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The map label for this gene is gpwA [H]

Identifier: 89055764

GI number: 89055764

Start: 3327052

End: 3327576

Strand: Direct

Name: gpwA [H]

Synonym: Jann_3273

Alternate gene names: 89055764

Gene position: 3327052-3327576 (Clockwise)

Preceding gene: 89055761

Following gene: 89055765

Centisome position: 77.05

GC content: 65.14

Gene sequence:

>525_bases
ATGGACCGTCGCCTGTTTCTGAGTGCCACCGCCGCGTGCCTTGCCCTGGGCCCGGCGCGGGCCACGCAAGCCTTCAGCTT
TCCATCCATTGATGGGGGCACCTACGATTTGCTCGCCTGGCGGGGGCAACCGCTGTTGGTGGTCAACACCGCCTCGCTCT
GCGGGTTCACGGGCCAGTACGATGGATTGCAAAGGGTGCATGAGGCCTATGCGGGCCGCGCCCGTGTTTTGGCAGTGCCG
TCAGATGATTTCGCCCAGGAATTGGGCAGCGAGGCGGAGGTGGCCGCGTTTTGTGAGGTCAATTTCGGGCTGACCCTGCC
GATGACCACGATCCAACCCGTGCGCGGACCCCGGGCGCATCCGTTCTATCGCTGGCTCGCCACCGCCCATCGCTTCACCC
CGCAATGGAATTTCAACAAGGTGCTGCTGGACGCAGACGGCGCATTGGTGGCCACCTGGGGGTCGCGCCCCGAGCCCATG
GGTCGCCGTATCCGCAGCGCGATTGACGGGCTTCTCTCTGCGTGA

Upstream 100 bases:

>100_bases
CCTGATTACATGGGGCGCAGCGCGACGCAATCACACCACCCGCACCGCCCGTTGAATTGTTGCGTTTTCGCGATAGGTCT
GAGGATAGAAAGGAGCCGCC

Downstream 100 bases:

>100_bases
GGCCGCTGTTTTTGGGCTCCGAGATTTACCGTGGGTCCAGCTACGGGCGCTGGCATCCGCTGCGGGTGCCCCGGGTGTCT
ACGGTCATGGATTTGAGCCG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MDRRLFLSATAACLALGPARATQAFSFPSIDGGTYDLLAWRGQPLLVVNTASLCGFTGQYDGLQRVHEAYAGRARVLAVP
SDDFAQELGSEAEVAAFCEVNFGLTLPMTTIQPVRGPRAHPFYRWLATAHRFTPQWNFNKVLLDADGALVATWGSRPEPM
GRRIRSAIDGLLSA

Sequences:

>Translated_174_residues
MDRRLFLSATAACLALGPARATQAFSFPSIDGGTYDLLAWRGQPLLVVNTASLCGFTGQYDGLQRVHEAYAGRARVLAVP
SDDFAQELGSEAEVAAFCEVNFGLTLPMTTIQPVRGPRAHPFYRWLATAHRFTPQWNFNKVLLDADGALVATWGSRPEPM
GRRIRSAIDGLLSA
>Mature_174_residues
MDRRLFLSATAACLALGPARATQAFSFPSIDGGTYDLLAWRGQPLLVVNTASLCGFTGQYDGLQRVHEAYAGRARVLAVP
SDDFAQELGSEAEVAAFCEVNFGLTLPMTTIQPVRGPRAHPFYRWLATAHRFTPQWNFNKVLLDADGALVATWGSRPEPM
GRRIRSAIDGLLSA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI192455698, Length=152, Percent_Identity=32.8947368421053, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI15618997, Length=151, Percent_Identity=35.0993377483444, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI75709200, Length=151, Percent_Identity=33.112582781457, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI90903240, Length=151, Percent_Identity=33.112582781457, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1788003, Length=148, Percent_Identity=32.4324324324324, Blast_Score=76, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319721, Length=146, Percent_Identity=32.1917808219178, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322228, Length=140, Percent_Identity=32.1428571428571, Blast_Score=85, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322826, Length=147, Percent_Identity=29.2517006802721, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18941; Mature: 18941

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRLFLSATAACLALGPARATQAFSFPSIDGGTYDLLAWRGQPLLVVNTASLCGFTGQY
CCCEEEHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECHHHHCCCCCC
DGLQRVHEAYAGRARVLAVPSDDFAQELGSEAEVAAFCEVNFGLTLPMTTIQPVRGPRAH
HHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEECCCEECCCCCCCCCCCCCCC
PFYRWLATAHRFTPQWNFNKVLLDADGALVATWGSRPEPMGRRIRSAIDGLLSA
HHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRRLFLSATAACLALGPARATQAFSFPSIDGGTYDLLAWRGQPLLVVNTASLCGFTGQY
CCCEEEHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECHHHHCCCCCC
DGLQRVHEAYAGRARVLAVPSDDFAQELGSEAEVAAFCEVNFGLTLPMTTIQPVRGPRAH
HHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEECCCEECCCCCCCCCCCCCCC
PFYRWLATAHRFTPQWNFNKVLLDADGALVATWGSRPEPMGRRIRSAIDGLLSA
HHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA