGTAFAAAVTRITRAAMLDILSEDYVRTARSQGFSQAYVIWRHALPNALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
PVLTLSGVEFGYLLGGAVIVEQIFALPGLGRVVLDAIGERDYALVQGVILFIAFNFMVVN
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LLVDLAYAALDPRIRYGSGGS
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SYLLRRLAVFPLVMLGVSIFVFVAIRLVPGDAITAMLGTEGGMLTPAQREALTAYFGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
QNWAIQYVRWLGGLFGGDLGISVTYGQPVLDLILERFPLTLQLALMSMVIALLIGLPAGV
CHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHH
FAATQANRASDLIVRIFAMIGQSMPNFVVALLLIYGLSVVFGVLPTMGRYVRFTEDPLGN
HHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHH
LAQMILPAFALGTAFAAAVTRITRAAMLDILSEDYVRTARSQGFSQAYVIWRHALPNALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHH
PVLTLSGVEFGYLLGGAVIVEQIFALPGLGRVVLDAIGERDYALVQGVILFIAFNFMVVN
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LLVDLAYAALDPRIRYGSGGS
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]