Click here to switch to the map view.

The map label for this gene is acuC [H]

Identifier: 89055765

GI number: 89055765

Start: 3327573

End: 3328700

Strand: Direct

Name: acuC [H]

Synonym: Jann_3274

Alternate gene names: 89055765

Gene position: 3327573-3328700 (Clockwise)

Preceding gene: 89055764

Following gene: 89055766

Centisome position: 77.06

GC content: 68.26

Gene sequence:

>1128_bases
GTGAGGCCGCTGTTTTTGGGCTCCGAGATTTACCGTGGGTCCAGCTACGGGCGCTGGCATCCGCTGCGGGTGCCCCGGGT
GTCTACGGTCATGGATTTGAGCCGTGCGATGGGCTGGTTGGGGCCGGGCCAATACCGCAACTCGCCCCGCGCCAAGCCCG
CCGCCCTGCATGTCTGGCACACGCCCGCGTATATTGCGGCGCTGCAACAGGCCGAAGCTGATCAAGCCGTGACGGATGCG
GTGCGCGACCGCCACGGGCTCGGCACCGTCTCCAACCCGATCTATCCGGAAATGTTTCGCCGCCCCGCCACGGCGGCGGG
CGCGTCGCTGCTGGCCGGAGAGCTGTTGAAAGACGGTGGCGTGATCTATCACCCGGGCGGCGGCACGCATCACGGGATGC
GCGACCGGGCGGGCGGGTTTTGCTACCTCAACGACCCGGTCCTCGCCATGCTGTCGCTGCGCCGCAATGGCGCGCGGCGG
ATCGCCTACGTGGATATCGACGCCCACCATTGCGACGGCGTGGAAGACGCGTTTGCGGGCGATCCCGACACGCTCCTGAT
CTCCGTCCATGAGGAAAAGCGCTGGCCGTTCACCGGGGCTCTGGAAGATGACGGTGCAACGCCGGGGGGCGTGGCCAATT
GCCTGAACCTGCCGGTGCCACGCGACTTCAATGACAGCGAAATGGCCGCGATCCGCGACGATCTGATTCTGCCATTTGTC
GCGCGGTTCCGGCCCGATGCCGTCGTGCTGCAATGCGGGGCCGATGCGGTGACGGAAGACCCACTAAGTCGCCTGACCCT
GTCAAACAACGCTCATTGGGCAATTTTGCGCGGGCTGATGGACCTGCACCCGCCGCGCCTGCTGGTCCTGGGCGGTGGCG
GCTACAACCCGTGGTCCGTCGGGCGGTTGTGGACCGGGATCTGGGCGACGTTGAACAGGCATCCCATCCCGGATCGGGTC
CCGGCGCCGGCGGAAGATGTGCTCCGCGCGCTCAGGTGGGACGGCGCGCGCGCGGGGCGCAATCCGCCCGATCACTGGTT
CACCACCCTGCGCGATGCACCCCGCCCCGGCCCGGTGCGGCCAGAGGTGGCCCGGCGCGTGCGGCATCTGGCCCATCGGC
GGATCTGA

Upstream 100 bases:

>100_bases
TGCTGCTGGACGCAGACGGCGCATTGGTGGCCACCTGGGGGTCGCGCCCCGAGCCCATGGGTCGCCGTATCCGCAGCGCG
ATTGACGGGCTTCTCTCTGC

Downstream 100 bases:

>100_bases
GTAAAATACTCAGGATTGACATGGCATACTATTTTAGTCAGGTTTACATCATCACCCCGATCCAAAGGGAATCCGGACAT
GACCTACCAGGCCAGAATGA

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRPLFLGSEIYRGSSYGRWHPLRVPRVSTVMDLSRAMGWLGPGQYRNSPRAKPAALHVWHTPAYIAALQQAEADQAVTDA
VRDRHGLGTVSNPIYPEMFRRPATAAGASLLAGELLKDGGVIYHPGGGTHHGMRDRAGGFCYLNDPVLAMLSLRRNGARR
IAYVDIDAHHCDGVEDAFAGDPDTLLISVHEEKRWPFTGALEDDGATPGGVANCLNLPVPRDFNDSEMAAIRDDLILPFV
ARFRPDAVVLQCGADAVTEDPLSRLTLSNNAHWAILRGLMDLHPPRLLVLGGGGYNPWSVGRLWTGIWATLNRHPIPDRV
PAPAEDVLRALRWDGARAGRNPPDHWFTTLRDAPRPGPVRPEVARRVRHLAHRRI

Sequences:

>Translated_375_residues
MRPLFLGSEIYRGSSYGRWHPLRVPRVSTVMDLSRAMGWLGPGQYRNSPRAKPAALHVWHTPAYIAALQQAEADQAVTDA
VRDRHGLGTVSNPIYPEMFRRPATAAGASLLAGELLKDGGVIYHPGGGTHHGMRDRAGGFCYLNDPVLAMLSLRRNGARR
IAYVDIDAHHCDGVEDAFAGDPDTLLISVHEEKRWPFTGALEDDGATPGGVANCLNLPVPRDFNDSEMAAIRDDLILPFV
ARFRPDAVVLQCGADAVTEDPLSRLTLSNNAHWAILRGLMDLHPPRLLVLGGGGYNPWSVGRLWTGIWATLNRHPIPDRV
PAPAEDVLRALRWDGARAGRNPPDHWFTTLRDAPRPGPVRPEVARRVRHLAHRRI
>Mature_375_residues
MRPLFLGSEIYRGSSYGRWHPLRVPRVSTVMDLSRAMGWLGPGQYRNSPRAKPAALHVWHTPAYIAALQQAEADQAVTDA
VRDRHGLGTVSNPIYPEMFRRPATAAGASLLAGELLKDGGVIYHPGGGTHHGMRDRAGGFCYLNDPVLAMLSLRRNGARR
IAYVDIDAHHCDGVEDAFAGDPDTLLISVHEEKRWPFTGALEDDGATPGGVANCLNLPVPRDFNDSEMAAIRDDLILPFV
ARFRPDAVVLQCGADAVTEDPLSRLTLSNNAHWAILRGLMDLHPPRLLVLGGGGYNPWSVGRLWTGIWATLNRHPIPDRV
PAPAEDVLRALRWDGARAGRNPPDHWFTTLRDAPRPGPVRPEVARRVRHLAHRRI

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI8923769, Length=306, Percent_Identity=32.6797385620915, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI13128860, Length=310, Percent_Identity=30.3225806451613, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI13128862, Length=312, Percent_Identity=30.7692307692308, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI262073088, Length=194, Percent_Identity=36.0824742268041, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI293336691, Length=310, Percent_Identity=30.3225806451613, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI262073092, Length=216, Percent_Identity=34.7222222222222, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI13128864, Length=300, Percent_Identity=28.3333333333333, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI20070354, Length=355, Percent_Identity=25.6338028169014, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI153085395, Length=261, Percent_Identity=29.1187739463602, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI30795204, Length=228, Percent_Identity=29.3859649122807, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI30795202, Length=228, Percent_Identity=29.3859649122807, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI17158039, Length=228, Percent_Identity=29.3859649122807, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI148539870, Length=231, Percent_Identity=29.004329004329, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI169234807, Length=217, Percent_Identity=29.9539170506912, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI62750349, Length=229, Percent_Identity=30.1310043668122, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI62750347, Length=229, Percent_Identity=30.1310043668122, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI226529806, Length=354, Percent_Identity=25.7062146892655, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17534739, Length=338, Percent_Identity=31.0650887573964, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17508561, Length=311, Percent_Identity=32.7974276527331, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17561978, Length=315, Percent_Identity=31.7460317460317, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17540334, Length=320, Percent_Identity=24.0625, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193206283, Length=320, Percent_Identity=24.0625, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540332, Length=320, Percent_Identity=24.0625, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537347, Length=287, Percent_Identity=25.0871080139373, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193209491, Length=225, Percent_Identity=27.1111111111111, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321244, Length=323, Percent_Identity=30.3405572755418, Blast_Score=139, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6323999, Length=314, Percent_Identity=29.9363057324841, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6325325, Length=182, Percent_Identity=35.7142857142857, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6324307, Length=233, Percent_Identity=27.8969957081545, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644244, Length=315, Percent_Identity=30.4761904761905, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24657891, Length=294, Percent_Identity=31.2925170068027, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360899, Length=313, Percent_Identity=26.517571884984, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24642144, Length=313, Percent_Identity=26.517571884984, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24642146, Length=313, Percent_Identity=26.517571884984, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24642142, Length=313, Percent_Identity=26.517571884984, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641720, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281360799, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281360801, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 41314; Mature: 41314

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLFLGSEIYRGSSYGRWHPLRVPRVSTVMDLSRAMGWLGPGQYRNSPRAKPAALHVWH
CCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC
TPAYIAALQQAEADQAVTDAVRDRHGLGTVSNPIYPEMFRRPATAAGASLLAGELLKDGG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCC
VIYHPGGGTHHGMRDRAGGFCYLNDPVLAMLSLRRNGARRIAYVDIDAHHCDGVEDAFAG
EEECCCCCCCCCCHHCCCCEEEECCHHHHHHHHHCCCCCEEEEEEECCHHCCCCHHHHCC
DPDTLLISVHEEKRWPFTGALEDDGATPGGVANCLNLPVPRDFNDSEMAAIRDDLILPFV
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
ARFRPDAVVLQCGADAVTEDPLSRLTLSNNAHWAILRGLMDLHPPRLLVLGGGGYNPWSV
HHCCCCEEEEECCCCHHHHCCHHHEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHH
GRLWTGIWATLNRHPIPDRVPAPAEDVLRALRWDGARAGRNPPDHWFTTLRDAPRPGPVR
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCC
PEVARRVRHLAHRRI
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MRPLFLGSEIYRGSSYGRWHPLRVPRVSTVMDLSRAMGWLGPGQYRNSPRAKPAALHVWH
CCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC
TPAYIAALQQAEADQAVTDAVRDRHGLGTVSNPIYPEMFRRPATAAGASLLAGELLKDGG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCC
VIYHPGGGTHHGMRDRAGGFCYLNDPVLAMLSLRRNGARRIAYVDIDAHHCDGVEDAFAG
EEECCCCCCCCCCHHCCCCEEEECCHHHHHHHHHCCCCCEEEEEEECCHHCCCCHHHHCC
DPDTLLISVHEEKRWPFTGALEDDGATPGGVANCLNLPVPRDFNDSEMAAIRDDLILPFV
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
ARFRPDAVVLQCGADAVTEDPLSRLTLSNNAHWAILRGLMDLHPPRLLVLGGGGYNPWSV
HHCCCCEEEEECCCCHHHHCCHHHEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHH
GRLWTGIWATLNRHPIPDRVPAPAEDVLRALRWDGARAGRNPPDHWFTTLRDAPRPGPVR
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCC
PEVARRVRHLAHRRI
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]