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The map label for this gene is trpB [H]

Identifier: 89056080

GI number: 89056080

Start: 3666152

End: 3667381

Strand: Direct

Name: trpB [H]

Synonym: Jann_3589

Alternate gene names: 89056080

Gene position: 3666152-3667381 (Clockwise)

Preceding gene: 89056079

Following gene: 89056084

Centisome position: 84.9

GC content: 62.44

Gene sequence:

>1230_bases
ATGCCAGACGATCTATTGAACAGCTTCATGACGGGACCCGATGAAAAGGGCCGGTTCGGTGATTTCGGCGGGCGGTTTGT
GTCGGAGACGCTGATGCCGCTGATCCTTGAGCTGGAGCAGCAATATGAGCACGCAAAGACCGACGACAGCTTCTGGGCCG
AGATGCAGGACCTCTGGACCCATTATGTGGGTCGCCCCTCTCCGCTCTATTTCGCGAAACGTCTGACCGAGCGTCTGGGC
GGCGCGAAGATCTACCTCAAACGCGATGAGCTGAACCACACGGGCGCCCACAAGATCAACAACGTGTTGGGCCAGATCAT
CCTGGCGCGGCGCATGGGCAAGACCCGCATTATTGCTGAGACAGGAGCGGGCCAGCACGGCGTGGCCACCGCCACGGTCT
GCGCGAAGTTTGGCCTCAAATGCATCGTCTACATGGGCGCGACGGATGTGGAGCGTCAGGCCCCCAACGTGTTCCGCATG
AAGCTTCTGGGCGCGGAGGTCGTACCGGTGACCTCCGGGCGCGGCACACTCAAGGACGCGATGAACGACGCCCTGCGCGA
CTGGGTCACCAACGTGCGCGATACCTTCTACTGCATCGGCACGGTCGCAGGTCCCCACCCCTACCCCGCCATGGTCCGCG
ATTTTCAGGCGATCATCGGCAAGGAGACACGCGACCAGATGATGGCCGCAGAAGGCCGCCTGCCCGATACGCTGATCGCC
GCCATCGGCGGTGGCTCCAACGCCATGGGCCTGTTCTTCCCATTCCTGGACGACAAGAGTGTGAACATCATCGGGGTGGA
GGCCGGCGGCCACGGCGTCAATGAGAAGATGGAACATTGTGCATCCCTGACCGGGGGTCGCCCCGGCGTGCTGCACGGCA
ATCGGACGTATCTGTTGCAGGATGAGGATGGACAGATCCTTGAAGGGCATTCGATCTCGGCCGGTCTGGATTATCCCGGG
ATCGGACCGGAGCACGCCTGGCTGCACGAGATCGGGCGCGCGCAATATGTCTCCATCACGGATCGGGAAGCGTTGGACGC
CTTCCAGCTGTCATGCGAGACTGAGGGTATCATCCCGGCGCTGGAACCGTCCCACGCGCTGGCCCACGTGTGCAAGATTG
CGCCCGATATGCCCCGCGATCATCTGCTGGTGATGAACATGTGCGGACGCGGCGACAAGGATATCTTCACCGTCGCCCGG
GCCCTCGGCTGGGATATGGACGGGGCCTGA

Upstream 100 bases:

>100_bases
GTTTGAAAACCGCGTGCGTCAAGGCCTTTCGAAAGGCCTTCCCCTTGCCCCGCCCACATCCGCGCGCTACCCCTCCACCC
GTCGCAAGGGGGAGATCACG

Downstream 100 bases:

>100_bases
GGAACCTGCCGGGAGACACCCGGCGTGCCTACGGGCAAAGTGGCTGAATGGCTCCGGTTGCAAGGTTGCAACCGGGGGCT
ATACCCCTGATAATAAAGGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPDDLLNSFMTGPDEKGRFGDFGGRFVSETLMPLILELEQQYEHAKTDDSFWAEMQDLWTHYVGRPSPLYFAKRLTERLG
GAKIYLKRDELNHTGAHKINNVLGQIILARRMGKTRIIAETGAGQHGVATATVCAKFGLKCIVYMGATDVERQAPNVFRM
KLLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQAIIGKETRDQMMAAEGRLPDTLIA
AIGGGSNAMGLFFPFLDDKSVNIIGVEAGGHGVNEKMEHCASLTGGRPGVLHGNRTYLLQDEDGQILEGHSISAGLDYPG
IGPEHAWLHEIGRAQYVSITDREALDAFQLSCETEGIIPALEPSHALAHVCKIAPDMPRDHLLVMNMCGRGDKDIFTVAR
ALGWDMDGA

Sequences:

>Translated_409_residues
MPDDLLNSFMTGPDEKGRFGDFGGRFVSETLMPLILELEQQYEHAKTDDSFWAEMQDLWTHYVGRPSPLYFAKRLTERLG
GAKIYLKRDELNHTGAHKINNVLGQIILARRMGKTRIIAETGAGQHGVATATVCAKFGLKCIVYMGATDVERQAPNVFRM
KLLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQAIIGKETRDQMMAAEGRLPDTLIA
AIGGGSNAMGLFFPFLDDKSVNIIGVEAGGHGVNEKMEHCASLTGGRPGVLHGNRTYLLQDEDGQILEGHSISAGLDYPG
IGPEHAWLHEIGRAQYVSITDREALDAFQLSCETEGIIPALEPSHALAHVCKIAPDMPRDHLLVMNMCGRGDKDIFTVAR
ALGWDMDGA
>Mature_408_residues
PDDLLNSFMTGPDEKGRFGDFGGRFVSETLMPLILELEQQYEHAKTDDSFWAEMQDLWTHYVGRPSPLYFAKRLTERLGG
AKIYLKRDELNHTGAHKINNVLGQIILARRMGKTRIIAETGAGQHGVATATVCAKFGLKCIVYMGATDVERQAPNVFRMK
LLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQAIIGKETRDQMMAAEGRLPDTLIAA
IGGGSNAMGLFFPFLDDKSVNIIGVEAGGHGVNEKMEHCASLTGGRPGVLHGNRTYLLQDEDGQILEGHSISAGLDYPGI
GPEHAWLHEIGRAQYVSITDREALDAFQLSCETEGIIPALEPSHALAHVCKIAPDMPRDHLLVMNMCGRGDKDIFTVARA
LGWDMDGA

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=57.2178477690289, Blast_Score=444, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321412, Length=411, Percent_Identity=54.9878345498783, Blast_Score=476, Evalue=1e-135,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44752; Mature: 44621

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDDLLNSFMTGPDEKGRFGDFGGRFVSETLMPLILELEQQYEHAKTDDSFWAEMQDLWT
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HYVGRPSPLYFAKRLTERLGGAKIYLKRDELNHTGAHKINNVLGQIILARRMGKTRIIAE
HHCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
TGAGQHGVATATVCAKFGLKCIVYMGATDVERQAPNVFRMKLLGAEVVPVTSGRGTLKDA
CCCCCCCHHHHHHHHHHCCEEEEEECCCCHHHHCCCCEEHHHHCCEEEEECCCCCHHHHH
MNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQAIIGKETRDQMMAAEGRLPDTLIA
HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHE
AIGGGSNAMGLFFPFLDDKSVNIIGVEAGGHGVNEKMEHCASLTGGRPGVLHGNRTYLLQ
EECCCCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCEEEEEE
DEDGQILEGHSISAGLDYPGIGPEHAWLHEIGRAQYVSITDREALDAFQLSCETEGIIPA
CCCCCEECCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCCC
LEPSHALAHVCKIAPDMPRDHLLVMNMCGRGDKDIFTVARALGWDMDGA
CCCHHHHHHHHHHCCCCCCCCEEEEHHCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PDDLLNSFMTGPDEKGRFGDFGGRFVSETLMPLILELEQQYEHAKTDDSFWAEMQDLWT
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HYVGRPSPLYFAKRLTERLGGAKIYLKRDELNHTGAHKINNVLGQIILARRMGKTRIIAE
HHCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
TGAGQHGVATATVCAKFGLKCIVYMGATDVERQAPNVFRMKLLGAEVVPVTSGRGTLKDA
CCCCCCCHHHHHHHHHHCCEEEEEECCCCHHHHCCCCEEHHHHCCEEEEECCCCCHHHHH
MNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQAIIGKETRDQMMAAEGRLPDTLIA
HHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHE
AIGGGSNAMGLFFPFLDDKSVNIIGVEAGGHGVNEKMEHCASLTGGRPGVLHGNRTYLLQ
EECCCCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCEEEEEE
DEDGQILEGHSISAGLDYPGIGPEHAWLHEIGRAQYVSITDREALDAFQLSCETEGIIPA
CCCCCEECCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCCC
LEPSHALAHVCKIAPDMPRDHLLVMNMCGRGDKDIFTVARALGWDMDGA
CCCHHHHHHHHHHCCCCCCCCEEEEHHCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA