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The map label for this gene is qor [C]

Identifier: 89056084

GI number: 89056084

Start: 3669818

End: 3670834

Strand: Direct

Name: qor [C]

Synonym: Jann_3593

Alternate gene names: 89056084

Gene position: 3669818-3670834 (Clockwise)

Preceding gene: 89056080

Following gene: 89056085

Centisome position: 84.99

GC content: 65.19

Gene sequence:

>1017_bases
ATGGATAACCTGCCTGACACGATGCGCGCGCTGATGCTGCACGGGCCCGGAGACCGGCTGTCGCTGGAGGACGTGCCGCG
CCCCAAACCCGGTGCGGGAGAGGTTCTGGTGCGAATTGCGGCCTCCCCCATCAACCCGTCGGACCTTGCGATGTTGGCGG
GGGAATATGGGCTGCGCTGGCCCTATCCCCTGATCCCCGGGCTTGAAGGCTCCGGCGTTGTCTTGGGGGCAGGCAGTGGC
GTGATGGGCCGCGTCGTGATGGGAAAAAACGTGGCTTTGGTGGGCGAGAAACAGGGGCTTTGGGCTGACTACGCCGTGGT
GCCTGCAAGCCGCGTCCTGCCGCTGCCAAAGGACATGCCCCTGGGGGCCGGGGCCAGCAGCTTCGTGAACCCGCTGACCG
CCATCGCGCTTGTCGGCGAGGTGCGCCGGGCCAAGCAATGGTGCGCAATCTCCACCGCCGCCGGAGGGGCCCTGGGCGCG
ATGATCCGCAGGCGCGCGAAGGAGAAAGGCGTCAAGATCATCAACATCGGCCGCAAGCATGCGCAGGTGGAGGCGTTAAA
GGCCGAGGGCGCGCGGTTCGTGCTGGATGAGGCCGCCGCCGATTTCGACGCGGATCTGGCGGCGCTGTGCAAGGACCTGC
GGTGCCGGATGGCCTTTGACGCCGTTGGTGGGCAACTGACCTTCCGCGTGGGCCAGGCGTTGCGCAGCGGCGGACAGATT
CTTGTTTACGGCGGACTGTCGGGCGCACCGGCAAGCGTCCATCCCGGCACGATGATCTTCAAGGGTCTGACCGTGAAGGG
ATTCTGGCTGTCGCAATGGTTGGCCAAAAAGACCGCGCCGCAGATGTTGCTGATGACGCGCGAGGTCACGAAAGGTCTGC
AATCGGGCTTCGCGCAAACCCAGGTCGCGCGTCATGTTCCACTGGAATTGGCCGCAGACGCACCAGACGACTACGCCCGC
AACATGAGCGGTGGCAAGATCCTGATTTCCACCGGAGCTTACCCTTTGGGGCTATGA

Upstream 100 bases:

>100_bases
GCTGCATGGCGATCCTCCTTGGTCGCCTTCTGATATGGTCTGGGTTGCGGTTTGCCAAGGCGTCGGGGCCTGTGGCAGGC
TGACCGTGAAGGGAACGACA

Downstream 100 bases:

>100_bases
TCGCGGCGGCGGTGAGGCCCTCAAATCGCCAAAATCCCACGCTATGGCCTGAGGCACGACAGACATGACGCCACCTCCAA
CGCCTTCGTCCCAGGACATG

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MDNLPDTMRALMLHGPGDRLSLEDVPRPKPGAGEVLVRIAASPINPSDLAMLAGEYGLRWPYPLIPGLEGSGVVLGAGSG
VMGRVVMGKNVALVGEKQGLWADYAVVPASRVLPLPKDMPLGAGASSFVNPLTAIALVGEVRRAKQWCAISTAAGGALGA
MIRRRAKEKGVKIINIGRKHAQVEALKAEGARFVLDEAAADFDADLAALCKDLRCRMAFDAVGGQLTFRVGQALRSGGQI
LVYGGLSGAPASVHPGTMIFKGLTVKGFWLSQWLAKKTAPQMLLMTREVTKGLQSGFAQTQVARHVPLELAADAPDDYAR
NMSGGKILISTGAYPLGL

Sequences:

>Translated_338_residues
MDNLPDTMRALMLHGPGDRLSLEDVPRPKPGAGEVLVRIAASPINPSDLAMLAGEYGLRWPYPLIPGLEGSGVVLGAGSG
VMGRVVMGKNVALVGEKQGLWADYAVVPASRVLPLPKDMPLGAGASSFVNPLTAIALVGEVRRAKQWCAISTAAGGALGA
MIRRRAKEKGVKIINIGRKHAQVEALKAEGARFVLDEAAADFDADLAALCKDLRCRMAFDAVGGQLTFRVGQALRSGGQI
LVYGGLSGAPASVHPGTMIFKGLTVKGFWLSQWLAKKTAPQMLLMTREVTKGLQSGFAQTQVARHVPLELAADAPDDYAR
NMSGGKILISTGAYPLGL
>Mature_338_residues
MDNLPDTMRALMLHGPGDRLSLEDVPRPKPGAGEVLVRIAASPINPSDLAMLAGEYGLRWPYPLIPGLEGSGVVLGAGSG
VMGRVVMGKNVALVGEKQGLWADYAVVPASRVLPLPKDMPLGAGASSFVNPLTAIALVGEVRRAKQWCAISTAAGGALGA
MIRRRAKEKGVKIINIGRKHAQVEALKAEGARFVLDEAAADFDADLAALCKDLRCRMAFDAVGGQLTFRVGQALRSGGQI
LVYGGLSGAPASVHPGTMIFKGLTVKGFWLSQWLAKKTAPQMLLMTREVTKGLQSGFAQTQVARHVPLELAADAPDDYAR
NMSGGKILISTGAYPLGL

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA, NADH and crotonyl-CoA [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI67078404, Length=314, Percent_Identity=28.6624203821656, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI67078406, Length=275, Percent_Identity=29.0909090909091, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI28557745, Length=309, Percent_Identity=26.2135922330097, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI22538446, Length=306, Percent_Identity=24.1830065359477, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI22538444, Length=306, Percent_Identity=24.1830065359477, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI18379349, Length=359, Percent_Identity=24.7910863509749, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI24308257, Length=218, Percent_Identity=27.0642201834862, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=26.9113149847095, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17556000, Length=276, Percent_Identity=32.6086956521739, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17536829, Length=291, Percent_Identity=28.1786941580756, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988145, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319500, Length=292, Percent_Identity=27.7397260273973, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319520, Length=255, Percent_Identity=25.8823529411765, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550423, Length=293, Percent_Identity=30.3754266211604, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 35498; Mature: 35498

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLPDTMRALMLHGPGDRLSLEDVPRPKPGAGEVLVRIAASPINPSDLAMLAGEYGLRW
CCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCC
PYPLIPGLEGSGVVLGAGSGVMGRVVMGKNVALVGEKQGLWADYAVVPASRVLPLPKDMP
CCCCCCCCCCCCEEEECCCCCEEEEEECCCEEEEECCCCCEECEEECCHHHCCCCCCCCC
LGAGASSFVNPLTAIALVGEVRRAKQWCAISTAAGGALGAMIRRRAKEKGVKIINIGRKH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCEEEEECCHH
AQVEALKAEGARFVLDEAAADFDADLAALCKDLRCRMAFDAVGGQLTFRVGQALRSGGQI
HHHHHHHHCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCEE
LVYGGLSGAPASVHPGTMIFKGLTVKGFWLSQWLAKKTAPQMLLMTREVTKGLQSGFAQT
EEEECCCCCCCCCCCCCEEEECCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHH
QVARHVPLELAADAPDDYARNMSGGKILISTGAYPLGL
HHHHCCCEEEECCCCHHHHHCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MDNLPDTMRALMLHGPGDRLSLEDVPRPKPGAGEVLVRIAASPINPSDLAMLAGEYGLRW
CCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCC
PYPLIPGLEGSGVVLGAGSGVMGRVVMGKNVALVGEKQGLWADYAVVPASRVLPLPKDMP
CCCCCCCCCCCCEEEECCCCCEEEEEECCCEEEEECCCCCEECEEECCHHHCCCCCCCCC
LGAGASSFVNPLTAIALVGEVRRAKQWCAISTAAGGALGAMIRRRAKEKGVKIINIGRKH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCEEEEECCHH
AQVEALKAEGARFVLDEAAADFDADLAALCKDLRCRMAFDAVGGQLTFRVGQALRSGGQI
HHHHHHHHCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCEE
LVYGGLSGAPASVHPGTMIFKGLTVKGFWLSQWLAKKTAPQMLLMTREVTKGLQSGFAQT
EEEECCCCCCCCCCCCCEEEECCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHH
QVARHVPLELAADAPDDYARNMSGGKILISTGAYPLGL
HHHHCCCEEEECCCCHHHHHCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]