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The map label for this gene is est [H]

Identifier: 89055157

GI number: 89055157

Start: 2676580

End: 2677461

Strand: Direct

Name: est [H]

Synonym: Jann_2666

Alternate gene names: 89055157

Gene position: 2676580-2677461 (Clockwise)

Preceding gene: 89055156

Following gene: 89055158

Centisome position: 61.99

GC content: 65.53

Gene sequence:

>882_bases
ATGAGCGTGCTGACCCGCGCCGACCGAATCTCGACGTGGACTGCGCGCCGCATCGAGAAACCGCTGCTGTCCATGATCGG
CTCGCAACAGATGTTGCGCGCACTTTTCAACGCCACGGCCCCTCTCACGCAGCGCCTGCCCCAGGGGTGCATTGTGGCCG
ATGACGGCGAGGGCGGTTTATTCCTCACACCAGAAGGCGCTGAAAACGCGGGCCTTTTCCTATATATTCACGGGGGTGGC
TTCACCATCGGCAGCCCGCGCACGCACCGCGCCATGGCCGCCCATATCGGGGCTGAGGCTGGTCTGCGGGTCCACCTGCC
CCGGTATTCCCTGGCGCCCGAGGCCCCATTTCCAGCCGCAATCACGCGCCTCAAACAGGTTTACGCCGCCCATGTCGCGC
GGGGCGATACGCCCGTAGCCGTGGGCGGTGACAGCGCGGGCGGCAACCTCGCCCTGCTTCTTACCCAAAACGCCGTGGCG
CATCAGTTGCCGCTGCCACGGGCCATGGTGTTGCTGGCTCCCGTCGTTGACTTCAGCCGCGACATCGCCGCCGAAGTGGC
AAATGCCCCGTCGGAAAACCTGTTGCCCGCCGCCTGGGCGCGCCGGGTGAAACACGCCTATACGCCAGAGGGTGTCGACC
TGAGCGACCCAAAGGTCTCGCCGATGTTTGGCGACTTGCAATCGCTGCCCCCCACTTTGATGCACCTGGCAACCGGCGAG
GCCCTGGCCGATCAATGCAAGACCATGGCCGCGCAGATGCCCGATTGCCGTGTGGACGAATGGCCCGGCCTGCAACATGT
CTGGCACCTCAAGGCAGGGGTCATGCCCGCCGCAACCCAAGCCTGCGCGGAGCTTGGGGCGTTTTTGCGGACGCACACAT
GA

Upstream 100 bases:

>100_bases
CGCAATTTTCCCAATGGCTTGGTGAGCAAGGCTATCAGGCGGGTATCGTCGAGACGGAATTTGGCGGAGAGGACCTTGAT
GAGGCCGAGGAGACGGCGGC

Downstream 100 bases:

>100_bases
AGGCCTTCGCCGCCCTTTTCACGACGCTGGATCAGACCACCAAGACCAGCGTGAAGACGGCCGCGCTGGCCGACTATTTC
CGCACGGCGCCCGAGGATGA

Product: alpha/beta hydrolase fold-3 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSVLTRADRISTWTARRIEKPLLSMIGSQQMLRALFNATAPLTQRLPQGCIVADDGEGGLFLTPEGAENAGLFLYIHGGG
FTIGSPRTHRAMAAHIGAEAGLRVHLPRYSLAPEAPFPAAITRLKQVYAAHVARGDTPVAVGGDSAGGNLALLLTQNAVA
HQLPLPRAMVLLAPVVDFSRDIAAEVANAPSENLLPAAWARRVKHAYTPEGVDLSDPKVSPMFGDLQSLPPTLMHLATGE
ALADQCKTMAAQMPDCRVDEWPGLQHVWHLKAGVMPAATQACAELGAFLRTHT

Sequences:

>Translated_293_residues
MSVLTRADRISTWTARRIEKPLLSMIGSQQMLRALFNATAPLTQRLPQGCIVADDGEGGLFLTPEGAENAGLFLYIHGGG
FTIGSPRTHRAMAAHIGAEAGLRVHLPRYSLAPEAPFPAAITRLKQVYAAHVARGDTPVAVGGDSAGGNLALLLTQNAVA
HQLPLPRAMVLLAPVVDFSRDIAAEVANAPSENLLPAAWARRVKHAYTPEGVDLSDPKVSPMFGDLQSLPPTLMHLATGE
ALADQCKTMAAQMPDCRVDEWPGLQHVWHLKAGVMPAATQACAELGAFLRTHT
>Mature_292_residues
SVLTRADRISTWTARRIEKPLLSMIGSQQMLRALFNATAPLTQRLPQGCIVADDGEGGLFLTPEGAENAGLFLYIHGGGF
TIGSPRTHRAMAAHIGAEAGLRVHLPRYSLAPEAPFPAAITRLKQVYAAHVARGDTPVAVGGDSAGGNLALLLTQNAVAH
QLPLPRAMVLLAPVVDFSRDIAAEVANAPSENLLPAAWARRVKHAYTPEGVDLSDPKVSPMFGDLQSLPPTLMHLATGEA
LADQCKTMAAQMPDCRVDEWPGLQHVWHLKAGVMPAATQACAELGAFLRTHT

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Secreted (Potential). Note=External to the cytoplasmic membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17567059, Length=269, Percent_Identity=24.907063197026, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.-

Molecular weight: Translated: 31175; Mature: 31044

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS01173 LIPASE_GDXG_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLTRADRISTWTARRIEKPLLSMIGSQQMLRALFNATAPLTQRLPQGCIVADDGEGGL
CCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCE
FLTPEGAENAGLFLYIHGGGFTIGSPRTHRAMAAHIGAEAGLRVHLPRYSLAPEAPFPAA
EECCCCCCCCCEEEEEECCCEECCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHH
ITRLKQVYAAHVARGDTPVAVGGDSAGGNLALLLTQNAVAHQLPLPRAMVLLAPVVDFSR
HHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHH
DIAAEVANAPSENLLPAAWARRVKHAYTPEGVDLSDPKVSPMFGDLQSLPPTLMHLATGE
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCH
ALADQCKTMAAQMPDCRVDEWPGLQHVWHLKAGVMPAATQACAELGAFLRTHT
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLTRADRISTWTARRIEKPLLSMIGSQQMLRALFNATAPLTQRLPQGCIVADDGEGGL
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCE
FLTPEGAENAGLFLYIHGGGFTIGSPRTHRAMAAHIGAEAGLRVHLPRYSLAPEAPFPAA
EECCCCCCCCCEEEEEECCCEECCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHH
ITRLKQVYAAHVARGDTPVAVGGDSAGGNLALLLTQNAVAHQLPLPRAMVLLAPVVDFSR
HHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHH
DIAAEVANAPSENLLPAAWARRVKHAYTPEGVDLSDPKVSPMFGDLQSLPPTLMHLATGE
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCH
ALADQCKTMAAQMPDCRVDEWPGLQHVWHLKAGVMPAATQACAELGAFLRTHT
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2545531 [H]