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The map label for this gene is rbsK [H]

Identifier: 89055581

GI number: 89055581

Start: 3125150

End: 3126079

Strand: Direct

Name: rbsK [H]

Synonym: Jann_3090

Alternate gene names: 89055581

Gene position: 3125150-3126079 (Clockwise)

Preceding gene: 89055580

Following gene: 89055582

Centisome position: 72.38

GC content: 61.72

Gene sequence:

>930_bases
GTGACCTACATTTGTGTCGTTGGCAGCATCAATGTTGATCTCACCTGTTATCTGCCGCGCTGGCCTGATCGCGGCGAAAC
GATCTCGGCCTTGAGGACCCAGACCGGGCTTGGGGGCAAAGGCGCCAACCAGGCCGTGGCCGCCAGAAGACTTGGCGCTA
ACGTCCATCTGATCGGCGCGATCGGCGCGGACCCATTCGGGGCAGATTGCGCCCTCGCACTTCGCCAAGCCGACATCACA
CCGCACCTGATGGAAGCCACAAAAACGGCCACCGGCATGGCGCTGATTGATGTGGGACCGTCAGGGGACAATATCATTCG
CCTGGCCCACGGTGCGAATTATGATCTGGACCTTGCGTTTCTGGATCAACACCGCGCTGTGATCGAAGGCTGTGCTGTGC
TGCTTCTTCAAAATGAAATTCCAGTTGAGATCTCAATTGCTGCGGCCCAACTGGCCAAGGCTGCGGGCGCTTTGGTGATC
ATGGATCCCGCCCCTGCCCCATCTGCCCCCTGGGGACCGGATGTCTTGCACCATTTCGATGTCATAACGCCCAATACCCA
TGAAGCCGGCCTGCTTCTGGGATCGACGCCCCGCACACTTGCGGATGCACGGGTCGCCGCAGCGAACTTGGCCACGATGG
GACCAACCGGCGCGATTGTGACAATGGGTGGCGATGGTGTCGCCTGGCATGTCGGGGCGGACAGCGGGCAAATGCTGCCG
CCGGAGACAGCCGTCATTGATACGGTCGGCGCCGGGGACTGCTTCAATGGTGCGCTTGCGGCCTATCTGGCCAAGACCCA
AACCATCTCAGTCGCCATCACCGCTGCCTGCGCGGCGGCCAGCCTGTCAACACGCCGGGCGGGTGCCGCGGCGTCGCTTC
CGACCTTGCAGGAGGTACAGAACCTTCTTGACGGGCTGGCAGTTGCTTGA

Upstream 100 bases:

>100_bases
CCAATACCGCGCAGCCTTGCTTTGCGGGCGGCCGGGTGATCATCCGCACCGCAAAGTGCATGCCCAGCCCCAATCTTGTC
CCGGCCAGCGGGGTGCCCTT

Downstream 100 bases:

>100_bases
TTGATCCAGTCGAAACTGCGAGGTGGCCTTAACACCACGTCCTCCCCTGACTTTTTTGGAAACCGGATGCCGACAGTCAA
AGATGTAGCCCGTCACGCTG

Product: PfkB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTYICVVGSINVDLTCYLPRWPDRGETISALRTQTGLGGKGANQAVAARRLGANVHLIGAIGADPFGADCALALRQADIT
PHLMEATKTATGMALIDVGPSGDNIIRLAHGANYDLDLAFLDQHRAVIEGCAVLLLQNEIPVEISIAAAQLAKAAGALVI
MDPAPAPSAPWGPDVLHHFDVITPNTHEAGLLLGSTPRTLADARVAAANLATMGPTGAIVTMGGDGVAWHVGADSGQMLP
PETAVIDTVGAGDCFNGALAAYLAKTQTISVAITAACAAASLSTRRAGAAASLPTLQEVQNLLDGLAVA

Sequences:

>Translated_309_residues
MTYICVVGSINVDLTCYLPRWPDRGETISALRTQTGLGGKGANQAVAARRLGANVHLIGAIGADPFGADCALALRQADIT
PHLMEATKTATGMALIDVGPSGDNIIRLAHGANYDLDLAFLDQHRAVIEGCAVLLLQNEIPVEISIAAAQLAKAAGALVI
MDPAPAPSAPWGPDVLHHFDVITPNTHEAGLLLGSTPRTLADARVAAANLATMGPTGAIVTMGGDGVAWHVGADSGQMLP
PETAVIDTVGAGDCFNGALAAYLAKTQTISVAITAACAAASLSTRRAGAAASLPTLQEVQNLLDGLAVA
>Mature_308_residues
TYICVVGSINVDLTCYLPRWPDRGETISALRTQTGLGGKGANQAVAARRLGANVHLIGAIGADPFGADCALALRQADITP
HLMEATKTATGMALIDVGPSGDNIIRLAHGANYDLDLAFLDQHRAVIEGCAVLLLQNEIPVEISIAAAQLAKAAGALVIM
DPAPAPSAPWGPDVLHHFDVITPNTHEAGLLLGSTPRTLADARVAAANLATMGPTGAIVTMGGDGVAWHVGADSGQMLPP
ETAVIDTVGAGDCFNGALAAYLAKTQTISVAITAACAAASLSTRRAGAAASLPTLQEVQNLLDGLAVA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=36.7003367003367, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=38.8157894736842, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788491, Length=298, Percent_Identity=25.503355704698, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=36.963696369637, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319884, Length=334, Percent_Identity=30.5389221556886, Blast_Score=108, Evalue=8e-25,
Organism=Drosophila melanogaster, GI20128807, Length=309, Percent_Identity=36.2459546925566, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24583886, Length=302, Percent_Identity=31.1258278145695, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31386; Mature: 31255

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYICVVGSINVDLTCYLPRWPDRGETISALRTQTGLGGKGANQAVAARRLGANVHLIGA
CEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEEE
IGADPFGADCALALRQADITPHLMEATKTATGMALIDVGPSGDNIIRLAHGANYDLDLAF
ECCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCEEEEE
LDQHRAVIEGCAVLLLQNEIPVEISIAAAQLAKAAGALVIMDPAPAPSAPWGPDVLHHFD
HHHHHHHHHHHEEEEECCCCCEEEEHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHEE
VITPNTHEAGLLLGSTPRTLADARVAAANLATMGPTGAIVTMGGDGVAWHVGADSGQMLP
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHEECCCCCEEEEECCCCEEEEEECCCCCCCC
PETAVIDTVGAGDCFNGALAAYLAKTQTISVAITAACAAASLSTRRAGAAASLPTLQEVQ
CCCEEEECCCCCCHHHHHHHHHHHHCEEEEEEEEEHHHHHHHHHHCCCCCCCCCCHHHHH
NLLDGLAVA
HHHHHHCCC
>Mature Secondary Structure 
TYICVVGSINVDLTCYLPRWPDRGETISALRTQTGLGGKGANQAVAARRLGANVHLIGA
EEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEEE
IGADPFGADCALALRQADITPHLMEATKTATGMALIDVGPSGDNIIRLAHGANYDLDLAF
ECCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCEEEEE
LDQHRAVIEGCAVLLLQNEIPVEISIAAAQLAKAAGALVIMDPAPAPSAPWGPDVLHHFD
HHHHHHHHHHHEEEEECCCCCEEEEHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHEE
VITPNTHEAGLLLGSTPRTLADARVAAANLATMGPTGAIVTMGGDGVAWHVGADSGQMLP
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHEECCCCCEEEEECCCCEEEEEECCCCCCCC
PETAVIDTVGAGDCFNGALAAYLAKTQTISVAITAACAAASLSTRRAGAAASLPTLQEVQ
CCCEEEECCCCCCHHHHHHHHHHHHCEEEEEEEEEHHHHHHHHHHCCCCCCCCCCHHHHH
NLLDGLAVA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]